HPS1

General Information

Gene Name       : HPS1
Gene ID             : ENSG00000107521.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HPS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HPS1ENSG00000107521.1823.0131.1527.08ENCSR000AEF
HepG2HPS1ENSG00000107521.1823.3914.5318.96ENCSR985KAT
K562HPS1ENSG00000107521.1825.4520.8423.14ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HPS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HPS1 RNA is bound by 18 proteins.  







eCLIP assay for HPS1 is not avaliable on ENCORE database.





18 proteins are bound to HPS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10100176967100177049-3'-UTR,intron-Distal4.566456.54425K562LIN28B
chr10100206596100206675-5'-UTR,intron-Distal,intron-Proximal5.153697.13477K562DDX3X
chr10100206562100206596-5'-UTR,intron-Distal4.339677.22925K562DDX3X
chr10100205153100205170-5'-UTR,intron-Distal,intron-Proximal3.511055.06399K562DDX3X
chr10100206581100206639-5'-UTR,intron-Distal,intron-Proximal5.512169.60748HepG2DDX3X
chr10100205099100205153-5'-UTR,intron-Distal4.129726.42503K562DDX3X
chr10100206498100206578-5'-UTR,intron-Distal4.708594.13847K562AQR
chr10100206530100206675-5'-UTR,intron-Distal,intron-Proximal3.763705.82539HepG2NCBP2
chr10100190931100190976-CDS,intron-Distal3.394527.18470K562YBX3
chr10100193812100193876-CDS,intron-Distal,intron-Proximal3.742647.38843HepG2BUD13
chr10100202940100202994-CDS,intron-Distal3.938373.30425K562LIN28B
chr10100193778100193836-CDS,intron-Distal4.088998.99212K562YBX3
chr10100195028100195055-CDS,intron-Distal,intron-Proximal3.650066.36816K562YBX3
chr10100190887100190891-CDS,intron-Distal,intron-Proximal3.099084.61374K562YBX3
chr10100185269100185336-CDS,intron-Distal,intron-Proximal3.891227.47181HepG2PRPF8
chr10100189613100189671-CDS,intron-Distal,intron-Proximal4.181375.47926K562AQR
chr10100186927100187016-CDS,intron-Distal,intron-Proximal4.703046.13877K562SRSF1
chr10100183366100183503-CDS,intron-Distal,intron-Proximal3.9726213.83580HepG2PRPF8
chr10100190997100191047-CDS,intron-Distal,intron-Proximal3.732413.86355HepG2PPIG
chr10100190332100190428-CDS,intron-Distal,intron-Proximal3.738057.00784K562METAP2
chr10100193677100193755-CDS,intron-Distal,intron-Proximal3.183716.18341HepG2PRPF8
chr10100190887100190901-CDS,intron-Distal,intron-Proximal3.744753.84718K562METAP2
chr10100190402100190428-CDS,intron-Distal,intron-Proximal4.2742112.43828K562YBX3
chr10100186993100187074-CDS,intron-Distal,intron-Proximal3.830988.55183K562SF3B4
chr10100193825100193883-CDS,intron-Distal,intron-Proximal4.264275.97994K562AQR
chr10100183383100183480-CDS,intron-Distal,intron-Proximal5.939618.41916K562EFTUD2
chr10100189395100189475-CDS,intron-Distal,intron-Proximal5.0097011.52732K562SF3B4
chr10100186961100187025-CDS,intron-Distal,intron-Proximal3.4247810.05760HepG2PRPF8
chr10100185583100185710-CDS,intron-Distal,intron-Proximal3.538894.93175HepG2GRWD1
chr10100189628100189733-CDS,intron-Distal,intron-Proximal6.200668.50915HepG2EFTUD2
chr10100190267100190373-CDS,intron-Distal,intron-Proximal3.9000011.67840HepG2PRPF8
chr10100185670100185779-CDS,intron-Distal,intron-Proximal4.201323.94554K562XRN2
chr10100193836100193849-CDS,intron-Distal,intron-Proximal3.120625.51805K562YBX3
chr10100190922100191007-CDS,intron-Distal3.690876.08728K562METAP2
chr10100202879100202933-CDS,intron-Distal,intron-Proximal3.011423.95327HepG2PPIG
chr10100190375100190402-CDS,intron-Distal4.8690513.47990K562YBX3
chr10100183392100183492-CDS,intron-Distal,intron-Proximal5.541955.99517HepG2EFTUD2
chr10100185721100185790-CDS,intron-Distal,intron-Proximal4.5078911.33835K562SF3B4
chr10100193830100193917-CDS,intron-Distal,intron-Proximal5.133728.23509HepG2AQR
chr10100202935100202996-CDS,intron-Distal3.522774.14015K562DDX24
chr10100189616100189710-CDS,intron-Distal,intron-Proximal5.569208.26501K562SF3B4
chr10100189649100189741-intron-Distal,intron-Proximal4.252243.90256HepG2PRPF4
chr10100190282100190309-intron-Distal,intron-Proximal4.9211010.24966K562AQR
chr10100190193100190257-intron-Distal,intron-Proximal3.767204.93376K562PRPF8
chr10100195319100195364-intron-Distal,intron-Proximal4.525003.90539HepG2RBM22
chr10100186467100186552-intron-Distal3.105686.48483K562HNRNPL
chr10100189402100189451-intron-Distal,intron-Proximal4.989507.19196HepG2SF3B4
chr10100183714100183818-intron-Distal,intron-Proximal4.675356.67793HepG2EFTUD2
chr10100190219100190268-intron-Distal,intron-Proximal4.162634.89208K562AQR
chr10100190309100190328-intron-Distal,intron-Proximal3.484566.87160K562AQR
chr10100190247100190293-intron-Distal,intron-Proximal3.047453.01994K562BUD13
chr10100183724100183779-intron-Distal,intron-Proximal3.308213.59805HepG2SF3B4
chr10100185232100185269-intron-Distal,intron-Proximal4.372963.64476HepG2PRPF8
chr10100183644100183724-intron-Distal,intron-Proximal4.824427.30082HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HPS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HPS1 is not available on ENCORE database.

