USP54

General Information

Gene Name       : USP54
Gene ID             : ENSG00000166348.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: USP54)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878USP54ENSG00000166348.185.533.794.66ENCSR000AEF
HepG2USP54ENSG00000166348.1812.3012.1212.21ENCSR985KAT
K562USP54ENSG00000166348.1811.7614.5913.18ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for USP54 is not avaliable on ENCORE database.



Proteins bound to RNA
  • USP54 RNA is bound by 8 proteins.  







eCLIP assay for USP54 is not avaliable on ENCORE database.





8 proteins are bound to USP54 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr107525757975257673-3'-UTR,intron-Distal4.442894.25479HepG2PCBP2
chr107529598575296048-3'-UTR,CDS,intron-Distal,intron-Proximal4.464655.05356HepG2PRPF8
chr107538537575385482-5'-UTR,intron-Distal,intron-Proximal5.008788.12741HepG2GTF2F1
chr107538537175385445-5'-UTR,intron-Distal,intron-Proximal4.241254.27402K562CSTF2T
chr107538536775385450-5'-UTR,intron-Distal,intron-Proximal5.313346.73801K562GTF2F1
chr107538529975385435-5'-UTR,intron-Distal,intron-Proximal4.159044.14056K562EWSR1
chr107538539175385513-5'-UTR,intron-Distal,intron-Proximal4.646026.75874HepG2PRPF4
chr107538539575385470-5'-UTR,intron-Distal,intron-Proximal3.737616.59813HepG2FAM120A
chr107538555675385660-intron-Distal4.6203613.20532HepG2PRPF4
chr107538553375385649-intron-Distal4.3579113.51657HepG2FAM120A
chr107536454875364597-intron-Distal4.058893.28818K562LSM11
chr107538554075385638-intron-Distal5.002865.67757HepG2CSTF2T
chr107538522575385283-intron-Distal3.859703.03048HepG2GTF2F1
chr107538555675385656-intron-Distal4.557633.77881HepG2PCBP2
chr107538554375385649-intron-Distal6.0316011.81988K562GTF2F1
chr107538557375385661-intron-Distal4.924346.71013HepG2GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for USP54 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for USP54 is not available on ENCORE database.

  • 91 RBPs can affect the levels of USP54.  








The Knockdown/knockout RNA-Seq assay for USP54 is not available on ENCORE database.





