FRG1

General Information

Gene Name       : FRG1
Gene ID             : ENSG00000109536.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FRG1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FRG1ENSG00000109536.1164.3165.8965.10ENCSR000AEF
HepG2FRG1ENSG00000109536.1121.4336.5729.00ENCSR985KAT
K562FRG1ENSG00000109536.1172.6787.3179.99ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FRG1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FRG1 RNA is bound by 16 proteins.  







eCLIP assay for FRG1 is not avaliable on ENCORE database.





16 proteins are bound to FRG1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4190873316190873361+3'-UTR,CDS,intron-Proximal5.1859515.81272K562UCHL5
chr4190873316190873358+3'-UTR,CDS,intron-Proximal4.376037.49468HepG2BCLAF1
chr4190873319190873360+3'-UTR,CDS3.192303.52026K562PUM1
chr4190873317190873350+3'-UTR,CDS3.358493.49777K562ZNF800
chr4190874222190874274+3'-UTR,CDS,intron-Distal,intron-Proximal3.895154.68902HepG2PPIG
chr4190876194190876220+3'-UTR,CDS,intron-Distal3.881555.77244K562UCHL5
chr4190876243190876288+3'-UTR,CDS,intron-Distal3.961595.06180HepG2BCLAF1
chr4190876246190876292+3'-UTR,CDS,intron-Distal4.624856.86924K562LIN28B
chr4190864356190864382+5'-UTR,CDS,intron-Proximal3.581819.18311K562UCHL5
chr4190864382190864427+5'-UTR,CDS4.6295816.75438K562UCHL5
chr4190862179190862228+5'-UTR,CDS,intron-Proximal3.498115.35682HepG2GRWD1
chr4190864356190864378+5'-UTR,CDS,intron-Proximal3.596999.86138K562ZNF622
chr4190862144190862178+5'-UTR,CDS3.720587.45042K562UCHL5
chr4190864357190864412+5'-UTR,CDS5.023405.37137HepG2BCLAF1
chr4190864355190864424+5'-UTR,CDS,intron-Proximal3.181996.16392K562GRWD1
chr4190862178190862228+5'-UTR,CDS,intron-Proximal4.1112614.65767K562UCHL5
chr4190864355190864394+5'-UTR,CDS,intron-Proximal3.033967.26020K562BUD13
chr4190862169190862227+5'-UTR,CDS,intron-Proximal3.8814210.16171K562GRWD1
chr4190862186190862226+5'-UTR,CDS4.244814.02380K562TRA2A
chr4190864354190864402+5'-UTR,CDS,intron-Proximal4.376334.02380K562TRA2A
chr4190878552190878570+CDS,intron-Proximal3.103136.80995K562ZNF622
chr4190878617190878675+CDS,intron-Proximal4.0780519.91400HepG2PRPF8
chr4190866727190866772+intron-Distal3.651774.91037K562EXOSC5
chr4190866187190866250+intron-Distal3.775063.24603K562KHSRP
chr4190866726190866776+intron-Distal3.902563.16986HepG2QKI
chr4190866893190866931+intron-Distal4.733814.80466K562EXOSC5
chr4190862336190862382+intron-Distal5.1421014.88923K562RBM15
chr4190862321190862336+intron-Distal,intron-Proximal5.278818.63033K562RBM15
chr4190866830190866875+intron-Distal5.279189.02435K562EXOSC5
chr4190883115190883165+intron-Proximal3.213175.77625K562RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FRG1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FRG1 is not available on ENCORE database.

  • 46 RBPs can affect the levels of FRG1.  








The Knockdown/knockout RNA-Seq assay for FRG1 is not available on ENCORE database.





