DLD

General Information

Gene Name       : DLD
Gene ID             : ENSG00000091140.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DLD)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DLDENSG00000091140.13233.25213.58223.42ENCSR000AEF
HepG2DLDENSG00000091140.1348.66102.5175.59ENCSR985KAT
K562DLDENSG00000091140.13399.57429.46414.51ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DLD is not avaliable on ENCORE database.



Proteins bound to RNA
  • DLD RNA is bound by 29 proteins.  







eCLIP assay for DLD is not avaliable on ENCORE database.





29 proteins are bound to DLD RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7107560031107560118+3'-UTR,intron-Distal3.990517.12816K562NOLC1
chr7107559893107560028+3'-UTR,intron-Distal,intron-Proximal5.2411429.90318K562IGF2BP1
chr7107559647107559706+3'-UTR,CDS3.891895.36555HepG2BCLAF1
chr7107560041107560111+3'-UTR,intron-Distal7.4570830.55090HepG2SUB1
chr7107560325107560455+3'-UTR,intron-Distal3.040238.57868K562KHSRP
chr7107559454107559533+3'-UTR,CDS,intron-Proximal3.369216.42235K562LIN28B
chr7107557902107557962+3'-UTR,CDS,intron-Proximal3.284595.28960K562AQR
chr7107545893107545948+3'-UTR,CDS,intron-Distal4.0645313.41447K562YBX3
chr7107559615107559662+3'-UTR,CDS,intron-Proximal4.6385612.14994K562SF3B4
chr7107560237107560288+3'-UTR,intron-Distal4.215099.20314HepG2SUB1
chr7107557857107557902+3'-UTR,CDS3.465993.79230K562SND1
chr7107545079107545117+3'-UTR,CDS,intron-Distal,intron-Proximal3.212748.32476K562KHSRP
chr7107545805107545893+3'-UTR,CDS,intron-Distal,intron-Proximal3.3791112.56103K562YBX3
chr7107560111107560149+3'-UTR,intron-Distal5.2599611.22320HepG2SUB1
chr7107560217107560301+3'-UTR,intron-Distal3.024016.27356K562NOLC1
chr7107545292107545359+3'-UTR,CDS,intron-Distal,intron-Proximal3.352056.67026K562KHSRP
chr7107560176107560216+3'-UTR,intron-Distal3.240593.78871K562IGF2BP1
chr7107560223107560299+3'-UTR,intron-Distal4.3920110.55775K562IGF2BP1
chr7107559497107559544+3'-UTR,CDS4.611845.23259HepG2BCLAF1
chr7107545399107545504+3'-UTR,5'-UTR,CDS,intron-Proximal4.471028.41475HepG2BCLAF1
chr7107560140107560219+3'-UTR,intron-Distal4.3418217.46896K562PUM2
chr7107545897107545946+3'-UTR,CDS,intron-Distal3.134204.22960K562SND1
chr7107545398107545487+3'-UTR,5'-UTR,CDS,intron-Proximal3.337305.49645K562GRWD1
chr7107558446107558508+3'-UTR,CDS,intron-Proximal4.126903.36483HepG2G3BP1
chr7107546732107546768+3'-UTR,CDS3.961536.36657K562YBX3
chr7107557302107557356+3'-UTR,CDS6.183479.64515K562RPS3
chr7107555990107556073+3'-UTR,CDS3.034703.59323K562LIN28B
chr7107560123107560176+3'-UTR,intron-Distal3.514744.63751K562IGF2BP1
chr7107558456107558508+3'-UTR,CDS,intron-Proximal3.897005.20093K562DDX24
chr7107531729107531833+5'-UTR,CDS,intron-Proximal4.035333.31384K562XRN2
chr7107543922107543946+5'-UTR,CDS,intron-Proximal3.879145.85226K562UCHL5
chr7107531725107531734+5'-UTR,CDS3.111726.83987K562YBX3
chr7107533680107533724+5'-UTR,CDS,intron-Proximal3.2749712.39963K562YBX3
chr7107533643107533714+5'-UTR,CDS,intron-Proximal3.784486.80054K562GRWD1
chr7107531682107531735+5'-UTR,CDS,intron-Proximal3.5420218.38357K562UCHL5
