ECD

General Information

Gene Name       : ECD
Gene ID             : ENSG00000122882.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ECD)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ECDENSG00000122882.1036.5131.2033.85ENCSR000AEF
HepG2ECDENSG00000122882.1014.8226.0420.43ENCSR985KAT
K562ECDENSG00000122882.1036.8239.9838.40ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ECD is not avaliable on ENCORE database.



Proteins bound to RNA
  • ECD RNA is bound by 10 proteins.  







eCLIP assay for ECD is not avaliable on ENCORE database.





10 proteins are bound to ECD RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr107489436974894436-3'-UTR,CDS,intron-Distal3.122555.35431HepG2BCLAF1
chr107489918474899251-3'-UTR,CDS,intron-Distal3.176896.00907HepG2PPIG
chr107489906674899122-3'-UTR,CDS,intron-Distal,intron-Proximal4.170704.31428K562YBX3
chr107489451474894602-3'-UTR,CDS,intron-Distal,intron-Proximal3.675174.41130K562AQR
chr107490804574908080-3'-UTR,CDS,intron-Distal3.152333.02345K562ZNF622
chr107489404274894097-3'-UTR,intron-Distal3.811243.37631K562HNRNPL
chr107492026674920309-5'-UTR,CDS,intron-Distal3.518593.99908K562BUD13
chr107492359274923709-5'-UTR,CDS,intron-Distal,intron-Proximal3.843598.94272HepG2GRWD1
chr107492359974923657-CDS,intron-Distal3.331034.63109K562GRWD1
chr107492361474923661-CDS,intron-Distal3.792208.40792HepG2PPIG
chr107491413174914180-CDS,intron-Distal3.665304.09885HepG2BCLAF1
chr107492019674920229-CDS,intron-Distal4.512874.78529HepG2BCLAF1
chr107492360974923658-CDS,intron-Distal4.020697.28307HepG2BCLAF1
chr107489637474896462-intron-Distal,intron-Proximal4.027315.63763K562AQR
chr107490795974908030-intron-Distal,intron-Proximal4.469394.21433K562PRPF8
chr107492170774921788-intron-Distal4.694095.04868K562HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ECD is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ECD is not available on ENCORE database.

  • 70 RBPs can affect the levels of ECD.  








The Knockdown/knockout RNA-Seq assay for ECD is not available on ENCORE database.





