SERPINB1

General Information

Gene Name       : SERPINB1
Gene ID             : ENSG00000021355.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SERPINB1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SERPINB1ENSG00000021355.122.040.751.40ENCSR000AEF
HepG2SERPINB1ENSG00000021355.1217.6729.6123.64ENCSR985KAT
K562SERPINB1ENSG00000021355.1241.6552.6447.14ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SERPINB1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SERPINB1 RNA is bound by 10 proteins.  







eCLIP assay for SERPINB1 is not avaliable on ENCORE database.





10 proteins are bound to SERPINB1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr628331142833216-3'-UTR,intron-Distal4.253853.43975HepG2LIN28B
chr628331822833240-3'-UTR,intron-Distal5.885067.00172K562PUM2
chr628331502833226-3'-UTR,intron-Distal5.221879.44026K562LIN28B
chr628334362833514-3'-UTR,intron-Distal4.464684.55369K562LIN28B
chr628408172840890-5'-UTR,CDS,intron-Distal,intron-Proximal4.340284.82767HepG2SF3B4
chr628381162838228-5'-UTR,CDS,intron-Distal3.201977.90382HepG2BCLAF1
chr628420432842134-5'-UTR,intron-Distal,intron-Proximal4.924635.07098K562DDX3X
chr628388872838913-5'-UTR,CDS,intron-Distal3.945373.01531K562YBX3
chr628407202840759-5'-UTR,CDS,intron-Distal,intron-Proximal3.187547.65028K562YBX3
chr628420032842063-5'-UTR,intron-Distal4.425213.93614HepG2AQR
chr628381292838219-5'-UTR,CDS,intron-Distal3.172165.51805K562YBX3
chr628406982840715-5'-UTR,CDS,intron-Distal3.018718.74579K562YBX3
chr628406812840829-5'-UTR,CDS,intron-Distal,intron-Proximal3.009317.37025K562DDX3X
chr628341402834247-CDS,intron-Distal3.8358211.95754HepG2BCLAF1
chr628363382836380-CDS,intron-Distal,intron-Proximal3.498595.97823HepG2BCLAF1
chr628362352836258-CDS,intron-Distal,intron-Proximal3.554104.09885HepG2BCLAF1
chr628361402836228-CDS,intron-Distal3.172227.33264HepG2GRWD1
chr628344442834601-intron-Distal4.325078.76214K562EIF4G2
chr628346002834748-intron-Distal4.605483.99130HepG2FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SERPINB1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SERPINB1 is not available on ENCORE database.

  • 110 RBPs can affect the levels of SERPINB1.  








The Knockdown/knockout RNA-Seq assay for SERPINB1 is not available on ENCORE database.





