IDH2

General Information

Gene Name       : IDH2
Gene ID             : ENSG00000182054.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: IDH2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878IDH2ENSG00000182054.990.13161.70125.91ENCSR000AEF
HepG2IDH2ENSG00000182054.9101.3860.9081.14ENCSR985KAT
K562IDH2ENSG00000182054.959.9656.7558.36ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for IDH2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • IDH2 RNA is bound by 17 proteins.  







eCLIP assay for IDH2 is not avaliable on ENCORE database.





17 proteins are bound to IDH2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr159063034390630347-3'-UTR,CDS,intron-Distal,intron-Proximal3.672896.00726K562YBX3
chr159062676790626903-3'-UTR,intron-Distal3.995564.66555K562FAM120A
chr159062692690627036-3'-UTR,intron-Distal4.1083813.86833K562UPF1
chr159062736490627381-3'-UTR,intron-Distal,intron-Proximal3.376453.31306K562NOLC1
chr159063182390631882-3'-UTR,CDS,intron-Distal,intron-Proximal3.749283.02919K562GRWD1
chr159062822990628298-3'-UTR,CDS,intron-Distal,intron-Proximal3.005163.47879HepG2PPIG
chr159063037490630386-3'-UTR,CDS,intron-Distal4.099993.35417K562METAP2
chr159062741590627474-3'-UTR,intron-Distal3.821285.47244HepG2LARP4
chr159062712890627191-3'-UTR,intron-Distal,intron-Proximal3.014015.07504K562UPF1
chr159063186190631940-3'-UTR,CDS,intron-Distal4.2624612.06791K562METAP2
chr159063078190630806-3'-UTR,CDS,intron-Distal3.239799.72633K562YBX3
chr159062735290627377-3'-UTR,intron-Distal,intron-Proximal5.8913239.93712HepG2SUB1
chr159062726190627335-3'-UTR,intron-Distal,intron-Proximal5.0507330.39332K562NOLC1
chr159062726590627291-3'-UTR,intron-Distal3.3705413.49497K562YBX3
chr159063068890630716-3'-UTR,CDS,intron-Distal3.349049.21976K562YBX3
chr159062724390627256-3'-UTR,intron-Distal,intron-Proximal3.642298.04783K562YBX3
chr159062730590627415-3'-UTR,intron-Distal,intron-Proximal4.1343619.20984K562PABPC4
chr159062669790626759-3'-UTR,intron-Distal3.404178.16191K562UPF1
chr159062856390628618-3'-UTR,CDS,intron-Distal3.614914.97821K562BUD13
chr159062662790626676-3'-UTR,intron-Distal4.977916.02674K562UPF1
chr159062806990628137-3'-UTR,CDS,intron-Distal,intron-Proximal3.016264.13990HepG2LARP4
chr159062724190627327-3'-UTR,intron-Distal,intron-Proximal8.10773120.98668HepG2SUB1
chr159062733590627364-3'-UTR,intron-Distal,intron-Proximal4.2507716.55843K562NOLC1
chr159062732790627352-3'-UTR,intron-Distal,intron-Proximal6.8270587.54500HepG2SUB1
chr159064552490645576-5'-UTR,CDS,intron-Distal3.795425.37959K562GEMIN5
chr159064552290645644-5'-UTR,CDS,intron-Distal4.2265717.06640HepG2DDX3X
chr159063478590634795-CDS,intron-Distal3.322383.25727K562METAP2
chr159063479490634814-CDS,intron-Distal3.417469.73440K562LIN28B
chr159063377190633839-CDS,intron-Distal4.486297.94690K562METAP2
chr159063372990633838-CDS,intron-Distal3.545154.72530HepG2G3BP1
chr159063478490634811-CDS,intron-Distal,intron-Proximal4.3661918.09145K562YBX3
chr159063386790633876-CDS,intron-Distal3.7664117.08445K562YBX3
chr159063478390634794-CDS,intron-Distal,intron-Proximal4.2825415.19015K562LIN28B
chr159063364790633716-CDS,intron-Distal,intron-Proximal4.388896.99120K562AQR
chr159063384290633870-CDS,intron-Distal3.226729.60126K562LIN28B
chr159063384390633867-CDS,intron-Distal3.6043118.80922K562YBX3
chr159064170090641787-intron-Distal4.174614.50052K562HNRNPL
chr159063471690634777-intron-Distal,intron-Proximal4.473854.98250K562AQR
chr159064174490641817-intron-Distal4.175103.98095HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for IDH2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for IDH2 is not available on ENCORE database.

