SPECC1L-ADORA2A

General Information

Gene Name       : SPECC1L-ADORA2A
Gene ID             : ENSG00000258555.6
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPECC1L-ADORA2A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPECC1L-ADORA2AENSG00000258555.60.000.050.03ENCSR000AEF
HepG2SPECC1L-ADORA2AENSG00000258555.60.000.070.04ENCSR985KAT
K562SPECC1L-ADORA2AENSG00000258555.60.030.000.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPECC1L-ADORA2A is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPECC1L-ADORA2A RNA is bound by 27 proteins.  







eCLIP assay for SPECC1L-ADORA2A is not avaliable on ENCORE database.





27 proteins are bound to SPECC1L-ADORA2A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr222481066924810737+3'-UTR,intron-Proximal5.198718.06720HepG2AKAP1
chr222481067124810743+3'-UTR,intron-Proximal5.9433615.41547HepG2UPF1
chr222483795424838042+3'-UTR4.027884.01760HepG2TIAL1
chr222483793824838066+3'-UTR4.521625.31599HepG2AKAP1
chr222475924724759287+3'-UTR,CDS3.169114.26492HepG2BCLAF1
chr222476146624761524+3'-UTR,CDS3.634585.74979HepG2GRWD1
chr222476522424765284+3'-UTR,CDS3.469124.02291HepG2GRWD1
chr222480766224807720+3'-UTR,CDS,intron-Distal,intron-Proximal3.704033.86479HepG2PRPF8
chr222475924224759303+3'-UTR,CDS3.092384.91547HepG2GRWD1
chr222480766924807710+3'-UTR,CDS,intron-Distal,intron-Proximal4.171313.59236HepG2AQR
chr222483795024838069+3'-UTR5.079777.70160HepG2UPF1
chr222469816224698225+3'-UTR,5'-UTR,CDS,intron-Proximal3.269905.74981HepG2GRWD1
chr222469817224698201+3'-UTR,5'-UTR,CDS3.728303.68471HepG2BCLAF1
chr222466680324666913+5'-UTR3.074577.09702HepG2DDX3X
chr222466687524666961+5'-UTR,intron-Proximal3.247057.46719HepG2NCBP2
chr222471868424718740+CDS,intron-Distal3.534783.80897HepG2FXR2
chr222473441124734441+CDS4.165284.23295HepG2GRWD1
chr222471788724717936+CDS,intron-Distal4.841835.85077HepG2FXR2
chr222471859024718758+CDS,intron-Distal3.558457.47194HepG2GRWD1
chr222471790424718038+CDS,intron-Distal3.836303.21664HepG2UCHL5
chr222471864424718772+CDS,intron-Distal4.1650715.85384HepG2BCLAF1
chr222471828224718327+CDS,intron-Distal3.310873.43213K562UCHL5
chr222473037724730395+CDS,intron-Proximal3.039113.45280HepG2BCLAF1
chr222471794024718054+CDS,intron-Distal4.196787.50845HepG2GRWD1
chr222473442324734488+CDS,intron-Proximal5.410297.02967HepG2PRPF8
chr222471797824718040+CDS,intron-Distal3.854756.13983HepG2HLTF
chr222472028324720347+CDS4.533787.97334HepG2BCLAF1
chr222473439824734432+CDS4.238603.71264HepG2FXR2
chr222471859324718696+CDS,intron-Distal3.359855.04943K562ZNF622
chr222471795124718030+CDS,intron-Distal4.713764.53233HepG2ZNF800
chr222472622224726275+CDS,intron-Proximal5.245648.25598HepG2PPIG
chr222471865124718724+CDS,intron-Distal3.813524.49347K562UCHL5
chr222471860724718651+CDS,intron-Distal3.589064.40383K562UCHL5
chr222471787124717933+CDS,intron-Distal3.503064.41784HepG2GRWD1
chr222472634624726400+CDS,intron-Proximal4.223047.16838HepG2BCLAF1
chr222471759024717719+CDS,intron-Distal3.2558810.13621HepG2BCLAF1
chr222472484124724889+CDS,intron-Proximal3.070783.47879HepG2PPIG
chr222471829824718367+CDS,intron-Distal3.576307.89260HepG2BCLAF1
chr222472622424726280+CDS4.428578.41475HepG2BCLAF1
chr222471735724717393+CDS,intron-Distal,intron-Proximal3.664079.25117K562YBX3
chr222470930724709338+3'-UTR,CDS4.567343.89826HepG2BCLAF1
chr222472622324726285+CDS,intron-Proximal3.691625.52031HepG2GRWD1
chr222473037624730454+CDS,intron-Proximal4.936355.97118HepG2FXR2
chr222471729724717400+CDS,intron-Distal,intron-Proximal3.394447.43909HepG2BCLAF1
chr222473037624730441+CDS,intron-Proximal3.305323.61259K562ZNF622