  • 103 RBPs can affect the levels of HPS1.  








The Knockdown/knockout RNA-Seq assay for HPS1 is not available on ENCORE database.





103 RBPs can affect the gene expression of HPS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HPS1ENSG00000107521.14237.14590359.78630-0.601402.285501.30910HepG2AATF
HPS1ENSG00000107521.14539.24930284.675600.921504.132103.41710HepG2BOP1
HPS1ENSG00000107521.14253.17070364.43600-0.525602.538501.79810HepG2CALR
HPS1ENSG00000107521.14822.71130557.854000.560404.370903.41100HepG2CIRBP
HPS1ENSG00000107521.14535.30240396.326100.433602.807502.12570HepG2DDX21
HPS1ENSG00000107521.14257.15950388.35560-0.594702.276501.45730HepG2DDX24
HPS1ENSG00000107521.14511.21610306.808400.736509.440608.32180HepG2DNAJC2
HPS1ENSG00000107521.14786.89940561.328400.487203.341402.69420HepG2EIF2S1
HPS1ENSG00000107521.14959.65190620.263300.629504.941204.08990HepG2EIF4A3
HPS1ENSG00000107521.14671.75560498.423800.430503.213202.31430HepG2EWSR1
HPS1ENSG00000107521.14446.96210256.270700.802406.161304.82630HepG2GEMIN5
HPS1ENSG00000107521.14461.84260290.253900.670003.590902.31910HepG2GRSF1
HPS1ENSG00000107521.14499.56430312.498700.676705.312804.45830HepG2HNRNPA1
HPS1ENSG00000107521.14440.62890258.968200.766704.993803.08880HepG2HNRNPAB
HPS1ENSG00000107521.14662.98010347.599800.9314010.218608.95970HepG2HNRNPC
HPS1ENSG00000107521.14594.28540469.364700.340302.489701.80780HepG2HNRNPF
HPS1ENSG00000107521.14421.25020588.19830-0.481603.087702.35140HepG2HNRNPK
HPS1ENSG00000107521.14660.53300504.383100.389004.046503.24380HepG2HNRNPL
HPS1ENSG00000107521.14734.75580462.188600.668707.429106.29530HepG2IGF2BP1
HPS1ENSG00000107521.14507.89440352.713600.525905.511704.50670HepG2ILF2
HPS1ENSG00000107521.14982.74140510.274300.945409.300407.77000HepG2LARP4
HPS1ENSG00000107521.14766.22500549.086800.480604.981303.96180HepG2NOL12
HPS1ENSG00000107521.14435.06280307.980900.498303.778702.92970HepG2PPIL4
HPS1ENSG00000107521.14465.62620593.99470-0.351302.640602.10410HepG2PTBP1
HPS1ENSG00000107521.14796.35910556.464400.517007.741806.85350HepG2PUM1
HPS1ENSG00000107521.14692.52830519.540700.414504.173803.44420HepG2PUS1
HPS1ENSG00000107521.14521.73210643.33170-0.302301.937601.40010HepG2QKI
HPS1ENSG00000107521.14358.14240583.85700-0.705106.755305.74270HepG2RBM25
HPS1ENSG00000107521.14299.62590418.80560-0.483102.885501.87180HepG2RBM27
HPS1ENSG00000107521.14451.30130280.141100.687805.177704.36700HepG2RPS19
HPS1ENSG00000107521.14476.22950314.913000.596603.182502.32570HepG2RPS3A
HPS1ENSG00000107521.14366.42470574.45710-0.648703.993603.17700HepG2SF3A3
HPS1ENSG00000107521.14462.55120618.44260-0.419003.460802.80910HepG2SF3B4
HPS1ENSG00000107521.14630.99290502.661600.327902.974302.24940HepG2SLBP
HPS1ENSG00000107521.14599.36460376.055100.672403.041402.03360HepG2SMNDC1
HPS1ENSG00000107521.14855.67910724.504600.240001.991201.54500HepG2SRFBP1
HPS1ENSG00000107521.14423.41300301.102000.491702.194901.31510HepG2SRSF3
HPS1ENSG00000107521.14630.13240517.581600.283802.228501.65970HepG2SRSF5
