GCFC2

General Information

Gene Name       : GCFC2
Gene ID             : ENSG00000005436.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GCFC2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GCFC2ENSG00000005436.1319.1518.5918.87ENCSR000AEF
HepG2GCFC2ENSG00000005436.1317.5936.2526.92ENCSR985KAT
K562GCFC2ENSG00000005436.1317.0316.3416.69ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GCFC2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GCFC2 RNA is bound by 16 proteins.  







eCLIP assay for GCFC2 is not avaliable on ENCORE database.





16 proteins are bound to GCFC2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr27589181475891857-3'-UTR,CDS,intron-Distal4.665304.78529HepG2BCLAF1
chr27592948575929575-5'-UTR,CDS,intron-Distal,intron-Proximal4.2049615.43672HepG2U2AF2
chr27591713975917209-5'-UTR,CDS,intron-Distal,intron-Proximal4.264313.59941K562UCHL5
chr27591491175914973-5'-UTR,CDS,intron-Distal,intron-Proximal5.642173.70131HepG2PRPF8
chr27593778075938002-5'-UTR,CDS,intron-Distal,intron-Proximal4.2808910.32664HepG2SRSF1
chr27592939075929473-5'-UTR,CDS,intron-Distal,intron-Proximal3.515407.24602HepG2GRWD1
chr27591777375917823-5'-UTR,CDS,intron-Distal3.331594.85828HepG2BCLAF1
chr27591920275919221-5'-UTR,CDS,intron-Distal4.130113.38968HepG2BCLAF1
chr27592831375928438-5'-UTR,CDS,intron-Distal,intron-Proximal4.972226.78062HepG2TRA2A
chr27591620975916298-5'-UTR,CDS,intron-Distal4.2269912.93761HepG2BCLAF1
chr27592830775928427-5'-UTR,CDS,intron-Distal,intron-Proximal4.9053511.13876HepG2BCLAF1
chr27593757275937700-5'-UTR,CDS,intron-Distal3.535489.91754HepG2EFTUD2
chr27592947875929584-5'-UTR,CDS,intron-Distal,intron-Proximal4.395426.14774K562U2AF2
chr27591494275915068-5'-UTR,CDS,intron-Distal,intron-Proximal4.1617112.07231HepG2BCLAF1
chr27591709475917128-5'-UTR,CDS,intron-Distal,intron-Proximal4.791076.04243HepG2BCLAF1
chr27591715275917201-5'-UTR,CDS,intron-Distal3.872824.93978HepG2BCLAF1
chr27593785275937963-CDS,intron-Distal4.212863.33119HepG2SRSF9
chr27593789775937956-CDS,intron-Distal4.008953.32488HepG2DDX3X
chr27593779875937941-CDS,intron-Distal,intron-Proximal3.287835.18023HepG2GRWD1
chr27591321675913239-intron-Distal5.8508027.34652HepG2QKI
chr27591115775911229-intron-Distal3.910666.51675HepG2SUGP2
chr27591323975913299-intron-Distal5.7250420.24885HepG2QKI
chr27591101275911063-intron-Distal4.060277.29258HepG2SUGP2
chr27591318475913239-intron-Distal3.648593.22008K562QKI
chr27590945875909500-intron-Distal4.213444.31720HepG2MATR3
chr27590996175910031-intron-Distal3.433523.00914HepG2PTBP1
chr27591470175914774-intron-Distal4.990965.58765HepG2QKI
chr27592968475929705-intron-Distal4.151573.35169HepG2U2AF2
chr27593160975931691-intron-Distal3.480724.31768HepG2KHSRP
chr27591082175910868-intron-Distal4.082984.03915HepG2SUGP2
chr27591323975913304-intron-Distal4.552273.78039K562QKI
chr27591432275914376-intron-Distal4.929655.85495HepG2QKI
chr27590994875910020-intron-Distal4.340548.01961HepG2MATR3
chr27591118175911229-intron-Distal4.224214.05620HepG2MATR3
chr27590995475910019-intron-Distal4.088736.77642HepG2SUGP2
chr27591381575913875-intron-Distal4.633526.79309HepG2ILF3
chr27591477975914854-intron-Distal,intron-Proximal3.280453.29213HepG2KHSRP
chr27593103675931132-intron-Distal3.095995.54123HepG2QKI
chr27591101475911113-intron-Distal4.007734.28254HepG2MATR3
chr27591014275910196-intron-Distal3.357953.10961HepG2MATR3
chr27591315575913216-intron-Distal6.9706434.88565HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GCFC2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GCFC2 is not available on ENCORE database.

