ASH2L

General Information

Gene Name       : ASH2L
Gene ID             : ENSG00000129691.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ASH2L)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ASH2LENSG00000129691.1535.0533.2234.13ENCSR000AEF
HepG2ASH2LENSG00000129691.1526.6437.6532.14ENCSR985KAT
K562ASH2LENSG00000129691.15133.44134.28133.86ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ASH2L is not avaliable on ENCORE database.



Proteins bound to RNA
  • ASH2L RNA is bound by 27 proteins.  







eCLIP assay for ASH2L is not avaliable on ENCORE database.





27 proteins are bound to ASH2L RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr83799735737997390+3'-UTR,intron-Distal3.413853.66308K562UPF1
chr83799328337993290+3'-UTR,CDS,intron-Distal,intron-Proximal5.828328.34710K562AQR
chr83799676137996839+3'-UTR,intron-Distal3.4543714.43961K562PUM2
chr83798640237986408+3'-UTR,CDS3.1519112.83044K562YBX3
chr83799648237996535+3'-UTR,CDS4.980898.32277K562LIN28B
chr83799678237996833+3'-UTR,intron-Distal4.306047.48557K562IGF2BP1
chr83799661437996638+3'-UTR,intron-Proximal5.4156564.61147K562PABPC4
chr83798591237985975+3'-UTR,CDS3.919383.39686HepG2G3BP1
chr83799659837996637+3'-UTR,intron-Proximal4.6369111.63485K562RPS3
chr83799629337996366+3'-UTR,CDS,intron-Proximal3.450383.80334HepG2U2AF2
chr83799699437997049+3'-UTR,intron-Distal3.5595517.38452K562YBX3
chr83799648137996528+3'-UTR,CDS,intron-Proximal4.913186.69987K562RPS3
chr83799319637993282+3'-UTR,CDS,intron-Distal4.042994.75351K562LIN28B
chr83799690137996935+3'-UTR,intron-Distal3.048215.17928K562YBX3
chr83800138238001464+3'-UTR4.960265.28062HepG2XPO5
chr83798636137986402+3'-UTR,CDS3.2556618.51754K562YBX3
chr83799695237997030+3'-UTR,intron-Distal3.065188.58981K562FAM120A
chr83799688837996960+3'-UTR,intron-Distal3.9451110.35092K562LIN28B
chr83799663837996684+3'-UTR,intron-Proximal4.6665873.10271K562PABPC4
chr83796394237963963+5'-UTR,CDS,intron-Distal,intron-Proximal4.797737.21258K562LIN28B
chr83796454937964589+5'-UTR,CDS,intron-Distal3.098984.98113K562YBX3
chr83796790237967987+5'-UTR,CDS,intron-Proximal4.602516.73025HepG2GRWD1
chr83796313737963205+5'-UTR,CDS3.107783.73413HepG2PPIG
chr83796389537963947+5'-UTR,CDS,intron-Distal,intron-Proximal3.321005.26861K562DDX24
chr83796316037963215+5'-UTR,CDS3.713035.42720K562UCHL5
chr83796453337964603+5'-UTR,CDS,intron-Distal,intron-Proximal3.687844.51739HepG2BCLAF1
chr83797422137974304+5'-UTR,CDS,intron-Proximal4.125857.53394K562AQR
chr83797675637976847+5'-UTR,CDS,intron-Proximal3.178963.32027K562SMNDC1
chr83796325237963302+5'-UTR,CDS,intron-Proximal4.747594.13847K562AQR
chr83796305037963183+5'-UTR,CDS3.707426.60593HepG2NCBP2
