FAM222B

General Information

Gene Name       : FAM222B
Gene ID             : ENSG00000173065.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM222B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM222BENSG00000173065.137.849.648.74ENCSR000AEF
HepG2FAM222BENSG00000173065.1310.227.969.09ENCSR985KAT
K562FAM222BENSG00000173065.1324.9623.2524.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAM222B is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM222B RNA is bound by 23 proteins.  







eCLIP assay for FAM222B is not avaliable on ENCORE database.





23 proteins are bound to FAM222B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr172708492827085002-3'-UTR,intron-Distal3.734195.11028HepG2PCBP2
chr172708575827085769-3'-UTR,CDS,intron-Distal6.5300622.11853K562RBM15
chr172708631127086426-3'-UTR,CDS,intron-Distal,intron-Proximal4.524745.90266HepG2IGF2BP1
chr172708379527083873-3'-UTR,intron-Distal3.569213.57062K562IGF2BP1
chr172708448627084535-3'-UTR,intron-Distal3.360574.30970K562IGF2BP2
chr172708669327086754-3'-UTR,CDS,intron-Distal,intron-Proximal4.452985.46339K562IGF2BP2
chr172708481827084890-3'-UTR,intron-Distal4.381414.83729K562ILF3
chr172708565827085692-3'-UTR,CDS,intron-Distal3.152333.07653K562ZNF622
chr172708650027086557-3'-UTR,CDS,intron-Distal,intron-Proximal3.380344.30970K562IGF2BP2
chr172708603427086061-3'-UTR,CDS,intron-Distal4.004593.48187K562RBM15
chr172708447027084557-3'-UTR,intron-Distal3.381653.84715HepG2HNRNPK
chr172708618027086224-3'-UTR,CDS,intron-Distal,intron-Proximal4.522418.71170K562RBM15
chr172709361727093727-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.194925.07098K562DDX3X
chr172708580827085833-3'-UTR,CDS,intron-Distal4.594885.17013K562RBM15
chr172708447027084542-3'-UTR,intron-Distal3.908948.14483HepG2PCBP2
chr172708576927085798-3'-UTR,CDS,intron-Distal4.280863.73926K562RBM15
chr172708572127085758-3'-UTR,CDS,intron-Distal5.7160525.42014K562RBM15
chr172708610327086152-3'-UTR,CDS,intron-Distal5.4948423.47898K562RBM15
chr172708617227086226-3'-UTR,CDS,intron-Distal,intron-Proximal3.427874.54958K562IGF2BP2
chr172708482827084890-3'-UTR,intron-Distal3.686234.03740HepG2PCBP2
chr172708625827086301-3'-UTR,CDS,intron-Distal,intron-Proximal3.359485.89284K562RBM15
chr172708616827086232-3'-UTR,CDS,intron-Distal,intron-Proximal3.207803.85040HepG2IGF2BP1
chr172708657427086628-3'-UTR,CDS,intron-Distal,intron-Proximal5.102797.93248K562RBM15
chr172708447427084585-3'-UTR,intron-Distal3.679113.72310K562HNRNPK
chr172708650727086548-3'-UTR,CDS,intron-Distal,intron-Proximal3.953546.98960K562RBM15
chr172708591027085973-3'-UTR,CDS,intron-Distal3.985109.87361K562RBM15
chr172713935127139544-5'-UTR,intron-Distal,intron-Proximal3.477598.25655K562XRN2
chr172716969827169749-5'-UTR,intron-Distal,intron-Proximal4.136173.69238K562GTF2F1
chr172713935227139408-5'-UTR,intron-Distal3.969575.07081HepG2XPO5
chr172713924227139312-5'-UTR,intron-Distal,intron-Proximal4.740325.84317K562XRN2
chr172716892227169116-intron-Distal3.907285.82781HepG2KHSRP
chr172710615727106254-intron-Distal4.068324.27460K562HNRNPM
chr172711997827120095-intron-Distal3.656407.08738K562RBFOX2