chr7107533652107533660+5'-UTR,CDS3.3751910.48258K562YBX3
chr7107531728107531735+5'-UTR,CDS,intron-Proximal3.409095.22707K562GRWD1
chr7107531611107531675+5'-UTR3.127138.99559K562GRWD1
chr7107531732107531746+5'-UTR,CDS,intron-Proximal4.077075.63763K562AQR
chr7107531675107531728+5'-UTR,CDS4.2420315.14134K562GRWD1
chr7107531644107531735+5'-UTR,CDS,intron-Proximal3.867454.00952K562ZNF800
chr7107531622107531682+5'-UTR3.0104911.82716K562UCHL5
chr7107531605107531678+5'-UTR3.4787321.75530K562DDX3X
chr7107533644107533721+5'-UTR,CDS,intron-Proximal3.082105.12345HepG2GRWD1
chr7107531678107531735+5'-UTR,CDS,intron-Proximal3.1005825.20770K562DDX3X
chr7107543924107543972+5'-UTR,CDS4.123514.60638K562GRWD1
chr7107531722107531775+5'-UTR,CDS,intron-Proximal3.403754.57930K562GPKOW
chr7107533660107533680+5'-UTR,CDS4.0106815.29541K562YBX3
chr7107542831107542908+CDS,intron-Distal,intron-Proximal4.014695.85201K562PRPF8
chr7107545525107545613+intron-Distal,intron-Proximal3.347535.42680K562KHSRP
chr7107548128107548197+intron-Distal4.562505.58061HepG2SUGP2
chr7107554394107554462+intron-Distal3.638544.31658K562EXOSC5
chr7107553970107553994+intron-Distal3.490813.72952K562EXOSC5
chr7107554753107554800+intron-Distal4.638545.12432K562EXOSC5
chr7107546020107546092+intron-Distal,intron-Proximal3.042183.13218K562PRPF8
chr7107548280107548369+intron-Distal4.586005.26569K562MATR3
chr7107553267107553344+intron-Distal3.427055.57520K562EXOSC5
chr7107558154107558247+intron-Distal3.945906.19377K562KHSRP
chr7107547993107548040+intron-Distal3.922023.63454HepG2SUGP2
chr7107542869107542922+intron-Distal,intron-Proximal4.504014.03304K562RBM22
chr7107544999107545022+intron-Distal,intron-Proximal3.506314.30679K562KHSRP
chr7107534367107534412+intron-Distal3.017773.07751K562KHSRP
chr7107545197107545264+intron-Distal,intron-Proximal3.7269515.32384K562KHSRP
chr7107548282107548362+intron-Distal4.593726.10726HepG2SUGP2
chr7107549375107549420+intron-Distal3.685053.04224HepG2SUGP2
chr7107564383107564519+intron-Distal3.843293.06015K562MATR3
chr7107545050107545079+intron-Distal,intron-Proximal3.505278.26817K562KHSRP
chr7107547850107547903+intron-Distal4.789865.43236K562PTBP1
chr7107533771107533839+intron-Distal,intron-Proximal3.469087.20875K562KHSRP
chr7107546018107546063+intron-Distal,intron-Proximal4.623976.07567K562KHSRP
chr7107547672107547723+intron-Distal3.953773.79098HepG2SUGP2
chr7107544965107544999+intron-Distal5.202919.82431K562KHSRP
chr7107547472107547608+intron-Distal4.0487211.57186K562MATR3
chr7107547303107547388+intron-Distal4.353994.86548HepG2SUGP2
chr7107535930107536032+intron-Distal4.973189.32497K562HNRNPL
chr7107535926107536032+intron-Distal4.285194.21977HepG2HNRNPL
chr7107559577107559614+intron-Proximal4.983348.80869K562EFTUD2
chr7107544021107544067+intron-Proximal4.830105.94830K562TIA1
chr7107559587107559615+intron-Proximal5.154166.90654K562SF3B4
chr7107531746107531775+intron-Proximal3.775636.32052K562AQR
chr7107533781107533823+intron-Proximal4.073683.31283K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DLD is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DLD is not available on ENCORE database.