46 RBPs can affect the gene expression of FRG1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FRG1ENSG00000109536.7916.92980557.392300.718005.756905.02180HepG2AKAP1
FRG1ENSG00000109536.7927.94440737.954400.330402.671201.91280HepG2CALR
FRG1ENSG00000109536.7247.88340320.95250-0.372702.197001.60330HepG2DNAJC2
FRG1ENSG00000109536.7235.64660440.90570-0.903807.038706.12410HepG2EIF2S1
FRG1ENSG00000109536.7909.91790680.289800.419502.336701.62470HepG2FIP1L1
FRG1ENSG00000109536.7247.08780326.93400-0.404001.874001.33060HepG2HNRNPA1
FRG1ENSG00000109536.7452.15990579.89900-0.359002.323401.65830HepG2IGF2BP1
FRG1ENSG00000109536.7331.69600463.55480-0.482902.680402.01440HepG2IGF2BP2
FRG1ENSG00000109536.7815.913201132.13870-0.472602.954402.09540HepG2LARP4
FRG1ENSG00000109536.7373.05510494.58120-0.406801.881101.35600HepG2MATR3
FRG1ENSG00000109536.7333.15130494.99880-0.571205.391304.59010HepG2PCBP1
FRG1ENSG00000109536.7389.58260503.66110-0.370502.741802.19610HepG2PTBP1
FRG1ENSG00000109536.7494.86500594.02270-0.263502.065401.53790HepG2PUM1
FRG1ENSG00000109536.7387.48350545.51730-0.493503.880803.15800HepG2QKI
FRG1ENSG00000109536.7351.16310495.07690-0.495503.478202.72900HepG2RBM25
FRG1ENSG00000109536.7408.94530560.54200-0.454903.702003.09390HepG2NELFE
FRG1ENSG00000109536.7891.640001252.94250-0.490802.036801.42590HepG2SF3B1
FRG1ENSG00000109536.7297.43820445.29200-0.582205.434504.70560HepG2SRSF9
FRG1ENSG00000109536.7831.192301233.36150-0.569302.778602.05310HepG2TARDBP
FRG1ENSG00000109536.7421.66340546.67670-0.374602.329001.53400HepG2TUFM
FRG1ENSG00000109536.71089.12990582.011900.904007.191506.18590HepG2U2AF1
FRG1ENSG00000109536.7522.62230715.62670-0.453405.346104.64860HepG2ZNF622
FRG1ENSG00000109536.72121.286103043.18760-0.520602.455201.63710K562BOP1
FRG1ENSG00000109536.72050.256302726.50540-0.411206.861805.08750K562CPEB4
FRG1ENSG00000109536.71928.755903235.96160-0.746505.404504.31620K562CPSF6
FRG1ENSG00000109536.71368.799401648.55970-0.268302.740201.53480K562DDX21
FRG1ENSG00000109536.72505.149303011.42560-0.265602.980202.00730K562EIF4G2
FRG1ENSG00000109536.72098.618402790.25610-0.411002.117501.32310K562FTO
FRG1ENSG00000109536.71648.504101233.700100.418102.564701.88890K562G3BP2
FRG1ENSG00000109536.72190.363503089.69090-0.496302.769101.97470K562GPKOW
FRG1ENSG00000109536.71082.166701341.30690-0.309702.677201.62250K562HNRNPA1
FRG1ENSG00000109536.72022.349302549.49850-0.334203.342402.16780K562HNRNPL
FRG1ENSG00000109536.71124.230201371.49700-0.286802.291301.45820K562MATR3
FRG1ENSG00000109536.71880.875003015.82230-0.681104.201003.10700K562METAP2
FRG1ENSG00000109536.71673.458502014.67620-0.267703.462302.56140K562MTPAP
FRG1ENSG00000109536.71716.711102238.47770-0.382908.872707.63820K562NSUN2
FRG1ENSG00000109536.71362.69680843.268500.692308.165506.87320K562PRPF8
FRG1ENSG00000109536.72958.671503424.27770-0.210902.172601.32060K562PUM2
FRG1ENSG00000109536.72756.012402197.568800.326602.579202.05070K562PUS1
FRG1ENSG00000109536.71091.29750859.020900.345202.158801.44200K562RPS19
FRG1ENSG00000109536.71831.101502208.81890-0.270603.078902.21920K562SF3A3
FRG1ENSG00000109536.71802.141702262.98380-0.328504.464003.30650K562SRPK2
FRG1ENSG00000109536.71092.042101308.97930-0.261401.970901.36180K562SRSF1
FRG1ENSG00000109536.7991.205701251.53630-0.336402.728701.68790K562SRSF4
FRG1ENSG00000109536.71439.012401200.552800.261302.113501.39450K562SYNCRIP
FRG1ENSG00000109536.7949.442401178.50000-0.311802.193501.36580K562TRIM56
FRG1ENSG00000109536.71868.117301196.101800.643104.624903.13720K562U2AF1
FRG1ENSG00000109536.71743.055002373.50600-0.445408.805307.61220K562UPF1
FRG1ENSG00000109536.71695.010002030.93300-0.260802.199201.41930K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FRG1 is not available on ENCORE database.