  • 73 RBPs can affect the levels of GCFC2.  








The Knockdown/knockout RNA-Seq assay for GCFC2 is not available on ENCORE database.





73 RBPs can affect the gene expression of GCFC2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GCFC2ENSG00000005436.9473.43590600.49160-0.343002.816602.20440HepG2ACO1
GCFC2ENSG00000005436.9572.13730854.99040-0.579504.605103.60450HepG2ASCC1
GCFC2ENSG00000005436.9313.31200489.86860-0.644803.663702.63970HepG2BCLAF1
GCFC2ENSG00000005436.9326.59280454.25060-0.476002.536701.87360HepG2CPSF6
GCFC2ENSG00000005436.9647.21500828.41560-0.356102.475801.86120HepG2CELF1
GCFC2ENSG00000005436.9356.04850554.22450-0.638403.517502.65870HepG2DDX55
GCFC2ENSG00000005436.9305.91170850.17590-1.4746020.1150018.65430HepG2DDX6
GCFC2ENSG00000005436.9367.11040463.99810-0.337902.478401.85530HepG2DNAJC2
GCFC2ENSG00000005436.9436.75900817.44270-0.904308.325307.33560HepG2EIF2S1
GCFC2ENSG00000005436.9636.25750903.44180-0.505803.332902.63270HepG2EIF4A3
GCFC2ENSG00000005436.91213.01000878.806100.464905.726604.59720HepG2EIF4G1
GCFC2ENSG00000005436.9716.37460497.313600.526504.140902.82930HepG2ESF1
GCFC2ENSG00000005436.9972.372701140.79020-0.230501.913301.39370HepG2ETF1
GCFC2ENSG00000005436.9572.20610911.31830-0.671406.063505.06480HepG2FXR1
GCFC2ENSG00000005436.9393.16580620.42040-0.658104.599303.28170HepG2GNB2L1
GCFC2ENSG00000005436.9830.36010491.429900.756707.527106.54670HepG2HNRNPLL
GCFC2ENSG00000005436.9372.13180522.27190-0.489004.505103.74790HepG2HNRNPU
GCFC2ENSG00000005436.9328.97860469.21740-0.512303.178102.31390HepG2MSI2
GCFC2ENSG00000005436.9661.59520938.39690-0.504203.582002.86550HepG2NCBP2
GCFC2ENSG00000005436.9627.79080883.46430-0.492904.048503.12580HepG2NOL12
GCFC2ENSG00000005436.9280.11370469.70480-0.745703.719202.67760HepG2PABPC1
GCFC2ENSG00000005436.9586.84250823.50630-0.488805.159204.46060HepG2PTBP1
GCFC2ENSG00000005436.9409.96390843.28530-1.0405012.2704011.13360HepG2PUF60
GCFC2ENSG00000005436.9688.68160894.50480-0.377303.055802.35040HepG2PUM2
GCFC2ENSG00000005436.91321.73500891.847100.567507.913406.94040HepG2QKI
GCFC2ENSG00000005436.9785.27470953.48490-0.280002.250701.77010HepG2RBM22
GCFC2ENSG00000005436.9568.12150809.42010-0.510704.622003.76990HepG2RBM25
GCFC2ENSG00000005436.9856.16910602.516700.506802.608901.68940HepG2RPS10
GCFC2ENSG00000005436.9779.72400485.755200.682605.087203.31200HepG2SART3
GCFC2ENSG00000005436.9802.17530490.200200.710404.268802.36050HepG2SBDS
GCFC2ENSG00000005436.9783.84240486.434800.688206.771905.70940HepG2SF3B1
GCFC2ENSG00000005436.9414.70830542.42620-0.387302.274701.68170HepG2SMN1
GCFC2ENSG00000005436.91175.75830894.898900.393704.825904.24530HepG2SRSF1
GCFC2ENSG00000005436.9678.56640832.53910-0.295002.704402.08360HepG2SRSF5
GCFC2ENSG00000005436.9374.10470554.51350-0.567805.678304.73860HepG2SRSF7
GCFC2ENSG00000005436.9532.59480728.05700-0.451004.958104.25880HepG2SRSF9
GCFC2ENSG00000005436.91246.50810935.005700.414705.730605.04390HepG2SSB
GCFC2ENSG00000005436.91056.14960804.399200.392704.033803.37680HepG2TAF15
GCFC2ENSG00000005436.9245.08500369.84730-0.593602.405001.46780HepG2TFIP11
GCFC2ENSG00000005436.9308.50150622.92500-1.013802.893101.88160HepG2U2AF2