chr83796451237964649+5'-UTR,CDS,intron-Distal,intron-Proximal4.294907.79098HepG2PRPF8
chr83796453537964605+5'-UTR,CDS,intron-Distal,intron-Proximal5.0829217.39149K562LIN28B
chr83797413437974221+5'-UTR,CDS,intron-Proximal3.330539.16870K562AQR
chr83796365337963711+5'-UTR,CDS,intron-Distal,intron-Proximal3.540077.16774K562AQR
chr83797678437976833+5'-UTR,CDS,intron-Proximal4.004506.22817K562DDX24
chr83796825437968347+5'-UTR,CDS,intron-Proximal3.407266.88650HepG2GRWD1
chr83796347637963546+5'-UTR,intron-Distal,intron-Proximal3.9957010.49508K562DDX3X
chr83796453537964646+5'-UTR,CDS,intron-Distal,intron-Proximal3.569498.12996HepG2PPIG
chr83796459837964684+CDS,intron-Distal3.9933217.21804K562PUM2
chr83796464937964787+CDS,intron-Distal,intron-Proximal3.0796210.46843K562PRPF8
chr83796797937968029+CDS,intron-Proximal3.492115.75231K562AQR
chr83797147337971568+intron-Distal3.749747.93121K562KHSRP
chr83798562737985751+intron-Distal,intron-Proximal3.421354.56724K562KHSRP
chr83797997637979999+intron-Distal4.070263.67527K562SMNDC1
chr83797252137972635+intron-Distal,intron-Proximal3.0764111.59383K562AQR
chr83796442337964457+intron-Distal,intron-Proximal4.176913.85435K562PRPF8
chr83798111637981198+intron-Distal4.974577.88729K562TARDBP
chr83797254037972630+intron-Distal,intron-Proximal4.140986.31048K562RBM22
chr83796698537967062+intron-Distal3.817086.86368K562PTBP1
chr83796519937965251+intron-Distal4.595845.71021K562TARDBP
chr83797461937974751+intron-Distal4.4635613.30452HepG2QKI
chr83799334537993391+intron-Distal,intron-Proximal3.353343.08090K562AQR
chr83797261737972696+intron-Distal,intron-Proximal3.392405.66421K562PRPF8
chr83797463737974796+intron-Distal3.3140510.90693K562QKI
chr83799329037993318+intron-Distal,intron-Proximal5.112279.56266K562AQR
chr83797485637974915+intron-Distal,intron-Proximal4.970055.54528HepG2QKI
chr83797158637971679+intron-Distal,intron-Proximal4.163297.08005HepG2QKI
chr83797156337971677+intron-Distal,intron-Proximal4.809568.50955K562QKI
chr83799331837993325+intron-Distal,intron-Proximal5.1323410.08262K562AQR
chr83796706237967134+intron-Distal4.622803.55787K562PTBP1
chr83796471537964772+intron-Distal,intron-Proximal3.818034.95583K562RBM22
chr83797475137974832+intron-Distal3.571076.82051HepG2QKI
chr83796835437968410+intron-Proximal4.929355.17615K562AQR
chr83797867237978744+intron-Proximal3.734826.06472K562AQR
chr83797424537974302+intron-Proximal3.808434.58287K562PRPF8
chr83797672837976774+intron-Proximal5.724137.91936K562SF3B4
chr83797688137976944+intron-Proximal4.721835.17615K562AQR
chr83798646937986527+intron-Proximal3.123634.20978K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ASH2L is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ASH2L is not available on ENCORE database.

