GOSR2

General Information

Gene Name       : GOSR2
Gene ID             : ENSG00000108433.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GOSR2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GOSR2ENSG00000108433.1622.0024.2823.14ENCSR000AEF
HepG2GOSR2ENSG00000108433.1637.8745.9441.91ENCSR985KAT
K562GOSR2ENSG00000108433.1629.6129.5529.58ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GOSR2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GOSR2 RNA is bound by 31 proteins.  







eCLIP assay for GOSR2 is not avaliable on ENCORE database.





31 proteins are bound to GOSR2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr174501622445016313+3'-UTR,intron-Distal,polyA_site4.6746124.37861K562TARDBP
chr174501659345016670+3'-UTR,intron-Distal4.8849825.53334K562UPF1
chr174501698745017098+3'-UTR,intron-Distal3.3532932.36957K562UPF1
chr174501691245016958+3'-UTR,intron-Distal4.3065017.28969K562UPF1
chr174501686445016922+3'-UTR,intron-Distal3.314934.06711K562AKAP1
chr174501655645016594+3'-UTR,intron-Distal3.827183.30425K562LIN28B
chr174501702345017093+3'-UTR,intron-Distal3.736078.71584K562IGF2BP2
chr174501623445016294+3'-UTR,intron-Distal,polyA_site4.014924.45240K562EIF4G2
chr174501616845016217+3'-UTR,intron-Distal,intron-Proximal4.637594.36861HepG2SRSF7
chr174501660545016653+3'-UTR,intron-Distal3.912353.06084HepG2HNRNPK
chr174501605745016156+3'-UTR,CDS,intron-Proximal4.6667810.79362K562LIN28B
chr174501700245017090+3'-UTR,intron-Distal3.2329712.73639K562FAM120A
chr174501683845016912+3'-UTR,intron-Distal4.0645637.13355K562UPF1
chr174501617245016224+3'-UTR,intron-Distal4.9626432.02430K562TARDBP
chr174501711745017179+3'-UTR,intron-Distal4.0554812.54016K562UPF1
chr174500688445006899+5'-UTR,CDS,intron-Proximal4.053725.63105K562DDX3X
chr174500686745006965+5'-UTR,CDS,intron-Proximal3.337806.93074HepG2BUD13
chr174500688945006951+5'-UTR,CDS,intron-Proximal3.577969.44988HepG2PPIG
chr174500689945006948+5'-UTR,CDS3.463256.60215K562DDX3X
chr174500690045006942+5'-UTR,CDS3.188936.79825HepG2GRWD1
chr174500051045000561+5'-UTR,CDS3.479466.40214HepG2NCBP2
chr174500056145000593+5'-UTR,CDS,intron-Proximal4.006206.09067HepG2NCBP2
chr174500058045000627+5'-UTR,CDS,intron-Proximal4.256273.59236HepG2AQR
chr174500052045000589+5'-UTR,CDS,intron-Proximal3.945858.88978K562DDX3X
chr174500955045009601+CDS,intron-Proximal4.314013.93614HepG2AQR
chr174501602745016119+CDS,intron-Proximal3.3262211.18765HepG2PPIG
chr174500694845007031+CDS,intron-Proximal3.743367.64728K562AQR
chr174501600945016048+CDS3.880583.39593HepG2PRPF4
chr174501248745012527+CDS,intron-Distal4.0541714.97716HepG2PPIG
chr174501606445016107+CDS,intron-Proximal4.3141516.82955HepG2PRPF8
chr174500956545009598+CDS,intron-Proximal3.464894.88100K562AQR
chr174501605645016112+CDS,intron-Proximal3.8342113.69709HepG2GRWD1
chr174501594545015994+CDS,intron-Proximal3.8246123.73826HepG2U2AF2
chr174500691845007022+CDS,intron-Proximal3.056308.02352HepG2PRPF8
chr174501243745012475+CDS,intron-Distal3.439725.18023HepG2GRWD1
chr174500847045008570+CDS4.3152810.74047HepG2GRWD1
