ICA1

General Information

Gene Name       : ICA1
Gene ID             : ENSG00000003147.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ICA1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ICA1ENSG00000003147.187.661.454.55ENCSR000AEF
HepG2ICA1ENSG00000003147.180.070.080.08ENCSR985KAT
K562ICA1ENSG00000003147.1812.4015.0313.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ICA1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ICA1 RNA is bound by 8 proteins.  







eCLIP assay for ICA1 is not avaliable on ENCORE database.





8 proteins are bound to ICA1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr781967948196869-3'-UTR,CDS,intron-Distal,intron-Proximal4.366163.70678K562BUD13
chr781981788198283-3'-UTR,CDS,intron-Distal,intron-Proximal3.916003.86058K562GRWD1
chr781968168196898-3'-UTR,CDS,intron-Distal,intron-Proximal4.104399.01749K562SF3B4
chr781676258167720-3'-UTR,CDS,intron-Distal3.740136.25299K562ZNF622
chr781981508198258-3'-UTR,CDS,intron-Distal,intron-Proximal4.356376.47664K562ZNF622
chr782580078258099-5'-UTR,CDS,intron-Distal,intron-Proximal3.382027.30210K562ZNF622
chr782579278258020-5'-UTR,CDS,intron-Distal,intron-Proximal4.090679.98860K562UCHL5
chr782682698268304-CDS,intron-Distal,intron-Proximal3.196134.30396K562UCHL5
chr782722178272295-CDS,intron-Distal,intron-Proximal4.368209.20390K562UCHL5
chr781920558192173-intron-Distal5.6561813.68854K562CSTF2T
chr781918578191927-intron-Distal3.243313.17504K562CSTF2T
chr782817738281839-intron-Distal4.394493.59909K562EXOSC5
chr781612128161296-intron-Distal5.1435711.37374K562QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ICA1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ICA1 is not available on ENCORE database.

  • 27 RBPs can affect the levels of ICA1.  








The Knockdown/knockout RNA-Seq assay for ICA1 is not available on ENCORE database.





27 RBPs can affect the gene expression of ICA1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ICA1ENSG00000003147.1352.356101.251605.3864010.557809.58520HepG2AKAP1
ICA1ENSG00000003147.137.499100.0000099999.999902.383401.66410HepG2CALR
ICA1ENSG00000003147.1351.972000.939105.7902013.7382012.31330HepG2PUM2
ICA1ENSG00000003147.1311.264101.152003.289501.881401.36550HepG2RPS19
ICA1ENSG00000003147.131003.602001180.76060-0.234501.996801.49970K562AGGF1
ICA1ENSG00000003147.131010.605301228.63370-0.281801.899701.35420K562AKAP8L
ICA1ENSG00000003147.13327.08270693.65840-1.0846011.7307010.64460K562AQR
ICA1ENSG00000003147.13294.89140474.41160-0.686002.874801.98570K562BOP1
ICA1ENSG00000003147.13581.77040876.62720-0.591503.113201.97720K562CNOT7
ICA1ENSG00000003147.13331.58680504.47020-0.605403.047802.22610K562CPSF6
ICA1ENSG00000003147.13194.56920311.58580-0.679304.096002.96830K562EFTUD2
ICA1ENSG00000003147.13565.55940415.268000.445502.852801.99040K562FIP1L1
ICA1ENSG00000003147.13353.05820513.21950-0.539702.710301.86590K562FMR1
ICA1ENSG00000003147.13346.44450485.87130-0.487903.672702.99100K562FXR1
ICA1ENSG00000003147.13466.02410341.546100.448202.247001.41190K562HNRNPM
ICA1ENSG00000003147.13372.69300532.62650-0.515104.370503.23730K562HNRNPU
ICA1ENSG00000003147.131359.41260563.040101.2716024.1100021.97690K562HSPD1
ICA1ENSG00000003147.13507.64350661.25710-0.381402.633801.81310K562MAGOH
ICA1ENSG00000003147.13413.40910588.34910-0.509103.705402.57500K562PCBP2
ICA1ENSG00000003147.13706.90490489.005600.531603.625102.67230K562PCBP3
ICA1ENSG00000003147.13505.00620375.089300.429002.848702.03520K562POLR2G
ICA1ENSG00000003147.13475.07890642.45520-0.435403.480802.74680K562PTBP1
ICA1ENSG00000003147.13384.64680616.01980-0.679406.345405.00310K562RBM22
ICA1ENSG00000003147.13444.99390308.815500.526902.769501.95300K562RPS19
ICA1ENSG00000003147.13478.95630309.978300.627603.274801.82730K562RRP9
ICA1ENSG00000003147.13306.34590629.82400-1.0398013.6020012.03300K562SRSF1
ICA1ENSG00000003147.13587.87290442.283500.410402.793101.50900K562SSB
ICA1ENSG00000003147.13728.28050530.551800.456903.880602.83780K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ICA1 is not available on ENCORE database.





2 RBPs can affect the splicing of ICA1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEICA1ENSG00000003147.13chr7-8181598818168581813948181447818350481836020.071000.001310.01537includedK562AQR
SEICA1ENSG00000003147.13chr7-817861481786778178469817851181813948181447-0.149000.000420.01114excludedK562U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ICA1 is not avaliable on ENCORE database.