VPS41

General Information

Gene Name       : VPS41
Gene ID             : ENSG00000006715.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: VPS41)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878VPS41ENSG00000006715.1534.5232.6333.58ENCSR000AEF
HepG2VPS41ENSG00000006715.1513.6421.7617.70ENCSR985KAT
K562VPS41ENSG00000006715.1527.9121.6224.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for VPS41 is not avaliable on ENCORE database.



Proteins bound to RNA
  • VPS41 RNA is bound by 15 proteins.  







eCLIP assay for VPS41 is not avaliable on ENCORE database.





15 proteins are bound to VPS41 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr73883518138835211-3'-UTR,CDS,intron-Distal3.337624.56058HepG2BCLAF1
chr73883510938835212-3'-UTR,CDS,intron-Distal,intron-Proximal3.173906.07808K562UCHL5
chr73883518938835260-3'-UTR,CDS,intron-Distal,intron-Proximal5.244453.91589K562SF3B4
chr73890880738908854-3'-UTR,CDS,intron-Distal,intron-Proximal3.3518812.56268K562ZNF622
chr73890874438908807-3'-UTR,CDS,intron-Distal,intron-Proximal3.745189.12722K562ZNF622
chr73890877138908854-3'-UTR,CDS,intron-Distal,intron-Proximal4.721846.45870K562GRWD1
chr73890881138908853-3'-UTR,CDS,intron-Distal3.275546.92192K562UCHL5
chr73883513138835185-3'-UTR,CDS,intron-Distal,intron-Proximal5.068367.69747K562ZNF622
chr73890875338908811-3'-UTR,CDS,intron-Distal4.720584.78571K562UCHL5
chr73883518538835212-3'-UTR,CDS,intron-Distal,intron-Proximal4.673814.55944K562ZNF622
chr73876444638764529-3'-UTR,intron-Distal4.412088.55060HepG2UPF1
chr73893768938937728-5'-UTR,CDS,intron-Distal,intron-Proximal3.759588.33890K562UCHL5
chr73893769038937728-5'-UTR,CDS,intron-Distal,intron-Proximal4.111823.80193HepG2GRWD1
chr73880713538807195-CDS,intron-Distal,intron-Proximal4.344553.59941K562UCHL5
chr73878515838785261-CDS,intron-Distal,intron-Proximal3.934475.93727K562SF3B4
chr73879430238794334-CDS,intron-Distal3.123453.01994K562BUD13
chr73883505938835094-CDS,intron-Distal,intron-Proximal4.274444.12139K562DDX24
chr73879804838798082-CDS,intron-Distal,intron-Proximal4.805355.37137HepG2BCLAF1
chr73890214438902171-CDS,intron-Distal,intron-Proximal3.881553.01428K562UCHL5
chr73883503338835090-CDS,intron-Distal,intron-Proximal3.799797.56654HepG2PRPF8
chr73878300938783072-CDS,intron-Distal4.229327.82678K562ZNF622
chr73886084538860922-CDS,intron-Distal,intron-Proximal4.270688.28159K562SF3B4
chr73883506338835090-CDS,intron-Distal,intron-Proximal3.521033.73423K562UCHL5
chr73879655238796581-CDS,intron-Distal4.491344.34038HepG2BCLAF1
chr73883633738836398-CDS,intron-Distal,intron-Proximal3.4378012.17213K562DDX24
chr73883634138836451-CDS,intron-Distal,intron-Proximal4.2367814.01444HepG2BCLAF1
chr73876834638768382-CDS,intron-Distal3.291073.27569HepG2BCLAF1
chr73880308838803147-CDS,intron-Distal3.813177.28307HepG2BCLAF1
chr73881372238813846-CDS,intron-Distal,intron-Proximal3.178546.12266HepG2BCLAF1
