NLK

General Information

Gene Name       : NLK
Gene ID             : ENSG00000087095.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NLK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NLKENSG00000087095.1215.6310.5613.10ENCSR000AEF
HepG2NLKENSG00000087095.125.677.856.76ENCSR985KAT
K562NLKENSG00000087095.1222.0122.6522.33ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NLK is not avaliable on ENCORE database.



Proteins bound to RNA
  • NLK RNA is bound by 16 proteins.  







eCLIP assay for NLK is not avaliable on ENCORE database.





16 proteins are bound to NLK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr172652222526522295+3'-UTR,intron-Distal3.055604.90505K562FAM120A
chr172652224326522273+3'-UTR,intron-Distal4.939667.65820K562LIN28B
chr172652270826522783+3'-UTR,intron-Distal4.1696316.07524K562PUM2
chr172652173226521779+3'-UTR,intron-Proximal5.027315.69951K562AQR
chr172652221626522243+3'-UTR,intron-Distal3.899206.87736K562LIN28B
chr172652170026521863+3'-UTR,intron-Distal,intron-Proximal3.657535.32884K562KHSRP
chr172652244426522526+3'-UTR,intron-Distal4.008967.06274K562PUM2
chr172652216526522225+3'-UTR,intron-Distal3.646376.61024K562FAM120A
chr172636954726369581+5'-UTR,intron-Distal3.770964.68928K562RBM15
chr172636988326369928+5'-UTR,CDS,intron-Distal4.036356.06042K562RBM15
chr172637010726370132+CDS,intron-Proximal4.073353.73926K562RBM15
chr172637029026370367+CDS,intron-Proximal3.231424.99842HepG2PPIG
chr172644959626449669+CDS,intron-Proximal5.378169.50483HepG2U2AF2
chr172637017726370226+CDS4.744739.04978K562RBM15
chr172639900626399105+intron-Distal3.739894.94630K562QKI
chr172636893226368999+intron-Distal3.402803.19036K562XRN2
chr172638897426389048+intron-Distal3.944227.34576K562HNRNPL
chr172637265126372722+intron-Distal3.510275.20123K562KHSRP
chr172638896926389096+intron-Distal3.448076.94724HepG2HNRNPL
chr172643892126439028+intron-Distal6.5843515.43836K562EIF4G2
chr172640486826404919+intron-Distal4.255693.16986HepG2QKI
chr172636891926369009+intron-Distal4.043453.16051HepG2PPIG
chr172641792626417996+intron-Distal3.708945.40624K562KHSRP
chr172642429526424356+intron-Distal4.561216.58261K562KHSRP
chr172642468826424747+intron-Distal3.921353.26999K562KHSRP
chr172648049226480597+intron-Distal4.008313.16986HepG2QKI
chr172643553426435602+intron-Distal3.832403.29026K562KHDRBS1
chr172639777626397887+intron-Distal4.346398.39533K562QKI
chr172639316726393268+intron-Distal4.632425.14122HepG2PCBP2
chr172640279326402895+intron-Distal5.263639.42242HepG2PCBP2
chr172644106626441143+intron-Distal4.050428.20650K562KHSRP
chr172641708226417189+intron-Distal3.787396.69500K562KHSRP
chr172639308526393243+intron-Distal3.546807.23603K562PTBP1
chr172643689226436963+intron-Distal3.995403.26999K562KHSRP
chr172637272226372774+intron-Distal4.613475.44709K562KHSRP
chr172639332526393421+intron-Distal3.461544.03313K562HNRNPL
chr172636893626368996+intron-Distal6.2058915.69259K562RBM15
chr172644116026441289+intron-Distal5.6381012.38486K562KHSRP
chr172643713026437235+intron-Distal3.514575.38829K562KHSRP
chr172641678726416853+intron-Distal4.189603.92684K562KHSRP
chr172646040326460498+intron-Distal3.081885.39758K562KHSRP
chr172642901226429133+intron-Distal3.364276.24191K562KHSRP
chr172641565726415725+intron-Distal3.065883.51696K562KHSRP
chr172636907526369138+intron-Distal3.670886.19583K562RBM15
chr172642913326429218+intron-Distal5.0784010.14821K562KHSRP
chr172641536926415455+intron-Distal3.609103.02234K562KHSRP
chr172642415426424245+intron-Distal3.829653.06150K562KHSRP
chr172644099326441066+intron-Distal5.048218.57760K562KHSRP
chr172639309926393282+intron-Distal4.826014.74221HepG2PTBP1
chr172643672226436814+intron-Distal3.146523.60684K562KHSRP
chr172644791026448043+intron-Distal3.278414.16402K562TARDBP
chr172636879426368837+intron-Proximal3.636113.63681K562RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NLK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NLK is not available on ENCORE database.