HPS1ENSG00000107521.14736.60600461.141000.675609.073207.94000HepG2SRSF7
HPS1ENSG00000107521.14650.66090413.438800.654105.889604.54260HepG2SUPT6H
HPS1ENSG00000107521.14378.51330580.19250-0.616206.127805.34850HepG2TAF15
HPS1ENSG00000107521.14405.29710533.13890-0.395502.750701.91670HepG2TIA1
HPS1ENSG00000107521.14536.06920335.514300.675906.470905.76600HepG2TIAL1
HPS1ENSG00000107521.14699.63490338.525001.0472019.7185018.38700HepG2TRIM56
HPS1ENSG00000107521.14707.05670512.144300.465203.201602.25480HepG2TUFM
HPS1ENSG00000107521.14351.89500225.001900.645103.022702.23160HepG2UCHL5
HPS1ENSG00000107521.14710.80800560.303900.343203.343902.75910HepG2ZNF622
HPS1ENSG00000107521.14385.12760589.21520-0.613503.553302.19800K562AARS
HPS1ENSG00000107521.14972.21200549.216300.823803.770001.75240K562ADAR
HPS1ENSG00000107521.14854.445301089.13100-0.350103.428002.80870K562AGGF1
HPS1ENSG00000107521.141425.568301013.539500.492004.649603.92400K562AQR
HPS1ENSG00000107521.14896.93980456.598600.9740011.9911010.13550K562BOP1
HPS1ENSG00000107521.14876.85780537.843100.705105.884904.19730K562CCAR1
HPS1ENSG00000107521.14960.46780571.181400.749708.963706.82120K562CIRBP
HPS1ENSG00000107521.141586.04530948.975500.740907.744705.22210K562CKAP4
HPS1ENSG00000107521.141843.55130824.743101.1604011.079708.96270K562CNOT7
HPS1ENSG00000107521.141074.67190871.828600.301702.602301.52970K562CPEB4
HPS1ENSG00000107521.14999.50240485.440401.0418017.8510015.83620K562CPSF6
HPS1ENSG00000107521.14805.86690536.932600.585705.529303.95550K562CSTF2
HPS1ENSG00000107521.142837.733901784.973500.6687012.9767010.95530K562CELF1
HPS1ENSG00000107521.141705.117001123.373500.6019010.998208.60600K562DDX21
HPS1ENSG00000107521.141069.18300902.178200.244902.086501.50790K562DDX47
HPS1ENSG00000107521.14898.41810602.163900.577105.176003.24720K562DHX30
HPS1ENSG00000107521.14849.834501219.51910-0.521107.316905.77850K562DKC1
HPS1ENSG00000107521.141047.59310698.679200.584303.571202.09740K562EEF2
HPS1ENSG00000107521.14876.11470698.117500.327502.930101.67820K562EIF2S1
HPS1ENSG00000107521.141938.765801451.623300.417405.938504.58100K562EIF4G2
HPS1ENSG00000107521.141465.57590647.904801.1775014.2348012.15040K562FIP1L1
HPS1ENSG00000107521.14803.30960494.030400.701306.830505.46320K562FMR1
HPS1ENSG00000107521.14771.87100418.781500.882104.970503.70490K562FTO
HPS1ENSG00000107521.14140.01060330.17900-1.237706.787505.57070K562G3BP2
HPS1ENSG00000107521.141223.16510727.941000.7486013.3710011.12140K562GLRX3
HPS1ENSG00000107521.14876.55990463.432200.9194012.1411010.46200K562GPKOW
HPS1ENSG00000107521.141753.641901298.533400.433404.441603.48810K562GRSF1
HPS1ENSG00000107521.141257.08660644.235900.9643016.3926015.02070K562HNRNPC
HPS1ENSG00000107521.14825.26000575.516600.519903.470802.18250K562HNRNPF
HPS1ENSG00000107521.14376.89470532.24240-0.497902.985201.70110K562HNRNPK
HPS1ENSG00000107521.14761.50040533.063000.514403.229002.08990K562IGF2BP2
HPS1ENSG00000107521.141142.76570752.743900.602202.862801.41890K562ILF2
HPS1ENSG00000107521.14770.82480561.966800.455803.248701.62180K562ILF3