  • 127 RBPs can affect the levels of IDH2.  








The Knockdown/knockout RNA-Seq assay for IDH2 is not available on ENCORE database.





127 RBPs can affect the gene expression of IDH2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
IDH2ENSG00000182054.51057.278601446.97600-0.452704.340503.02610HepG2AATF
IDH2ENSG00000182054.51707.820802625.79610-0.6206012.2229011.13730HepG2ACO1
IDH2ENSG00000182054.51471.414202701.33620-0.8765011.2324010.22980HepG2AKAP1
IDH2ENSG00000182054.52440.694101913.894600.350702.274701.32480HepG2AKAP8
IDH2ENSG00000182054.51483.287902234.99840-0.591506.450505.27450HepG2ASCC1
IDH2ENSG00000182054.52931.070003510.47910-0.260203.581302.81700HepG2AUH
IDH2ENSG00000182054.5576.592901522.11060-1.4004031.6804030.03640HepG2BOP1
IDH2ENSG00000182054.51162.950701563.61710-0.427104.733103.75850HepG2CALR
IDH2ENSG00000182054.53685.032002685.413200.456402.510601.58790HepG2CCAR1
IDH2ENSG00000182054.51815.560401397.345700.377603.146702.41900HepG2CPSF6
IDH2ENSG00000182054.51104.221402481.25290-1.1680044.0022042.07520HepG2CELF1
IDH2ENSG00000182054.52022.482102428.30290-0.263803.258402.36050HepG2DDX19B
IDH2ENSG00000182054.52095.601301595.616400.393203.919103.12600HepG2DDX21
IDH2ENSG00000182054.51169.288501562.12720-0.417904.436103.26910HepG2DDX24
IDH2ENSG00000182054.52881.319702223.286100.373902.595201.99640HepG2DDX6
IDH2ENSG00000182054.51661.802001396.759900.250602.479401.80970HepG2DNAJC21
IDH2ENSG00000182054.5444.689901543.86810-1.7957045.4356041.91920HepG2EFTUD2
IDH2ENSG00000182054.51099.127001469.91440-0.419402.568901.50810HepG2AGO1
IDH2ENSG00000182054.53181.430502136.644000.574206.372805.49300HepG2EIF2S1
IDH2ENSG00000182054.5843.864001503.42540-0.8332010.045508.43050HepG2EIF3D
IDH2ENSG00000182054.51068.394801507.26490-0.496506.027004.52200HepG2EIF3G
IDH2ENSG00000182054.51487.078702299.29740-0.628704.490303.62510HepG2EIF4B
IDH2ENSG00000182054.52032.933602632.07660-0.372606.112004.95550HepG2EIF4G1
IDH2ENSG00000182054.51425.535704030.51930-1.4995093.6803091.16080HepG2ETF1
IDH2ENSG00000182054.51314.079002565.52000-0.9652021.1950019.06760HepG2EWSR1
IDH2ENSG00000182054.51606.931002835.62100-0.819405.369004.32660HepG2FIP1L1
IDH2ENSG00000182054.5682.700401399.81310-1.035905.437404.01940HepG2FTO
IDH2ENSG00000182054.51177.215101972.72580-0.7448012.6401011.01800HepG2FUBP3
IDH2ENSG00000182054.51082.947701648.94830-0.606604.308102.92990HepG2FUS
IDH2ENSG00000182054.51131.678502210.10920-0.9657012.6781011.30830HepG2G3BP1
IDH2ENSG00000182054.52653.444901583.905000.744309.092507.97380HepG2GPKOW
IDH2ENSG00000182054.51021.985901581.87070-0.630303.571901.97300HepG2HLTF
IDH2ENSG00000182054.51438.475202239.11300-0.638405.618404.65100HepG2HNRNPK
IDH2ENSG00000182054.51211.125801558.13890-0.363505.152604.34570HepG2HNRNPU
IDH2ENSG00000182054.51560.303002083.39470-0.417102.916101.64870HepG2HSPD1
IDH2ENSG00000182054.51618.130402246.34830-0.473304.388703.55520HepG2IGF2BP2
IDH2ENSG00000182054.51316.321002108.82340-0.679902.175201.31170HepG2IGF2BP3