chr73879804238798081-CDS,intron-Distal3.248653.02345K562ZNF622
chr73879804638798080-CDS,intron-Distal3.267143.17151K562UCHL5
chr73883637438836477-CDS,intron-Distal,intron-Proximal3.925403.95991K562U2AF2
chr73878310238783159-CDS,intron-Distal,intron-Proximal4.194613.95991K562U2AF2
chr73881627638816375-CDS,intron-Distal,intron-Proximal4.179757.34123K562DDX24
chr73885733738857429-CDS,intron-Distal,intron-Proximal3.152834.64757K562KHSRP
chr73886984338869918-CDS,intron-Distal,intron-Proximal4.633769.88142K562ZNF622
chr73879186338791892-CDS,intron-Distal3.422593.27569HepG2BCLAF1
chr73883633938836455-CDS,intron-Distal,intron-Proximal3.368618.83000K562UCHL5
chr73885741538857480-CDS,intron-Distal,intron-Proximal4.301817.97334HepG2BCLAF1
chr73890214238902162-CDS,intron-Distal,intron-Proximal5.600484.75872K562DDX24
chr73890216238902213-CDS,intron-Distal4.774445.79396K562DDX24
chr73890214438902202-CDS,intron-Distal,intron-Proximal5.395028.86847HepG2BCLAF1
chr73883506738835131-CDS,intron-Distal,intron-Proximal3.333625.66840K562ZNF622
chr73878159138781626-CDS,intron-Distal4.480334.37348HepG2BCLAF1
chr73886080738860859-CDS,intron-Distal,intron-Proximal3.564425.56491HepG2BCLAF1
chr73883639838836465-CDS,intron-Distal,intron-Proximal4.0602717.97049K562DDX24
chr73886985838869925-CDS,intron-Distal4.100487.88406K562DDX24
chr73878300238783021-CDS,intron-Distal4.372824.04372HepG2BCLAF1
chr73890217338902223-CDS,intron-Distal,intron-Proximal3.755565.08507K562ZNF622
chr73886985538869924-CDS,intron-Distal3.603328.25092HepG2BCLAF1
chr73886985338869924-CDS,intron-Distal,intron-Proximal3.013064.02759K562UCHL5
chr73879176938791847-CDS,intron-Distal,intron-Proximal3.372794.27261HepG2GRWD1
chr73880311938803143-CDS,intron-Distal3.778323.01428K562UCHL5
chr73880517938805199-CDS,intron-Distal,intron-Proximal3.593114.09885HepG2BCLAF1
chr73881627838816309-CDS,intron-Distal,intron-Proximal3.381363.27569HepG2BCLAF1
chr73878304938783130-CDS,intron-Distal4.859824.37348HepG2BCLAF1
chr73879430338794351-CDS,intron-Distal3.750407.28307HepG2BCLAF1
chr73879168138791730-intron-Distal,intron-Proximal4.8281910.40891K562PRPF8
chr73877499138775160-intron-Distal4.9788913.45737K562HNRNPL
chr73883485338834989-intron-Distal,intron-Proximal3.073485.03031K562KHSRP
chr73879421138794272-intron-Distal,intron-Proximal5.8416812.16286K562RBM22
chr73878592838786030-intron-Distal4.9391613.79808K562QKI
chr73877497138775167-intron-Distal4.2004615.13504K562AGGF1
chr73878593038786021-intron-Distal4.4410112.51709HepG2QKI
chr73877504538775115-intron-Distal4.5673210.49938HepG2HNRNPL
chr73877511538775172-intron-Distal3.8973310.37585HepG2HNRNPL
chr73883710038837260-intron-Distal3.663364.08064K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for VPS41 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for VPS41 is not available on ENCORE database.