HPS1ENSG00000107521.14710.35730395.828500.843603.070102.08000K562KRR1
HPS1ENSG00000107521.14710.57530558.943200.346202.457001.59210K562MATR3
HPS1ENSG00000107521.141005.659401347.34000-0.422004.525403.30310K562MBNL1
HPS1ENSG00000107521.14833.22950452.380100.8811011.307909.45730K562METAP2
HPS1ENSG00000107521.142263.104501547.270700.548506.320004.62760K562MSI2
HPS1ENSG00000107521.141259.10160765.329000.7181014.8628013.16830K562MTPAP
HPS1ENSG00000107521.141583.63630850.383200.8970030.5654028.53030K562NSUN2
HPS1ENSG00000107521.141231.15620792.336300.635703.735002.27700K562PABPC1
HPS1ENSG00000107521.141787.722201313.314200.444803.339202.42560K562PCBP3
HPS1ENSG00000107521.141265.85420735.659400.782905.403704.19620K562PPIG
HPS1ENSG00000107521.14370.35300656.77960-0.826505.607704.53830K562PRPF8
HPS1ENSG00000107521.141975.007201650.609300.258802.628901.69170K562PUM2
HPS1ENSG00000107521.14735.44820527.347700.479802.487901.55220K562RCC2
HPS1ENSG00000107521.14760.63110549.058100.470103.435202.19830K562NELFE
HPS1ENSG00000107521.14774.60090580.832300.415202.473801.53320K562RPS3
HPS1ENSG00000107521.141133.93250751.235000.593903.409401.68150K562SBDS
HPS1ENSG00000107521.141106.42410839.060600.399004.365503.35920K562SF3A3
HPS1ENSG00000107521.14850.90470592.291900.522603.909702.38590K562SLBP
HPS1ENSG00000107521.14707.93170499.882000.501903.309702.16190K562SRFBP1
HPS1ENSG00000107521.141158.31210859.631200.430105.137703.90840K562SRPK2
HPS1ENSG00000107521.14842.69010533.493300.659407.474206.32110K562SRSF1
HPS1ENSG00000107521.14792.85050560.615300.499902.992301.88680K562SRSF4
HPS1ENSG00000107521.14652.59790503.880100.373002.357401.40050K562SRSF5
HPS1ENSG00000107521.141456.375901002.488900.538708.791806.70770K562SRSF7
HPS1ENSG00000107521.141039.93150635.592300.710205.224303.78900K562SUPV3L1
HPS1ENSG00000107521.14622.403401010.41680-0.699009.723408.17580K562SYNCRIP
HPS1ENSG00000107521.141015.70610539.898800.911604.972004.00980K562TARDBP
HPS1ENSG00000107521.14741.74450520.801500.510104.661003.55720K562TIA1
HPS1ENSG00000107521.14950.72880555.601000.774907.892506.24550K562TIAL1
HPS1ENSG00000107521.141027.97640590.573000.799502.761601.81740K562TRIM56
HPS1ENSG00000107521.141848.815901421.472800.379105.612803.77690K562TROVE2
HPS1ENSG00000107521.14217.51520319.71960-0.555702.347001.35000K562U2AF1
HPS1ENSG00000107521.14199.73530330.30910-0.725703.507602.60410K562U2AF2
HPS1ENSG00000107521.141085.31320672.852400.689606.839705.15660K562UCHL5
HPS1ENSG00000107521.141403.55580901.676600.6383012.6837011.28380K562UPF1
HPS1ENSG00000107521.141055.09460756.246000.480303.757602.34730K562UTP3
HPS1ENSG00000107521.141286.23800771.540600.7372010.117808.40570K562WDR3
HPS1ENSG00000107521.14978.82770802.282500.286802.850301.99120K562WDR43
HPS1ENSG00000107521.141694.806101200.870700.496905.905604.01930K562WRN
HPS1ENSG00000107521.14933.82820685.398400.446103.028601.74440K562XRN2
HPS1ENSG00000107521.142274.484001141.779500.9942020.8130018.29260K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HPS1 is not available on ENCORE database.





