USP21

General Information

Gene Name       : USP21
Gene ID             : ENSG00000143258.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: USP21)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878USP21ENSG00000143258.1511.0812.8211.95ENCSR000AEF
HepG2USP21ENSG00000143258.1520.5821.8821.23ENCSR985KAT
K562USP21ENSG00000143258.1532.4235.2533.84ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for USP21 is not avaliable on ENCORE database.



Proteins bound to RNA
  • USP21 RNA is bound by 15 proteins.  







eCLIP assay for USP21 is not avaliable on ENCORE database.





15 proteins are bound to USP21 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1161135378161135478+3'-UTR4.104684.08723K562HNRNPK
chr1161135386161135489+3'-UTR6.10371400.00000K562PUM2
chr1161130363161130451+3'-UTR,5'-UTR,CDS,intron-Proximal3.634687.14018K562BUD13
chr1161130360161130432+3'-UTR,5'-UTR,CDS,intron-Proximal4.1621310.90247K562SF3B4
chr1161130377161130445+3'-UTR,5'-UTR,CDS,intron-Proximal5.419527.65816K562SMNDC1
chr1161129323161129472+5'-UTR,intron-Proximal3.026143.17655HepG2NCBP2
chr1161133687161133777+CDS,intron-Proximal4.261604.94878HepG2GRWD1
chr1161133267161133371+CDS,intron-Proximal4.074996.19659HepG2AQR
chr1161133928161134000+CDS,intron-Proximal4.328397.98209HepG2U2AF2
chr1161134312161134363+CDS,intron-Proximal4.775875.55733K562BUD13
chr1161132356161132463+CDS,intron-Proximal3.262187.06578HepG2U2AF2
chr1161134278161134359+CDS,intron-Proximal5.239726.47067K562SF3B4
chr1161133310161133358+CDS,intron-Proximal4.120285.83621K562AQR
chr1161132131161132217+CDS,intron-Proximal3.9929414.40440HepG2PRPF8
chr1161134775161134857+CDS,intron-Proximal3.893066.38859K562EFTUD2
chr1161131799161131848+CDS,intron-Proximal4.012855.47926K562AQR
chr1161133346161133407+CDS3.403394.99842HepG2PPIG
chr1161130508161130556+CDS4.101913.28461K562BUD13
chr1161131027161131054+CDS,intron-Proximal6.1530715.31585K562AQR
chr1161133667161133712+CDS,intron-Proximal3.727945.24452HepG2PPIG
chr1161130795161130873+CDS,intron-Proximal5.8247914.27145K562RBM15
chr1161130501161130556+CDS4.206236.37184K562RBM15
chr1161132757161132809+CDS3.551123.86355HepG2PPIG
chr1161134115161134212+intron-Distal,intron-Proximal4.4355710.62186K562RBFOX2
chr1161133023161133074+intron-Distal4.253896.48405K562AQR
chr1161129549161129608+intron-Distal,intron-Proximal3.427894.88100K562AQR
chr1161134413161134539+intron-Distal,intron-Proximal4.569829.44509HepG2U2AF2
chr1161134044161134110+intron-Proximal3.474815.89182K562EFTUD2
chr1161132864161132926+intron-Proximal3.773836.06472K562AQR
chr1161131054161131072+intron-Proximal5.2845914.28850K562AQR
chr1161129468161129549+intron-Proximal5.2497013.23057K562AQR
chr1161132187161132223+intron-Proximal3.357384.28285K562AQR
chr1161134251161134294+intron-Proximal4.643394.38235HepG2RBM5
chr1161132180161132187+intron-Proximal3.784594.52312K562AQR
chr1161131076161131090+intron-Proximal3.860593.04871K562AQR
chr1161129494161129548+intron-Proximal3.016953.41438K562BUD13
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for USP21 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for USP21 is not available on ENCORE database.

  • 34 RBPs can affect the levels of USP21.  








The Knockdown/knockout RNA-Seq assay for USP21 is not available on ENCORE database.