  • 77 RBPs can affect the levels of NLK.  








The Knockdown/knockout RNA-Seq assay for NLK is not available on ENCORE database.





77 RBPs can affect the gene expression of NLK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NLKENSG00000087095.8872.64990472.900100.883808.141507.28060HepG2AKAP1
NLKENSG00000087095.8777.31020487.066000.674303.853703.06900HepG2AUH
NLKENSG00000087095.8387.26890273.494600.501702.122701.33090HepG2BCLAF1
NLKENSG00000087095.8774.92520544.418600.509204.030403.32360HepG2BOP1
NLKENSG00000087095.8557.27090415.344900.424002.822702.04370HepG2CALR
NLKENSG00000087095.8483.51330386.954600.321302.244501.63610HepG2CKAP4
NLKENSG00000087095.8625.37960336.008000.896105.781304.67650HepG2CNOT7
NLKENSG00000087095.8576.79560478.583100.269201.950701.31230HepG2DAZAP1
NLKENSG00000087095.8466.07020271.662800.778606.419905.43510HepG2DDX21
NLKENSG00000087095.8649.37580453.046300.519303.371402.68980HepG2DDX3X
NLKENSG00000087095.8246.69330322.96020-0.388602.032101.41980HepG2DNAJC21
NLKENSG00000087095.8358.93140243.170900.561602.923401.99800HepG2EIF3D
NLKENSG00000087095.8597.56570472.179000.339702.640201.81930HepG2EIF4G1
NLKENSG00000087095.8964.02050559.249600.7855013.0518011.90420HepG2ETF1
NLKENSG00000087095.8496.37400378.206400.392202.413201.63490HepG2EWSR1
NLKENSG00000087095.8705.99990528.102200.418802.286301.58340HepG2FIP1L1
NLKENSG00000087095.8212.69490301.03870-0.501202.224601.51280HepG2FUBP3
NLKENSG00000087095.8232.24110326.05410-0.489502.511601.89280HepG2HNRNPA1
NLKENSG00000087095.8267.67430391.65020-0.549102.864702.15340HepG2HNRNPK
NLKENSG00000087095.8295.07860435.94290-0.563004.917004.03810HepG2HNRNPL
NLKENSG00000087095.8351.75770455.81260-0.373902.067301.43520HepG2IGF2BP1
NLKENSG00000087095.8589.71520427.515600.463903.348702.46190HepG2MSI2
NLKENSG00000087095.8355.68020474.56370-0.416002.717101.96060HepG2NOL12
NLKENSG00000087095.8717.33520382.558700.906908.304607.06760HepG2PABPC4
NLKENSG00000087095.8242.57820321.33600-0.405602.214001.54740HepG2PPIL4
NLKENSG00000087095.8347.37740238.681500.541302.343401.59680HepG2PRPF8
NLKENSG00000087095.8333.39470415.81010-0.318701.776201.31830HepG2PTBP1
NLKENSG00000087095.8281.62960394.22780-0.485203.599302.91570HepG2PUS1
NLKENSG00000087095.8614.02970450.346900.447203.383102.70130HepG2QKI
NLKENSG00000087095.8210.23470315.36430-0.585001.985501.37860HepG2RAVER1
NLKENSG00000087095.81014.08220467.422401.1173023.3129022.10530HepG2RBM22
NLKENSG00000087095.8282.48620430.99010-0.609505.020904.22100HepG2RECQL
NLKENSG00000087095.8442.21830309.689700.513802.232401.38260HepG2RPS10
NLKENSG00000087095.8342.63620236.617300.534002.995902.36030HepG2RPS19
NLKENSG00000087095.8505.26150341.312000.565803.778102.84700HepG2RPS2
NLKENSG00000087095.8395.27360236.097000.743404.002003.07830HepG2RRP9
NLKENSG00000087095.8240.33150320.84180-0.416802.427201.81750HepG2SAFB2
NLKENSG00000087095.8612.12330462.847000.403201.884701.32560HepG2SF3A3
NLKENSG00000087095.8993.50200527.924300.9121018.7980017.79810HepG2SRFBP1
NLKENSG00000087095.8566.09100451.874000.325002.101801.67380HepG2SRSF1
NLKENSG00000087095.8590.32900458.342400.365002.834802.31770HepG2SSB
NLKENSG00000087095.8295.34820406.14840-0.459603.143002.55020HepG2TAF15
NLKENSG00000087095.8275.50950353.20170-0.358402.129601.62240HepG2TRIM56
