PRDM10

General Information

Gene Name       : PRDM10
Gene ID             : ENSG00000170325.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PRDM10)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRDM10ENSG00000170325.142.722.972.85ENCSR000AEF
HepG2PRDM10ENSG00000170325.143.664.323.99ENCSR985KAT
K562PRDM10ENSG00000170325.143.534.514.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
PRDM10ENCAB724MBJPA5-82948UC2739260Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
PRDM10K562CRISPRBGKcLV17-39,BGKcLV17-40BGKcLV17-1,BGKcLV17-2NO CLEAR BAND ON THE POSITION,NotSatisfiedENCODE4
PRDM10HepG2CRISPRBGHcLV18-35,BGHcLV18-36BGHcLV18-1,BGHcLV18-2NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
PRDM10Product_ID: PA5-82948
Lot_ID: UC2739260
Source: Thermo Fisher
Target Name: PRDM10-human		 ThermoFisher_PA5-82948_UC2739260_PRDM10.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the PRDM10 specific antibody, PA5-82948. Lane 1 is 2.5% of five million whole cell lysate input. Lanes 2 and 3 are 50% of IP enrichment from five million whole cell lysate using normal IgG antibody and the PRDM10-specific antibody, PA5-82948. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.








RNA Targets

  • eCLIP assay for PRDM10 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRDM10 RNA is bound by 23 proteins.  







eCLIP assay for PRDM10 is not avaliable on ENCORE database.





23 proteins are bound to PRDM10 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11129770234129770297-3'-UTR,intron-Distal4.217703.31330K562UPF1
chr11129817011129817148-CDS,intron-Distal,intron-Proximal4.121686.12731K562UCHL5
chr11129817049129817129-CDS,intron-Distal,intron-Proximal3.427884.62864K562ZNF622
chr11129817039129817189-CDS,intron-Distal,intron-Proximal3.537218.31208HepG2PPIG
chr11129817044129817141-CDS,intron-Distal,intron-Proximal3.424064.88141HepG2GRWD1
chr11129871952129872064-intron-Distal3.200896.60422HepG2XRN2
chr11129871745129871813-intron-Distal3.115667.05513HepG2FAM120A
chr11129871915129872048-intron-Distal3.2717519.81704HepG2NKRF
chr11129871911129871982-intron-Distal5.145967.35452K562NONO
chr11129871919129872022-intron-Distal4.4881416.84344HepG2CSTF2T
chr11129871719129871838-intron-Distal5.187204.63925K562PHF6
chr11129860341129860422-intron-Distal3.506135.35827HepG2HNRNPC
chr11129871982129872018-intron-Distal4.108963.07008K562NONO
chr11129871931129872040-intron-Distal3.813158.57849HepG2GTF2F1
chr11129871837129871884-intron-Distal4.5470810.78166HepG2CSTF2T
chr11129871724129871800-intron-Distal3.3944912.63110HepG2CSTF2T
chr11129872111129872162-intron-Distal4.745524.04631HepG2XRN2
chr11129871800129871819-intron-Distal3.664748.50973HepG2CSTF2T
chr11129871543129871658-intron-Distal3.964496.77154K562NONO
chr11129844161129844249-intron-Distal6.2567817.93673HepG2PTBP1
chr11129871630129871734-intron-Distal3.640405.42728HepG2HNRNPM
chr11129871751129871860-intron-Distal3.496864.25123HepG2FUS
chr11129871668129871817-intron-Distal3.605005.29169K562HNRNPM
chr11129871427129871470-intron-Distal3.277113.11000HepG2HNRNPM
chr11129871742129871827-intron-Distal5.164386.16396K562NONO
chr11129872226129872299-intron-Distal4.223703.07008K562NONO
chr11129871762129871813-intron-Distal4.135343.48768HepG2KHSRP
chr11129844359129844414-intron-Distal4.036756.90077HepG2PTBP1
chr11129871735129871798-intron-Distal3.949096.40934HepG2HNRNPM
chr11129871921129871978-intron-Distal3.879208.72354HepG2SFPQ
chr11129871926129872051-intron-Distal3.023123.41531HepG2RBFOX2
chr11129871919129871961-intron-Distal4.434194.01285K562GEMIN5
chr11129872281129872348-intron-Distal4.663396.12434HepG2NCBP2
chr11129871819129871837-intron-Distal4.4593610.30165HepG2CSTF2T
chr11129816875129816989-intron-Distal,intron-Proximal3.474713.76553K562PRPF8
chr11129871924129872061-intron-Distal4.2223611.72703HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRDM10 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRDM10 is not available on ENCORE database.

  • 60 RBPs can affect the levels of PRDM10.  








The Knockdown/knockout RNA-Seq assay for PRDM10 is not available on ENCORE database.