chr172712251327122612-intron-Distal4.468224.33299K562ILF3
chr172712000527120077-intron-Distal3.115566.54858HepG2ILF3
chr172716949727169605-intron-Distal5.214128.56484HepG2PRPF4
chr172715411827154166-intron-Distal3.445886.34973K562ILF3
chr172713953527139609-intron-Distal,intron-Proximal4.433455.09405K562NONO
chr172712021727120268-intron-Distal3.523315.09850K562ILF3
chr172716951827169574-intron-Distal3.068533.68839K562KHSRP
chr172716950827169567-intron-Distal3.5229410.17627K562EFTUD2
chr172709790027098001-intron-Distal3.333914.05663K562HNRNPL
chr172716949127169563-intron-Distal4.620746.03756HepG2FAM120A
chr172711999727120079-intron-Distal5.2998316.10442K562ILF3
chr172713994327140027-intron-Distal3.175745.64759K562NONO
chr172713953027139633-intron-Distal,intron-Proximal5.411837.96764HepG2XPO5
chr172712502727125087-intron-Distal3.077763.64839HepG2HNRNPC
chr172713963127139698-intron-Distal3.307923.84859K562NONO
chr172709506627095168-intron-Distal4.337123.57432K562NONO
chr172716945927169571-intron-Distal4.8060911.38030K562GTF2F1
chr172716115027161201-intron-Distal3.805903.00997K562TAF15
chr172716957127169639-intron-Distal4.471098.91844K562GTF2F1
chr172716458227164638-intron-Distal3.002123.98838K562ILF3
chr172716892827169017-intron-Distal4.0658812.86756K562KHSRP
chr172713964427139727-intron-Distal3.059525.62981HepG2NKRF
chr172716951427169620-intron-Distal3.170444.59315HepG2GTF2F1
chr172715045427150554-intron-Distal3.581514.09735K562ILF3
chr172716957427169636-intron-Distal4.152834.76003K562KHSRP
chr172716957127169617-intron-Distal4.158353.59342K562CSTF2T
chr172713972727139802-intron-Distal3.856815.35442HepG2NKRF
chr172716486827164970-intron-Distal4.116903.77875HepG2ILF3
chr172716946727169587-intron-Distal4.559384.10339HepG2CSTF2T
chr172716339927163464-intron-Distal3.021793.14580K562ILF3
chr172711747627117595-intron-Distal,intron-Proximal5.048049.04304K562KHSRP
chr172716901727169216-intron-Distal3.1859613.86088K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM222B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM222B is not available on ENCORE database.

  • 110 RBPs can affect the levels of FAM222B.  








The Knockdown/knockout RNA-Seq assay for FAM222B is not available on ENCORE database.





110 RBPs can affect the gene expression of FAM222B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM222BENSG00000173065.9604.63550466.005800.375602.347301.35600HepG2AATF
FAM222BENSG00000173065.91087.027001391.75870-0.356502.728701.79170HepG2ABCF1
FAM222BENSG00000173065.91037.15620676.074500.6173010.804209.76630HepG2ACO1
FAM222BENSG00000173065.9842.66110679.269000.310902.740801.97700HepG2AKAP8L
FAM222BENSG00000173065.91175.22770926.373000.343203.884703.09650HepG2AUH
FAM222BENSG00000173065.91987.103001525.304700.381502.847402.24070HepG2BOP1
FAM222BENSG00000173065.91318.208301042.461300.338502.465501.30450HepG2BUD13
FAM222BENSG00000173065.91266.309001018.747800.313702.821102.04220HepG2CALR
FAM222BENSG00000173065.9829.70240675.949300.295602.820502.15010HepG2CKAP4
FAM222BENSG00000173065.91652.454601145.796200.528206.057004.46410HepG2CPSF7