chr222473438124734433+CDS3.495385.15500HepG2BCLAF1
chr222471731924717465+CDS,intron-Distal,intron-Proximal3.687828.97406HepG2GRWD1
chr222481268224812794+3'-UTR,intron-Distal4.181637.44279HepG2GRSF1
chr222467875924678815+intron-Distal4.146513.21162HepG2HNRNPC
chr222477160224771655+intron-Distal4.794616.20441HepG2HLTF
chr222481126324811336+3'-UTR,intron-Distal5.7299911.61967K562UPF1
chr222481169924811759+3'-UTR,intron-Distal4.053827.95535HepG2AKAP1
chr222481112324811174+3'-UTR,intron-Distal4.921247.10674HepG2UPF1
chr222481152824811597+3'-UTR,intron-Distal4.7226917.08773K562UPF1
chr222482065824820716+intron-Distal3.460163.23466HepG2CSTF2T
chr222481140524811443+3'-UTR,intron-Distal3.295033.68605HepG2AKAP1
chr222481247024812537+3'-UTR,intron-Distal5.9341813.64218K562UPF1
chr222474601924746057+intron-Distal4.088733.86809HepG2SUGP2
chr222476727724767352+intron-Distal3.883363.95960K562SAFB2
chr222480060924800751+intron-Distal4.886537.87489HepG2HNRNPK
chr222481261324812698+3'-UTR,intron-Distal4.114977.84191HepG2UPF1
chr222482008424820150+intron-Distal3.977545.56645HepG2CSTF2T
chr222474589124745955+intron-Distal4.503775.35792HepG2SUGP2
chr222479809624798180+intron-Distal3.665855.34807K562ILF3
chr222481145824811528+3'-UTR,intron-Distal6.1416916.29100K562UPF1
chr222481286024812934+3'-UTR,intron-Distal4.245229.37691K562UPF1
chr222482001624820154+intron-Distal,intron-Proximal3.984213.63122HepG2PRPF4
chr222481313024813166+3'-UTR,intron-Distal5.030926.81621K562UPF1
chr222481264324812683+3'-UTR,intron-Distal3.922967.71860K562UPF1
chr222481238624812462+3'-UTR,intron-Distal5.7772833.83289K562UPF1
chr222474574824745851+intron-Distal5.3399811.58997HepG2SUGP2
chr222479809324798181+intron-Distal6.3578878.94663HepG2PCBP2
chr222481117724811320+3'-UTR,intron-Distal5.4972423.50738HepG2UPF1
chr222481096524811088+3'-UTR,intron-Distal4.4364614.61601HepG2UPF1
chr222479806924798185+intron-Distal5.9668636.59016HepG2HNRNPK
chr222480336324803442+intron-Distal3.211294.67779HepG2SUGP2
chr222481094224811031+3'-UTR,intron-Distal4.4339110.03265HepG2AKAP1
chr222477113224771181+intron-Distal3.936503.26547HepG2HLTF
chr222481088324810916+3'-UTR,intron-Distal3.229143.44343HepG2AKAP1
chr222475511624755195+intron-Distal4.978054.40618K562PTBP1
chr222481104324811106+3'-UTR,intron-Distal4.985177.27295HepG2AKAP1
chr222475511624755182+intron-Distal3.646306.10762HepG2PTBP1
chr222481239024812445+3'-UTR,intron-Distal4.107287.95535HepG2AKAP1
chr222477105824771182+intron-Distal3.846473.12651K562SAFB2
chr222482045724820561+5'-UTR,intron-Distal,intron-Proximal5.221597.09999HepG2CSTF2T
chr222479809724798202+intron-Distal5.8513113.53164HepG2ILF3
chr222481116724811247+3'-UTR,intron-Distal5.5044312.24108HepG2AKAP1
chr222481260024812643+3'-UTR,intron-Distal4.456377.83400K562UPF1
chr222481171124811762+3'-UTR,intron-Distal4.583666.20043HepG2UPF1
chr222474460924744698+intron-Distal3.222475.12506HepG2SUGP2
chr222474608424746134+intron-Distal3.207253.59523HepG2SUGP2
chr222481082324810849+3'-UTR,intron-Distal3.967363.08342HepG2AKAP1
chr222479808924798250+intron-Distal4.3235315.61714HepG2DDX59
chr222481074324810806+3'-UTR,intron-Proximal5.5142511.27805HepG2UPF1
chr222476529324765314+intron-Proximal4.377103.71570HepG2BCLAF1
chr222481073724810792+3'-UTR,intron-Proximal5.073068.89452HepG2AKAP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPECC1L-ADORA2A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPECC1L-ADORA2A is not available on ENCORE database.

  • 33 RBPs can affect the levels of SPECC1L-ADORA2A.  








The Knockdown/knockout RNA-Seq assay for SPECC1L-ADORA2A is not available on ENCORE database.