  • 82 RBPs can affect the levels of ASH2L.  








The Knockdown/knockout RNA-Seq assay for ASH2L is not available on ENCORE database.





82 RBPs can affect the gene expression of ASH2L :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ASH2LENSG00000129691.11864.487401225.23540-0.503103.588902.52120HepG2ABCF1
ASH2LENSG00000129691.11743.22960908.62570-0.289902.796602.18630HepG2ACO1
ASH2LENSG00000129691.11629.34600876.27180-0.477503.153302.04360HepG2AKAP8
ASH2LENSG00000129691.11636.18300913.70470-0.522303.551802.49220HepG2BCCIP
ASH2LENSG00000129691.111362.902101079.718700.335902.302601.59250HepG2CIRBP
ASH2LENSG00000129691.11771.19010908.32640-0.236102.089101.49930HepG2CKAP4
ASH2LENSG00000129691.11481.19900859.37910-0.836709.315608.12650HepG2CPSF6
ASH2LENSG00000129691.111114.43830828.639400.427404.939803.42200HepG2DDX1
ASH2LENSG00000129691.11650.130501130.02690-0.797606.472605.55830HepG2DDX6
ASH2LENSG00000129691.11673.86380805.37680-0.257202.272101.66850HepG2DNAJC2
ASH2LENSG00000129691.11687.694201086.58440-0.660004.479003.73500HepG2EIF2S1
ASH2LENSG00000129691.11530.50120781.02850-0.558003.845402.79020HepG2EIF3D
ASH2LENSG00000129691.11872.234501169.03220-0.422502.201801.58520HepG2EIF4B
ASH2LENSG00000129691.11882.368801251.72660-0.504504.832703.77500HepG2EIF4G2
ASH2LENSG00000129691.111302.064501655.68250-0.346604.539203.80430HepG2ETF1
ASH2LENSG00000129691.11816.269601237.22510-0.600004.437103.47890HepG2FIP1L1
ASH2LENSG00000129691.11451.13350695.38730-0.624305.006103.80080HepG2GEMIN5
ASH2LENSG00000129691.11381.68950542.22420-0.506502.417401.37560HepG2GRSF1
ASH2LENSG00000129691.111092.73140867.415700.333003.734102.61180HepG2HDGF
ASH2LENSG00000129691.11963.883001217.25650-0.336703.852802.77710HepG2HNRNPA2B1
ASH2LENSG00000129691.11869.355901272.31340-0.549408.767307.58100HepG2HNRNPF
ASH2LENSG00000129691.11586.887301137.54340-0.954808.329407.16980HepG2HNRNPK
ASH2LENSG00000129691.111018.123101206.57520-0.245002.712502.04520HepG2HNRNPL
ASH2LENSG00000129691.11893.278001252.87290-0.488105.544704.55750HepG2IGF2BP1
ASH2LENSG00000129691.11791.10090925.87200-0.227002.311401.63450HepG2ILF2
ASH2LENSG00000129691.11782.577801211.72580-0.630804.713903.86430HepG2MAGOH
ASH2LENSG00000129691.11932.860501313.40710-0.493606.518105.35240HepG2NOL12
ASH2LENSG00000129691.11544.43280824.33000-0.598505.357104.33190HepG2NSUN2
ASH2LENSG00000129691.11652.81350897.18400-0.458705.394904.26590HepG2PARN
ASH2LENSG00000129691.11921.480401160.33280-0.332503.856403.16490HepG2PCBP1
ASH2LENSG00000129691.11740.325701329.92270-0.8451015.5437014.03410HepG2PUM2
ASH2LENSG00000129691.111561.01650925.479300.7541010.944609.85800HepG2PUS1
ASH2LENSG00000129691.111322.90840878.461200.590603.082202.34040HepG2RAVER1
ASH2LENSG00000129691.11854.247301383.85270-0.6960012.2904011.35820HepG2RBM22
ASH2LENSG00000129691.11755.851501313.97210-0.7978016.9869015.86650HepG2NELFE
ASH2LENSG00000129691.11778.218001223.71400-0.6530011.9635010.81650HepG2RECQL
ASH2LENSG00000129691.11874.372501370.48200-0.648407.792906.73700HepG2RPLP0
ASH2LENSG00000129691.11531.63150760.03640-0.515604.624503.85140HepG2RPS19
ASH2LENSG00000129691.11436.38520685.47430-0.651504.731003.73440HepG2RRP9
ASH2LENSG00000129691.11731.417401229.27850-0.7490015.1090013.89440HepG2SF3B4
ASH2LENSG00000129691.11658.90490895.52970-0.442702.427501.53380HepG2SMNDC1
ASH2LENSG00000129691.111015.019001563.02560-0.6228013.3376012.45690HepG2SRFBP1
ASH2LENSG00000129691.111847.543801283.065400.5259010.064609.28790HepG2SRSF1
ASH2LENSG00000129691.11934.583001249.98020-0.419504.019403.20510HepG2SRSF7
ASH2LENSG00000129691.11515.543601043.81180-1.0177025.4024024.04470HepG2SRSF9
ASH2LENSG00000129691.11542.71990826.51090-0.606804.269802.76350HepG2STAU1
