FBXL3

General Information

Gene Name       : FBXL3
Gene ID             : ENSG00000005812.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXL3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXL3ENSG00000005812.1015.9312.8014.37ENCSR000AEF
HepG2FBXL3ENSG00000005812.106.9712.489.72ENCSR985KAT
K562FBXL3ENSG00000005812.106.967.457.21ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXL3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXL3 RNA is bound by 11 proteins.  







eCLIP assay for FBXL3 is not avaliable on ENCORE database.





11 proteins are bound to FBXL3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr137759591777596037-5'-UTR,CDS,intron-Distal,intron-Proximal4.422564.59919HepG2AQR
chr137760113877601252-5'-UTR,intron-Distal,intron-Proximal3.933243.16390K562SRSF1
chr137759573877595794-CDS,intron-Distal,intron-Proximal4.428595.14756K562RBM15
chr137759273277592794-CDS,intron-Distal,intron-Proximal3.872703.66655K562YBX3
chr137759579477595851-CDS,intron-Distal4.433924.82934K562RBM15
chr137760080277600862-intron-Distal3.571064.13948HepG2PRPF4
chr137760080477600862-intron-Distal4.694426.51015K562CSTF2T
chr137760036977600427-intron-Distal5.148794.75034HepG2XPO5
chr137760078977600860-intron-Distal4.458406.40957HepG2EFTUD2
chr137760079377600858-intron-Distal4.679905.84281K562GTF2F1
chr137760078777600858-intron-Distal4.374673.34123HepG2FKBP4
chr137759721277597305-intron-Distal4.597136.02873K562TARDBP
chr137760078077600863-intron-Distal4.116313.63902HepG2CSTF2T
chr137760080077600859-intron-Distal3.866603.29554HepG2GTF2F1
chr137760066277600714-intron-Distal4.315503.18269HepG2XPO5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXL3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXL3 is not available on ENCORE database.

  • 71 RBPs can affect the levels of FBXL3.  








The Knockdown/knockout RNA-Seq assay for FBXL3 is not available on ENCORE database.





