G6PD

General Information

Gene Name       : G6PD
Gene ID             : ENSG00000160211.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: G6PD)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878G6PDENSG00000160211.1714.0632.9123.48ENCSR000AEF
HepG2G6PDENSG00000160211.17115.8959.0087.44ENCSR985KAT
K562G6PDENSG00000160211.17187.78149.00168.39ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for G6PD is not avaliable on ENCORE database.



Proteins bound to RNA
  • G6PD RNA is bound by 15 proteins.  







eCLIP assay for G6PD is not avaliable on ENCORE database.





15 proteins are bound to G6PD RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX153759780153759915-3'-UTR,intron-Distal3.1446611.57789K562UPF1
chrX153759709153759805-3'-UTR,intron-Distal3.022048.71433K562METAP2
chrX153760001153760024-3'-UTR,intron-Distal3.346129.81562K562PABPC4
chrX153759979153760071-3'-UTR,intron-Distal3.694726.16969HepG2LARP4
chrX153760062153760134-3'-UTR,intron-Distal,intron-Proximal4.0353112.36003K562PCBP1
chrX153759963153760001-3'-UTR,intron-Distal3.194586.87580K562PABPC4
chrX153760024153760049-3'-UTR,intron-Distal3.7203511.18542K562PABPC4
chrX153760071153760128-3'-UTR,intron-Distal,intron-Proximal3.715295.27408HepG2LARP4
chrX153760134153760185-3'-UTR,intron-Distal,intron-Proximal4.592756.35799K562PCBP1
chrX153760049153760135-3'-UTR,intron-Distal,intron-Proximal4.0505332.06727K562PABPC4
chrX153759788153759883-3'-UTR,intron-Distal4.817316.59389HepG2G3BP1
chrX153759782153759831-3'-UTR,intron-Distal3.404699.54031K562YBX3
chrX153760051153760129-3'-UTR,intron-Distal,intron-Proximal3.735264.45619HepG2UPF1
chrX153759817153759909-3'-UTR,intron-Distal4.646755.41597HepG2UPF1
chrX153759719153759782-3'-UTR,intron-Distal3.2133914.38655K562YBX3
chrX153760018153760123-3'-UTR,intron-Distal,intron-Proximal3.4335015.98962K562IGF2BP2
chrX153759957153760051-3'-UTR,intron-Distal3.291185.69025HepG2UPF1
chrX153774343153774376-5'-UTR,CDS,intron-Distal,intron-Proximal3.098624.59873K562UCHL5
chrX153761793153761827-CDS,intron-Distal4.003953.80193HepG2GRWD1
chrX153764355153764374-CDS,intron-Distal,intron-Proximal4.223179.44646K562YBX3
chrX153774250153774274-CDS,intron-Distal,intron-Proximal3.183584.59873K562UCHL5
chrX153762576153762662-CDS,intron-Distal4.518204.25741HepG2G3BP1
chrX153764176153764223-CDS,intron-Distal4.091703.36483HepG2G3BP1
chrX153762632153762698-CDS,intron-Distal3.942233.86058K562GRWD1
chrX153762640153762711-CDS,intron-Distal4.165255.75613K562ZNF800
chrX153764375153764393-CDS,intron-Distal4.2828218.21319K562YBX3
chrX153764318153764411-CDS,intron-Distal,intron-Proximal4.891224.02817HepG2PRPF8
chrX153764348153764426-CDS,intron-Distal,intron-Proximal3.922563.96535HepG2AQR
chrX153774250153774269-CDS,intron-Distal,intron-Proximal3.5080211.24658K562YBX3
chrX153764174153764225-CDS,intron-Distal3.1921513.46097K562YBX3
chrX153763402153763476-CDS,intron-Distal3.059356.54259K562METAP2
chrX153760819153760832-CDS,intron-Distal4.134624.31428K562YBX3
chrX153764154153764167-CDS,intron-Distal3.369374.31744K562YBX3
chrX153763514153763602-CDS,intron-Distal,intron-Proximal3.663254.70460K562DDX24
chrX153764225153764260-CDS,intron-Distal,intron-Proximal3.8926715.64247K562YBX3
chrX153764108153764167-CDS,intron-Distal,intron-Proximal3.300455.75231K562AQR
chrX153760274153760306-CDS,intron-Distal,intron-Proximal4.216475.37920K562PABPC4
chrX153760265153760305-CDS,intron-Distal,intron-Proximal3.837633.11149HepG2G3BP1
chrX153761649153761679-intron-Distal4.064383.49003K562PRPF8
chrX153762895153762972-intron-Distal4.170853.71567HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for G6PD is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for G6PD is not available on ENCORE database.