32 RBPs can affect the splicing of FRG1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.098000.000180.08871excludedK562TAF15
SEFRG1ENSG00000109536.7chr4+1908761911908763061908733161908734421908785521908786570.146000.000070.00227includedK562SRSF1
SEFRG1ENSG00000109536.7chr4+1908761911908763061908733161908734421908785521908786570.132000.000820.03228includedK562PRPF8
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.130000.000180.06904excludedK562XRN2
SEFRG1ENSG00000109536.7chr4+1908761911908763061908733161908734421908785521908786570.109000.000790.06452includedK562XRCC6
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.124000.000000.00111excludedK562FMR1
SEFRG1ENSG00000109536.7chr4+1908810001908810771908785521908786571908819021908819940.112000.000000.00001includedHepG2HNRNPK
SEFRG1ENSG00000109536.7chr4+1908630631908631591908620241908622261908643561908644270.085000.000030.00583includedHepG2DDX59
SEFRG1ENSG00000109536.7chr4+190863063190863159190862024190862226190864356190864427-0.067000.000420.03795excludedHepG2TBRG4
SEFRG1ENSG00000109536.7chr4+190881000190881077190878552190878657190881902190881994-0.120000.000000.00009excludedHepG2U2AF2
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.118000.000020.00907excludedK562METAP2
SEFRG1ENSG00000109536.7chr4+1908761911908763061908733161908734421908785521908786570.117000.001370.05049includedK562FXR1
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.163000.000000.00051excludedK562SUPV3L1
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.097000.000370.06088excludedK562NSUN2
SEFRG1ENSG00000109536.7chr4+190881000190881077190878552190878657190881902190881994-0.103000.000060.00578excludedHepG2SFPQ
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.109000.000150.06184excludedK562KHSRP
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.142000.000030.02052excludedK562UCHL5
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.272000.000070.01745excludedHepG2HNRNPA1
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.116000.000030.03682excludedK562SSB
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.159000.000000.00000excludedK562U2AF1
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.111000.000060.05544excludedK562DDX21
SEFRG1ENSG00000109536.7chr4+190881000190881077190878552190878657190881902190881994-0.106000.000120.02518excludedHepG2HNRNPUL1
SEFRG1ENSG00000109536.7chr4+1908794411908794881908785521908786571908819021908819940.063000.000010.01083includedK562PPIL4
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.213000.001540.09225excludedHepG2TIAL1
SEFRG1ENSG00000109536.7chr4+190881000190881077190878552190878657190881902190881994-0.095000.000110.02138excludedHepG2RBFOX2
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.111000.000060.01501excludedK562SRSF7
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.132000.000000.00025excludedK562UPF1
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.159000.000000.00000excludedK562CPSF6
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.143000.000000.00009excludedK562ZC3H8
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.113000.000070.03706excludedK562NCBP2
SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.226000.000600.02608excludedHepG2HNRNPC
A3SSFRG1ENSG00000109536.7chr4+1908842181908843431908842471908843431908829761908830870.070000.000000.00000longerK562AQR
A3SSFRG1ENSG00000109536.7chr4+1908829611908830391908829761908830391908819021908819940.054000.000000.00000longerK562AQR
MXEFRG1ENSG00000109536.7chr4+190864356190864427190873355190873442190862178190862226190876191190876305-0.073000.000000.000002includedK562PPIL4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FRG1 is not avaliable on ENCORE database.