METRN

General Information

Gene Name       : METRN
Gene ID             : ENSG00000103260.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: METRN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878METRNENSG00000103260.80.030.100.07ENCSR000AEF
HepG2METRNENSG00000103260.823.121.1012.11ENCSR985KAT
K562METRNENSG00000103260.86.302.024.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for METRN is not avaliable on ENCORE database.



Proteins bound to RNA
  • METRN RNA is bound by 10 proteins.  







eCLIP assay for METRN is not avaliable on ENCORE database.





10 proteins are bound to METRN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr16766901766965+3'-UTR,CDS,intron-Proximal4.986076.04760K562AQR
chr16767115767178+3'-UTR,CDS,intron-Proximal3.513785.40265K562METAP2
chr16767222767306+3'-UTR,CDS,intron-Distal,intron-Proximal3.054414.55339K562DDX55
chr16767262767359+3'-UTR,CDS,intron-Distal,intron-Proximal3.363924.11795K562YBX3
chr16767368767433+3'-UTR,CDS,intron-Proximal4.811513.62726K562DROSHA
chr16767850767894+3'-UTR3.721593.16310HepG2CSTF2T
chr16767279767354+3'-UTR,CDS,intron-Distal,intron-Proximal3.169403.04831K562RBM15
chr16765280765388+5'-UTR,CDS5.3466938.39081HepG2DDX3X
chr16765968765993+5'-UTR,CDS,intron-Proximal3.952656.95612HepG2PRPF8
chr16765983766043+5'-UTR,CDS,intron-Proximal4.860594.65563K562AQR
chr16765140765280+5'-UTR4.7924741.60681HepG2DDX3X
chr16765887765974+CDS4.558764.65678K562METAP2
chr16765642765707+CDS,intron-Distal4.9737511.01276HepG2DDX3X
chr16765993766040+intron-Proximal3.767907.29769HepG2PRPF8
chr16766004766070+intron-Proximal5.347576.71458K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for METRN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for METRN is not available on ENCORE database.

  • 66 RBPs can affect the levels of METRN.  








The Knockdown/knockout RNA-Seq assay for METRN is not available on ENCORE database.