  • 136 RBPs can affect the levels of G6PD.  








The Knockdown/knockout RNA-Seq assay for G6PD is not available on ENCORE database.





136 RBPs can affect the gene expression of G6PD :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
G6PDENSG00000160211.113192.622101161.865601.4582092.4486090.26670HepG2ACO1
G6PDENSG00000160211.112181.59510903.078601.2724020.4997019.18880HepG2AKAP1
G6PDENSG00000160211.113565.082901084.654701.7166041.4754038.18180HepG2AKAP8
G6PDENSG00000160211.111621.261101141.302000.506302.930301.96230HepG2BCCIP
G6PDENSG00000160211.11686.69250991.51470-0.530002.970302.03760HepG2BCLAF1
G6PDENSG00000160211.113683.753301538.956001.2591034.5494032.85290HepG2BOP1
G6PDENSG00000160211.11523.21580854.39150-0.707508.507207.26010HepG2CALR
G6PDENSG00000160211.112219.896701628.208200.447102.988901.97430HepG2CCAR1
G6PDENSG00000160211.111730.790501161.384300.5755014.0487012.79120HepG2CKAP4
G6PDENSG00000160211.111711.683601181.269000.535002.070301.41350HepG2CNOT7
G6PDENSG00000160211.11850.048501412.84910-0.733009.145807.96480HepG2CPSF6
G6PDENSG00000160211.11394.68220710.96030-0.8491012.1612010.11140HepG2YBX3
G6PDENSG00000160211.111113.98420704.706000.660506.343404.81290HepG2CSTF2
G6PDENSG00000160211.113232.110601239.437501.3827028.4661026.86040HepG2CELF1
G6PDENSG00000160211.111028.62730711.976900.530706.607304.91360HepG2DDX1
G6PDENSG00000160211.111021.98990658.512200.634007.041606.01060HepG2DDX21
G6PDENSG00000160211.11426.46370644.98010-0.596804.150703.02110HepG2DDX24
G6PDENSG00000160211.111097.11130864.981000.342902.033501.48830HepG2DDX3X
G6PDENSG00000160211.112727.908001984.946900.458605.137003.40610HepG2DDX47
G6PDENSG00000160211.111127.84670640.789400.815505.762103.88840HepG2DDX52
G6PDENSG00000160211.112780.401401122.234601.3088019.9908018.18950HepG2DDX55
G6PDENSG00000160211.112058.96950743.272001.469909.179508.12430HepG2DDX6
G6PDENSG00000160211.11522.67240673.34810-0.365402.369301.46220HepG2DHX30
G6PDENSG00000160211.111702.514001111.531400.6150010.657109.50460HepG2DKC1
G6PDENSG00000160211.11958.91270691.929100.470707.009906.03840HepG2DNAJC2
G6PDENSG00000160211.111171.69240764.287700.616302.865101.92890HepG2EEF2
G6PDENSG00000160211.111697.55740714.291701.2488022.1342020.56480HepG2EIF2S1
G6PDENSG00000160211.111386.715001086.586800.351803.237601.96460HepG2EIF2S2
G6PDENSG00000160211.11980.28920620.286000.660202.814401.90500HepG2EIF3D
G6PDENSG00000160211.111008.42900789.263300.353401.872101.34230HepG2EIF4A3
G6PDENSG00000160211.11653.597201314.76690-1.0083024.8742022.90640HepG2EIF4G1
G6PDENSG00000160211.11768.975701259.43400-0.711808.257606.88370HepG2EIF4G2
G6PDENSG00000160211.111209.011202648.48480-1.1313019.5417018.18610HepG2ETF1
G6PDENSG00000160211.11438.99290933.97410-1.089205.930304.13890HepG2FKBP4
G6PDENSG00000160211.11689.569601415.26330-1.037305.406203.99120HepG2FTO
G6PDENSG00000160211.11924.97410643.682100.523004.764203.74880HepG2FUBP3
G6PDENSG00000160211.112713.25910796.675601.7679047.1343044.70800HepG2FXR1
G6PDENSG00000160211.111996.06690738.853501.4337027.8645025.84510HepG2G3BP1
G6PDENSG00000160211.111139.74980784.622800.538504.583903.42740HepG2G3BP2
G6PDENSG00000160211.111737.160701109.110300.6472014.9334012.97080HepG2HDGF
G6PDENSG00000160211.111889.802801000.200100.917808.669306.16930HepG2HNRNPA0