33 RBPs can affect the gene expression of SPECC1L-ADORA2A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPECC1L-ADORA2AENSG00000258555.211.862000.0000099999.999903.623702.94480HepG2ACO1
SPECC1L-ADORA2AENSG00000258555.211.785500.0000099999.999903.566402.70800HepG2AKAP8L
SPECC1L-ADORA2AENSG00000258555.22.4487020.10020-3.037103.177501.39080HepG2APOBEC3C
SPECC1L-ADORA2AENSG00000258555.216.112900.0000099999.999903.962502.30000HepG2ATP5C1
SPECC1L-ADORA2AENSG00000258555.239.997200.0000099999.999902.889902.19060HepG2AUH
SPECC1L-ADORA2AENSG00000258555.216.323300.0000099999.999904.360502.98860HepG2CPSF7
SPECC1L-ADORA2AENSG00000258555.220.882200.0000099999.999905.335303.86760HepG2ESF1
SPECC1L-ADORA2AENSG00000258555.215.286900.0000099999.999901.905201.38630HepG2ETF1
SPECC1L-ADORA2AENSG00000258555.20.0000019.92460-99999.999996.301604.61880HepG2GRSF1
SPECC1L-ADORA2AENSG00000258555.211.617000.0000099999.999903.553601.71780HepG2CCAR2
SPECC1L-ADORA2AENSG00000258555.223.162700.0000099999.999902.245001.32440HepG2KIF1C
SPECC1L-ADORA2AENSG00000258555.20.0000019.67330-99999.999996.138304.78050HepG2PABPC1
SPECC1L-ADORA2AENSG00000258555.224.120400.0000099999.999907.754806.24440HepG2RPS10
SPECC1L-ADORA2AENSG00000258555.210.206300.0000099999.999902.579501.80580HepG2RPS2
SPECC1L-ADORA2AENSG00000258555.211.721500.0000099999.999903.353701.67030HepG2RTF1
SPECC1L-ADORA2AENSG00000258555.233.194400.0000099999.999904.011602.30950HepG2SF1
SPECC1L-ADORA2AENSG00000258555.218.549103.786302.292401.928301.33630HepG2SRSF7
SPECC1L-ADORA2AENSG00000258555.20.0000021.84540-99999.999995.939305.15730K562AGGF1
SPECC1L-ADORA2AENSG00000258555.24.6749023.99680-2.359802.489101.56520K562AKAP8
SPECC1L-ADORA2AENSG00000258555.20.0000022.72920-99999.999996.560005.52230K562AKAP8L
SPECC1L-ADORA2AENSG00000258555.20.0000023.84460-99999.999997.341405.75170K562ATP5C1
SPECC1L-ADORA2AENSG00000258555.20.0000026.11290-99999.999998.223606.17910K562CCDC124
SPECC1L-ADORA2AENSG00000258555.20.0000031.88670-99999.999992.506801.50550K562CNOT7
SPECC1L-ADORA2AENSG00000258555.247.299700.0000099999.999903.889602.77860K562EIF4G2
SPECC1L-ADORA2AENSG00000258555.20.000009.32940-99999.999992.829201.74470K562HNRNPA1
SPECC1L-ADORA2AENSG00000258555.213.471700.0000099999.999902.084001.55620K562HNRNPC
SPECC1L-ADORA2AENSG00000258555.20.0000010.33200-99999.999993.270902.30200K562HNRNPU
SPECC1L-ADORA2AENSG00000258555.213.572200.0000099999.999903.828101.49960K562CCAR2
SPECC1L-ADORA2AENSG00000258555.23.1808024.12820-2.923203.029502.16280K562KIF1C
SPECC1L-ADORA2AENSG00000258555.20.0000023.09100-99999.999996.344204.44820K562MAK16
SPECC1L-ADORA2AENSG00000258555.20.0000027.02880-99999.999998.485906.71060K562MBNL1
SPECC1L-ADORA2AENSG00000258555.20.0000010.22370-99999.999993.255601.55300K562PKM
SPECC1L-ADORA2AENSG00000258555.20.0000022.55520-99999.999995.877205.12240K562PUS1
SPECC1L-ADORA2AENSG00000258555.20.0000021.96500-99999.999996.098305.24370K562RBM15
SPECC1L-ADORA2AENSG00000258555.20.000009.90280-99999.999993.237401.41070K562UPF2
SPECC1L-ADORA2AENSG00000258555.20.0000022.85430-99999.999996.199204.07610K562UTP18
SPECC1L-ADORA2AENSG00000258555.224.134900.0000099999.999904.852703.76020K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPECC1L-ADORA2A is not available on ENCORE database.





2 RBPs can affect the splicing of SPECC1L-ADORA2A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSSPECC1L-ADORA2AENSG00000258555.2chr22+247172552471888624717255247172912472018724720395-0.109000.001460.08853shorterHepG2SF3A3
MXESPECC1L-ADORA2AENSG00000258555.2chr22+24672667246727712469816224698352246668652466695124709280247094340.131000.001660.091831includedHepG2SRSF7

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPECC1L-ADORA2A is not avaliable on ENCORE database.