71 RBPs can affect the gene expression of FBXL3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXL3ENSG00000005812.6188.49300336.21470-0.834905.981304.46600HepG2AATF
FBXL3ENSG00000005812.6342.22790674.67380-0.979203.637802.96240HepG2BOP1
FBXL3ENSG00000005812.6523.55510809.77470-0.629203.533202.41760HepG2CCAR1
FBXL3ENSG00000005812.6350.76590486.01370-0.470504.165803.38220HepG2CKAP4
FBXL3ENSG00000005812.6252.07580371.29800-0.558702.888902.19710HepG2DDX21
FBXL3ENSG00000005812.6210.51540382.49880-0.861503.995703.24090HepG2DNAJC2
FBXL3ENSG00000005812.61261.16270747.263200.7550015.1315013.90710HepG2ETF1
FBXL3ENSG00000005812.6313.92550518.91340-0.725104.410803.02020HepG2FUS
FBXL3ENSG00000005812.6531.85050694.32050-0.384602.222201.42860HepG2G3BP2
FBXL3ENSG00000005812.6380.25850538.41600-0.501702.375201.34240HepG2GRSF1
FBXL3ENSG00000005812.6279.47840480.27660-0.781105.359203.36800HepG2HNRNPAB
FBXL3ENSG00000005812.6421.84520668.60880-0.664404.343003.05890HepG2KHSRP
FBXL3ENSG00000005812.6501.26420709.18560-0.500603.050402.39130HepG2MATR3
FBXL3ENSG00000005812.6498.27040725.87550-0.542803.728202.99740HepG2NCBP2
FBXL3ENSG00000005812.6300.76670426.23320-0.503002.264601.49130HepG2PARN
FBXL3ENSG00000005812.6478.30530636.00520-0.411103.769703.08460HepG2PCBP1
FBXL3ENSG00000005812.6464.56810647.13740-0.478204.431403.77410HepG2PTBP1
FBXL3ENSG00000005812.6368.90580495.09050-0.424403.495202.82120HepG2PUS1
FBXL3ENSG00000005812.6542.33880700.91200-0.370002.835402.20450HepG2QKI
FBXL3ENSG00000005812.6847.72130474.057500.838405.070304.12970HepG2RAVER1
FBXL3ENSG00000005812.6805.72020636.105200.340902.310501.68900HepG2RBM25
FBXL3ENSG00000005812.6522.95710670.75430-0.359102.972602.33650HepG2RECQL
FBXL3ENSG00000005812.6730.18830486.958400.584404.828903.95960HepG2RPLP0
FBXL3ENSG00000005812.6314.25490465.65300-0.567302.668901.73980HepG2RPS10
FBXL3ENSG00000005812.6452.94080332.719000.444902.290001.56810HepG2RRP9
FBXL3ENSG00000005812.6221.63960383.46310-0.790904.040003.28670HepG2SAFB2
FBXL3ENSG00000005812.6361.93600554.81650-0.616303.103901.45630HepG2SBDS
FBXL3ENSG00000005812.6712.24920538.704000.402802.000401.42520HepG2SF3A3
FBXL3ENSG00000005812.61042.87970738.115100.498602.678701.90960HepG2SNRNP70
FBXL3ENSG00000005812.61180.40390705.443500.7426015.9340014.99210HepG2SRFBP1
FBXL3ENSG00000005812.6820.37850612.503100.421504.722404.08800HepG2SSB
FBXL3ENSG00000005812.6699.08440443.015700.658003.688602.29090HepG2SUB1
FBXL3ENSG00000005812.6488.66830689.45070-0.496604.841004.05910HepG2SUCLG1
FBXL3ENSG00000005812.6450.05350580.85070-0.368102.535801.73310HepG2TIA1
FBXL3ENSG00000005812.6286.07630418.50030-0.548802.218501.76080HepG2TIAL1
FBXL3ENSG00000005812.6257.70550475.98840-0.885205.625803.57070HepG2TRA2A
FBXL3ENSG00000005812.6258.77100422.11480-0.706002.903202.32890HepG2TRIM56
FBXL3ENSG00000005812.6997.96370538.779300.8892011.3543010.05840HepG2U2AF1
FBXL3ENSG00000005812.6318.40650477.74700-0.585405.509504.57610HepG2UPF1
FBXL3ENSG00000005812.6288.08080427.15990-0.568302.743802.02150HepG2XRN2
FBXL3ENSG00000005812.6536.66560341.878400.650404.723803.88460HepG2ZC3H8
FBXL3ENSG00000005812.6719.50520525.431800.453405.352204.65420HepG2ZNF622
FBXL3ENSG00000005812.6553.79080350.323100.660606.960506.11930K562AGGF1
FBXL3ENSG00000005812.6572.85070364.527000.652005.643104.69190K562AKAP8L
FBXL3ENSG00000005812.6889.99720571.695000.638505.737704.94610K562AQR
FBXL3ENSG00000005812.61021.97550692.265300.561906.777105.26940K562CELF1
FBXL3ENSG00000005812.6723.94700467.426900.631008.243207.19720K562DDX47
FBXL3ENSG00000005812.6255.59690128.580200.991102.661801.67970K562EIF3A
FBXL3ENSG00000005812.6409.87770297.458100.462403.139402.29360K562EIF3G
FBXL3ENSG00000005812.6923.84540563.121500.7141010.752808.95430K562EIF4G2
FBXL3ENSG00000005812.6322.46970222.881200.532802.610001.52150K562FKBP4
FBXL3ENSG00000005812.6570.85830295.461700.950103.676402.83560K562G3BP2
FBXL3ENSG00000005812.6438.31230306.052300.518103.870902.52870K562GLRX3
FBXL3ENSG00000005812.6458.53240313.697500.547502.822501.73960K562HNRNPA1
FBXL3ENSG00000005812.6796.71360517.365900.622803.050901.55050K562ILF2
FBXL3ENSG00000005812.6582.06620386.854800.589303.808002.81790K562KIF1C
FBXL3ENSG00000005812.6899.05350600.253400.582705.459503.87580K562MSI2
FBXL3ENSG00000005812.6422.05530321.772300.391302.470801.70560K562MTPAP
FBXL3ENSG00000005812.6549.34890303.764400.854702.603901.75350K562NAA15
FBXL3ENSG00000005812.6902.15620615.908900.550605.256603.15170K562NOL12
FBXL3ENSG00000005812.6491.87770329.141300.579503.458002.52630K562PCBP3
FBXL3ENSG00000005812.6369.20050252.450100.548303.394902.50080K562POLR2G
FBXL3ENSG00000005812.6384.50160271.233900.503402.725301.98160K562PRPF8
FBXL3ENSG00000005812.6286.22260394.97010-0.464602.903402.22560K562PTBP1
FBXL3ENSG00000005812.6916.93170614.425700.577505.706504.53920K562PUF60
FBXL3ENSG00000005812.6955.93870653.413000.548806.474304.78380K562PUM1
FBXL3ENSG00000005812.6830.17920640.343100.374503.624402.52540K562PUM2
FBXL3ENSG00000005812.61017.87040361.511901.4933026.9385025.23700K562PUS1
FBXL3ENSG00000005812.6643.36540352.237900.8690011.3633010.18070K562RBM15
FBXL3ENSG00000005812.6412.24770277.400200.571402.912001.55060K562RRP9
FBXL3ENSG00000005812.6476.61610361.423400.399002.901701.94700K562SRPK2
FBXL3ENSG00000005812.6257.37400353.61650-0.458302.284501.34520K562SRSF4
FBXL3ENSG00000005812.6251.91350378.02080-0.585502.672101.86960K562TIA1
FBXL3ENSG00000005812.6268.30320370.81780-0.466802.549701.50920K562TRA2A
FBXL3ENSG00000005812.6457.86000286.370700.676904.441702.98990K562U2AF1
FBXL3ENSG00000005812.6434.18810295.767600.553804.163303.18070K562U2AF2
FBXL3ENSG00000005812.6431.52770324.379500.411702.434301.61120K562WDR3
FBXL3ENSG00000005812.6475.86910337.308400.496404.377303.33070K562WDR43
FBXL3ENSG00000005812.6953.58270644.007100.566205.782204.46100K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXL3 is not available on ENCORE database.





1 RBPs can affect the splicing of FBXL3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXL3ENSG00000005812.6chr13-775956477759599677592734775928577760096177601285-0.280000.001580.03903excludedHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXL3 is not avaliable on ENCORE database.