IDH2ENSG00000182054.52018.472701335.623700.595703.696402.13930HepG2ILF3
IDH2ENSG00000182054.51373.053502397.05650-0.803909.838208.70550HepG2MATR3
IDH2ENSG00000182054.5993.306401573.39690-0.663604.297103.00080HepG2METAP2
IDH2ENSG00000182054.51786.331902293.89230-0.360802.446001.68340HepG2MSI2
IDH2ENSG00000182054.51675.029202453.39390-0.550605.435904.56230HepG2NCBP2
IDH2ENSG00000182054.52069.318001340.354700.626408.135206.90160HepG2NSUN2
IDH2ENSG00000182054.51442.653302400.22440-0.7344021.6597020.22210HepG2PCBP1
IDH2ENSG00000182054.51933.869701389.737600.476604.221803.33160HepG2PPIL4
IDH2ENSG00000182054.51290.202501994.49700-0.6284013.7555012.23070HepG2PRPF4
IDH2ENSG00000182054.51749.074001177.402500.570903.197602.33560HepG2PRPF8
IDH2ENSG00000182054.51877.928102442.26930-0.379106.676605.89990HepG2PTBP1
IDH2ENSG00000182054.52991.382802525.271800.244302.113601.58300HepG2PUF60
IDH2ENSG00000182054.51414.060602680.75420-0.9228043.0726041.30610HepG2PUM1
IDH2ENSG00000182054.52273.645202678.75460-0.236602.074301.48850HepG2PUM2
IDH2ENSG00000182054.51502.783802674.48570-0.8316016.8881015.59480HepG2PUS1
IDH2ENSG00000182054.5545.084401505.91690-1.4661015.0845013.56330HepG2RAVER1
IDH2ENSG00000182054.52425.853702835.88380-0.225302.098301.33810HepG2RBM15
IDH2ENSG00000182054.51125.241903368.76420-1.5820080.1262078.10990HepG2RBM22
IDH2ENSG00000182054.51297.549802400.59700-0.8876019.2018017.52820HepG2RBM25
IDH2ENSG00000182054.51553.983101965.83400-0.339202.907601.88890HepG2RBM27
IDH2ENSG00000182054.52185.179102531.42240-0.212202.555401.95940HepG2RECQL
IDH2ENSG00000182054.51530.888302341.97540-0.613408.301607.21780HepG2RPLP0
IDH2ENSG00000182054.51089.235301479.89810-0.442202.333201.46520HepG2RPS10
IDH2ENSG00000182054.51237.201201812.95560-0.551306.320205.14090HepG2RPS2
IDH2ENSG00000182054.5575.660501164.60850-1.016604.949603.93210HepG2RRP9
IDH2ENSG00000182054.52313.458401387.599200.7374024.4528022.79990HepG2SAFB2
IDH2ENSG00000182054.51489.043002231.10470-0.583404.229503.38680HepG2SF3A3
IDH2ENSG00000182054.5941.101901496.08920-0.668808.368207.20280HepG2SF3B1
IDH2ENSG00000182054.51829.046402542.80500-0.4753010.056609.03330HepG2SF3B4
IDH2ENSG00000182054.51816.164701618.188000.166401.863901.31830HepG2SMN1
IDH2ENSG00000182054.52006.201601467.221000.451302.970101.32520HepG2SND1
IDH2ENSG00000182054.51003.695401664.68130-0.729905.421804.31880HepG2SNRNP70
IDH2ENSG00000182054.51473.871503804.88800-1.3682089.0875087.26880HepG2SRFBP1
IDH2ENSG00000182054.52048.000202654.10230-0.374007.090206.41600HepG2SRSF1
IDH2ENSG00000182054.5978.640501609.95340-0.718206.439004.85520HepG2SRSF3
IDH2ENSG00000182054.51559.891502493.41800-0.6767018.2365016.82570HepG2SRSF5
IDH2ENSG00000182054.51435.840202135.90640-0.5730012.8586011.54690HepG2SRSF7
IDH2ENSG00000182054.51614.321402159.22280-0.419608.146707.28950HepG2SRSF9
IDH2ENSG00000182054.55176.707203303.531100.6479024.1858023.00320HepG2SSB
IDH2ENSG00000182054.51544.763702076.35740-0.426703.217601.84190HepG2SSRP1