NLKENSG00000087095.8662.18240451.816400.551404.098503.34020HepG2U2AF1
NLKENSG00000087095.8786.94790392.104001.004902.984501.95650HepG2U2AF2
NLKENSG00000087095.8496.50240396.297000.325102.049501.51830HepG2UTP3
NLKENSG00000087095.8513.15880346.767100.565302.899801.81570HepG2XRCC6
NLKENSG00000087095.8527.67760363.042500.539405.477504.58360HepG2ZC3H8
NLKENSG00000087095.8682.60500451.443400.596408.185107.37360HepG2ZNF622
NLKENSG00000087095.81339.288001590.89910-0.248402.615902.06060K562AGGF1
NLKENSG00000087095.81048.089801364.31680-0.380403.176301.79160K562CIRBP
NLKENSG00000087095.81220.521301623.98230-0.412005.734304.09230K562CPEB4
NLKENSG00000087095.81930.963202320.91960-0.265402.663701.70680K562CELF1
NLKENSG00000087095.81350.712201680.43610-0.315103.985003.22260K562DDX47
NLKENSG00000087095.8700.92510886.05430-0.338103.019601.63940K562DDX6
NLKENSG00000087095.8781.51220959.93500-0.296702.719401.52640K562EIF2S1
NLKENSG00000087095.81926.064401035.637400.8950024.3373022.55620K562EIF2S2
NLKENSG00000087095.8531.02110761.67470-0.520405.488904.38180K562EIF3G
NLKENSG00000087095.8703.18350913.04490-0.376802.800201.97360K562EIF4A3
NLKENSG00000087095.8658.21440822.24320-0.321002.653401.53100K562EIF4B
NLKENSG00000087095.8964.012401238.08600-0.361002.843801.98310K562FIP1L1
NLKENSG00000087095.81122.94160757.152600.568505.000603.40750K562FKBP4
NLKENSG00000087095.8795.27460949.52770-0.255801.975901.44770K562FXR1
NLKENSG00000087095.81001.943401380.13490-0.462004.609103.63480K562GRSF1
NLKENSG00000087095.8705.825001067.10420-0.596307.244705.57510K562HNRNPA1
NLKENSG00000087095.8951.939401294.65140-0.443604.238502.69270K562IGF2BP3
NLKENSG00000087095.8428.53650608.85760-0.506703.462001.78580K562ILF3
NLKENSG00000087095.8720.662101335.14790-0.8896016.0081013.70530K562MATR3
NLKENSG00000087095.8893.898601251.20690-0.485104.926303.73760K562METAP2
NLKENSG00000087095.81288.930602011.77580-0.642308.723506.77430K562MSI2
NLKENSG00000087095.8763.296001147.28480-0.587909.838808.41690K562MTPAP
NLKENSG00000087095.81501.333301939.39740-0.369404.008802.31060K562PNPT1
NLKENSG00000087095.81131.666001405.43730-0.312602.224901.49160K562PPIG
NLKENSG00000087095.8895.75120680.880100.395602.681801.94370K562PRPF8
NLKENSG00000087095.8847.796401299.76930-0.616508.524507.40050K562PTBP1
NLKENSG00000087095.81288.169301641.76540-0.349902.474101.95430K562PUS1
NLKENSG00000087095.8918.070901246.43990-0.441104.007202.97890K562RBM22
NLKENSG00000087095.8599.46720959.89440-0.679207.835204.95770K562RECQL
NLKENSG00000087095.81529.002701288.689500.246602.882901.93100K562SRPK2
NLKENSG00000087095.8801.501101274.18330-0.668809.302708.01660K562SRSF1
NLKENSG00000087095.8879.607201203.31100-0.452104.035402.72570K562SRSF5
NLKENSG00000087095.81111.77300824.601400.431004.476203.42500K562SYNCRIP
NLKENSG00000087095.8809.067701289.60820-0.672607.732006.47820K562TARDBP
NLKENSG00000087095.8962.853201243.95920-0.369603.428102.50170K562TIA1
NLKENSG00000087095.8430.65870697.74720-0.696206.101704.51880K562UCHL5
NLKENSG00000087095.81624.459401351.621300.265203.004802.25610K562UPF1
NLKENSG00000087095.81122.793601501.79170-0.419603.212801.91240K562UTP3
NLKENSG00000087095.81339.209501743.64870-0.380703.523302.52910K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NLK is not available on ENCORE database.