60 RBPs can affect the gene expression of PRDM10 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRDM10ENSG00000170325.10241.94010408.91560-0.757204.392703.74370HepG2AKAP1
PRDM10ENSG00000170325.10342.85110466.57950-0.444502.527401.95230HepG2BOP1
PRDM10ENSG00000170325.10276.96770359.45210-0.376102.492201.69750HepG2DDX19B
PRDM10ENSG00000170325.10454.28470323.455800.489902.551001.98170HepG2EIF2S1
PRDM10ENSG00000170325.10552.60280357.434700.628504.183103.40170HepG2EIF4A3
PRDM10ENSG00000170325.10911.97850584.515600.641709.616408.60490HepG2ETF1
PRDM10ENSG00000170325.10356.61430234.025500.607603.081202.25480HepG2FUBP3
PRDM10ENSG00000170325.10531.02280355.234800.579903.802702.74860HepG2G3BP2
PRDM10ENSG00000170325.10569.24920360.829400.657604.646103.80200HepG2MAGOH
PRDM10ENSG00000170325.10262.83230362.83810-0.465202.002101.46080HepG2MATR3
PRDM10ENSG00000170325.10381.75000485.10870-0.345702.073701.41070HepG2NOL12
PRDM10ENSG00000170325.10425.91740334.173700.349902.233801.67780HepG2PCBP1
PRDM10ENSG00000170325.10348.93510463.08430-0.408301.885201.37940HepG2PUF60
PRDM10ENSG00000170325.10488.90060334.222400.548604.049403.24680HepG2RBM25
PRDM10ENSG00000170325.10498.04110326.692900.608203.060902.06950HepG2RPS10
PRDM10ENSG00000170325.10897.56980551.789600.7018011.3835010.55490HepG2SRFBP1
PRDM10ENSG00000170325.10684.44240479.077500.514605.799005.10830HepG2SSB
PRDM10ENSG00000170325.10818.31670406.527201.0092011.7760010.45270HepG2U2AF1
PRDM10ENSG00000170325.101073.42930434.667801.304104.711003.39850HepG2U2AF2
PRDM10ENSG00000170325.10397.63810544.95480-0.454703.663002.99020HepG2UTP3
PRDM10ENSG00000170325.10475.96200333.857200.511504.582703.75370HepG2ZC3H8
PRDM10ENSG00000170325.10793.13150537.945100.560006.475605.66000K562AGGF1
PRDM10ENSG00000170325.10870.06620559.773300.636207.101406.01400K562AKAP8L
PRDM10ENSG00000170325.10839.64750587.369000.515403.164902.18380K562ATP5C1
PRDM10ENSG00000170325.10351.99120469.60990-0.415902.168901.40300K562BOP1
PRDM10ENSG00000170325.10330.36510499.28600-0.595803.188102.34480K562CPSF6
PRDM10ENSG00000170325.10425.71670767.11850-0.8496014.1752012.81440K562DDX47
PRDM10ENSG00000170325.10812.93290602.249500.432703.400502.41610K562DKC1
PRDM10ENSG00000170325.10162.16030292.08560-0.849003.605602.44220K562EIF3A
PRDM10ENSG00000170325.10206.01150294.16810-0.513902.541301.77810K562EIF3G
PRDM10ENSG00000170325.10764.25160949.03720-0.312402.985002.01060K562EIF4G2
PRDM10ENSG00000170325.10393.23830522.25620-0.409402.401201.61170K562FIP1L1
PRDM10ENSG00000170325.10359.90400508.09680-0.497502.685801.84450K562FMR1
PRDM10ENSG00000170325.10311.64630608.94160-0.9664011.121609.58040K562GRSF1
PRDM10ENSG00000170325.10310.90540434.99020-0.484502.898802.29060K562HNRNPC
PRDM10ENSG00000170325.10302.31880429.57710-0.506802.620301.71670K562HNRNPM
PRDM10ENSG00000170325.10485.28650624.82560-0.364602.709201.82570K562HNRNPU
PRDM10ENSG00000170325.10280.51200708.04910-1.3358019.3169017.36150K562HSPD1
PRDM10ENSG00000170325.10924.51540593.999700.638102.895902.04950K562KIF1C
PRDM10ENSG00000170325.101009.17500665.438100.600707.160605.56750K562MBNL1
PRDM10ENSG00000170325.10322.25600465.28830-0.529903.067302.14330K562METAP2
PRDM10ENSG00000170325.10811.584601011.55820-0.317802.347801.31170K562MSI2
PRDM10ENSG00000170325.10428.30040638.08810-0.575106.570905.37280K562MTPAP
PRDM10ENSG00000170325.10769.38660466.429100.722005.444604.06120K562NAA15
PRDM10ENSG00000170325.10752.56580449.182000.744402.190701.33120K562PABPN1
PRDM10ENSG00000170325.10340.21510594.72890-0.805806.823605.51590K562PCBP3
PRDM10ENSG00000170325.10762.90080975.17220-0.354203.304301.73830K562PNPT1
PRDM10ENSG00000170325.10243.00520456.15360-0.908509.105407.68590K562POLR2G
PRDM10ENSG00000170325.10403.77430592.88410-0.554204.178703.14310K562PPIG
PRDM10ENSG00000170325.10351.39090507.51910-0.530404.258303.45120K562PTBP1
PRDM10ENSG00000170325.10845.003401101.48830-0.382403.881602.59750K562PUM1
PRDM10ENSG00000170325.10800.902001079.11770-0.430204.923203.63020K562PUM2
PRDM10ENSG00000170325.10900.09100555.019900.697407.272406.43890K562PUS1
PRDM10ENSG00000170325.10890.21720540.884000.718709.212308.15320K562RBM15
PRDM10ENSG00000170325.10335.87860512.10970-0.608504.508903.07710K562NELFE
PRDM10ENSG00000170325.10176.98700337.16350-0.929805.998604.79040K562RPS19
PRDM10ENSG00000170325.10798.89320410.649800.960003.890202.38820K562SF1
PRDM10ENSG00000170325.10513.86950699.57950-0.445104.124203.14020K562SF3A3
PRDM10ENSG00000170325.10834.65370471.821700.822803.318201.92440K562SNRNP200
PRDM10ENSG00000170325.10554.02660429.487900.367202.419901.66840K562U2AF2
PRDM10ENSG00000170325.10539.38850751.73150-0.478905.287804.32930K562UPF1
PRDM10ENSG00000170325.10547.37090668.89360-0.289302.358201.57230K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRDM10 is not available on ENCORE database.






No RBPs affect the alternative splcing events of PRDM10 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for PRDM10 is not avaliable on ENCORE database.