  • 90 RBPs can affect the levels of DLD.  








The Knockdown/knockout RNA-Seq assay for DLD is not available on ENCORE database.





90 RBPs can affect the gene expression of DLD :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DLDENSG00000091140.81077.047701344.22270-0.319702.203101.31200HepG2ADAR
DLDENSG00000091140.83670.582802221.169300.724608.324607.45630HepG2AKAP1
DLDENSG00000091140.81423.288101837.83980-0.368802.739201.95840HepG2ASCC1
DLDENSG00000091140.83110.524602544.311700.289804.190003.37820HepG2AUH
DLDENSG00000091140.82505.727701842.510500.443505.108404.09980HepG2CALR
DLDENSG00000091140.81429.995602319.63370-0.697903.834402.67400HepG2CCAR1
DLDENSG00000091140.81819.880301578.315100.205402.459701.82510HepG2CKAP4
DLDENSG00000091140.81246.249001720.07120-0.464904.379103.53140HepG2CPSF6
DLDENSG00000091140.81667.703601380.432000.272602.763001.60490HepG2DDX1
DLDENSG00000091140.82727.022902127.730900.357902.717702.09630HepG2DDX3X
DLDENSG00000091140.81365.168701827.72070-0.421002.899902.26910HepG2DDX6
DLDENSG00000091140.81044.925701353.61550-0.373404.425003.55120HepG2DNAJC21
DLDENSG00000091140.81082.483801757.07610-0.698808.059107.08450HepG2EIF2S1
DLDENSG00000091140.8713.510401722.96570-1.271908.022106.29960HepG2FTO
DLDENSG00000091140.81224.35850997.782100.295102.182801.47710HepG2FUBP3
DLDENSG00000091140.8567.12320918.53570-0.695702.417401.37560HepG2GRSF1
DLDENSG00000091140.8988.028001366.58230-0.467904.752103.93590HepG2HNRNPA1
DLDENSG00000091140.81475.579301774.65380-0.266302.920502.18470HepG2HNRNPF
DLDENSG00000091140.81515.160701840.21530-0.280401.955801.36180HepG2HNRNPK
DLDENSG00000091140.81635.778302116.37850-0.371607.487006.42710HepG2HNRNPL
DLDENSG00000091140.81418.861701747.53420-0.300602.687001.97320HepG2IGF2BP1
DLDENSG00000091140.81411.031601959.81120-0.474004.141003.34140HepG2MAGOH
DLDENSG00000091140.81023.577001970.79040-0.9452012.5033011.23120HepG2MATR3
DLDENSG00000091140.81836.898501548.690200.246102.223901.49440HepG2MSI2
DLDENSG00000091140.81876.051702303.80630-0.296303.264502.43880HepG2NOL12
DLDENSG00000091140.81058.622701573.52100-0.571802.551601.50610HepG2NONO
DLDENSG00000091140.81075.367501346.79380-0.324703.444802.63100HepG2PPIL4
DLDENSG00000091140.81630.788601251.732000.381505.340204.30060HepG2PRPF4
DLDENSG00000091140.81615.075201322.294500.288502.001801.31070HepG2PRPF8
DLDENSG00000091140.81659.275502199.18030-0.406404.434603.70080HepG2PUF60
DLDENSG00000091140.82318.540601486.231100.641503.760702.94360HepG2RAVER1
DLDENSG00000091140.82363.068501803.119800.390102.161001.55980HepG2RBM25
DLDENSG00000091140.81072.088501344.73150-0.326904.311203.53880HepG2SAFB2
DLDENSG00000091140.82417.799801909.925200.340105.239904.47040HepG2SF3B4
DLDENSG00000091140.81858.510302108.66050-0.182202.147201.51530HepG2SLBP
DLDENSG00000091140.81976.490302757.69780-0.4805011.6382010.80080HepG2SRFBP1
DLDENSG00000091140.83692.332701993.532500.8891037.8578036.55370HepG2SRSF1
DLDENSG00000091140.81906.190202171.36410-0.187901.951001.41400HepG2SRSF5
DLDENSG00000091140.82819.537802394.315000.235703.202502.66020HepG2SSB
DLDENSG00000091140.81224.849201706.14160-0.478103.334402.59950HepG2SUPV3L1
DLDENSG00000091140.81030.838501467.37160-0.509406.929306.20350HepG2TIAL1
DLDENSG00000091140.81128.237301480.34130-0.391905.948805.17790HepG2TRIM56
DLDENSG00000091140.8789.183101007.91480-0.352902.097801.43770HepG2UCHL5
DLDENSG00000091140.81187.403201719.10800-0.5339011.006909.78320HepG2UPF1
DLDENSG00000091140.8952.982301659.73520-0.8004020.9427019.52710HepG2UTP3
DLDENSG00000091140.81117.528001679.50730-0.587705.506504.49490HepG2XRN2
DLDENSG00000091140.81486.064801235.313600.266503.283702.56290HepG2ZC3H8
DLDENSG00000091140.82721.149401890.693400.5252016.2635015.21290HepG2ZNF622
DLDENSG00000091140.87164.971808770.83640-0.291802.692801.49130K562ABCF1
DLDENSG00000091140.84206.158909052.98690-1.1059030.3482028.60290K562AQR
DLDENSG00000091140.84402.087505084.40950-0.207903.088902.07780K562BCLAF1
DLDENSG00000091140.84841.820706109.03700-0.335402.699101.30370K562BUD13
DLDENSG00000091140.81307.690502278.44100-0.801007.290805.36790K562CCAR1
