PARP3

General Information

Gene Name       : PARP3
Gene ID             : ENSG00000041880.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PARP3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PARP3ENSG00000041880.144.9313.599.26ENCSR000AEF
HepG2PARP3ENSG00000041880.1414.349.1811.76ENCSR985KAT
K562PARP3ENSG00000041880.143.843.003.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PARP3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PARP3 RNA is bound by 3 proteins.  







eCLIP assay for PARP3 is not avaliable on ENCORE database.





3 proteins are bound to PARP3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr35197951051979559+3'-UTR,CDS,intron-Proximal4.747104.08604HepG2PPIG
chr35197951251979570+3'-UTR,CDS4.049053.79347HepG2GRWD1
chr35197854751978648+5'-UTR,CDS,intron-Proximal4.073683.31283K562PRPF8
chr35197854451978652+5'-UTR,CDS,intron-Proximal4.0820613.03969HepG2PRPF8
chr35197889951978965+5'-UTR,CDS,intron-Proximal3.854963.86355HepG2PPIG
chr35197755151977602+5'-UTR,CDS,intron-Proximal4.133947.38067HepG2PRPF8
chr35197893451979000+intron-Proximal4.132105.93840HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PARP3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PARP3 is not available on ENCORE database.

  • 76 RBPs can affect the levels of PARP3.  








The Knockdown/knockout RNA-Seq assay for PARP3 is not available on ENCORE database.