110 RBPs can affect the gene expression of SERPINB1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SERPINB1ENSG00000021355.81686.918501331.863700.340802.851301.76570HepG2AATF
SERPINB1ENSG00000021355.82073.320001457.921200.507908.051707.12430HepG2ACO1
SERPINB1ENSG00000021355.82430.754803328.20230-0.453303.580502.98570HepG2AKAP1
SERPINB1ENSG00000021355.82433.508501464.651400.7324018.4033016.66800HepG2AKAP8L
SERPINB1ENSG00000021355.81434.446901070.662400.421902.202501.40000HepG2BCLAF1
SERPINB1ENSG00000021355.81239.419801457.46060-0.233802.707502.04770HepG2CKAP4
SERPINB1ENSG00000021355.81931.848001230.387800.6508010.078508.12530HepG2CPSF7
SERPINB1ENSG00000021355.82658.229402042.065200.380305.936305.06180HepG2CELF1
SERPINB1ENSG00000021355.81784.002302195.86440-0.299703.991803.12730HepG2DAZAP1
SERPINB1ENSG00000021355.81856.516001133.514700.711707.399605.40260HepG2DDX27
SERPINB1ENSG00000021355.82294.901403188.22890-0.474304.438303.65990HepG2DDX3X
SERPINB1ENSG00000021355.82179.800201211.245500.847608.008306.77150HepG2DDX55
SERPINB1ENSG00000021355.82049.251102738.60660-0.418303.174602.51780HepG2DDX6
SERPINB1ENSG00000021355.81574.352601250.926600.331703.821303.00540HepG2DNAJC21
SERPINB1ENSG00000021355.83460.966102632.835800.394503.331502.68530HepG2EIF2S1
SERPINB1ENSG00000021355.81041.946801387.62370-0.413304.340103.02350HepG2EIF3G
SERPINB1ENSG00000021355.81702.316602909.66410-0.773409.079607.92850HepG2EIF4A3
SERPINB1ENSG00000021355.81388.058602832.83080-1.0292012.2400010.84550HepG2EIF4B
SERPINB1ENSG00000021355.82792.192902419.218500.206802.345201.78410HepG2ETF1
SERPINB1ENSG00000021355.81414.225301027.477100.460805.618803.91280HepG2FAM120A
SERPINB1ENSG00000021355.81296.737601008.272000.362902.775301.50280HepG2FKBP4
SERPINB1ENSG00000021355.81008.248801574.22870-0.642808.829607.46770HepG2FUBP3
SERPINB1ENSG00000021355.82011.686902935.51420-0.545205.876504.89300HepG2FXR1
SERPINB1ENSG00000021355.81843.107902890.91310-0.649408.223306.67210HepG2G3BP2
SERPINB1ENSG00000021355.81947.095501482.055400.393602.623901.63260HepG2GNB2L1
SERPINB1ENSG00000021355.81076.545201391.81020-0.370604.983903.71180HepG2HDGF
SERPINB1ENSG00000021355.82503.940002017.993300.311203.770102.70530HepG2HNRNPA2B1
SERPINB1ENSG00000021355.81236.626801493.78680-0.272602.749102.03360HepG2HNRNPF
SERPINB1ENSG00000021355.81931.429202757.25600-0.513605.945304.95120HepG2HNRNPK
SERPINB1ENSG00000021355.81753.926502000.30780-0.189602.498601.85560HepG2HNRNPL
SERPINB1ENSG00000021355.81909.332301252.093700.608607.015006.06590HepG2HNRNPLL
SERPINB1ENSG00000021355.81259.416101040.862000.274902.229101.37470HepG2HNRNPM
SERPINB1ENSG00000021355.8922.091101395.44540-0.5977011.7608010.58460HepG2HNRNPU
SERPINB1ENSG00000021355.81466.074202768.14700-0.9170014.6813013.26340HepG2IGF2BP2
SERPINB1ENSG00000021355.81461.795402597.62440-0.829503.718302.57690HepG2IGF2BP3
SERPINB1ENSG00000021355.81225.673201636.03190-0.416602.645601.48600HepG2KHDRBS1
SERPINB1ENSG00000021355.81667.164101311.879800.345703.218001.44380HepG2CCAR2
SERPINB1ENSG00000021355.81579.776001332.633400.245303.128402.04560HepG2KIF1C
SERPINB1ENSG00000021355.81502.567702936.53800-0.9667015.7649014.26140HepG2MAGOH
SERPINB1ENSG00000021355.81751.355402953.00850-0.753709.013407.92840HepG2MATR3
SERPINB1ENSG00000021355.81584.482101025.235200.628008.632106.54810HepG2NAA15
SERPINB1ENSG00000021355.81697.260503022.59680-0.8326011.5396010.28870HepG2NCBP2
SERPINB1ENSG00000021355.83051.715502177.407000.486908.118306.83360HepG2NOL12
SERPINB1ENSG00000021355.81611.953701381.280800.222702.186901.42610HepG2PARN
SERPINB1ENSG00000021355.81116.099902683.88410-1.2659059.4482057.31660HepG2PCBP1
SERPINB1ENSG00000021355.8945.525501129.44610-0.256402.245601.54190HepG2PRPF4