IDH2ENSG00000182054.52970.904602101.644500.499303.592302.06540HepG2SUGP2
IDH2ENSG00000182054.51979.584902385.51160-0.269102.068501.57080HepG2TAF15
IDH2ENSG00000182054.5602.136701018.82710-0.758703.143402.08510HepG2TFIP11
IDH2ENSG00000182054.52928.101201514.071700.9514026.3649025.11580HepG2TIAL1
IDH2ENSG00000182054.52289.437701527.554200.5837014.3544013.21210HepG2TRIM56
IDH2ENSG00000182054.51051.266702425.07780-1.2059010.582009.33410HepG2U2AF1
IDH2ENSG00000182054.5476.61550897.89510-0.913704.069003.14850HepG2UCHL5
IDH2ENSG00000182054.5918.703101910.30320-1.0561019.1498017.79320HepG2UTP3
IDH2ENSG00000182054.5938.909201481.44370-0.657904.699703.04460HepG2XRCC5
IDH2ENSG00000182054.51389.029301968.25830-0.5028011.4680010.25900HepG2ZC3H8
IDH2ENSG00000182054.51807.106402176.13240-0.268101.853601.38160HepG2ZNF622
IDH2ENSG00000182054.51215.300501886.00290-0.634003.378102.05760K562AARS
IDH2ENSG00000182054.56482.299504072.483500.670507.785606.90200K562AGGF1
IDH2ENSG00000182054.56546.680504475.514000.548605.856504.29840K562AKAP8
IDH2ENSG00000182054.56640.238304237.719300.647805.298404.37910K562AKAP8L
IDH2ENSG00000182054.51258.785802818.90680-1.163104.055303.37160K562AQR
IDH2ENSG00000182054.56324.409204446.606300.508105.744704.37110K562ATP5C1
IDH2ENSG00000182054.51878.158501607.448900.224402.556301.63650K562BCLAF1
IDH2ENSG00000182054.5859.386202510.14710-1.5464028.3633026.48830K562DDX47
IDH2ENSG00000182054.53439.763502649.290500.376604.075302.39860K562DDX6
IDH2ENSG00000182054.5742.612201341.99620-0.853705.178003.90710K562EFTUD2
IDH2ENSG00000182054.53400.145602870.274800.244303.424402.06570K562EIF2S1
IDH2ENSG00000182054.5373.168601141.71810-1.6133018.1383015.70670K562EIF3A
IDH2ENSG00000182054.5927.993401436.35370-0.630202.942701.87280K562EIF3D
IDH2ENSG00000182054.5680.190301243.34220-0.870207.371106.08450K562EIF3G
IDH2ENSG00000182054.51767.079702730.00670-0.627509.255407.75130K562EIF4A3
IDH2ENSG00000182054.52909.180402383.036900.287703.506602.02330K562EWSR1
IDH2ENSG00000182054.51768.339001408.832500.327803.145301.78760K562EXOSC5
IDH2ENSG00000182054.51875.336601104.593800.763508.493106.91510K562FIP1L1
IDH2ENSG00000182054.51271.113201792.69920-0.496002.439901.39380K562FKBP4
IDH2ENSG00000182054.5669.324802839.09730-2.08470125.50780121.91530K562FXR1
IDH2ENSG00000182054.5814.410501581.78980-0.957704.717403.73770K562G3BP2
IDH2ENSG00000182054.51692.732802241.58190-0.405205.106803.58350K562GLRX3
IDH2ENSG00000182054.51441.421001021.749600.496405.258404.17180K562GPKOW
IDH2ENSG00000182054.52128.017803025.26830-0.507607.549205.85220K562HNRNPA1
IDH2ENSG00000182054.54457.194202697.939000.724203.731502.24480K562HNRNPA2B1
IDH2ENSG00000182054.5677.950002062.09980-1.6049014.6165013.33050K562HNRNPC
IDH2ENSG00000182054.5700.44690908.62850-0.375402.165101.34590K562HNRNPM
IDH2ENSG00000182054.52803.359403350.20740-0.257102.973802.04810K562HNRNPU
IDH2ENSG00000182054.52939.668002155.899300.447302.892101.83760K562IGF2BP2