70 RBPs can affect the gene expression of ECD :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ECDENSG00000122882.61353.45250653.727901.0498012.8047011.74850HepG2AKAP1
ECDENSG00000122882.6719.473601085.42720-0.593203.668702.99030HepG2BOP1
ECDENSG00000122882.6929.886401233.85660-0.408002.320101.43510HepG2CCAR1
ECDENSG00000122882.6729.53510604.108900.272102.270401.65910HepG2CKAP4
ECDENSG00000122882.6707.96440996.51660-0.493202.441701.78990HepG2CPSF6
ECDENSG00000122882.61019.96010870.496700.228501.923601.36880HepG2CELF1
ECDENSG00000122882.6719.75100935.90190-0.378904.287303.39720HepG2DAZAP1
ECDENSG00000122882.6918.85910626.231800.553004.265103.50250HepG2DDX3X
ECDENSG00000122882.6430.19360578.08270-0.426303.519602.76990HepG2DKC1
ECDENSG00000122882.6635.49650461.431900.461702.995201.84400HepG2EFTUD2
ECDENSG00000122882.6606.18540449.330500.431902.525201.65740HepG2EIF3D
ECDENSG00000122882.6410.97530571.51310-0.475702.615401.99300HepG2EIF4A3
ECDENSG00000122882.6600.92290884.55020-0.557804.774503.72240HepG2EIF4G2
ECDENSG00000122882.6887.816001079.54410-0.282102.791802.18850HepG2ETF1
ECDENSG00000122882.61285.39220818.759900.650605.107204.09100HepG2FIP1L1
ECDENSG00000122882.6587.61140419.998200.484403.359502.49770HepG2FUBP3
ECDENSG00000122882.6689.815601129.72570-0.711704.746603.92260HepG2GPKOW
ECDENSG00000122882.6279.27980653.85610-1.2273016.1063014.56610HepG2HNRNPC
ECDENSG00000122882.6762.78970934.36480-0.292702.738802.02480HepG2HNRNPF
ECDENSG00000122882.6731.93910541.591000.434402.895402.18030HepG2HNRNPK
ECDENSG00000122882.6632.60390852.50600-0.430405.131704.23660HepG2HNRNPL
ECDENSG00000122882.6779.604501078.10930-0.467701.912701.38100HepG2HNRNPLL
ECDENSG00000122882.6689.95900920.07920-0.415203.881003.03500HepG2IGF2BP1
ECDENSG00000122882.61007.801801302.39550-0.370001.999301.30120HepG2LARP4
ECDENSG00000122882.6879.82870580.033900.601004.446003.66390HepG2MATR3
ECDENSG00000122882.6681.26600470.258900.534702.452901.45980HepG2METAP2
ECDENSG00000122882.6888.91340662.479200.424103.157102.29580HepG2MSI2
ECDENSG00000122882.6776.599201099.32040-0.501402.581301.64900HepG2MTPAP
ECDENSG00000122882.6667.79440928.04350-0.474804.633203.64600HepG2NOL12
ECDENSG00000122882.6598.34880955.88000-0.675804.360003.42650HepG2NSUN2
ECDENSG00000122882.6658.76620550.843400.258001.920201.39910HepG2PCBP1
ECDENSG00000122882.6460.64790579.33330-0.330702.320801.63910HepG2PPIL4
ECDENSG00000122882.6602.41860752.25900-0.320502.712901.94570HepG2PRPF4
ECDENSG00000122882.6681.83210510.907600.416302.674301.88010HepG2PRPF8
ECDENSG00000122882.6752.56580560.550800.424904.457303.79880HepG2PTBP1
ECDENSG00000122882.6493.30260885.92530-0.8447010.820709.74550HepG2PUF60
ECDENSG00000122882.61209.55170902.294400.422704.998204.35360HepG2RBM22
ECDENSG00000122882.6729.04490550.920400.404103.156102.44090HepG2RBM25
ECDENSG00000122882.6775.234601006.59170-0.376803.050702.33910HepG2RPLP0
ECDENSG00000122882.6572.40880437.228400.388602.435101.85450HepG2RPS19
ECDENSG00000122882.6660.08050505.405600.385102.207301.49760HepG2RRP9
ECDENSG00000122882.61113.23200783.281000.507103.095002.38160HepG2SF3A3
ECDENSG00000122882.6797.287801067.17100-0.420602.185001.55350HepG2SF3B1
ECDENSG00000122882.6684.64990849.52800-0.311302.647501.95920HepG2SLBP
ECDENSG00000122882.61205.439901019.100100.242202.356401.88210HepG2SRFBP1
ECDENSG00000122882.61259.36090609.104401.0478023.6732022.58640HepG2SRSF1
ECDENSG00000122882.6749.11230917.99460-0.293302.750102.05560HepG2SRSF7
ECDENSG00000122882.6710.97300884.80570-0.315603.074802.54040HepG2SSB
ECDENSG00000122882.6790.860801050.56680-0.409702.131501.48320HepG2TARDBP
ECDENSG00000122882.6516.21640636.78360-0.302802.333301.80650HepG2TRIM56
ECDENSG00000122882.61304.26020700.298200.897107.991706.92620HepG2U2AF1
ECDENSG00000122882.61583.17060738.960401.099103.747002.58910HepG2U2AF2
ECDENSG00000122882.6404.80360694.64960-0.7791011.9444010.67760HepG2UPF1
ECDENSG00000122882.6965.37810670.658300.525405.555604.75530HepG2UTP3
ECDENSG00000122882.6466.34690648.88980-0.476602.549701.85240HepG2XRN2
ECDENSG00000122882.62724.341102127.661600.356503.159602.54020K562AQR
ECDENSG00000122882.61517.299201927.10810-0.344902.139601.37900K562BOP1
ECDENSG00000122882.63127.266202414.158300.373306.972406.00340K562DDX47
ECDENSG00000122882.62214.097501846.393500.261902.973002.05940K562DKC1
ECDENSG00000122882.61409.009301756.70610-0.318203.750002.93510K562EIF2S2
ECDENSG00000122882.61402.85380872.759900.684604.285003.00670K562EIF3A
ECDENSG00000122882.62373.613202998.76030-0.337304.591803.39350K562EIF4G2
ECDENSG00000122882.61414.030601767.08660-0.321602.194101.38430K562FTO
ECDENSG00000122882.61327.087901114.095700.252302.369401.80130K562FXR1
ECDENSG00000122882.61454.721101956.39580-0.427504.496103.48830K562GPKOW
ECDENSG00000122882.61817.884902341.03090-0.364903.814802.93160K562GRSF1
ECDENSG00000122882.6566.327101498.79160-1.4041034.7686032.73290K562HNRNPC
ECDENSG00000122882.61789.713302181.70110-0.285702.505601.50460K562HNRNPL
ECDENSG00000122882.62014.163401669.559500.270602.804301.90390K562HNRNPU
ECDENSG00000122882.62450.787902039.936100.264602.219801.42040K562MBNL1
ECDENSG00000122882.61425.801901752.54020-0.297704.002203.04510K562MTPAP
ECDENSG00000122882.61647.826601947.30180-0.240903.755602.90180K562NSUN2
ECDENSG00000122882.61667.741401287.295000.373503.328402.25530K562PCBP2
ECDENSG00000122882.61603.560701071.962100.580906.471105.32260K562PRPF8
ECDENSG00000122882.61703.934501405.578700.277602.180101.57920K562PTBP1
ECDENSG00000122882.62536.064503271.93020-0.367603.502202.58600K562PUF60
ECDENSG00000122882.62715.320303409.93420-0.328604.383003.16850K562PUM2
ECDENSG00000122882.62291.720401701.667500.429404.426603.76250K562PUS1
ECDENSG00000122882.61989.344501658.017400.262702.670702.08670K562RBM15
ECDENSG00000122882.62090.627401092.128100.9367013.3508011.53130K562RPS19
ECDENSG00000122882.61451.777901211.499100.260902.129901.38160K562SF3B4
ECDENSG00000122882.61117.041001345.22890-0.268202.119401.41080K562TIA1
ECDENSG00000122882.61495.472601129.338500.405002.815401.71210K562U2AF1
ECDENSG00000122882.61681.983901166.403100.528007.440806.12740K562U2AF2
ECDENSG00000122882.61744.524102064.75970-0.243103.209702.43870K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ECD is not available on ENCORE database.