91 RBPs can affect the gene expression of USP54 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
USP54ENSG00000166348.13756.07830443.474100.769608.271706.53330HepG2AATF
USP54ENSG00000166348.13490.96690712.04170-0.536303.512902.45590HepG2ABCF1
USP54ENSG00000166348.131069.59280437.067801.2910038.8380037.20680HepG2ACO1
USP54ENSG00000166348.13781.26290551.730900.501703.516302.34980HepG2AKAP8
USP54ENSG00000166348.13611.05180439.170300.476404.589203.62040HepG2AKAP8L
USP54ENSG00000166348.13274.69620401.59100-0.547903.168802.20510HepG2BCLAF1
USP54ENSG00000166348.13456.20390734.64900-0.687406.606805.72860HepG2BOP1
USP54ENSG00000166348.13460.80600696.56570-0.596105.634204.58460HepG2CALR
USP54ENSG00000166348.13363.33160516.53900-0.507602.116901.45380HepG2CNOT7
USP54ENSG00000166348.13299.22250674.44710-1.1725014.5053013.07880HepG2CPSF6
USP54ENSG00000166348.13446.54250586.32570-0.392902.559701.49680HepG2CPSF7
USP54ENSG00000166348.13335.02610550.29310-0.715907.780506.09280HepG2YBX3
USP54ENSG00000166348.13968.80970658.794500.556307.698106.72600HepG2CELF1
USP54ENSG00000166348.13488.72630708.32460-0.535406.692605.61330HepG2DAZAP1
USP54ENSG00000166348.13348.09130489.28210-0.491203.184402.46030HepG2DDX21
USP54ENSG00000166348.13293.51430490.09460-0.739605.246204.40820HepG2DDX3X
USP54ENSG00000166348.13666.55410454.490600.552402.905902.11600HepG2DDX55
USP54ENSG00000166348.13376.37430591.80880-0.653002.982901.93770HepG2DDX5
USP54ENSG00000166348.13301.46690418.17070-0.472102.697402.02770HepG2DKC1
USP54ENSG00000166348.13203.87410404.71910-0.989207.719006.76500HepG2EIF2S1
USP54ENSG00000166348.13188.71090447.26590-1.2450011.4525010.17920HepG2EIF4A3
USP54ENSG00000166348.13641.67930435.469100.559202.957002.24670HepG2EIF4B
USP54ENSG00000166348.13844.96380698.841200.273802.248401.47970HepG2EIF4G1
USP54ENSG00000166348.13311.68790669.43880-1.1028013.6046011.89270HepG2EIF4G2
USP54ENSG00000166348.131869.62480718.979301.3786023.6304021.79490HepG2FIP1L1
USP54ENSG00000166348.13274.24770675.60450-1.300706.879705.28640HepG2FTO
USP54ENSG00000166348.13604.39830451.261400.421402.387201.74270HepG2FXR1
USP54ENSG00000166348.13595.99460418.617000.509603.155502.44700HepG2G3BP1
USP54ENSG00000166348.13245.61660545.47920-1.1511013.0927011.85900HepG2HNRNPA1
USP54ENSG00000166348.13353.78920606.76620-0.778307.186406.10940HepG2HNRNPC
USP54ENSG00000166348.13570.84390839.19630-0.555907.208006.12110HepG2HNRNPF
USP54ENSG00000166348.13436.63530645.21700-0.563406.794805.78250HepG2HNRNPL
USP54ENSG00000166348.13708.15060496.031800.513504.265303.10960HepG2HNRNPM
USP54ENSG00000166348.13419.76920826.37030-0.9772015.3782013.82090HepG2IGF2BP1
USP54ENSG00000166348.13801.71670419.775200.933406.250804.72020HepG2METAP2
USP54ENSG00000166348.13956.67750581.842400.717308.638107.28240HepG2MSI2
USP54ENSG00000166348.13739.79750417.467500.825403.347502.13690HepG2NONO
USP54ENSG00000166348.13370.94880646.94140-0.802407.412506.22630HepG2NSUN2
USP54ENSG00000166348.13742.34760596.595500.315202.607301.78130HepG2PARN
USP54ENSG00000166348.13406.82180537.60380-0.402102.877302.12820HepG2PPIL4
USP54ENSG00000166348.13421.77370615.30300-0.544802.716501.50800HepG2PRPF6
USP54ENSG00000166348.13832.56400375.677201.1480024.1047022.79390HepG2PTBP1
USP54ENSG00000166348.13433.69920670.49020-0.628505.677604.86380HepG2PUF60
USP54ENSG00000166348.13630.41690406.854500.631706.210405.32660HepG2QKI
USP54ENSG00000166348.131043.78610564.794700.885905.897504.89510HepG2RAVER1
USP54ENSG00000166348.131624.94510698.423701.2181036.8434035.37490HepG2RBM22
USP54ENSG00000166348.13484.30080369.251600.391202.309401.68810HepG2RBM25
USP54ENSG00000166348.13635.52280418.087500.604006.211205.45510HepG2NELFE
USP54ENSG00000166348.13515.77160389.401000.405402.944302.31050HepG2RECQL
USP54ENSG00000166348.13474.54830903.99630-0.9298012.6486011.37720HepG2RPLP0
USP54ENSG00000166348.13358.46700518.81330-0.533402.751501.95410HepG2RPS3A
USP54ENSG00000166348.13889.40700575.322700.628405.453303.93010HepG2RPS5
USP54ENSG00000166348.13577.73190346.671900.736704.786803.78490HepG2RRP9