76 RBPs can affect the gene expression of PARP3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PARP3ENSG00000041880.10788.99630499.589100.659205.192803.77950HepG2AKAP8
PARP3ENSG00000041880.10761.35390448.184900.764406.462205.28520HepG2ASCC1
PARP3ENSG00000041880.10708.05360468.014600.597207.269606.24330HepG2AUH
PARP3ENSG00000041880.10527.03940336.318900.648003.830502.72720HepG2BCCIP
PARP3ENSG00000041880.10420.56020292.234300.525102.733901.83960HepG2BCLAF1
PARP3ENSG00000041880.10573.12730430.574000.412502.503201.33080HepG2BUD13
PARP3ENSG00000041880.10767.28420540.417100.505603.439102.68050HepG2CPSF6
PARP3ENSG00000041880.10754.97950429.246900.8145013.2544012.05290HepG2CELF1
PARP3ENSG00000041880.10615.02310269.151501.1921015.7243014.26660HepG2DDX21
PARP3ENSG00000041880.10813.79210330.671601.2992015.0701013.45590HepG2DDX55
PARP3ENSG00000041880.10688.84940445.936000.627303.943403.21600HepG2DDX6
PARP3ENSG00000041880.10450.80150291.931900.626804.882403.97240HepG2DNAJC21
PARP3ENSG00000041880.10382.04780289.387700.400602.779602.12650HepG2DNAJC2
PARP3ENSG00000041880.10466.37940344.081100.438702.265101.42900HepG2EEF2
PARP3ENSG00000041880.10623.72350428.438700.541703.100502.47390HepG2EIF2S1
PARP3ENSG00000041880.10361.77470254.339600.508203.086701.94960HepG2EIF3G
PARP3ENSG00000041880.10678.67950473.354100.519702.789502.14780HepG2EIF4A3
PARP3ENSG00000041880.10848.60810537.320300.659209.253308.26030HepG2ETF1
PARP3ENSG00000041880.101002.48880580.383500.788406.988005.82320HepG2FIP1L1
PARP3ENSG00000041880.101018.57340541.328000.911904.224702.97150HepG2FTO
PARP3ENSG00000041880.10386.59810248.731100.636104.003902.91370HepG2GEMIN5
PARP3ENSG00000041880.10473.39590266.957600.826306.408604.83540HepG2GNB2L1
PARP3ENSG00000041880.10915.19890612.625200.579004.461503.66140HepG2GPKOW
PARP3ENSG00000041880.10509.86880294.729100.790606.913305.96040HepG2HNRNPA1
PARP3ENSG00000041880.10527.16100420.283500.326802.788802.11290HepG2HNRNPL
PARP3ENSG00000041880.10804.50120584.637700.460503.200102.52960HepG2HNRNPLL
PARP3ENSG00000041880.10585.37640325.674400.8458012.0051010.81550HepG2HNRNPU
PARP3ENSG00000041880.10704.80840450.420300.645904.552703.70550HepG2IGF2BP2
PARP3ENSG00000041880.10468.60580332.663700.494204.550603.62930HepG2ILF2
PARP3ENSG00000041880.10477.34500377.702700.337702.452401.49150HepG2KIF1C
PARP3ENSG00000041880.10906.49120644.588700.491802.483101.69790HepG2LARP4
PARP3ENSG00000041880.10492.07580292.382600.750902.768101.71510HepG2METAP2
PARP3ENSG00000041880.10663.99350469.638800.499503.750502.81180HepG2MSI2
PARP3ENSG00000041880.10647.65400457.552500.501202.634601.89070HepG2NOL12
PARP3ENSG00000041880.10503.22390303.643900.728703.144801.97500HepG2NONO
PARP3ENSG00000041880.10661.94190437.954700.595803.867803.02490HepG2PABPC4
PARP3ENSG00000041880.10433.82430286.315700.599402.998801.91840HepG2PCBP2
PARP3ENSG00000041880.10565.27350413.920300.449503.849402.95000HepG2PRPF4
PARP3ENSG00000041880.10406.56410255.085600.672404.024803.07280HepG2PRPF8
PARP3ENSG00000041880.10614.05650436.808000.491303.964903.26550HepG2PUF60
PARP3ENSG00000041880.10582.86090463.730900.329802.894602.29160HepG2PUM1
PARP3ENSG00000041880.10593.46800449.105100.402002.389501.89870HepG2RBM22
PARP3ENSG00000041880.10325.94910454.00190-0.478102.965602.27090HepG2RBM25
PARP3ENSG00000041880.10862.00630537.318600.681807.259506.23110HepG2RPLP0
PARP3ENSG00000041880.10604.37050271.788901.1528015.4178014.12920HepG2RPS19
PARP3ENSG00000041880.10507.71350290.863800.803606.440205.25030HepG2RPS2
PARP3ENSG00000041880.10388.49000244.959400.665203.498102.59730HepG2RPS3A
PARP3ENSG00000041880.10442.52140296.910400.575603.367902.18010HepG2RPS5
PARP3ENSG00000041880.10395.04430272.826600.533903.053302.06410HepG2SERBP1
PARP3ENSG00000041880.10400.46320549.07420-0.455302.352301.73180HepG2SF3A3
PARP3ENSG00000041880.10549.00450338.202300.698808.839007.79300HepG2SMN1
PARP3ENSG00000041880.10452.28650282.183100.680504.078502.89670HepG2SMNDC1
PARP3ENSG00000041880.10881.85450643.887100.453602.177401.48790HepG2SNRNP70
PARP3ENSG00000041880.10697.70340507.256200.459804.873704.26240HepG2SRFBP1
PARP3ENSG00000041880.10318.15010501.94830-0.657805.985505.35590HepG2SRSF1
PARP3ENSG00000041880.10622.38710431.332100.528906.047105.17380HepG2SRSF5
PARP3ENSG00000041880.10662.12390440.433400.588107.206106.45370HepG2SSB
PARP3ENSG00000041880.10735.54370490.502500.584503.035502.38930HepG2SUCLG1
PARP3ENSG00000041880.10714.01830329.178201.1170011.135609.92880HepG2SUPV3L1
PARP3ENSG00000041880.10325.60990451.21630-0.470703.165902.57160HepG2TAF15
PARP3ENSG00000041880.10741.81350316.411701.2292021.1214019.97890HepG2TIAL1
PARP3ENSG00000041880.10500.89210319.285100.649606.936506.11380HepG2TRIM56
PARP3ENSG00000041880.10761.67910496.431600.617504.792003.97840HepG2U2AF1
PARP3ENSG00000041880.10964.54730368.542301.387905.201603.81950HepG2U2AF2
PARP3ENSG00000041880.10668.31820451.812600.564703.831502.84020HepG2UBE2L3
PARP3ENSG00000041880.10799.57960486.945900.7154011.4734010.22730HepG2UPF1
PARP3ENSG00000041880.10313.12860470.12550-0.586304.838404.08260HepG2UTP3
PARP3ENSG00000041880.10812.50120535.545800.601309.483708.62430HepG2ZNF622
PARP3ENSG00000041880.1075.96640160.25790-1.077005.375904.62670K562AGGF1
PARP3ENSG00000041880.1083.27730141.67460-0.766602.678902.09880K562AQR
PARP3ENSG00000041880.10276.05210191.523000.527302.706701.54640K562CCDC124
PARP3ENSG00000041880.10175.60840254.21000-0.533702.279501.39430K562CELF1
PARP3ENSG00000041880.10161.3605092.156000.808002.303001.39440K562EIF3A
PARP3ENSG00000041880.1075.86050159.61310-1.073203.313701.94260K562HNRNPA2B1
PARP3ENSG00000041880.10223.48460120.528200.890705.767104.46410K562HNRNPU
PARP3ENSG00000041880.1039.9758075.52510-0.917802.100701.44310K562PRPF8
PARP3ENSG00000041880.10136.23260225.60620-0.727703.154002.28500K562PUF60
PARP3ENSG00000041880.1070.62140165.38710-1.227705.533404.79700K562PUS1
PARP3ENSG00000041880.1086.05120161.13400-0.905004.136703.42770K562RBM15
PARP3ENSG00000041880.10122.7378063.486600.951002.754801.75410K562RPS3
PARP3ENSG00000041880.1017.8066062.64390-1.814805.165704.20420K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PARP3 is not available on ENCORE database.





2 RBPs can affect the splicing of PARP3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPARP3ENSG00000041880.10chr3+519769455197706251976360519767245197736451977554-0.493000.001360.02666excludedHepG2U2AF1
SEPARP3ENSG00000041880.10chr3+5197694551977062519763605197672451977364519775540.504000.000020.00838includedHepG2DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PARP3 is not avaliable on ENCORE database.