34 RBPs can affect the gene expression of USP21 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
USP21ENSG00000143258.11728.84840454.440000.6814010.421409.30100HepG2CKAP4
USP21ENSG00000143258.11415.51990578.85870-0.478303.869603.13230HepG2CELF1
USP21ENSG00000143258.11599.26610420.387200.511405.884304.72990HepG2DDX19B
USP21ENSG00000143258.11312.23180439.53950-0.493402.438401.85490HepG2DDX6
USP21ENSG00000143258.11659.85790813.56190-0.302102.653602.06220HepG2ETF1
USP21ENSG00000143258.11489.35050361.603300.436402.675901.90370HepG2FUBP3
USP21ENSG00000143258.11675.97390471.127900.520703.546702.76980HepG2FXR1
USP21ENSG00000143258.11582.33770436.976600.414202.218301.61960HepG2G3BP1
USP21ENSG00000143258.11640.87700442.626900.533903.762502.95790HepG2HNRNPK
USP21ENSG00000143258.11538.89340394.763800.448903.679703.00090HepG2PCBP1
USP21ENSG00000143258.11605.00650476.440600.344602.619001.86390HepG2PRPF4
USP21ENSG00000143258.11608.82020435.050400.484703.810503.09390HepG2QKI
USP21ENSG00000143258.11227.67190383.61570-0.752703.190102.43680HepG2RAVER1
USP21ENSG00000143258.11622.41110447.035300.477404.029703.39910HepG2NELFE
USP21ENSG00000143258.11553.00660416.333000.409503.035202.39340HepG2RECQL
USP21ENSG00000143258.11446.36680348.463100.357102.404401.79740HepG2SAFB2
USP21ENSG00000143258.11759.62510418.217700.8609013.0765011.94020HepG2SF3B4
USP21ENSG00000143258.11187.37590276.62700-0.562002.422801.48240HepG2TFIP11
USP21ENSG00000143258.11339.36880470.78400-0.472203.869303.06380HepG2UPF1
USP21ENSG00000143258.111225.16290935.952200.388404.684403.98020K562AGGF1
USP21ENSG00000143258.111350.51520973.891200.471603.927803.14830K562AKAP8L
USP21ENSG00000143258.11778.52290548.920700.504003.582802.53520K562EFTUD2
USP21ENSG00000143258.11728.61150572.669600.347302.684301.41560K562EWSR1
USP21ENSG00000143258.11448.39530599.61270-0.419302.410501.37060K562FKBP4
USP21ENSG00000143258.11297.94300475.65250-0.674904.034103.14100K562G3BP2
USP21ENSG00000143258.111381.708701033.575200.418703.951002.94290K562KIF1C
USP21ENSG00000143258.11835.50930589.842400.502203.386502.30570K562PCBP2
USP21ENSG00000143258.111357.570901627.72970-0.261802.517401.60050K562PUM2
USP21ENSG00000143258.111606.44230965.900700.733809.469908.51460K562PUS1
USP21ENSG00000143258.111450.62580941.068400.6242010.039708.93600K562RBM15
USP21ENSG00000143258.111085.42650916.524000.243902.049601.34030K562SF3A3
USP21ENSG00000143258.11723.78010494.564800.549305.686404.43210K562SF3B4
USP21ENSG00000143258.111348.63700830.314100.699703.027701.72040K562SNRNP200
USP21ENSG00000143258.11843.39980639.078800.400102.764702.05750K562TARDBP
USP21ENSG00000143258.11743.09860975.00470-0.391902.685901.50370K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for USP21 is not available on ENCORE database.





22 RBPs can affect the splicing of USP21 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.442000.000010.00092excludedK562PRPF8
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.352000.000130.05655excludedK562XRN2
SEUSP21ENSG00000143258.11chr1+161133344161133409161132708161132864161133667161133712-0.077000.000010.00015excludedK562AQR
SEUSP21ENSG00000143258.11chr1+161132404161132516161132059161132180161132708161132864-0.081000.000330.00668excludedK562PUS1
SEUSP21ENSG00000143258.11chr1+161132404161132516161132059161132180161132708161132864-0.249000.000920.05666excludedHepG2FTO
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.273000.000020.00493excludedHepG2LARP4
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.260000.000040.00236excludedHepG2SF3A3
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.421000.000930.06411excludedHepG2TIAL1
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.180000.000240.04546excludedK562EIF4G2
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.365000.000490.02457excludedHepG2HNRNPU
SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.337000.000820.03455excludedK562PTBP1
SEUSP21ENSG00000143258.11chr1+161132404161132516161132059161132180161132708161132864-0.167000.000150.00381excludedK562HNRNPC
A5SSUSP21ENSG00000143258.11chr1+161133667161133771161133667161133712161133953161134040-0.089000.000620.09933shorterK562HNRNPUL1
A5SSUSP21ENSG00000143258.11chr1+161133667161133771161133667161133712161133953161134040-0.181000.000160.02587shorterK562SUPV3L1
A5SSUSP21ENSG00000143258.11chr1+1611348601611350251611348601611349331611351461611355130.141000.000260.02689longerHepG2SF3B4
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.223000.000010.00006includedK562PUS1
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.162000.000910.06720includedK562HNRNPU
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.248000.000000.00007includedK562AGGF1
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.314000.000000.00000includedK562AKAP8L
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.229000.000480.00652includedHepG2TAF15
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.276000.000000.00001includedK562RBM15
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.468000.000000.00000includedHepG2SF3B4
RIUSP21ENSG00000143258.11chr1+161134323161134732161134323161134402161134624161134732-0.274000.000000.00010excludedHepG2RBM22
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.295000.000090.00179includedHepG2HNRNPK
RIUSP21ENSG00000143258.11chr1+1611343231611347321611343231611344021611346241611347320.194000.001080.00723includedK562AQR
MXEUSP21ENSG00000143258.11chr1+161133953161134040161134323161134732161133668161133771161134818161134933-0.191000.012110.099612includedK562DROSHA
MXEUSP21ENSG00000143258.11chr1+161133344161133409161133667161133712161132708161132864161133953161134040-0.087000.000760.007212includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for USP21 is not avaliable on ENCORE database.