ASH2LENSG00000129691.11670.47480894.29870-0.415602.595201.93770HepG2SUPV3L1
ASH2LENSG00000129691.11700.09760888.62800-0.344003.498802.88050HepG2TRIM56
ASH2LENSG00000129691.11311.43510528.27730-0.762406.392405.23310HepG2UCHL5
ASH2LENSG00000129691.11670.34510944.21510-0.494206.601705.59840HepG2UPF1
ASH2LENSG00000129691.11465.15810818.85560-0.815905.984704.46830HepG2UPF2
ASH2LENSG00000129691.115707.437306583.18650-0.205903.045502.45400K562AGGF1
ASH2LENSG00000129691.115684.136906850.09410-0.269202.409501.79950K562AKAP8L
ASH2LENSG00000129691.114000.883506983.55050-0.8036016.1609014.90150K562AQR
ASH2LENSG00000129691.113091.485604294.01500-0.4740010.157107.57420K562BCCIP
ASH2LENSG00000129691.114619.674606342.76580-0.4573010.543908.39210K562CPEB4
ASH2LENSG00000129691.112845.837603735.17340-0.392304.906303.46490K562DDX3X
ASH2LENSG00000129691.117681.108606563.469000.226803.021902.34440K562DDX47
ASH2LENSG00000129691.112498.904003722.07410-0.574807.301505.75270K562EFTUD2
ASH2LENSG00000129691.112666.195703902.29490-0.549507.853606.47140K562EIF4A3
ASH2LENSG00000129691.113045.343203768.68520-0.307502.563001.74070K562FMR1
ASH2LENSG00000129691.112402.242503194.31230-0.411103.631202.57160K562FTO
ASH2LENSG00000129691.112684.797003731.61550-0.475004.689402.80960K562GEMIN5
ASH2LENSG00000129691.114123.339707098.85710-0.7838017.6286015.66850K562GRSF1
ASH2LENSG00000129691.113717.383104908.99280-0.401105.497104.00370K562HNRNPA1
ASH2LENSG00000129691.113211.932404340.57520-0.434405.341104.53660K562HNRNPC
ASH2LENSG00000129691.112949.823403875.67000-0.393804.251102.79990K562HNRNPF
ASH2LENSG00000129691.114463.613005436.09420-0.284403.900402.83520K562HNRNPU
ASH2LENSG00000129691.113804.602704997.01760-0.393304.408702.82790K562IGF2BP3
ASH2LENSG00000129691.112317.846103019.61230-0.381602.442801.57190K562KRR1
ASH2LENSG00000129691.113335.582604401.33380-0.400003.607401.88120K562LIN28B
ASH2LENSG00000129691.113619.006705162.98610-0.512607.768006.33330K562MAGOH
ASH2LENSG00000129691.116950.571908143.89130-0.228602.249201.44380K562MBNL1
ASH2LENSG00000129691.112769.745303451.85560-0.317603.236302.28640K562METAP2
ASH2LENSG00000129691.113819.423305128.05420-0.4251011.317309.80110K562MTPAP
ASH2LENSG00000129691.113256.325604593.71350-0.496406.962805.38940K562PCBP2
ASH2LENSG00000129691.116801.894708716.35470-0.357805.080703.21550K562PNPT1
ASH2LENSG00000129691.112827.623703622.00340-0.357203.200002.39280K562PRPF8
ASH2LENSG00000129691.112826.754003891.64990-0.461205.844204.45400K562PSIP1
ASH2LENSG00000129691.113959.640805016.19120-0.341204.146903.35030K562PTBP1
ASH2LENSG00000129691.117860.069109255.26680-0.235702.452301.68580K562PUF60
ASH2LENSG00000129691.118336.015809645.56560-0.210502.905501.92250K562PUM2
ASH2LENSG00000129691.115408.793506793.48430-0.328803.007002.44500K562PUS1
ASH2LENSG00000129691.114010.444204809.73200-0.262202.163601.42500K562RBM22
ASH2LENSG00000129691.114918.113803703.446100.409102.791501.45950K562RRP9
ASH2LENSG00000129691.113160.652805011.79080-0.665102.645801.48130K562SF1
ASH2LENSG00000129691.112361.488803363.21400-0.510104.814903.50630K562SF3B1
ASH2LENSG00000129691.113097.341604244.78180-0.454707.379705.93770K562SF3B4
ASH2LENSG00000129691.112541.938703365.36770-0.404803.950702.65710K562SRFBP1
ASH2LENSG00000129691.114531.583805760.05550-0.346109.486607.86600K562SRPK2
ASH2LENSG00000129691.113432.576604976.82500-0.535906.718905.57450K562TARDBP
ASH2LENSG00000129691.114004.562804800.73250-0.261602.673601.87080K562TIA1
ASH2LENSG00000129691.113003.046103743.19260-0.317802.381301.51740K562TIAL1
ASH2LENSG00000129691.113012.523003975.95620-0.400304.498603.22710K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ASH2L is not available on ENCORE database.





