TMEM168

General Information

Gene Name       : TMEM168
Gene ID             : ENSG00000146802.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM168)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM168ENSG00000146802.1213.1313.5113.32ENCSR000AEF
HepG2TMEM168ENSG00000146802.128.358.058.20ENCSR985KAT
K562TMEM168ENSG00000146802.1215.0013.2414.12ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM168 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM168 RNA is bound by 7 proteins.  







eCLIP assay for TMEM168 is not avaliable on ENCORE database.





7 proteins are bound to TMEM168 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7112424979112425068-5'-UTR,intron-Distal,intron-Proximal4.615753.42835K562SF3B4
chr7112430191112430281-5'-UTR,intron-Distal3.312935.58962K562RBM15
chr7112417962112418019-intron-Distal3.781974.88448HepG2HNRNPL
chr7112422652112422706-intron-Distal4.524068.30916K562HNRNPM
chr7112423627112423662-intron-Distal,intron-Proximal3.088783.38150K562KHSRP
chr7112422706112422756-intron-Distal5.6111910.81162K562HNRNPM
chr7112415450112415478-intron-Distal,intron-Proximal3.333947.01633K562KHSRP
chr7112421528112421547-intron-Distal3.846053.01445K562EXOSC5
chr7112422867112422917-intron-Distal3.194224.46810K562EXOSC5
chr7112430101112430207-intron-Distal3.439618.16971K562EFTUD2
chr7112407802112407856-intron-Distal5.230165.40008K562SF3B4
chr7112417903112417967-intron-Distal3.061573.71976K562HNRNPL
chr7112422456112422472-intron-Distal3.325733.14999K562EXOSC5
chr7112415421112415450-intron-Distal,intron-Proximal3.804547.12499K562KHSRP
chr7112422593112422652-intron-Distal4.903675.31505K562HNRNPM
chr7112422975112423048-intron-Distal3.441265.10669K562HNRNPM
chr7112417775112417882-intron-Distal3.382137.09109K562HNRNPL
chr7112422670112422751-intron-Distal3.2476310.44814K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM168 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM168 is not available on ENCORE database.

  • 61 RBPs can affect the levels of TMEM168.  








The Knockdown/knockout RNA-Seq assay for TMEM168 is not available on ENCORE database.