G6PDENSG00000160211.112035.98020976.571401.0598012.899609.88530HepG2HNRNPAB
G6PDENSG00000160211.111652.752802213.28720-0.421307.672706.55810HepG2HNRNPF
G6PDENSG00000160211.111900.66280748.576201.3442029.7073027.67870HepG2HNRNPK
G6PDENSG00000160211.111790.123001213.763300.5605011.7041010.40270HepG2HNRNPL
G6PDENSG00000160211.111811.834602179.44960-0.266502.446201.76360HepG2IGF2BP1
G6PDENSG00000160211.111951.88520750.964501.3780017.2082015.69920HepG2IGF2BP2
G6PDENSG00000160211.111451.58390705.005501.041802.282401.39620HepG2IGF2BP3
G6PDENSG00000160211.112092.472601126.907500.892708.078105.94310HepG2KHDRBS1
G6PDENSG00000160211.111268.73290755.461600.747906.367104.78370HepG2KHSRP
G6PDENSG00000160211.113798.791101720.271101.1428017.1699015.12700HepG2LARP4
G6PDENSG00000160211.111179.01910693.052500.766504.403502.96410HepG2LARP7
G6PDENSG00000160211.111279.47320796.955300.682906.865605.84650HepG2MAGOH
G6PDENSG00000160211.112146.85320801.360101.4216026.1945024.42950HepG2MATR3
G6PDENSG00000160211.111213.69570649.082500.902806.705505.12990HepG2METAP2
G6PDENSG00000160211.11776.106001558.76890-1.006108.669906.93040HepG2MTPAP
G6PDENSG00000160211.112002.38060820.191401.2876023.0708021.35910HepG2NCBP2
G6PDENSG00000160211.112167.029201118.725400.953804.487702.66690HepG2NKRF
G6PDENSG00000160211.111844.295401321.329100.481004.130903.19820HepG2NOL12
G6PDENSG00000160211.112923.437701030.995201.5035014.8499012.19550HepG2NONO
G6PDENSG00000160211.11834.51490358.258701.219804.125701.85600HepG2NUFIP2
G6PDENSG00000160211.112890.854101080.094801.420202.794701.90270HepG2PABPC1
G6PDENSG00000160211.11444.85300730.22610-0.715004.296603.40950HepG2PABPC4
G6PDENSG00000160211.11815.29530512.987400.668304.070702.57010HepG2PKM
G6PDENSG00000160211.111932.867501059.628300.867103.545801.82010HepG2PNPT1
G6PDENSG00000160211.111254.108001487.31810-0.246102.493601.75490HepG2PRPF4
G6PDENSG00000160211.11454.62560865.18870-0.928305.383704.29510HepG2PRPF8
G6PDENSG00000160211.112330.62030808.749801.5268075.4698073.53700HepG2PTBP1
G6PDENSG00000160211.112782.270401339.065501.0549013.3195012.22400HepG2PUM1
G6PDENSG00000160211.112272.347601338.050200.764005.922904.95440HepG2PUM2
G6PDENSG00000160211.112070.882301183.402000.8072014.8126013.58730HepG2PUS1
G6PDENSG00000160211.111265.84720875.702700.531505.589904.74810HepG2QKI
G6PDENSG00000160211.111278.02620646.324300.983504.253703.38900HepG2RAVER1
G6PDENSG00000160211.111111.61870360.674101.623803.872901.70820HepG2RBM17
G6PDENSG00000160211.111422.24470835.771800.766903.500202.37720HepG2RBM27
G6PDENSG00000160211.111882.806001141.334200.722104.303702.41070HepG2RBM47
G6PDENSG00000160211.111161.65970678.689600.775303.093901.97090HepG2RCC2
G6PDENSG00000160211.112223.45450899.985501.3047054.0556052.38120HepG2NELFE
G6PDENSG00000160211.111138.35620838.350800.441202.294801.72710HepG2RECQL
G6PDENSG00000160211.111839.325302384.34880-0.374402.344601.70750HepG2RPLP0
G6PDENSG00000160211.111204.72270603.709800.996709.003207.96970HepG2RPS19
G6PDENSG00000160211.11560.49290855.79920-0.610603.177902.34350HepG2RRP9
G6PDENSG00000160211.11562.10700693.56310-0.303202.012801.44930HepG2SAFB2
G6PDENSG00000160211.111003.30540348.219401.526606.212704.04220HepG2SF1