5 RBPs can affect the splicing of NLK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENLKENSG00000087095.8chr17+2637365326373857263702982637035726374942263759500.093000.011680.09184includedK562AQR
SENLKENSG00000087095.8chr17+265122042651229126499542264996442651804626518245-0.145000.000010.00015excludedK562AQR
SENLKENSG00000087095.8chr17+264905682649065426459645264598352649547326495683-0.113000.000200.00318excludedK562AQR
SENLKENSG00000087095.8chr17+265180462651824526512204265122912651914526519239-0.137000.002870.05313excludedK562U2AF1
SENLKENSG00000087095.8chr17+2637365326373857263698642637035726374942263759500.457000.000750.05151includedK562HNRNPL
A3SSNLKENSG00000087095.8chr17+2651801426518245265180462651824526512204265122910.060000.000240.00194longerK562AQR
RINLKENSG00000087095.8chr17+265216072652340726521607265217342652320526523407-0.111000.001380.08313excludedK562ZC3H8
MXENLKENSG00000087095.8chr17+26459645264598352649056826490654263700552637035726495473264956830.079000.000020.000261includedK562AQR
MXENLKENSG00000087095.8chr17+26499542264996442651220426512291264954732649568326518046265182450.167000.000250.002731includedK562AQR
MXENLKENSG00000087095.8chr17+26518046265182452651914526519239264995422649964426521607265217340.152000.000280.003001includedK562AQR
MXENLKENSG00000087095.8chr17+26518014265182452651914526519239264995422649964426521607265217340.052000.009790.062231includedK562AQR
MXENLKENSG00000087095.8chr17+26518014265182452651914526519239265122042651229126521607265217340.075000.001910.015981includedK562AQR
MXENLKENSG00000087095.8chr17+26518014265182452651904826519239265122042651229126521607265217340.076000.002010.016701includedK562AQR
MXENLKENSG00000087095.8chr17+2644962826449758264596452645983526370055263703572649547326495683-0.162000.001170.010512includedK562AQR
MXENLKENSG00000087095.8chr17+26449628264497582649056826490654263700552637035726495473264956830.162000.013440.068671includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NLK is not avaliable on ENCORE database.