chr174501596145016013+CDS,intron-Proximal3.3493316.24042HepG2PPIG
chr174501594445016001+CDS,intron-Proximal4.5642910.92416K562U2AF2
chr174504383945043905+CDS,intron-Proximal4.110003.50006HepG2SF3B4
chr174500848545008510+CDS3.200854.08171K562YBX3
chr174500956045009607+CDS,intron-Proximal4.3560313.26139HepG2PRPF8
chr174501601845016056+CDS4.6553713.23869HepG2GRWD1
chr174502084045020923+intron-Distal3.806309.06898HepG2HNRNPK
chr174503822245038275+intron-Distal3.746107.94789HepG2HLTF
chr174501752745017563+intron-Distal3.1407013.85515K562UPF1
chr174501770445017736+intron-Distal4.8510912.17194K562UPF1
chr174503383745033889+intron-Distal3.828887.11398HepG2HNRNPC
chr174503284845032896+intron-Distal3.058414.23271HepG2HNRNPM
chr174502443345024545+intron-Distal4.109824.10765K562HNRNPA1
chr174501439545014443+intron-Distal3.625804.61500HepG2HNRNPM
chr174501762345017667+intron-Distal3.7562213.56677K562UPF1
chr174501742845017520+intron-Distal3.5424625.25021HepG2PTBP1
chr174504350345043555+intron-Distal3.794803.64762HepG2QKI
chr174501816645018210+intron-Distal4.0272913.82382K562UPF1
chr174501926345019312+intron-Distal4.460419.43510K562UPF1
chr174502774045027816+intron-Distal4.142713.43967HepG2TAF15
chr174503719745037269+intron-Distal4.785066.09701HepG2SRSF9
chr174503978245039859+intron-Distal3.051093.01110HepG2HLTF
chr174501743145017535+intron-Distal3.1063510.03961K562PTBP1
chr174503768645037763+intron-Distal3.845579.10042HepG2HLTF
chr174501774845017786+intron-Distal5.4696117.60288K562UPF1
chr174504228145042316+intron-Distal3.089503.07152HepG2HLTF
chr174502452445024610+intron-Distal3.187785.84594HepG2HNRNPU
chr174503726945037363+intron-Distal4.741336.95446HepG2SRSF9
chr174501781145017852+intron-Distal,intron-Proximal3.9138515.05756K562UPF1
chr174501878845018842+intron-Distal3.3591613.57440K562UPF1
chr174501745045017530+intron-Distal3.2519527.72430HepG2PCBP2
chr174504965245049738+intron-Distal4.138467.54289HepG2PTBP1
chr174502252445022584+intron-Distal3.492374.20880HepG2GTF2F1
chr174504342945043503+intron-Distal6.0609311.50595HepG2QKI
chr174503765645037686+intron-Distal3.311303.61820HepG2HLTF
chr174501004845010156+intron-Distal3.794273.08314K562TARDBP
chr174501454645014596+intron-Distal3.578184.97523HepG2HNRNPM
chr174501743845017527+intron-Distal3.6243541.99353K562UPF1
chr174501777445017848+intron-Distal,intron-Proximal3.899903.66583K562AKAP1
chr174503815945038190+intron-Distal4.311304.42137HepG2HLTF
chr174504338145043429+intron-Distal4.955776.23638HepG2QKI
chr174501917845019259+intron-Distal3.403269.62434K562UPF1
chr174500857345008611+intron-Proximal4.131423.31283K562PRPF8
chr174500857445008614+intron-Proximal4.932626.04760K562AQR
chr174500696045007002+intron-Proximal3.324933.54718K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GOSR2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GOSR2 is not available on ENCORE database.

  • 70 RBPs can affect the levels of GOSR2.  








The Knockdown/knockout RNA-Seq assay for GOSR2 is not available on ENCORE database.