29 RBPs can affect the splicing of ASH2L :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.100000.001730.03262excludedK562SRSF1
SEASH2LENSG00000129691.11chr8+379931853799328437990971379910643799633337996393-0.061000.000670.01510excludedK562SF3B4
SEASH2LENSG00000129691.11chr8+379635063796365737963067379632563796389537963962-0.160000.000000.00546excludedK562TIA1
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.239000.000000.00001excludedK562XRN2
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.125000.000140.02789excludedK562MATR3
SEASH2LENSG00000129691.11chr8+379717093797180537968256379683513797242237972518-0.067000.000000.00000excludedK562AKAP8L
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.189000.000000.00451excludedK562GEMIN5
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.166000.000040.07033excludedK562LIN28B
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.354000.000130.00243excludedHepG2U2AF2
SEASH2LENSG00000129691.11chr8+3796350637963657379630673796325637963895379639620.119000.000540.02417includedK562FXR1
SEASH2LENSG00000129691.11chr8+3799315437993284379909713799106437996333379964030.124000.000100.02544includedK562DROSHA
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.209000.000000.00002excludedK562SUPV3L1
SEASH2LENSG00000129691.11chr8+379717093797180537968256379683513797242237972518-0.080000.000000.00000excludedK562PUS1
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.206000.000000.00008excludedK562MTPAP
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.234000.000000.00001excludedK562UCHL5
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.201000.000010.00129excludedHepG2FTO
SEASH2LENSG00000129691.11chr8+379717093797180537968256379683513797242237972518-0.081000.000000.00012excludedK562U2AF1
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.242000.000130.01374excludedHepG2HNRNPL
SEASH2LENSG00000129691.11chr8+3797678737976881379682563796835137978449379786670.105000.000520.08036includedK562FXR2
SEASH2LENSG00000129691.11chr8+379717093797180537968256379683513797242237972518-0.063000.000000.00001excludedK562UTP18
SEASH2LENSG00000129691.11chr8+379717093797180537968256379683513797242237972518-0.055000.000400.00925excludedK562U2AF2
SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.133000.000110.00684excludedK562TARDBP
SEASH2LENSG00000129691.11chr8+3796350237963657379630673796325637963895379639620.115000.000960.02647includedK562RBM15
SEASH2LENSG00000129691.11chr8+379717093797180537968256379683513797242237972518-0.054000.000000.00003excludedK562RBM15
SEASH2LENSG00000129691.11chr8+379717093797180537968256379683513797242237972518-0.067000.000000.00000excludedK562AGGF1
SEASH2LENSG00000129691.11chr8+3796350237963657379630673796325637963895379639620.139000.000080.05525includedK562AARS
SEASH2LENSG00000129691.11chr8+3796350237963657379630673796325637963895379639620.123000.000000.00050includedK562HNRNPK
A3SSASH2LENSG00000129691.11chr8+3797844937978667379784713797866737968256379683510.726000.009680.05146longerK562AQR
MXEASH2LENSG00000129691.11chr8+3799097137991064379931853799328437986275379864693799633337996393-0.128000.000050.009652includedK562HNRNPL
MXEASH2LENSG00000129691.11chr8+3799097137991064379931853799328437986275379864693799633337996393-0.240000.000000.000072includedK562DROSHA
MXEASH2LENSG00000129691.11chr8+37972422379725183797416737974243379682563796835137976787379768810.083000.000020.000731includedK562U2AF1
MXEASH2LENSG00000129691.11chr8+37972422379725183797416737974243379682563796835137976787379768810.055000.000000.000001includedK562PUS1
MXEASH2LENSG00000129691.11chr8+37972422379725183797416737974243379682563796835137976787379768810.078000.000070.001931includedK562U2AF2
MXEASH2LENSG00000129691.11chr8+37972422379725183797416737974243379682563796835137976787379768810.054000.000030.001431includedK562TARDBP
MXEASH2LENSG00000129691.11chr8+3799097137991064379931853799328437986275379864693799633337996393-0.141000.000000.000102includedK562SBDS
MXEASH2LENSG00000129691.11chr8+37990971379910643799318537993284379862753798646937996333379963930.194000.000420.056031includedHepG2XRCC6
MXEASH2LENSG00000129691.11chr8+37972422379725183799097137991064379682563796835137996333379963930.298000.001320.092631includedK562NPM1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ASH2L is not avaliable on ENCORE database.