FAM222BENSG00000173065.9564.79790710.04240-0.330202.489201.52680HepG2YBX3
FAM222BENSG00000173065.9213.68060342.46620-0.680504.326903.01470HepG2CSTF2
FAM222BENSG00000173065.9460.24340625.28200-0.442104.695403.64700HepG2DDX19B
FAM222BENSG00000173065.9953.18240711.055700.422702.474001.38320HepG2DDX1
FAM222BENSG00000173065.91464.93790692.269201.0813015.8831014.51080HepG2DDX3X
FAM222BENSG00000173065.9704.53990532.003100.405102.933301.53860HepG2DDX52
FAM222BENSG00000173065.91118.40090545.179701.0365011.4696010.02410HepG2DDX55
FAM222BENSG00000173065.92398.364601590.198800.592703.334302.26340HepG2DDX59
FAM222BENSG00000173065.9488.37170646.82570-0.405403.475702.72960HepG2DKC1
FAM222BENSG00000173065.9957.47830697.240400.457505.241204.30220HepG2DNAJC21
FAM222BENSG00000173065.9983.08860691.037100.508502.816202.15930HepG2DNAJC2
FAM222BENSG00000173065.91174.03330571.665901.0381014.0216012.75490HepG2EIF2S1
FAM222BENSG00000173065.91033.98230515.129001.0051012.6067010.82970HepG2EIF3D
FAM222BENSG00000173065.91528.80280615.222701.3131016.5374014.95470HepG2EIF4B
FAM222BENSG00000173065.9933.066301205.39290-0.369503.080901.93240HepG2ESF1
FAM222BENSG00000173065.92990.039201405.269901.0892011.4790010.06480HepG2FIP1L1
FAM222BENSG00000173065.9328.49040453.76670-0.466102.542901.32340HepG2FKBP4
FAM222BENSG00000173065.9937.75940637.671000.556304.427203.56610HepG2FXR1
FAM222BENSG00000173065.9649.36640471.234500.462502.992601.93240HepG2GNB2L1
FAM222BENSG00000173065.9810.52640645.470800.328403.063402.04020HepG2HDGF
FAM222BENSG00000173065.9885.93570717.744700.303602.828601.88570HepG2HNRNPA2B1
FAM222BENSG00000173065.9877.21550601.006100.545504.153103.34070HepG2IGF2BP2
FAM222BENSG00000173065.91029.86990564.305000.867803.680002.54440HepG2IGF2BP3
FAM222BENSG00000173065.91071.57320794.489100.431506.811505.71180HepG2ILF2
FAM222BENSG00000173065.9630.34200461.701800.449103.008101.82390HepG2LARP7
FAM222BENSG00000173065.9996.68090641.403600.635805.014304.18720HepG2MATR3
FAM222BENSG00000173065.9948.956501544.82520-0.703003.734502.59660HepG2MTPAP
FAM222BENSG00000173065.91252.70760656.462000.9322011.219109.98660HepG2NCBP2
FAM222BENSG00000173065.9773.105301343.25870-0.797005.385504.35840HepG2NSUN2
FAM222BENSG00000173065.9899.84410613.590400.552302.646001.78210HepG2PABPC1
FAM222BENSG00000173065.91141.59610584.391100.9659012.1844010.69940HepG2PABPC4
FAM222BENSG00000173065.9939.88110769.897900.287702.558601.74140HepG2PARN
FAM222BENSG00000173065.91023.44590603.189800.762708.952707.96260HepG2PCBP1
FAM222BENSG00000173065.91382.34040613.808501.1712031.9518030.49970HepG2PTBP1
FAM222BENSG00000173065.91221.61920784.757100.6384014.4539013.32020HepG2PUM1
FAM222BENSG00000173065.91351.56480688.628900.9727012.5273011.37940HepG2PUS1
FAM222BENSG00000173065.9903.07260664.684000.442104.380403.62090HepG2QKI
FAM222BENSG00000173065.91742.22940567.956801.6170018.5197016.85260HepG2RAVER1
FAM222BENSG00000173065.91878.54410888.981301.0793015.7563014.72630HepG2RBM22
FAM222BENSG00000173065.9862.60400603.275800.515803.803303.02210HepG2RBM25
FAM222BENSG00000173065.9652.82950452.100300.530002.957801.85900HepG2RCC2
FAM222BENSG00000173065.9879.74650683.076500.364903.519702.92540HepG2NELFE