70 RBPs can affect the gene expression of GOSR2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GOSR2ENSG00000108433.11601.31320755.53780-0.329403.074802.43860HepG2ACO1
GOSR2ENSG00000108433.11354.69620581.64680-0.713606.122004.71550HepG2ADAR
GOSR2ENSG00000108433.11539.16390759.11780-0.493605.634704.57460HepG2AKAP8L
GOSR2ENSG00000108433.11944.53290773.329100.288401.796501.30510HepG2BOP1
GOSR2ENSG00000108433.11583.75200755.41010-0.371903.877403.11530HepG2CKAP4
GOSR2ENSG00000108433.11938.73240795.997300.237902.017001.45190HepG2CELF1
GOSR2ENSG00000108433.11535.80680698.78100-0.383104.108003.11480HepG2DDX19B
GOSR2ENSG00000108433.11901.72090532.860100.758809.002607.85260HepG2DDX21
GOSR2ENSG00000108433.11931.39450696.746400.418703.088802.02760HepG2DDX5
GOSR2ENSG00000108433.11820.49070593.692400.466703.120602.49190HepG2EIF2S1
GOSR2ENSG00000108433.11868.18720656.046600.404102.335401.74620HepG2EIF4A3
GOSR2ENSG00000108433.11993.690701182.52940-0.251002.467201.89420HepG2ETF1
GOSR2ENSG00000108433.11381.67000804.80470-1.0763012.0098010.75820HepG2GPKOW
GOSR2ENSG00000108433.11787.22780591.326700.412702.842702.18730HepG2HNRNPA1
GOSR2ENSG00000108433.11822.03510606.630400.438303.898202.78880HepG2HNRNPM
GOSR2ENSG00000108433.11850.14010624.184800.445602.971702.27600HepG2IGF2BP2
GOSR2ENSG00000108433.11559.30710667.40430-0.254902.037801.39740HepG2ILF2
GOSR2ENSG00000108433.11541.44030690.67900-0.351203.388702.26000HepG2KIF1C
GOSR2ENSG00000108433.111032.28940662.316600.640205.819504.87870HepG2MAGOH
GOSR2ENSG00000108433.11866.95920665.997300.380302.067001.51620HepG2MATR3
GOSR2ENSG00000108433.11954.50740711.636600.423503.767302.82730HepG2MSI2
GOSR2ENSG00000108433.11421.25860681.00770-0.693005.869504.80460HepG2NSUN2
GOSR2ENSG00000108433.11751.58140593.867300.339703.004402.37560HepG2PCBP1
GOSR2ENSG00000108433.11415.33070582.76170-0.488604.399603.48960HepG2PPIL4
GOSR2ENSG00000108433.11908.82700604.292300.588708.248707.40860HepG2PTBP1
GOSR2ENSG00000108433.111005.66110859.984100.225702.418801.85690HepG2PUM1
GOSR2ENSG00000108433.111021.37580769.569600.408305.267604.46720HepG2PUS1
GOSR2ENSG00000108433.11607.38500760.21190-0.323801.926101.33070HepG2SF3B1
GOSR2ENSG00000108433.11852.31820591.598100.526703.152402.12260HepG2SMNDC1
GOSR2ENSG00000108433.11850.857501116.31520-0.391804.802804.19450HepG2SRFBP1
GOSR2ENSG00000108433.11988.70090656.680900.590208.645807.91600HepG2SRSF1
GOSR2ENSG00000108433.11592.55490817.97700-0.465102.660101.68060HepG2SRSF3
GOSR2ENSG00000108433.11657.59690799.89050-0.282602.070601.51950HepG2SRSF5
GOSR2ENSG00000108433.11712.63650927.89170-0.380804.173503.34480HepG2SRSF7
GOSR2ENSG00000108433.11282.49100394.53870-0.482002.311201.32110HepG2STIP1
GOSR2ENSG00000108433.11343.47460590.27110-0.781209.201208.27430HepG2TAF15
GOSR2ENSG00000108433.11455.30860640.54640-0.492505.182904.46030HepG2TRIM56
GOSR2ENSG00000108433.11489.87450752.08630-0.618504.737003.92760HepG2U2AF1
GOSR2ENSG00000108433.11959.50150718.224600.417704.974304.21120HepG2UTP3
GOSR2ENSG00000108433.11480.27520633.09620-0.398602.212901.55840HepG2XRN2