23 RBPs can affect the splicing of ECD :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.252000.000000.00056excludedK562SMNDC1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.186000.000030.02031excludedK562XRN2
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.324000.000000.00000excludedK562AKAP8L
SEECDENSG00000122882.6chr10-749060337490611974899388748994957490803374908162-0.057000.000010.00020excludedK562AQR
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.090000.000910.01131excludedK562AQR
SEECDENSG00000122882.6chr10-749140137491420674912103749121797491603274916211-0.065000.000010.00029excludedK562AQR
SEECDENSG00000122882.6chr10-748977607489782874896461748966767489906674899253-0.084000.000010.00013excludedK562AQR
SEECDENSG00000122882.6chr10-7492349074923708749201917492030974927623749278220.162000.000010.00066includedK562FXR1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927822-0.216000.000030.05950excludedK562EWSR1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.188000.000030.00470excludedK562SUPV3L1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.407000.000000.00000excludedK562PUS1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.320000.000000.00004excludedK562U2AF1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927822-0.225000.000020.03859excludedK562DDX6
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927822-0.188000.000080.07421excludedK562DDX21
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.244000.000000.00276excludedK562ZRANB2
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927822-0.259000.000290.02737excludedK562HNRNPUL1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.278000.000000.00012excludedK562SRSF7
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.278000.000150.00799excludedK562UTP18
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.311000.000000.00000excludedK562RBM15
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.368000.000000.00000excludedK562AGGF1
SEECDENSG00000122882.6chr10-748977607489782874896461748966767489906674899253-0.115000.000220.00835excludedK562AGGF1
SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927822-0.239000.000000.00943excludedK562DDX3X
A3SSECDENSG00000122882.6chr10-7489906674899303748990667489925374899388748994950.088000.000000.00000longerK562AQR
A3SSECDENSG00000122882.6chr10-7491205074912238749120507491217974914013749141530.085000.000000.00000longerK562AQR
A3SSECDENSG00000122882.6chr10-7489938874899592748993887489949574906033749061190.076000.000000.00000longerK562AQR
A3SSECDENSG00000122882.6chr10-7491632574916541749163257491641374920191749203090.058000.000000.00000longerK562AQR
A3SSECDENSG00000122882.6chr10-7489646174896705748964617489667674897760748977930.103000.000000.00000longerK562AQR
A3SSECDENSG00000122882.6chr10-7491603274916254749160327491621174916325749164130.074000.000000.00000longerK562AQR
A3SSECDENSG00000122882.6chr10-7491401374914227749140137491420674916032749162110.234000.000000.00000longerK562AQR
MXEECDENSG00000122882.6chr10-7491205074912179749140137491420674908033749081627491603274916211-0.127000.000860.068422includedK562HNRNPL
MXEECDENSG00000122882.6chr10-74912050749121797491401374914206749080337490816274916032749162110.156000.000230.006381includedK562DROSHA
MXEECDENSG00000122882.6chr10-7491632574916413749201917492030974916032749162117492349074923708-0.087000.000070.005752includedK562LIN28B
MXEECDENSG00000122882.6chr10-74912050749121797491401374914227749080337490816274916032749162110.143000.000000.000001includedK562AQR
MXEECDENSG00000122882.6chr10-7491194974912179749140137491420674908033749081627491603274916211-0.090000.000000.000022includedK562AQR
MXEECDENSG00000122882.6chr10-74912050749121797491401374914206749080337490816274916032749162110.403000.000520.011681includedHepG2HNRNPUL1
MXEECDENSG00000122882.6chr10-74912050749121797491401374914206749080337490816274916032749162110.124000.002080.058791includedK562DDX55
MXEECDENSG00000122882.6chr10-7491205074912179749140137491420674908033749081627491603274916211-0.080000.005180.085132includedK562FXR2
MXEECDENSG00000122882.6chr10-74912050749121797491401374914206749080337490816274916032749162110.152000.005930.069801includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ECD is not avaliable on ENCORE database.