FAM222BENSG00000173065.91562.776701197.004200.384602.171301.55740HepG2RPLP0
FAM222BENSG00000173065.9928.97650501.302900.8899012.4919011.29860HepG2RPS19
FAM222BENSG00000173065.9728.80160524.136300.475503.075801.94100HepG2RPS5
FAM222BENSG00000173065.9707.70640415.956300.766605.974704.86600HepG2RRP9
FAM222BENSG00000173065.9698.56010503.041100.473603.250002.22730HepG2SERBP1
FAM222BENSG00000173065.91623.062001085.949700.579703.870603.06660HepG2SF3A3
FAM222BENSG00000173065.9885.04660638.981700.469905.535204.74840HepG2SF3B4
FAM222BENSG00000173065.91134.70160807.780000.490206.706805.77440HepG2SMN1
FAM222BENSG00000173065.9867.75410579.638800.582003.794402.65990HepG2SMNDC1
FAM222BENSG00000173065.91405.52650710.255600.984603.423601.92840HepG2SNRNP200
FAM222BENSG00000173065.91349.820601004.066700.426806.669605.98530HepG2SRFBP1
FAM222BENSG00000173065.93218.057601613.406900.996009.161607.25960HepG2SRSF3
FAM222BENSG00000173065.9846.06900542.655600.6406010.179509.23730HepG2SRSF9
FAM222BENSG00000173065.9574.13340871.75900-0.602508.821508.00650HepG2SSB
FAM222BENSG00000173065.91166.71870830.096300.491007.976407.01100HepG2SUCLG1
FAM222BENSG00000173065.91183.70100948.632300.319302.213501.36950HepG2SUPT6H
FAM222BENSG00000173065.9442.39630599.59650-0.438703.459202.84390HepG2TAF15
FAM222BENSG00000173065.9238.60210363.74210-0.608302.912701.89180HepG2TFIP11
FAM222BENSG00000173065.9712.95370550.860800.372002.919802.06290HepG2TIA1
FAM222BENSG00000173065.9542.72850755.82580-0.477804.357203.75860HepG2TIAL1
FAM222BENSG00000173065.9920.49500762.520300.271502.453001.91490HepG2TRIM56
FAM222BENSG00000173065.91594.751701201.935600.407902.964502.31530HepG2U2AF1
FAM222BENSG00000173065.93004.70640828.130201.859209.525107.58080HepG2U2AF2
FAM222BENSG00000173065.91075.11740764.500300.491803.422202.49040HepG2UBE2L3
FAM222BENSG00000173065.9623.95860963.07270-0.626208.789807.66380HepG2UPF1
FAM222BENSG00000173065.91974.25840929.806801.086209.452508.45320HepG2UTP3
FAM222BENSG00000173065.9853.13310624.699900.449502.339501.36610HepG2XRCC6
FAM222BENSG00000173065.9383.89770534.22940-0.476702.768702.04350HepG2XRN2
FAM222BENSG00000173065.9666.372001005.13090-0.5930010.205009.05170HepG2ZC3H8
FAM222BENSG00000173065.91573.212901059.193800.5706013.7385012.75260HepG2ZNF622
FAM222BENSG00000173065.91157.89000896.024000.369803.023001.78250K562AARS
FAM222BENSG00000173065.9969.358701402.89080-0.533309.133008.17770K562AGGF1
FAM222BENSG00000173065.91148.580401541.45290-0.424404.232702.96230K562AKAP8
FAM222BENSG00000173065.91090.933001459.74390-0.420204.087703.29140K562AKAP8L
FAM222BENSG00000173065.91784.039001345.507500.406903.244502.61860K562AQR
FAM222BENSG00000173065.91480.04870946.927700.644207.099705.21480K562CCAR1
FAM222BENSG00000173065.91385.949002260.51510-0.7058013.6100011.55880K562CELF1
FAM222BENSG00000173065.9868.54500599.879600.533805.339103.82600K562DDX3X
FAM222BENSG00000173065.92737.633902184.313900.325602.108301.52680K562DDX47
FAM222BENSG00000173065.91503.774801060.141900.504204.815502.95910K562DHX30
FAM222BENSG00000173065.91300.356901570.96170-0.272702.978102.06220K562DKC1