GOSR2ENSG00000108433.111016.18100818.169100.312603.672703.06700HepG2ZNF622
GOSR2ENSG00000108433.11399.35050579.83600-0.538002.991201.64040HepG2ZRANB2
GOSR2ENSG00000108433.111084.055701634.20200-0.5921011.6218010.55290K562AGGF1
GOSR2ENSG00000108433.111138.080001700.45010-0.579307.155206.06270K562AKAP8L
GOSR2ENSG00000108433.11491.97460642.26240-0.384602.319401.37110K562CCAR1
GOSR2ENSG00000108433.111531.414201952.99750-0.350803.793902.38330K562CCDC124
GOSR2ENSG00000108433.111497.481901142.140800.390703.410001.97700K562CIRBP
GOSR2ENSG00000108433.111373.306701917.36550-0.481505.017903.01830K562DDX19B
GOSR2ENSG00000108433.111926.816301446.073500.414006.720605.76950K562DDX47
GOSR2ENSG00000108433.11511.29700690.66590-0.433803.049601.63920K562DNAJC21
GOSR2ENSG00000108433.11634.03900887.14650-0.484603.618702.56380K562EFTUD2
GOSR2ENSG00000108433.111258.677101000.252800.331403.745202.31730K562EIF2S1
GOSR2ENSG00000108433.111133.82480728.981000.637109.328207.86980K562EIF3G
GOSR2ENSG00000108433.111247.55710951.393900.390903.321402.42620K562EIF4A3
GOSR2ENSG00000108433.111501.086302027.62030-0.433806.789005.33920K562EIF4G2
GOSR2ENSG00000108433.11650.61660830.46740-0.352102.815101.51010K562EWSR1
GOSR2ENSG00000108433.11742.33090951.82480-0.358602.423601.62080K562FMR1
GOSR2ENSG00000108433.11553.71640806.74820-0.543004.129402.99340K562FTO
GOSR2ENSG00000108433.11661.46410857.79350-0.375001.919401.34220K562G3BP2
GOSR2ENSG00000108433.111137.18470893.177900.348302.677201.89480K562GPKOW
GOSR2ENSG00000108433.111329.70080942.465200.496505.358904.55350K562HNRNPC
GOSR2ENSG00000108433.111262.36360842.989800.582405.138303.82500K562HNRNPM
GOSR2ENSG00000108433.111685.324701389.424100.278401.984501.30560K562HSPD1
GOSR2ENSG00000108433.111217.441501804.64180-0.567906.738805.31940K562KIF1C
GOSR2ENSG00000108433.111542.704802021.64920-0.390104.438403.23360K562MBNL1
GOSR2ENSG00000108433.111016.657901417.02620-0.479003.102102.16040K562NAA15
GOSR2ENSG00000108433.111041.374201212.97440-0.220102.290501.60560K562NSUN2
GOSR2ENSG00000108433.11698.31190996.42600-0.512904.790303.49570K562PCBP2
GOSR2ENSG00000108433.111889.229002305.52370-0.287303.706402.59270K562PUM2
GOSR2ENSG00000108433.111096.974501686.46010-0.620507.012406.19350K562PUS1
GOSR2ENSG00000108433.111097.943101643.13480-0.581609.423208.35250K562RBM15
GOSR2ENSG00000108433.111079.48300771.144300.485205.118903.76580K562RCC2
GOSR2ENSG00000108433.111595.70780879.407400.8595010.410808.79930K562RPS19
GOSR2ENSG00000108433.111470.391301196.956900.296703.131902.26480K562SF3A3
GOSR2ENSG00000108433.111147.79440891.485100.364503.368802.42380K562SF3B4
GOSR2ENSG00000108433.11520.06850707.46180-0.444003.259401.87640K562SLBP
GOSR2ENSG00000108433.11678.918701107.87880-0.706503.065001.74820K562SNRNP200
GOSR2ENSG00000108433.112206.599101286.145700.7787023.6585021.81440K562UPF1
GOSR2ENSG00000108433.111371.019501144.437900.260503.035102.15010K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GOSR2 is not available on ENCORE database.