DLDENSG00000091140.85330.092806796.81740-0.350703.637002.15580K562CIRBP
DLDENSG00000091140.85301.194307946.82610-0.584102.817701.74220K562CNOT7
DLDENSG00000091140.86610.493707850.06700-0.247903.483302.23730K562CPEB4
DLDENSG00000091140.83409.309904893.92410-0.521505.158204.09400K562CPSF6
DLDENSG00000091140.83088.429103857.28200-0.320704.789503.34580K562CSTF2
DLDENSG00000091140.87196.110208143.75500-0.178502.132401.37500K562DKC1
DLDENSG00000091140.83451.638304325.57500-0.325602.690001.79030K562EFTUD2
DLDENSG00000091140.83778.382604572.37620-0.275204.223802.70450K562EIF2S1
DLDENSG00000091140.85436.214206398.82490-0.235202.025201.39260K562EIF2S2
DLDENSG00000091140.82495.506804348.93330-0.8013015.7887013.71110K562EIF4A3
DLDENSG00000091140.83277.409703916.49330-0.257002.907501.71750K562EIF4B
DLDENSG00000091140.83928.053704979.12320-0.342102.738401.88940K562FMR1
DLDENSG00000091140.82069.371404220.11340-1.0281017.5849015.10370K562FTO
DLDENSG00000091140.85218.959604522.715400.206502.616702.02480K562FXR1
DLDENSG00000091140.86739.823205091.570200.404502.758402.05260K562G3BP2
DLDENSG00000091140.84755.880205534.17950-0.218702.549501.45730K562GLRX3
DLDENSG00000091140.83209.511804672.62880-0.541905.563104.44100K562GPKOW
DLDENSG00000091140.83706.763808527.77990-1.2020017.9425015.95500K562GRSF1
DLDENSG00000091140.84839.582705705.03090-0.237402.306601.33220K562HNRNPA1
DLDENSG00000091140.82171.209804463.42680-1.0397027.1724025.38340K562HNRNPC
DLDENSG00000091140.83013.063303985.44420-0.403504.897503.32320K562HNRNPF
DLDENSG00000091140.86948.964605185.268600.422303.770202.67190K562HNRNPM
DLDENSG00000091140.85370.190706317.57770-0.234402.854801.94770K562HNRNPU
DLDENSG00000091140.84338.973706664.83010-0.6192011.230809.46090K562MAGOH
DLDENSG00000091140.84964.380806651.63070-0.422105.982904.55350K562MATR3
DLDENSG00000091140.83332.539504560.94990-0.452704.681203.52190K562METAP2
DLDENSG00000091140.84001.984705818.44660-0.5399018.3458016.52580K562MTPAP
DLDENSG00000091140.84908.722206464.93690-0.3973016.8314015.20200K562NSUN2
DLDENSG00000091140.83253.140304433.29940-0.446504.305703.26700K562PCBP3
DLDENSG00000091140.82564.010603400.54410-0.407405.526404.39580K562POLR2G
DLDENSG00000091140.82659.996404001.81800-0.589205.832604.44380K562PSIP1
DLDENSG00000091140.85172.758706475.14180-0.324003.883603.10950K562PTBP1
DLDENSG00000091140.87996.2487011730.57430-0.552908.752807.28750K562PUF60
DLDENSG00000091140.810046.6527012225.31040-0.283204.532403.29490K562PUM2
DLDENSG00000091140.85958.667607505.52300-0.333003.254002.67280K562PUS1
DLDENSG00000091140.84115.453706210.04300-0.593608.855307.21920K562RBM22
DLDENSG00000091140.82581.814103650.60210-0.499707.911106.23800K562RCC2
DLDENSG00000091140.84587.281305250.32910-0.194803.057701.38620K562RPS10
DLDENSG00000091140.85473.701906379.06410-0.220802.904702.07220K562SF3A3
DLDENSG00000091140.83514.263804443.34160-0.338402.487301.56700K562SF3B1
DLDENSG00000091140.84513.156605295.73590-0.230702.327501.54500K562SF3B4
DLDENSG00000091140.82030.934103460.72890-0.7689013.9625011.22660K562SRFBP1
DLDENSG00000091140.85251.071506347.56040-0.273602.936502.21140K562SRSF1
DLDENSG00000091140.82863.939803540.58970-0.306003.182502.03640K562SRSF4
DLDENSG00000091140.82465.485104076.17390-0.725309.253707.33110K562SUPV3L1
DLDENSG00000091140.84728.046503410.762100.471107.927206.52640K562SYNCRIP
DLDENSG00000091140.83184.751606424.65670-1.0124017.2974015.21900K562TARDBP
DLDENSG00000091140.85065.007906197.17250-0.291003.277902.37620K562TIA1
DLDENSG00000091140.82175.480103849.14490-0.8232012.7003010.58440K562TIAL1
DLDENSG00000091140.82682.067704088.61790-0.608309.473107.47670K562TRIM56
DLDENSG00000091140.83374.837404936.95880-0.548805.628603.95220K562U2AF1
DLDENSG00000091140.83456.449405098.28940-0.5607010.949409.34230K562U2AF2
DLDENSG00000091140.85091.973306854.90010-0.4289012.1758010.80190K562UPF1
DLDENSG00000091140.84051.873505865.53710-0.533709.171607.53880K562WDR3
DLDENSG00000091140.87954.5511010198.96800-0.358604.168003.07220K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DLD is not available on ENCORE database.