G6PDENSG00000160211.112302.311101204.514400.9345010.503309.12700HepG2SF3A3
G6PDENSG00000160211.11558.642301512.84000-1.4373031.5090029.45020HepG2SF3B1
G6PDENSG00000160211.112450.48690841.850301.5413078.1839075.89760HepG2SF3B4
G6PDENSG00000160211.111018.20140338.297601.589606.132003.81410HepG2SFPQ
G6PDENSG00000160211.111821.53930808.828401.1712052.5594050.43200HepG2SMN1
G6PDENSG00000160211.113719.001701683.297701.143502.917102.11280HepG2SNRNP70
G6PDENSG00000160211.111182.876602500.09560-1.0797018.4052017.41530HepG2SRFBP1
G6PDENSG00000160211.111253.52930878.775800.512303.441602.92920HepG2SRSF1
G6PDENSG00000160211.111164.417001627.80500-0.483303.230302.14020HepG2SRSF3
G6PDENSG00000160211.112407.223101245.496200.9505035.0893033.21400HepG2SRSF5
G6PDENSG00000160211.111334.869902174.50380-0.7040018.9527017.42620HepG2SRSF7
G6PDENSG00000160211.111274.43480714.988100.8338016.8850015.72820HepG2SRSF9
G6PDENSG00000160211.111642.184702170.53330-0.402404.779304.14200HepG2SSB
G6PDENSG00000160211.111576.416601033.382100.609202.444101.41910HepG2STIP1
G6PDENSG00000160211.112344.819101416.410900.7271018.9155017.52390HepG2SUCLG1
G6PDENSG00000160211.111517.391401117.015100.441802.277801.65650HepG2SUPV3L1
G6PDENSG00000160211.11395.03040790.06210-1.000006.940306.12180HepG2TAF15
G6PDENSG00000160211.11689.695901489.71080-1.1110019.9619018.34180HepG2TARDBP
G6PDENSG00000160211.111307.15730748.603400.804107.605906.09960HepG2TFIP11
G6PDENSG00000160211.11239.76820756.80990-1.6583036.4151034.97930HepG2TIAL1
G6PDENSG00000160211.111411.60350763.507500.8865023.5505022.10380HepG2TRIM56
G6PDENSG00000160211.11702.106601232.40810-0.8117012.3076010.27080HepG2TUFM
G6PDENSG00000160211.11944.878001237.28440-0.389002.820702.18650HepG2U2AF1
G6PDENSG00000160211.111580.90370659.751201.2607021.5801019.54200HepG2UCHL5
G6PDENSG00000160211.111671.920401068.218500.6462015.4040014.01030HepG2UPF1
G6PDENSG00000160211.112210.873001031.325401.1000012.9297011.77600HepG2UTP3
G6PDENSG00000160211.111242.45330711.218300.804703.332702.16660HepG2XRCC6
G6PDENSG00000160211.111793.944401467.782300.289404.244603.44040HepG2ZC3H8
G6PDENSG00000160211.114985.389503315.259400.5885018.9306017.56810K562AGGF1
G6PDENSG00000160211.111832.943904311.39010-1.2340032.1977030.39260K562AQR
G6PDENSG00000160211.112910.183902394.241700.281402.154401.30550K562BCLAF1
G6PDENSG00000160211.112398.909901816.389400.401205.792304.18030K562CSTF2
G6PDENSG00000160211.114792.212706872.12560-0.5201010.662108.81640K562CELF1
G6PDENSG00000160211.113616.625304356.84290-0.268604.276103.49050K562DDX47
G6PDENSG00000160211.111440.704302292.55290-0.670204.588903.26290K562EIF3A
G6PDENSG00000160211.111408.68150977.472500.527104.388303.39500K562EIF3G
G6PDENSG00000160211.111653.704802400.13220-0.537406.837105.55740K562EIF4A3
G6PDENSG00000160211.114427.095405588.86670-0.336205.850904.50700K562EIF4G2
G6PDENSG00000160211.113079.716302347.496900.391603.094402.19460K562FIP1L1
G6PDENSG00000160211.111407.611602031.21410-0.529105.196903.56590K562FKBP4
G6PDENSG00000160211.112916.842302496.030100.224702.511501.92880K562FXR1
G6PDENSG00000160211.11130.94590713.52210-2.4460014.5980012.67730K562G3BP2
G6PDENSG00000160211.112079.418103766.06340-0.8569026.3176023.54830K562GLRX3
G6PDENSG00000160211.113669.031104989.31700-0.443404.306503.36710K562GRSF1