17 RBPs can affect the splicing of GOSR2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGOSR2ENSG00000108433.11chr17+450123944501253545009432450095654501596445016277-0.113000.000000.00002excludedHepG2U2AF1
SEGOSR2ENSG00000108433.11chr17+450084644500857345006885450069504500943245009565-0.070000.002050.03722excludedHepG2U2AF1
SEGOSR2ENSG00000108433.11chr17+450123944501259145009432450095654501596445016277-0.060000.000630.02178excludedK562AKAP8L
SEGOSR2ENSG00000108433.11chr17+450123944501253545009432450095654501596445016277-0.110000.000000.00006excludedHepG2U2AF2
SEGOSR2ENSG00000108433.11chr17+450084644500857345006885450069504500943245009565-0.072000.001270.01728excludedHepG2U2AF2
SEGOSR2ENSG00000108433.11chr17+4501239445012535450094324500956545015964450162770.076000.001060.04123includedK562FXR1
SEGOSR2ENSG00000108433.11chr17+450094324500956545006885450069504501239445012535-0.194000.000000.00000excludedHepG2SRSF7
SEGOSR2ENSG00000108433.11chr17+450123944501253545009432450095654501596445016277-0.062000.000020.00070excludedK562PUS1
SEGOSR2ENSG00000108433.11chr17+4501239445012535450094324500956545015964450162770.069000.000080.02821includedK562FXR2
SEGOSR2ENSG00000108433.11chr17+450094324500956545006885450069504501239445012535-0.059000.000420.06593excludedK562SRSF7
SEGOSR2ENSG00000108433.11chr17+450123944501253545009432450095654501596445016277-0.056000.000050.00325excludedK562UTP18
SEGOSR2ENSG00000108433.11chr17+450123944501253545009432450095654501596445016277-0.065000.001910.06180excludedK562HNRNPU
SEGOSR2ENSG00000108433.11chr17+450123944501253545009432450095654501596445016277-0.054000.000190.00740excludedK562RBM15
A3SSGOSR2ENSG00000108433.11chr17+4500841745008573450084644500857345006794450069500.052000.000010.00006longerK562AQR
A5SSGOSR2ENSG00000108433.11chr17+4501237445012591450123744501253545015964450162770.130000.000000.00000longerK562AQR
A5SSGOSR2ENSG00000108433.11chr17+4501239445012591450123944501253545015964450162770.116000.000010.00261longerK562EFTUD2
A5SSGOSR2ENSG00000108433.11chr17+4501239445012591450123944501253545015964450162770.132000.000030.00756longerHepG2PRPF8
MXEGOSR2ENSG00000108433.11chr17+45009432450095654501239445012535450068854500695045015964450160700.258000.000000.000031includedHepG2U2AF1
MXEGOSR2ENSG00000108433.11chr17+4500846445008573450094324500956545006885450069504501596445016070-0.299000.000000.000002includedHepG2U2AF1
MXEGOSR2ENSG00000108433.11chr17+45009432450095654501239445012535450068854500695045015964450160700.123000.002880.053001includedHepG2SRSF1
MXEGOSR2ENSG00000108433.11chr17+45008464450085734501239445012535450068854500695045015964450160700.163000.001250.023711includedK562U2AF1
MXEGOSR2ENSG00000108433.11chr17+45008467450085734501239445012535450068854500695045015964450160910.074000.008760.092191includedK562U2AF1
MXEGOSR2ENSG00000108433.11chr17+45008464450085734500943245009565450068854500695045012394450142050.134000.000000.000121includedK562PUS1
MXEGOSR2ENSG00000108433.11chr17+45008464450085734501239445012535450068854500695045015964450160700.131000.001120.022101includedK562PUS1
MXEGOSR2ENSG00000108433.11chr17+45009432450095654501239445012535450068854500695045015964450160700.112000.000050.001741includedK562PUS1
MXEGOSR2ENSG00000108433.11chr17+4500943245009565450123944501253545006885450069504501596445016070-0.087000.002490.080822includedK562FXR1
MXEGOSR2ENSG00000108433.11chr17+45008467450085734500943245009565450068854500695045012394450125350.058000.000650.011241includedK562U2AF2
MXEGOSR2ENSG00000108433.11chr17+45009432450095654501239445012535450068854500695045015964450160700.287000.000000.000001includedHepG2U2AF2
MXEGOSR2ENSG00000108433.11chr17+45009432450095654501239445012535450068854500695045015964450160700.076000.005850.096491includedK562SBDS
MXEGOSR2ENSG00000108433.11chr17+45009432450095654501239445012535450084644500857345015964450160700.120000.000370.023721includedK562SAFB
MXEGOSR2ENSG00000108433.11chr17+45009432450095654501239445012535450068854500695045015964450160700.115000.000140.016041includedHepG2SRSF7
MXEGOSR2ENSG00000108433.11chr17+4500943245009565450123944501253545006885450069504501596445016070-0.088000.000570.037502includedHepG2LARP4
MXEGOSR2ENSG00000108433.11chr17+45008464450085734500943245009565450068854500695045012394450142050.129000.006200.087921includedK562PRPF8
MXEGOSR2ENSG00000108433.11chr17+45008464450085734500943245009565450068854500695045012394450142050.078000.003500.096611includedK562AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GOSR2 is not avaliable on ENCORE database.