HGS

General Information

Gene Name : HGS
Gene ID : ENSG00000185359.12
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: HGS)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	HGS	ENSG00000185359.12	18.41	34.73	26.57	ENCSR000AEF
HepG2	HGS	ENSG00000185359.12	103.82	67.85	85.83	ENCSR985KAT
K562	HGS	ENSG00000185359.12	90.99	86.00	88.50	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for HGS is not avaliable on ENCORE database.

Proteins bound to RNA

HGS RNA is bound by 45 proteins.

CanvasJS.com

eCLIP assay for HGS is not avaliable on ENCORE database.

45 proteins are bound to HGS RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr17	79663330	79663379	+	intron-Proximal	5.92617	33.32844	HepG2	SF3B4
chr17	79657654	79657729	+	CDS,intron-Proximal	5.07339	32.69953	K562	SF3B4
chr17	79657313	79657485	+	intron-Distal,intron-Proximal	6.85249	32.05312	K562	EFTUD2
chr17	79660470	79660556	+	CDS,intron-Proximal	6.18039	29.90936	K562	SF3B4
chr17	79662729	79662812	+	intron-Distal,intron-Proximal	5.32389	29.17509	HepG2	SF3A3
chr17	79668879	79669035	+	3'-UTR,intron-Distal,intron-Proximal	5.45107	28.20392	HepG2	PABPN1
chr17	79653394	79653428	+	3'-UTR,5'-UTR,CDS,intron-Proximal	4.59092	27.98414	HepG2	PRPF8
chr17	79660244	79660400	+	intron-Distal	6.27579	27.14193	HepG2	XPO5
chr17	79653428	79653462	+	intron-Proximal	4.54687	26.88914	HepG2	PRPF8
chr17	79655636	79655741	+	CDS,intron-Distal,intron-Proximal	4.05044	26.68321	K562	SF3B4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 289 entries

eCLIP assay for HGS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for HGS is not available on ENCORE database.
117 RBPs can affect the levels of HGS.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for HGS is not available on ENCORE database.

117 RBPs can affect the gene expression of HGS :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
HGS	ENSG00000185359.8	3290.41390	1738.68750	0.92020	49.41390	47.84580	HepG2	ZNF622
HGS	ENSG00000185359.8	3898.26830	2149.88200	0.85850	38.60140	37.29500	HepG2	SRFBP1
HGS	ENSG00000185359.8	2569.86020	1409.33830	0.86660	38.92440	37.22640	HepG2	PUM1
HGS	ENSG00000185359.8	2198.02630	931.60280	1.23830	34.51900	32.06480	K562	SRSF1
HGS	ENSG00000185359.8	2555.65250	1304.43650	0.97020	32.89680	31.18420	HepG2	CELF1
HGS	ENSG00000185359.8	2364.33610	1310.84560	0.85080	27.73820	26.03730	HepG2	SRSF5
HGS	ENSG00000185359.8	1650.43760	878.81370	0.90910	26.44930	24.92990	HepG2	TRIM56
HGS	ENSG00000185359.8	1632.69090	930.96680	0.81040	26.07740	24.43050	HepG2	SMN1
HGS	ENSG00000185359.8	2479.66940	1490.77720	0.73400	25.33560	23.76360	HepG2	SUCLG1
HGS	ENSG00000185359.8	1869.58010	1100.75920	0.76410	19.91160	18.69830	HepG2	PTBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 138 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for HGS is not available on ENCORE database.

30 RBPs can affect the splicing of HGS :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	HGS	ENSG00000185359.8	chr17	+	79668273	79668452	79668074	79668161	79668537	79669149	-0.25600	0.00000	0.00017	excluded	K562	PRPF8
SE	HGS	ENSG00000185359.8	chr17	+	79657211	79657264	79655733	79655857	79657703	79657860	-0.21600	0.00000	0.00000	excluded	HepG2	U2AF1
SE	HGS	ENSG00000185359.8	chr17	+	79657211	79657264	79655733	79655857	79657703	79657860	-0.12600	0.00000	0.00003	excluded	HepG2	U2AF2
SE	HGS	ENSG00000185359.8	chr17	+	79651842	79651921	79650961	79651133	79652634	79652719	0.07900	0.00000	0.00006	included	K562	AQR
SE	HGS	ENSG00000185359.8	chr17	+	79668273	79668452	79668074	79668161	79668537	79669149	0.12700	0.00000	0.00025	included	K562	AGGF1
SE	HGS	ENSG00000185359.8	chr17	+	79668273	79668452	79668038	79668161	79668537	79669149	-0.14700	0.00000	0.00000	excluded	K562	HNRNPC
A3SS	HGS	ENSG00000185359.8	chr17	+	79668038	79668157	79668074	79668157	79667724	79667844	0.27000	0.00000	0.00021	longer	HepG2	U2AF2
A5SS	HGS	ENSG00000185359.8	chr17	+	79660873	79661080	79660873	79660995	79661844	79661883	0.12200	0.00000	0.00000	longer	K562	AQR
A5SS	HGS	ENSG00000185359.8	chr17	+	79657703	79657883	79657703	79657772	79658476	79658601	0.10300	0.00000	0.00001	longer	K562	AQR
SE	HGS	ENSG00000185359.8	chr17	+	79668273	79668452	79668038	79668161	79668537	79669149	-0.09900	0.00001	0.00089	excluded	HepG2	PTBP1

Showing 1 to 10 of 44 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

HGS

General Information

Functions

Localization

Domains (AlphaFold: HGS)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for HGS is not avaliable on ENCORE database.

45 proteins are bound to HGS RNA:

eCLIP assay for HGS is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for HGS is not available on ENCORE database.

117 RBPs can affect the gene expression of HGS :

The Knockdown/knockout RNA-Seq assay for HGS is not available on ENCORE database.

30 RBPs can affect the splicing of HGS :

The Knockdown/knockout RNA-Seq assay for HGS is not avaliable on ENCORE database.