USP54ENSG00000166348.13323.49950536.76560-0.730508.881207.82750HepG2SAFB2
USP54ENSG00000166348.13342.05910488.54950-0.514302.753101.44640HepG2SART3
USP54ENSG00000166348.13513.53660391.117400.392802.737302.14860HepG2SF3B4
USP54ENSG00000166348.13529.89640642.92300-0.278902.030801.41220HepG2SLBP
USP54ENSG00000166348.13951.20980625.938100.6036010.527809.40520HepG2SMN1
USP54ENSG00000166348.131043.71070788.857200.403804.989204.37210HepG2SRFBP1
USP54ENSG00000166348.13640.38760408.246400.649407.379706.69360HepG2SRSF1
USP54ENSG00000166348.131293.27980777.060500.734806.447304.86220HepG2SRSF3
USP54ENSG00000166348.13462.84920824.47710-0.8329014.4854013.11190HepG2SRSF7
USP54ENSG00000166348.13484.55800332.134100.544805.123104.41430HepG2SRSF9
USP54ENSG00000166348.13429.32210684.93810-0.673908.884908.06690HepG2SSB
USP54ENSG00000166348.13958.47330752.893800.348203.954003.23430HepG2SUCLG1
USP54ENSG00000166348.13706.21600452.399200.642403.843303.06690HepG2SUPV3L1
USP54ENSG00000166348.13576.89210366.960300.652606.664405.85940HepG2TAF15
USP54ENSG00000166348.13436.69350303.203500.526202.399501.46320HepG2TFIP11
USP54ENSG00000166348.13369.38650585.60680-0.664806.238905.54230HepG2TIAL1
USP54ENSG00000166348.13431.54590590.92800-0.453504.377803.70060HepG2TRIM56
USP54ENSG00000166348.13839.33600615.010200.448503.024802.36880HepG2U2AF1
USP54ENSG00000166348.131249.75160582.519901.101203.638202.50300HepG2U2AF2
USP54ENSG00000166348.13875.78580502.574400.8011014.1561012.96140HepG2UTP3
USP54ENSG00000166348.13313.23470464.70960-0.569102.871301.74910HepG2XPO5
USP54ENSG00000166348.13281.68160445.33860-0.660804.570303.64730HepG2XRN2
USP54ENSG00000166348.13447.88500623.53870-0.477404.431803.61310HepG2ZC3H8
USP54ENSG00000166348.13786.15290952.61690-0.277102.391801.85750K562AGGF1
USP54ENSG00000166348.13761.23280991.22930-0.380902.959502.28350K562AKAP8L
USP54ENSG00000166348.13842.876801040.01590-0.303202.707901.80470K562ATP5C1
USP54ENSG00000166348.13747.36110918.88800-0.298102.798502.14220K562DDX47
USP54ENSG00000166348.13634.42170447.599700.503102.896801.83610K562EIF3D
USP54ENSG00000166348.13717.71010544.948600.397203.033701.70650K562EXOSC5
USP54ENSG00000166348.13582.48710789.61120-0.438903.361302.41950K562FIP1L1
USP54ENSG00000166348.13561.63350873.93990-0.637906.372905.21920K562GRSF1
USP54ENSG00000166348.13590.66740450.259600.391502.460301.89360K562HNRNPC
USP54ENSG00000166348.13382.37490532.38570-0.477502.895901.63230K562HNRNPK
USP54ENSG00000166348.13814.404801051.98330-0.369303.004502.14310K562KIF1C
USP54ENSG00000166348.13608.08020436.064200.479603.115701.62150K562LARP7
USP54ENSG00000166348.13630.15970456.698400.464402.968601.45600K562LIN28B
USP54ENSG00000166348.13900.06190753.199100.256902.393801.69510K562NSUN2
USP54ENSG00000166348.13611.73620896.34520-0.551104.894003.75540K562PPIG
USP54ENSG00000166348.13725.19790983.11170-0.439003.239202.65930K562PUS1
USP54ENSG00000166348.13771.12430957.82440-0.312802.600602.02330K562RBM15
USP54ENSG00000166348.13274.10170414.40070-0.596303.459102.54290K562RPS19
USP54ENSG00000166348.13720.88020533.295200.434703.524902.59800K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for USP54 is not available on ENCORE database.





5 RBPs can affect the splicing of USP54 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUSP54ENSG00000166348.13chr10-752646077526474875260412752605967526506575265184-0.483000.000830.06677excludedK562XRCC6
SEUSP54ENSG00000166348.13chr10-752943577529452875290461752905937529602675296195-0.606000.002030.02555excludedHepG2U2AF2
SEUSP54ENSG00000166348.13chr10-7529435775294528752904617529059375296026752961950.479000.000420.07930includedK562METAP2
SEUSP54ENSG00000166348.13chr10-752646077526474875260412752605967526506575265184-0.592000.000130.01264excludedHepG2NCBP2
A3SSUSP54ENSG00000166348.13chr10-7533117875331311753311787533127175335269753354620.178000.011580.05986longerK562AQR
MXEUSP54ENSG00000166348.13chr10-7530166175301727753025607530264375301390753014967530277575302889-0.140000.010390.065332includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for USP54 is not avaliable on ENCORE database.