SERPINB1ENSG00000021355.81273.950801828.77620-0.521603.148201.85680HepG2PRPF6
SERPINB1ENSG00000021355.81264.22310934.783000.435403.873002.93690HepG2PRPF8
SERPINB1ENSG00000021355.82068.200402730.99210-0.401007.123806.32670HepG2PTBP1
SERPINB1ENSG00000021355.81310.245102078.48580-0.6657010.537609.47470HepG2PUF60
SERPINB1ENSG00000021355.81575.661702204.77520-0.484707.229706.16310HepG2PUM2
SERPINB1ENSG00000021355.81844.425101484.966300.312604.640103.88170HepG2PUS1
SERPINB1ENSG00000021355.81745.610702957.64730-0.7607018.6591017.23890HepG2QKI
SERPINB1ENSG00000021355.81499.938002684.28700-0.8396017.7312016.12360HepG2RBM25
SERPINB1ENSG00000021355.82416.715203039.29900-0.330705.335604.62380HepG2NELFE
SERPINB1ENSG00000021355.81538.879502830.75390-0.8793031.4686029.80950HepG2RECQL
SERPINB1ENSG00000021355.81285.928701724.09830-0.423002.525001.76000HepG2RPS3A
SERPINB1ENSG00000021355.8843.257501242.71940-0.5595010.349109.22540HepG2SAFB2
SERPINB1ENSG00000021355.8876.318501328.01180-0.599703.716402.93090HepG2SF3A3
SERPINB1ENSG00000021355.8927.703201239.38120-0.417902.764202.05790HepG2SF3B1
SERPINB1ENSG00000021355.81465.876002843.24410-0.9558036.1054034.41600HepG2SF3B4
SERPINB1ENSG00000021355.83095.313801379.008901.166409.011707.60810HepG2SNRNP70
SERPINB1ENSG00000021355.82964.675602283.803900.376307.989007.25940HepG2SRFBP1
SERPINB1ENSG00000021355.82166.251002967.76030-0.4542010.273109.49010HepG2SRSF1
SERPINB1ENSG00000021355.81250.959902052.14620-0.7141019.0541017.61770HepG2SRSF5
SERPINB1ENSG00000021355.82488.609601568.822400.665605.066103.43640HepG2SUB1
SERPINB1ENSG00000021355.82634.234702333.903300.174501.920401.38450HepG2SUCLG1
SERPINB1ENSG00000021355.81396.183801018.723700.454604.777703.55840HepG2SUPT6H
SERPINB1ENSG00000021355.82449.329101205.893601.0222016.6450015.23110HepG2SUPV3L1
SERPINB1ENSG00000021355.8864.906302667.61940-1.6249075.9723073.55970HepG2TAF15
SERPINB1ENSG00000021355.81029.93540808.339800.349402.476501.52710HepG2TFIP11
SERPINB1ENSG00000021355.82060.797102451.09320-0.250202.149901.41110HepG2TIA1
SERPINB1ENSG00000021355.81658.826002030.51660-0.291702.709701.84570HepG2TUFM
SERPINB1ENSG00000021355.8707.255101439.73450-1.025503.241502.17230HepG2U2AF2
SERPINB1ENSG00000021355.81675.519502149.21980-0.359202.664301.84270HepG2UBE2L3
SERPINB1ENSG00000021355.8330.17070712.43870-1.109609.536608.13020HepG2UCHL5
SERPINB1ENSG00000021355.81384.904601177.740000.233702.434701.77250HepG2UPF1
SERPINB1ENSG00000021355.8971.957401137.06700-0.226401.989601.46410HepG2UTP3
SERPINB1ENSG00000021355.82441.374801295.293400.9143041.3808039.91320HepG2ZNF622
SERPINB1ENSG00000021355.81098.526601677.33810-0.610604.707002.97740HepG2ZRANB2
SERPINB1ENSG00000021355.81190.49110946.427700.330902.502001.38560K562AARS
SERPINB1ENSG00000021355.81371.970702688.91940-0.9708018.3990017.05230K562AQR
SERPINB1ENSG00000021355.81550.481901102.766100.491504.553003.42230K562BOP1
SERPINB1ENSG00000021355.82732.183201998.420400.451104.990803.27990K562CIRBP
SERPINB1ENSG00000021355.81552.320301872.88300-0.270802.750501.64870K562CPEB4
SERPINB1ENSG00000021355.81617.646401269.421000.349603.292102.14490K562DDX3X
SERPINB1ENSG00000021355.81172.710201937.75510-0.7245018.1714016.63330K562DDX47
SERPINB1ENSG00000021355.8700.292701092.06250-0.641006.512105.06450K562EFTUD2
SERPINB1ENSG00000021355.81663.710701394.233100.254802.659601.48100K562EIF2S1
SERPINB1ENSG00000021355.82058.679901500.344700.456307.405706.31110K562EIF2S2
SERPINB1ENSG00000021355.8304.61570636.32170-1.062807.456705.76500K562EIF3A
SERPINB1ENSG00000021355.8799.892801169.22880-0.547704.208702.89700K562EIF3D
SERPINB1ENSG00000021355.8850.021901414.22420-0.7344014.0558012.21570K562EIF3G
SERPINB1ENSG00000021355.8954.915201326.18820-0.473804.825903.74020K562EIF4A3