GCFC2ENSG00000005436.9765.74330462.015500.728805.187803.67750HepG2XPO5
GCFC2ENSG00000005436.9978.13770603.174600.697404.673503.02210HepG2XRCC5
GCFC2ENSG00000005436.9943.01500674.735000.482902.303601.33890HepG2XRCC6
GCFC2ENSG00000005436.9428.58790530.93460-0.308902.202701.59310HepG2ZC3H8
GCFC2ENSG00000005436.9588.09520726.66350-0.305202.818302.26800HepG2ZNF622
GCFC2ENSG00000005436.9488.15220356.044400.455202.680101.51950K562AARS
GCFC2ENSG00000005436.9548.34030853.91630-0.639005.648004.86040K562AQR
GCFC2ENSG00000005436.9337.58340479.39470-0.506003.926302.30840K562BCCIP
GCFC2ENSG00000005436.9321.48710463.26590-0.527104.347403.12750K562BCLAF1
GCFC2ENSG00000005436.91242.70170709.646000.8082017.5408016.02350K562DDX47
GCFC2ENSG00000005436.9229.97870389.13280-0.758805.316304.02750K562EFTUD2
GCFC2ENSG00000005436.9279.01560381.43800-0.451103.212101.89700K562EIF2S1
GCFC2ENSG00000005436.9371.02830562.29920-0.599805.978204.98100K562EIF2S2
GCFC2ENSG00000005436.9496.88010338.300000.554503.430902.15930K562FKBP4
GCFC2ENSG00000005436.9320.97790455.09570-0.503703.046402.14490K562FMR1
GCFC2ENSG00000005436.9245.48020385.74990-0.652104.024102.90680K562FTO
GCFC2ENSG00000005436.9296.72150417.70520-0.493403.233201.77490K562FUS
GCFC2ENSG00000005436.9479.00130377.325700.344102.072801.53480K562FXR1
GCFC2ENSG00000005436.9578.41920384.556000.588803.480302.66870K562G3BP2
GCFC2ENSG00000005436.9273.06690426.99390-0.645003.306402.44030K562GPKOW
GCFC2ENSG00000005436.9220.01960389.48050-0.823906.386905.51660K562HNRNPC
GCFC2ENSG00000005436.9381.82830552.78980-0.533804.766503.58580K562HNRNPU
GCFC2ENSG00000005436.9367.14260516.80100-0.493302.615901.62790K562IGF2BP2
GCFC2ENSG00000005436.9270.77520395.11890-0.545203.181901.59020K562LIN28B
GCFC2ENSG00000005436.9285.69880416.79980-0.544903.548702.54960K562METAP2
GCFC2ENSG00000005436.9405.28480530.97530-0.389703.083802.29980K562NSUN2
GCFC2ENSG00000005436.9567.341001025.84520-0.8545010.618709.00850K562PUF60
GCFC2ENSG00000005436.91334.566401091.101400.290502.442501.44440K562PUM1
GCFC2ENSG00000005436.9635.91140461.589900.462102.919002.36410K562PUS1
GCFC2ENSG00000005436.9248.70260364.83110-0.552803.346901.86620K562RBM25
GCFC2ENSG00000005436.9643.93520385.748200.739205.870204.67570K562RPS19
GCFC2ENSG00000005436.9354.96900212.244000.741903.990902.76040K562RPS3
GCFC2ENSG00000005436.9347.66530488.70940-0.491303.175802.03700K562SRSF5
GCFC2ENSG00000005436.9286.97510411.62100-0.520404.007902.57710K562SRSF7
GCFC2ENSG00000005436.9451.40960334.333700.433002.824601.99590K562SYNCRIP
GCFC2ENSG00000005436.9351.06830523.88660-0.577503.276502.50510K562TARDBP
GCFC2ENSG00000005436.9206.04540334.22710-0.697904.226302.17250K562TFIP11
GCFC2ENSG00000005436.9330.29190505.32720-0.613504.112803.08590K562TIA1
GCFC2ENSG00000005436.9211.18910335.88650-0.669403.724702.63660K562TIAL1
GCFC2ENSG00000005436.9261.34320356.90420-0.449602.230601.39450K562TRIM56
GCFC2ENSG00000005436.9418.76130563.00880-0.427003.096802.33850K562UPF1
GCFC2ENSG00000005436.9613.62270501.005700.292402.318901.53860K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GCFC2 is not available on ENCORE database.