  • 58 RBPs can affect the levels of VPS41.  








The Knockdown/knockout RNA-Seq assay for VPS41 is not available on ENCORE database.





58 RBPs can affect the gene expression of VPS41 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
VPS41ENSG00000006715.11638.03140841.02180-0.398504.503403.76400HepG2ACO1
VPS41ENSG00000006715.111088.43960869.178300.324402.039601.36960HepG2CIRBP
VPS41ENSG00000006715.111115.06060840.853400.407105.846704.94460HepG2CKAP4
VPS41ENSG00000006715.11842.90290553.543700.606602.487201.76620HepG2CNOT7
VPS41ENSG00000006715.11535.02130704.55350-0.397102.465001.50790HepG2YBX3
VPS41ENSG00000006715.11790.67630999.78450-0.338503.351102.65720HepG2CELF1
VPS41ENSG00000006715.11540.31420909.80820-0.751806.443005.53050HepG2DDX6
VPS41ENSG00000006715.11535.15090691.83160-0.370503.080402.34220HepG2DNAJC21
VPS41ENSG00000006715.11514.16680685.70380-0.415304.516203.71840HepG2DNAJC2
VPS41ENSG00000006715.11510.76680941.10570-0.881707.227306.14530HepG2EIF4B
VPS41ENSG00000006715.11762.410501015.97480-0.414203.230602.35430HepG2EIF4G2
VPS41ENSG00000006715.111012.31440821.841300.300602.174201.43440HepG2EWSR1
VPS41ENSG00000006715.111071.92010812.799900.399102.222301.52820HepG2FIP1L1
VPS41ENSG00000006715.11738.49380493.876000.580305.147004.08520HepG2FUBP3
VPS41ENSG00000006715.111193.94990776.900700.619806.840405.78860HepG2HNRNPC
VPS41ENSG00000006715.11764.59490979.34100-0.357104.397103.56210HepG2HNRNPL
VPS41ENSG00000006715.11568.19670788.33320-0.472406.599505.51450HepG2ILF2
VPS41ENSG00000006715.11555.02430688.35360-0.310602.311201.63050HepG2PPIL4
VPS41ENSG00000006715.11758.91950620.802700.289702.346901.62780HepG2PRPF4
VPS41ENSG00000006715.11795.88480555.957200.517503.846702.91380HepG2PRPF8
VPS41ENSG00000006715.11809.627001017.61620-0.329902.490001.92030HepG2PUF60
VPS41ENSG00000006715.111135.10280933.102700.282602.225601.65490HepG2QKI
VPS41ENSG00000006715.11509.75380812.57940-0.672703.344602.57240HepG2RAVER1
VPS41ENSG00000006715.11679.42040942.31310-0.471904.779703.69070HepG2RBM15
VPS41ENSG00000006715.111674.254801094.629000.6130011.1445010.25600HepG2RBM22
VPS41ENSG00000006715.11818.53640549.963900.573604.213203.26460HepG2RRP9
VPS41ENSG00000006715.11451.61550687.29430-0.605807.869106.86530HepG2SAFB2
VPS41ENSG00000006715.11986.19690753.275200.388602.901902.17890HepG2SF3B1
VPS41ENSG00000006715.11614.46480838.14240-0.447902.048901.38080HepG2SNRNP70
VPS41ENSG00000006715.111019.308001236.35530-0.278503.022902.50650HepG2SRFBP1
VPS41ENSG00000006715.111132.33320936.268800.274202.582402.12140HepG2SRSF1
VPS41ENSG00000006715.11500.84700810.46090-0.694405.193103.78210HepG2SRSF3
VPS41ENSG00000006715.11441.90130749.93690-0.763009.794708.95600HepG2TIAL1
VPS41ENSG00000006715.11634.71570756.61580-0.253501.957801.46750HepG2TRIM56
VPS41ENSG00000006715.11878.43460695.297700.337201.994201.45160HepG2U2AF1
VPS41ENSG00000006715.11575.57110809.31050-0.491705.504904.70840HepG2UTP3
VPS41ENSG00000006715.11531.00720706.16840-0.411302.185601.53490HepG2XRN2
VPS41ENSG00000006715.11738.19550612.646800.268802.180101.57350HepG2ZC3H8
VPS41ENSG00000006715.111104.84900921.928800.261002.861102.30770HepG2ZNF622
VPS41ENSG00000006715.11988.823401191.21060-0.268601.847401.30880K562AKAP8L
VPS41ENSG00000006715.111096.311901587.79560-0.534405.586604.80320K562AQR
VPS41ENSG00000006715.11650.85690867.01190-0.413703.487602.30170K562DDX3X
VPS41ENSG00000006715.111091.707401281.94810-0.231802.048901.30650K562DKC1
VPS41ENSG00000006715.11701.67640937.35850-0.417804.213803.23990K562EIF3G
VPS41ENSG00000006715.11637.49360905.80870-0.506804.584003.52820K562EIF4A3
VPS41ENSG00000006715.11540.38860815.72540-0.594107.326705.31090K562EIF4B
VPS41ENSG00000006715.111111.920701649.03190-0.568604.306103.36680K562GRSF1
VPS41ENSG00000006715.11602.79020885.01060-0.554004.187203.02580K562HNRNPM
VPS41ENSG00000006715.11908.792801123.54470-0.306002.685201.80600K562HNRNPU
VPS41ENSG00000006715.111128.647501458.88840-0.370303.083402.24580K562HSPD1
VPS41ENSG00000006715.11843.012401213.41140-0.525406.069904.62950K562MATR3
VPS41ENSG00000006715.11642.03920831.26810-0.372702.755701.88060K562METAP2
VPS41ENSG00000006715.111480.241601081.832600.452304.420503.17580K562PCBP2
VPS41ENSG00000006715.111213.63460894.548000.440002.959302.09890K562PCBP3
VPS41ENSG00000006715.11924.83410686.181500.430504.040103.06690K562POLR2G
VPS41ENSG00000006715.11890.089301221.45070-0.456604.123003.09550K562PPIG
VPS41ENSG00000006715.11866.009801132.74320-0.387403.127902.22870K562RBM22
VPS41ENSG00000006715.11817.936901300.89730-0.669402.659801.39210K562SFPQ
VPS41ENSG00000006715.11449.81410599.04440-0.413302.595001.61230K562SRFBP1
VPS41ENSG00000006715.11894.839301158.05360-0.372003.260902.49730K562SRSF1
VPS41ENSG00000006715.11872.861101093.68110-0.325402.266301.33380K562SRSF5
VPS41ENSG00000006715.11876.779801130.55940-0.366803.179902.29450K562TIA1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for VPS41 is not available on ENCORE database.