FAM222BENSG00000173065.9843.30580658.846900.356003.329601.99120K562EIF2S1
FAM222BENSG00000173065.91353.29650963.166000.490502.565801.60060K562EIF3A
FAM222BENSG00000173065.91316.19920768.310200.776507.858205.96420K562EIF3D
FAM222BENSG00000173065.9982.74360626.700300.648907.178005.86190K562EIF4A3
FAM222BENSG00000173065.9829.12790564.353000.554906.599904.68840K562EIF4B
FAM222BENSG00000173065.91033.05530651.737500.6645010.081009.00990K562FXR1
FAM222BENSG00000173065.91267.927701550.50040-0.290302.290301.59940K562GRSF1
FAM222BENSG00000173065.91353.12300980.206300.465004.819504.05240K562HNRNPC
FAM222BENSG00000173065.91163.01550875.424100.409703.633302.30910K562HNRNPF
FAM222BENSG00000173065.91609.005801973.85780-0.294802.441501.45610K562HNRNPL
FAM222BENSG00000173065.91468.713501136.549000.369804.274803.15580K562HNRNPU
FAM222BENSG00000173065.91593.943802423.15840-0.604302.147301.44350K562HSPD1
FAM222BENSG00000173065.91025.521901549.24970-0.595205.368104.13840K562KIF1C
FAM222BENSG00000173065.9863.46040671.010900.363702.855401.91760K562MATR3
FAM222BENSG00000173065.91223.363701735.53750-0.504506.090304.63860K562MBNL1
FAM222BENSG00000173065.9865.727201216.47760-0.490703.195902.23380K562NAA15
FAM222BENSG00000173065.91551.958202011.00230-0.373803.191601.57690K562NOL12
FAM222BENSG00000173065.91078.38040653.314400.7229010.463709.23130K562PTBP1
FAM222BENSG00000173065.9921.150801447.86250-0.652407.342806.50410K562PUS1
FAM222BENSG00000173065.91102.863901410.56060-0.355003.924003.23500K562RBM15
FAM222BENSG00000173065.91358.54460802.000900.760309.069107.27100K562RCC2
FAM222BENSG00000173065.91105.32500742.457700.574003.174802.09230K562RPS3
FAM222BENSG00000173065.91839.027001199.269100.616707.883106.09460K562SAFB
FAM222BENSG00000173065.9550.88830908.80120-0.722202.835101.61170K562SF1
FAM222BENSG00000173065.92246.431401810.938200.310803.847102.89380K562SF3A3
FAM222BENSG00000173065.9604.43320464.027700.381302.868401.99700K562SF3B4
FAM222BENSG00000173065.91118.97630760.261800.557505.610504.00060K562SRFBP1
FAM222BENSG00000173065.9886.50570640.496200.468804.272603.39970K562SRSF1
FAM222BENSG00000173065.91097.81130716.546900.615403.982002.68570K562SRSF4
FAM222BENSG00000173065.9916.11200676.069800.438302.847801.81580K562SUPV3L1
FAM222BENSG00000173065.9961.17940648.158700.568405.234604.24450K562TARDBP
FAM222BENSG00000173065.91131.04400845.324400.420002.961601.99100K562TIAL1
FAM222BENSG00000173065.9599.63040446.702600.424702.259001.53420K562U2AF2
FAM222BENSG00000173065.91105.192401515.65200-0.455604.619403.46230K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM222B is not available on ENCORE database.





3 RBPs can affect the splicing of FAM222B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM222BENSG00000173065.9chr17-2711739527117461270936602709372527161310271613440.699000.000010.00033includedHepG2U2AF2
SEFAM222BENSG00000173065.9chr17-2716131027161344270936032709372527169699271698570.695000.000200.05998includedHepG2DROSHA
A3SSFAM222BENSG00000173065.9chr17-2708684527086986270868452708689427093603270938000.111000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM222B is not avaliable on ENCORE database.