8 RBPs can affect the splicing of DLD :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDLDENSG00000091140.8chr7+107542769107542838107542182107542262107543922107543992-0.053000.000000.00000excludedK562SF3B4
SEDLDENSG00000091140.8chr7+107533644107533723107531618107531734107542182107542262-0.112000.000000.00000excludedK562SF3B4
SEDLDENSG00000091140.8chr7+107542769107542838107542182107542262107543922107543992-0.311000.000000.00000excludedHepG2U2AF1
SEDLDENSG00000091140.8chr7+107542769107542838107542182107542262107543922107543992-0.287000.000000.00000excludedHepG2U2AF2
SEDLDENSG00000091140.8chr7+107533644107533723107531608107531734107542182107542262-0.052000.000000.00000excludedK562AQR
SEDLDENSG00000091140.8chr7+107542769107542838107542182107542262107543922107543992-0.147000.000000.00000excludedK562U2AF1
SEDLDENSG00000091140.8chr7+107542769107542838107542206107542262107543922107543992-0.264000.000000.00000excludedK562U2AF2
A3SSDLDENSG00000091140.8chr7+1075457911075459491075458051075459491075453821075455030.069000.000000.00000longerK562AQR
MXEDLDENSG00000091140.8chr7+107533644107533723107542182107542262107531617107531734107543922107543992-0.479000.000000.000002includedHepG2U2AF1
MXEDLDENSG00000091140.8chr7+107533644107533723107542182107542262107531617107531734107543922107543992-0.160000.000000.000002includedK562U2AF1
MXEDLDENSG00000091140.8chr7+107533644107533723107542182107542262107531617107531734107543922107543992-0.142000.000040.004242includedK562SF3B1
MXEDLDENSG00000091140.8chr7+107533644107533723107542182107542262107531617107531734107543922107543992-0.065000.000000.000002includedK562AQR
MXEDLDENSG00000091140.8chr7+1075421821075422621075427691075428381075336441075337231075439221075439920.157000.000000.000161includedK562U2AF2
MXEDLDENSG00000091140.8chr7+1075421821075422621075427731075428381075316301075317341075439221075439920.276000.000000.000001includedK562U2AF2
MXEDLDENSG00000091140.8chr7+107533644107533723107542182107542262107531617107531734107543922107543992-0.290000.000000.000002includedK562U2AF2
MXEDLDENSG00000091140.8chr7+107542182107542262107542769107542838107533644107533723107543922107543992-0.097000.001060.036032includedK562DDX55
MXEDLDENSG00000091140.8chr7+107533644107533723107542182107542262107531617107531734107543922107543992-0.148000.000000.000002includedK562SF3B4
MXEDLDENSG00000091140.8chr7+107533644107533723107542182107542262107531617107531734107543922107543992-0.052000.000010.000392includedK562PRPF8
MXEDLDENSG00000091140.8chr7+1075458051075459491075467111075468131075454021075455031075559501075561410.124000.001730.033771includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DLD is not avaliable on ENCORE database.