66 RBPs can affect the gene expression of METRN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
METRNENSG00000103260.4242.29630124.922200.955604.750803.45840HepG2CCAR1
METRNENSG00000103260.497.5546062.001200.653801.884701.33590HepG2CELF1
METRNENSG00000103260.423.3982053.74480-1.199702.529801.65940HepG2DDX24
METRNENSG00000103260.4197.3908099.277000.991402.584601.98700HepG2DDX6
METRNENSG00000103260.4108.3690044.908801.270805.976805.07180HepG2DNAJC2
METRNENSG00000103260.4199.06250103.355100.945503.485802.62860HepG2FIP1L1
METRNENSG00000103260.441.3255094.94770-1.200104.004303.06600HepG2FUBP3
METRNENSG00000103260.489.2505045.191100.981702.790701.41150HepG2HNRNPA0
METRNENSG00000103260.4115.9973050.890201.188504.159503.32220HepG2HNRNPC
METRNENSG00000103260.4126.8690060.728601.062804.839503.96630HepG2HNRNPL
METRNENSG00000103260.4101.8713054.500700.902302.473101.31570HepG2HSPD1
METRNENSG00000103260.494.7272050.928300.895202.551201.41790HepG2KHDRBS1
METRNENSG00000103260.4296.85740131.973101.169407.507606.12760HepG2LARP4
METRNENSG00000103260.4119.5553038.639301.629403.468302.19830HepG2LARP7
METRNENSG00000103260.4241.29000107.002801.173002.939802.29200HepG2MATR3
METRNENSG00000103260.4175.9164066.106801.411909.502308.11470HepG2NOL12
METRNENSG00000103260.428.1585070.27860-1.319502.959102.18590HepG2NSUN2
METRNENSG00000103260.4157.6857088.902300.826703.993803.29210HepG2PCBP1
METRNENSG00000103260.4222.3428090.471501.2972010.328509.40240HepG2PTBP1
METRNENSG00000103260.4126.9831063.104601.008703.977903.27790HepG2PUF60
METRNENSG00000103260.4301.5324066.988202.1702031.7422030.18230HepG2PUM1
METRNENSG00000103260.4120.3074046.602501.368102.704001.72180HepG2RBM27
METRNENSG00000103260.4267.21040100.677701.4081012.2760011.29060HepG2NELFE
METRNENSG00000103260.495.6356043.582601.133703.516302.83200HepG2RPS19
METRNENSG00000103260.4141.3960042.962801.718503.132702.28030HepG2RPS2
METRNENSG00000103260.4180.5042081.974801.138704.611703.72860HepG2SF3A3
METRNENSG00000103260.4166.9859094.174400.826203.818503.14180HepG2SF3B4
METRNENSG00000103260.478.9910025.499301.631102.900501.41110HepG2SFPQ
METRNENSG00000103260.4110.8664052.508501.078104.434203.65430HepG2SMN1
METRNENSG00000103260.4107.4272040.199401.418002.594501.66860HepG2SMNDC1
METRNENSG00000103260.434.3293087.28560-1.346303.506602.62190HepG2SNRNP70
METRNENSG00000103260.4127.52670242.11080-0.924904.034703.46340HepG2SRFBP1
METRNENSG00000103260.4262.4026062.306402.0742010.645309.52420HepG2SRSF5
METRNENSG00000103260.471.94450210.18390-1.546708.631507.82480HepG2SSB
METRNENSG00000103260.490.7825046.676600.959602.982601.83530HepG2STIP1
METRNENSG00000103260.4161.1083070.859701.184906.911706.00640HepG2SUCLG1
METRNENSG00000103260.428.4386088.38090-1.635906.098205.32010HepG2TAF15
METRNENSG00000103260.4109.9720049.138001.162101.944301.50950HepG2TIAL1
METRNENSG00000103260.4161.9497049.560901.708205.837905.07270HepG2TRIM56
METRNENSG00000103260.4135.1676061.650301.132504.905603.70910HepG2TUFM
METRNENSG00000103260.438.1169088.37570-1.213203.328502.64520HepG2U2AF1
METRNENSG00000103260.4132.8510065.255701.025503.115702.22820HepG2UBE2L3
METRNENSG00000103260.4175.5105043.967301.9970012.6791011.07920HepG2UCHL5
METRNENSG00000103260.4125.1545070.187800.834303.230502.59210HepG2UTP3
METRNENSG00000103260.4215.77280110.186700.969506.407605.59650K562AGGF1
METRNENSG00000103260.4201.94090121.095900.737703.998002.77160K562AKAP8
METRNENSG00000103260.4236.61110114.658601.045102.571901.94110K562AKAP8L
METRNENSG00000103260.4152.77590271.84120-0.831304.717303.98830K562AQR
METRNENSG00000103260.4174.92580120.312500.539902.214701.40590K562ATP5C1
METRNENSG00000103260.4159.4330096.823300.719402.949001.85390K562CCAR1
METRNENSG00000103260.4203.3884079.636501.352606.996905.20150K562CSTF2
METRNENSG00000103260.42.2469023.34530-3.377104.252903.33310K562G3BP2
METRNENSG00000103260.4450.29700224.607001.003406.900405.69960K562GRSF1
METRNENSG00000103260.4274.78910167.398300.714904.378403.01290K562HNRNPL
METRNENSG00000103260.4115.9500045.367701.353705.112603.54070K562IGF2BP2
METRNENSG00000103260.4124.0805047.695301.379306.805905.45890K562MAGOH
METRNENSG00000103260.4112.9834047.601001.246902.647801.74670K562MATR3
METRNENSG00000103260.458.14460110.98460-0.932602.407401.66200K562POLR2G
METRNENSG00000103260.4203.63440111.667100.866704.662003.55750K562PPIG
METRNENSG00000103260.4152.2646088.356900.785102.759601.85720K562PSIP1
METRNENSG00000103260.4148.0939046.337801.6762010.963509.70430K562PTBP1
METRNENSG00000103260.4177.86650113.679400.645702.527402.00310K562PUS1
METRNENSG00000103260.4189.57630110.788700.774904.058203.35680K562RBM15
METRNENSG00000103260.487.8442044.441000.983003.134602.23410K562RBM22
METRNENSG00000103260.4129.6764076.479100.761702.475401.51750K562SRFBP1
METRNENSG00000103260.4133.43530203.59830-0.609602.911801.95510K562SRPK2
METRNENSG00000103260.4145.7837045.424801.682209.550408.24820K562SRSF1
METRNENSG00000103260.488.7077042.895901.048103.417902.22950K562SRSF5
METRNENSG00000103260.4158.0515045.976601.781307.157505.96180K562TARDBP
METRNENSG00000103260.4105.9048044.348601.255704.922003.78350K562TIA1
METRNENSG00000103260.4151.1877090.354100.742602.711001.77560K562TRIM56
METRNENSG00000103260.46.1413023.38390-1.928902.471301.71140K562U2AF2
METRNENSG00000103260.4107.22610189.99430-0.825304.748103.66610K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for METRN is not available on ENCORE database.





1 RBPs can affect the splicing of METRN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIMETRNENSG00000103260.4chr16+7669427671357669427669927670707671350.425000.000010.00316includedK562ZC3H8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for METRN is not avaliable on ENCORE database.