10 RBPs can affect the splicing of VPS41 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEVPS41ENSG00000006715.11chr7-3885765738857753388574163885748238860802388608650.220000.000010.00055includedK562SRSF1
SEVPS41ENSG00000006715.11chr7-387679403876803438766508387665883876814138768186-0.090000.000120.01214excludedHepG2RBM22
SEVPS41ENSG00000006715.11chr7-3876794038768034387665083876658838768141387682050.326000.000000.00000includedK562AKAP8L
SEVPS41ENSG00000006715.11chr7-388360143883612638835141388352113883634438836464-0.200000.000060.00340excludedK562AKAP8L
SEVPS41ENSG00000006715.11chr7-3876794038768034387665083876658838768141387681860.118000.000860.01078includedK562AQR
SEVPS41ENSG00000006715.11chr7-3883601438836126388351413883521138836344388364640.092000.001230.01454includedK562AQR
SEVPS41ENSG00000006715.11chr7-387679403876803438766508387665883876814138768186-0.169000.002050.06797excludedK562FXR1
SEVPS41ENSG00000006715.11chr7-3876794038768034387665083876658838768141387681860.178000.004130.05381includedK562PUS1
SEVPS41ENSG00000006715.11chr7-387679403876803438766508387665883876814138768186-0.090000.000900.04725excludedHepG2PTBP1
SEVPS41ENSG00000006715.11chr7-3876794038768034387665083876658838768141387681860.183000.000340.01188includedK562AGGF1
SEVPS41ENSG00000006715.11chr7-3876794038768034387665083876658838768141387682050.177000.000000.00017includedK562ZC3H8
SEVPS41ENSG00000006715.11chr7-3883601438836126388351413883521138836344388364640.132000.000000.00167includedK562ZC3H8
SEVPS41ENSG00000006715.11chr7-387679403876803438766508387665883876814138768186-0.170000.000000.00014excludedK562PTBP1
A3SSVPS41ENSG00000006715.11chr7-3876650838766657387665083876658838768141387682050.093000.000170.00143longerK562AQR
A3SSVPS41ENSG00000006715.11chr7-3881212138812271388121213881223738813714388138440.077000.002380.01503longerK562AQR
A3SSVPS41ENSG00000006715.11chr7-3879172038791965387917203879191338794301387943520.062000.004300.02533longerK562AQR
MXEVPS41ENSG00000006715.11chr7-38869853388699283890214438902222388608023886086538908745389088530.214000.000060.008391includedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for VPS41 is not avaliable on ENCORE database.