SERPINB1ENSG00000021355.81991.968602622.17950-0.396606.735305.29110K562EIF4G2
SERPINB1ENSG00000021355.81736.747401181.957600.555106.542405.19790K562FIP1L1
SERPINB1ENSG00000021355.81315.55190899.251500.548804.891703.32220K562FKBP4
SERPINB1ENSG00000021355.8969.608501379.17250-0.508307.711606.76930K562FXR1
SERPINB1ENSG00000021355.81113.246201367.94870-0.297202.842601.68680K562GLRX3
SERPINB1ENSG00000021355.81043.850501434.73980-0.458905.196703.73890K562HNRNPA1
SERPINB1ENSG00000021355.81335.662801751.26310-0.390803.991302.69490K562HNRNPL
SERPINB1ENSG00000021355.81192.958101588.79150-0.413405.247204.00260K562HNRNPU
SERPINB1ENSG00000021355.82501.953601602.410200.642708.936707.52010K562HSPD1
SERPINB1ENSG00000021355.81295.661201959.62870-0.596908.736207.19930K562MAGOH
SERPINB1ENSG00000021355.81464.741401955.67010-0.417004.775903.52880K562MATR3
SERPINB1ENSG00000021355.81039.048101438.23120-0.469007.546806.26870K562MTPAP
SERPINB1ENSG00000021355.81673.656501324.337900.337603.317101.96000K562NCBP2
SERPINB1ENSG00000021355.81169.013201915.47890-0.7124012.712909.91940K562PCBP1
SERPINB1ENSG00000021355.8941.208301743.60450-0.8895015.7389013.30450K562PCBP2
SERPINB1ENSG00000021355.81814.011101341.831100.434904.110303.08430K562PPIG
SERPINB1ENSG00000021355.8685.167201062.70350-0.633206.198805.07570K562PRPF8
SERPINB1ENSG00000021355.81560.800901903.89370-0.286702.596701.95010K562PTBP1
SERPINB1ENSG00000021355.82104.488002860.92820-0.443005.705504.53840K562PUF60
SERPINB1ENSG00000021355.83751.305702981.563000.331204.588103.34300K562PUM2
SERPINB1ENSG00000021355.81354.256201896.14260-0.485605.997203.65940K562RBM17
SERPINB1ENSG00000021355.81453.788001825.66740-0.328602.706101.87570K562RBM22
SERPINB1ENSG00000021355.81083.334201392.77310-0.362505.223703.05500K562RPS10
SERPINB1ENSG00000021355.8623.768001082.45460-0.795207.910906.51700K562RPS19
SERPINB1ENSG00000021355.81014.713501497.33030-0.561304.850702.47440K562SAFB2
SERPINB1ENSG00000021355.8700.89180965.75290-0.462504.158902.82050K562SAFB
SERPINB1ENSG00000021355.81087.717401498.30060-0.462005.660104.41020K562SF3B4
SERPINB1ENSG00000021355.81135.292101615.53040-0.5089010.159008.48980K562SRPK2
SERPINB1ENSG00000021355.81148.799401866.43810-0.7002011.8248010.37010K562SRSF1
SERPINB1ENSG00000021355.8817.203401087.08830-0.411704.029103.03300K562SYNCRIP
SERPINB1ENSG00000021355.81285.353801888.98400-0.555406.157005.06640K562TARDBP
SERPINB1ENSG00000021355.81500.997701822.13130-0.279702.404601.64760K562TIA1
SERPINB1ENSG00000021355.8689.70930892.85470-0.372402.269501.42840K562TIAL1
SERPINB1ENSG00000021355.8721.76390948.71580-0.394402.929801.95180K562TRIM56
SERPINB1ENSG00000021355.81059.993401507.66020-0.508309.839608.35350K562WDR43
SERPINB1ENSG00000021355.82505.861603186.21310-0.346503.709002.20590K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SERPINB1 is not available on ENCORE database.





6 RBPs can affect the splicing of SERPINB1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESERPINB1ENSG00000021355.8chr6-2839568283970028387822838920284065228408280.052000.003530.09464includedK562PRPF8
SESERPINB1ENSG00000021355.8chr6-2839568283970028387822838920284065228408280.051000.000050.00324includedK562HNRNPU
SESERPINB1ENSG00000021355.8chr6-2839568283970028387822838920284065228408280.069000.002200.07319includedK562SF3B1
SESERPINB1ENSG00000021355.8chr6-2839568283970028387822838920284065228408280.125000.000000.00002includedK562HNRNPC
MXESERPINB1ENSG00000021355.8chr6-283878228389202840652284082828381152838233284204528420940.127000.001970.049711includedK562SBDS
MXESERPINB1ENSG00000021355.8chr6-283878228389202840652284082828381152838233284204528420940.182000.000110.008681includedK562TIA1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SERPINB1 is not avaliable on ENCORE database.