22 RBPs can affect the splicing of HPS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.395000.000000.00001includedK562XRN2
SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.341000.000000.00415includedK562GEMIN5
SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.288000.000490.04564includedK562XRCC6
SEHPS1ENSG00000107521.14chr10-100195028100195171100193739100193848100195391100195529-0.290000.000000.00012excludedHepG2HNRNPK
SEHPS1ENSG00000107521.14chr10-100190887100191048100190327100190427100193696100193848-0.371000.000500.01530excludedHepG2HNRNPK
SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.302000.000000.01627includedK562NONO
SEHPS1ENSG00000107521.14chr10-100195028100195171100193739100193848100195391100195529-0.230000.000040.00630excludedHepG2DDX3X
SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.401000.000000.00000includedK562SUPV3L1
SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.384000.000000.00008includedK562UCHL5
SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.308000.000000.00059includedK562EFTUD2
SEHPS1ENSG00000107521.14chr10-100195028100195171100193739100193848100195391100195529-0.225000.000150.00950excludedHepG2MATR3
SEHPS1ENSG00000107521.14chr10-100195028100195171100193739100193848100195391100195529-0.147000.001130.07172excludedHepG2IGF2BP3
SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.403000.000230.02874includedHepG2SUPV3L1
SEHPS1ENSG00000107521.14chr10-100189547100189646100188907100189399100190327100190427-0.294000.000890.04366excludedHepG2PCBP1
SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.384000.000320.09014includedHepG2BCCIP
SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.241000.000060.01478includedK562SRSF7
SEHPS1ENSG00000107521.14chr10-100190887100191048100190327100190427100193696100193848-0.128000.003010.07679excludedK562UTP18
SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.421000.000130.03461includedHepG2DDX55
SEHPS1ENSG00000107521.14chr10-100195028100195171100193739100193848100195391100195529-0.236000.000160.01110excludedK562HNRNPK
SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.448000.001810.06723includedHepG2HNRNPU
SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.474000.000300.01511includedHepG2HNRNPC
SEHPS1ENSG00000107521.14chr10-100195028100195171100193739100193848100195391100195529-0.203000.000330.01690excludedK562PTBP1
SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.290000.000000.00000includedK562HNRNPC
SEHPS1ENSG00000107521.14chr10-100189547100189646100188907100189399100190327100190427-0.316000.000000.00002excludedK562HNRNPC
A3SSHPS1ENSG00000107521.14chr10-1001903271001905371001903271001904271001908871001910480.161000.000000.00001longerHepG2U2AF1
A3SSHPS1ENSG00000107521.14chr10-1001903271001905371001903271001904271001908871001910480.142000.000730.05449longerHepG2SF3B4
A5SSHPS1ENSG00000107521.14chr10-100193696100193848100193739100193848100190887100191048-0.163000.000070.06705shorterK562DHX30

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HPS1 is not avaliable on ENCORE database.