61 RBPs can affect the gene expression of TMEM168 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM168ENSG00000146802.8158.80190294.29720-0.890004.709103.50740HepG2ABCF1
TMEM168ENSG00000146802.8357.86390518.32770-0.534502.756602.22600HepG2AKAP1
TMEM168ENSG00000146802.8202.65510351.15760-0.793103.089602.27820HepG2CNOT7
TMEM168ENSG00000146802.8119.49730188.60300-0.658402.526101.49490HepG2CSTF2
TMEM168ENSG00000146802.8279.75570412.97420-0.561904.501003.71610HepG2CELF1
TMEM168ENSG00000146802.8305.21360444.10290-0.541105.154604.18890HepG2DAZAP1
TMEM168ENSG00000146802.8366.14390240.301600.607503.921702.82180HepG2DDX24
TMEM168ENSG00000146802.8188.24250300.11230-0.672902.637201.87970HepG2DDX55
TMEM168ENSG00000146802.8171.32070238.72540-0.478702.579101.94530HepG2DNAJC2
TMEM168ENSG00000146802.8230.94240441.17600-0.933805.797204.82690HepG2EIF4B
TMEM168ENSG00000146802.8161.00490278.20230-0.789005.128803.99450HepG2EWSR1
TMEM168ENSG00000146802.8300.31120217.116800.467902.070701.38280HepG2FUBP3
TMEM168ENSG00000146802.8314.61050457.12170-0.539002.962802.24570HepG2FXR1
TMEM168ENSG00000146802.8285.32940424.13470-0.571903.202902.48990HepG2G3BP1
TMEM168ENSG00000146802.8145.74670246.79890-0.759903.525102.81100HepG2GPKOW
TMEM168ENSG00000146802.8339.27620235.524100.526502.578401.96710HepG2HNRNPLL
TMEM168ENSG00000146802.8185.99570268.70660-0.530803.059002.42420HepG2HNRNPU
TMEM168ENSG00000146802.8274.94950431.15470-0.649002.595601.93980HepG2IGF2BP2
TMEM168ENSG00000146802.8301.23650459.86690-0.610303.389802.69820HepG2MATR3
TMEM168ENSG00000146802.8172.90500333.73160-0.948705.827203.75260HepG2NKRF
TMEM168ENSG00000146802.8533.64790423.153600.334602.277501.71650HepG2PCBP1
TMEM168ENSG00000146802.8340.58460430.56690-0.338201.886601.41790HepG2PTBP1
TMEM168ENSG00000146802.8273.30460420.35530-0.621104.481603.74330HepG2PUF60
TMEM168ENSG00000146802.8431.90600288.018700.584502.280201.63610HepG2RAVER1
TMEM168ENSG00000146802.8350.42930457.05690-0.383302.278901.79610HepG2RBM22
TMEM168ENSG00000146802.8606.96860423.219100.520104.063703.26010HepG2RBM25
TMEM168ENSG00000146802.8207.27350329.62850-0.669303.533002.40480HepG2RBM27
TMEM168ENSG00000146802.8313.93990479.18600-0.610105.210504.50620HepG2NELFE
TMEM168ENSG00000146802.8100.79370199.84290-0.987502.441101.85930HepG2RPS19
TMEM168ENSG00000146802.8134.10530304.01380-1.180808.815007.44850HepG2RPS2
TMEM168ENSG00000146802.8191.21180279.07550-0.545503.452602.74670HepG2SMN1
TMEM168ENSG00000146802.8395.85910516.22300-0.383002.807302.30310HepG2SRFBP1
TMEM168ENSG00000146802.8287.47100415.01850-0.529804.234403.48870HepG2SRSF5
TMEM168ENSG00000146802.8381.34340472.00850-0.307702.015201.46820HepG2SUCLG1
TMEM168ENSG00000146802.8202.01320263.43020-0.383001.983501.49080HepG2TRIM56
TMEM168ENSG00000146802.8713.986001081.49520-0.599105.923304.13310K562ABCF1
TMEM168ENSG00000146802.81197.358101538.84610-0.362002.965701.68050K562APOBEC3C
TMEM168ENSG00000146802.8792.867001539.18750-0.9570015.6601014.41850K562AQR
TMEM168ENSG00000146802.8202.80060337.74620-0.735904.930603.42930K562CCAR1
TMEM168ENSG00000146802.8651.51230960.40760-0.559902.622901.59470K562CNOT7
TMEM168ENSG00000146802.8347.63040605.79890-0.801305.372804.28870K562CPSF6
TMEM168ENSG00000146802.8449.46660723.73910-0.687306.047004.65330K562EFTUD2
TMEM168ENSG00000146802.8586.94670910.76400-0.633806.923005.63220K562EIF4A3
TMEM168ENSG00000146802.8637.06370820.15960-0.364503.311102.02310K562EIF4B
TMEM168ENSG00000146802.8602.75310794.98250-0.399403.224301.80850K562EWSR1
TMEM168ENSG00000146802.8380.91700585.94900-0.621305.709003.84490K562EXOSC5
TMEM168ENSG00000146802.8762.66500947.15030-0.312502.801902.19340K562FXR1
TMEM168ENSG00000146802.81458.08470984.161500.567003.568502.74080K562G3BP2
TMEM168ENSG00000146802.8430.38190578.41470-0.426502.321201.59320K562GPKOW
TMEM168ENSG00000146802.8840.062001115.94690-0.409702.416401.43690K562HNRNPL
TMEM168ENSG00000146802.8476.26680639.52200-0.425202.354401.49940K562HNRNPM
TMEM168ENSG00000146802.8702.091201052.31830-0.583807.962906.45240K562HNRNPU
TMEM168ENSG00000146802.8816.345001204.29930-0.560906.503205.18530K562MAGOH
TMEM168ENSG00000146802.8413.35320564.58640-0.449802.210601.42770K562METAP2
TMEM168ENSG00000146802.8707.78140953.45800-0.429906.023804.98170K562NSUN2
TMEM168ENSG00000146802.8649.459101071.59890-0.722509.039807.23960K562PCBP2
TMEM168ENSG00000146802.8688.73150882.64210-0.357902.401801.64010K562PPIG
TMEM168ENSG00000146802.8534.44790704.27890-0.398102.281601.59790K562PRPF8
TMEM168ENSG00000146802.81302.692801902.79620-0.546606.294705.06760K562PUF60
TMEM168ENSG00000146802.8766.060001122.12430-0.550705.661604.40630K562RBM22
TMEM168ENSG00000146802.8389.82770509.40830-0.386002.289401.39180K562RCC2
TMEM168ENSG00000146802.8612.06090940.82700-0.620308.617007.23650K562SF3A3
TMEM168ENSG00000146802.8608.131501023.97360-0.751708.755807.18660K562SF3B4
TMEM168ENSG00000146802.8923.119401146.96940-0.313202.468801.79450K562SRSF1
TMEM168ENSG00000146802.8863.881601160.90160-0.426303.410902.62200K562TARDBP
TMEM168ENSG00000146802.8890.934101119.79600-0.329802.681001.87640K562TIA1
TMEM168ENSG00000146802.8380.73010537.10590-0.496402.937001.97140K562TIAL1
TMEM168ENSG00000146802.8437.93460570.52860-0.381602.298601.44880K562TRIM56
TMEM168ENSG00000146802.81215.43800985.736700.302102.642201.85620K562U2AF2
TMEM168ENSG00000146802.8695.783401010.97210-0.539008.032906.88840K562UPF1
TMEM168ENSG00000146802.8546.41530734.86510-0.427502.684901.50080K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM168 is not available on ENCORE database.





5 RBPs can affect the splicing of TMEM168 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM168ENSG00000146802.8chr7-1124285081124285991124237521124250081124302141124304480.307000.000000.00020includedK562SRSF1
SETMEM168ENSG00000146802.8chr7-1124285081124285991124237521124250081124302141124304480.289000.000390.07613includedK562METAP2
SETMEM168ENSG00000146802.8chr7-112423752112425008112402436112407799112430214112430647-0.188000.004730.05963excludedK562PUS1
SETMEM168ENSG00000146802.8chr7-112428508112428599112423752112425008112430214112430448-0.142000.001300.07722excludedK562HNRNPUL1
SETMEM168ENSG00000146802.8chr7-1124285081124285991124237521124250081124302141124304480.209000.002900.04555includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM168 is not avaliable on ENCORE database.