IDH2ENSG00000182054.52776.957802192.262400.341002.703401.52920K562IGF2BP3
IDH2ENSG00000182054.56036.831204496.873900.424804.367303.30020K562KIF1C
IDH2ENSG00000182054.51337.180001998.93310-0.580002.971001.52500K562LARP7
IDH2ENSG00000182054.51497.799302264.33280-0.596204.611103.51970K562MAGOH
IDH2ENSG00000182054.55966.774504304.943800.470904.831703.28900K562MAK16
IDH2ENSG00000182054.51544.930102259.52130-0.548504.081302.94440K562MATR3
IDH2ENSG00000182054.51937.840502356.75570-0.282402.316501.57450K562MTPAP
IDH2ENSG00000182054.52036.708201323.569500.621703.275301.84060K562NONO
IDH2ENSG00000182054.52980.187902618.429100.186603.112902.32530K562NSUN2
IDH2ENSG00000182054.54471.329702360.080800.921805.770004.18610K562PABPN1
IDH2ENSG00000182054.51131.665902014.43400-0.831907.677306.02020K562PCBP2
IDH2ENSG00000182054.52115.977901254.054100.7546011.427609.42080K562PPIG
IDH2ENSG00000182054.54697.781402806.019200.743403.553601.82860K562PPP1R8
IDH2ENSG00000182054.5498.715301305.92990-1.3888010.127808.68920K562PRPF8
IDH2ENSG00000182054.51442.464402200.04820-0.609004.705703.86220K562PTBP1
IDH2ENSG00000182054.51817.333404091.69970-1.170908.416706.98630K562PUF60
IDH2ENSG00000182054.56294.780404201.827800.583003.776603.15630K562PUS1
IDH2ENSG00000182054.56067.303904094.733500.567205.299504.50300K562RBM15
IDH2ENSG00000182054.51409.974302108.80090-0.580803.536802.58040K562RBM22
IDH2ENSG00000182054.5546.441201329.86110-1.283109.372907.85560K562RPS19
IDH2ENSG00000182054.51083.022602056.10970-0.9249012.4441010.21860K562RPS3
IDH2ENSG00000182054.5763.731201224.67660-0.681308.868006.99570K562SAFB
IDH2ENSG00000182054.5879.749901266.22380-0.525405.171503.19920K562SDAD1
IDH2ENSG00000182054.5723.74850971.81740-0.425202.724901.75810K562SF3B1
IDH2ENSG00000182054.51177.250402156.94160-0.873607.926906.73730K562SRSF1
IDH2ENSG00000182054.53015.901802037.466900.565705.875104.24060K562SRSF5
IDH2ENSG00000182054.51707.899201282.500400.413205.330303.45300K562SSB
IDH2ENSG00000182054.5648.419101378.69610-1.0883024.4003022.13110K562SYNCRIP
IDH2ENSG00000182054.52966.018802105.473600.494305.323704.13600K562TIA1
IDH2ENSG00000182054.52841.146502066.916200.458903.182901.99910K562TRA2A
IDH2ENSG00000182054.53893.649903158.844300.301603.475402.04470K562TROVE2
IDH2ENSG00000182054.51756.399901337.860800.392602.429601.48240K562UCHL5
IDH2ENSG00000182054.53147.854202776.386800.181102.300001.64110K562UPF1
IDH2ENSG00000182054.51246.705802470.52160-0.9867041.9164039.41050K562WDR43
IDH2ENSG00000182054.51348.035002145.89570-0.670703.523901.68580K562XRCC6
IDH2ENSG00000182054.54278.688903174.691800.430502.095601.35470K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for IDH2 is not available on ENCORE database.





1 RBPs can affect the splicing of IDH2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSIDH2ENSG00000182054.5chr15-9063159090631754906315909063173490631818906319790.061000.000000.00000longerHepG2RBM22

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for IDH2 is not avaliable on ENCORE database.