G6PDENSG00000160211.111686.234302337.72130-0.471306.136305.28160K562HNRNPC
G6PDENSG00000160211.113379.180804514.58990-0.417902.873601.96330K562HNRNPU
G6PDENSG00000160211.113019.963101648.471900.873302.420001.47930K562IGF2BP2
G6PDENSG00000160211.112596.378701676.078100.631302.717301.53810K562IGF2BP3
G6PDENSG00000160211.11878.206401503.90950-0.776104.830503.55580K562KRR1
G6PDENSG00000160211.112673.860802085.589500.358402.871401.31610K562LSM11
G6PDENSG00000160211.114244.584403504.442100.276302.246001.30980K562MAK16
G6PDENSG00000160211.113134.192103959.53710-0.337206.819305.59730K562MTPAP
G6PDENSG00000160211.114857.583104399.331200.142902.415801.71380K562NSUN2
G6PDENSG00000160211.113726.416302665.234200.483403.994702.98510K562PPIG
G6PDENSG00000160211.111337.635502102.88040-0.652702.033501.38620K562PRPF8
G6PDENSG00000160211.112742.448601681.789800.705406.920105.90580K562PTBP1
G6PDENSG00000160211.113869.571906097.84960-0.6561011.152009.50330K562PUF60
G6PDENSG00000160211.115254.070506486.20290-0.303904.003902.69860K562PUM1
G6PDENSG00000160211.115253.648303421.221800.618702.638902.10500K562PUS1
G6PDENSG00000160211.113958.083303333.380500.247702.876902.27370K562RBM15
G6PDENSG00000160211.112505.538201571.830600.672603.929402.17760K562RBM34
G6PDENSG00000160211.113033.195301913.087500.6648012.6712010.53950K562RCC2
G6PDENSG00000160211.112673.771703413.55980-0.352403.344901.73370K562SDAD1
G6PDENSG00000160211.111106.473301674.99180-0.598204.107602.90670K562SF3B1
G6PDENSG00000160211.112240.862301813.490700.305202.517901.55120K562SRFBP1
G6PDENSG00000160211.113392.554504447.58200-0.3906010.819009.11110K562SRPK2
G6PDENSG00000160211.112292.984701648.892800.475602.445701.77390K562SRSF1
G6PDENSG00000160211.112436.547701557.695600.645303.278802.11750K562SRSF5
G6PDENSG00000160211.113447.761804217.34540-0.290703.426801.72410K562SRSF9
G6PDENSG00000160211.11320.01910700.34920-1.129904.007202.11490K562TAF15
G6PDENSG00000160211.112708.102601609.464300.750606.011104.73360K562TIA1
G6PDENSG00000160211.11846.917802016.06230-1.2512024.0663021.13140K562TIAL1
G6PDENSG00000160211.112766.049601580.271200.807604.122902.74630K562TRA2A
G6PDENSG00000160211.112745.937302142.507400.357903.450402.37300K562TRIM56
G6PDENSG00000160211.11316.85460690.87170-1.124604.284202.86040K562U2AF1
G6PDENSG00000160211.11242.15440713.76970-1.5595011.6990010.03300K562U2AF2
G6PDENSG00000160211.112499.119604150.69220-0.7319030.8588028.58370K562WDR43
G6PDENSG00000160211.113956.341505108.64330-0.368804.431702.78890K562WRN
G6PDENSG00000160211.113516.306404856.70750-0.465906.069304.70850K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for G6PD is not available on ENCORE database.





2 RBPs can affect the splicing of G6PD :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSG6PDENSG00000160211.11chrX-1537602971537605141537602971537604951537606001537606770.051000.000000.00000longerK562AQR
A3SSG6PDENSG00000160211.11chrX-1537625521537627281537625521537627141537633821537636000.190000.012070.06211longerK562AQR
A5SSG6PDENSG00000160211.11chrX-153764151153764260153764168153764260153763382153763600-0.056000.000370.06150shorterK562TARDBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for G6PD is not avaliable on ENCORE database.