17 RBPs can affect the splicing of GCFC2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGCFC2ENSG00000005436.9chr2-7591910275919226759177237591784575921366759215530.246000.000340.00873includedK562SRSF1
SEGCFC2ENSG00000005436.9chr2-7591910275919226759177197591784575921366759215530.308000.002190.03913includedK562SF3B4
SEGCFC2ENSG00000005436.9chr2-759191027591922675917763759178457592136675921553-0.212000.002030.03692excludedHepG2U2AF1
SEGCFC2ENSG00000005436.9chr2-7592943875929573759283157592841375933648759337770.458000.002310.05938includedK562AKAP8L
SEGCFC2ENSG00000005436.9chr2-759191027591922675917719759178457592136675921553-0.235000.003540.03500excludedK562AQR
SEGCFC2ENSG00000005436.9chr2-7591910275919226759177637591784575921366759215530.275000.001650.05828includedK562FXR1
SEGCFC2ENSG00000005436.9chr2-7592940575929573759283157592841375933648759337770.433000.006100.07236includedK562PUS1
SEGCFC2ENSG00000005436.9chr2-759073187590744075899075758991427591495275915103-0.174000.004960.06187excludedK562PUS1
SEGCFC2ENSG00000005436.9chr2-759191027591922675917719759178457592136675921553-0.211000.004800.06035excludedK562PUS1
SEGCFC2ENSG00000005436.9chr2-759294057592957375928315759284137593364875933777-0.553000.001860.07149excludedHepG2SFPQ
SEGCFC2ENSG00000005436.9chr2-759191027591922675917719759178457592136675921553-0.239000.003480.06170excludedK562U2AF1
SEGCFC2ENSG00000005436.9chr2-7591910275919226759177197591784575921366759215530.185000.000110.01195includedK562HNRNPL
SEGCFC2ENSG00000005436.9chr2-759294387592957375928315759284137593364875933777-0.845000.000040.01020excludedHepG2RBFOX2
SEGCFC2ENSG00000005436.9chr2-7592943875929549759283157592841375933648759337770.208000.003850.07632includedK562AGGF1
SEGCFC2ENSG00000005436.9chr2-7591910275919226759177197591784575921366759215530.366000.000030.04594includedK562QKI
SEGCFC2ENSG00000005436.9chr2-7592943875929549759283157592841375933648759337770.251000.001830.07092includedK562HNRNPK
SEGCFC2ENSG00000005436.9chr2-7591910275919226759177237591784575921366759215530.151000.000260.04883includedK562EIF3G
SEGCFC2ENSG00000005436.9chr2-7591910275919226759177197591784575921366759215530.240000.000430.02074includedK562PTBP1
A3SSGCFC2ENSG00000005436.9chr2-7592940575929573759294057592954975933648759337770.117000.000260.02502longerHepG2SF3A3
A3SSGCFC2ENSG00000005436.9chr2-7592940575929573759294057592954975933648759337770.372000.000000.00006longerK562U2AF2
A3SSGCFC2ENSG00000005436.9chr2-7591615175916370759161517591635175917094759172070.080000.002380.01501longerK562AQR
A3SSGCFC2ENSG00000005436.9chr2-7589305475893199758930547589317975897263758974100.081000.007780.04256longerK562AQR
A3SSGCFC2ENSG00000005436.9chr2-7592943875929573759294387592954975933648759337770.215000.000560.00412longerK562AQR
A3SSGCFC2ENSG00000005436.9chr2-7592932475929573759293247592954975933648759337770.180000.000000.00011longerHepG2U2AF1
A3SSGCFC2ENSG00000005436.9chr2-7592940575929573759294057592954975933648759337770.344000.000030.00286longerK562U2AF1
A3SSGCFC2ENSG00000005436.9chr2-759293247592957375929324759295497593364875933777-0.196000.000030.04981shorterHepG2RBFOX2
MXEGCFC2ENSG00000005436.9chr2-75917719759178457591910275919226759170947591720775921366759215530.272000.004240.095341includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GCFC2 is not avaliable on ENCORE database.