ARL2

General Information

Gene Name       : ARL2
Gene ID             : ENSG00000213465.7
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: ARL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ARL2ENSG00000213465.715.4933.4724.48ENCSR000AEF
HepG2ARL2ENSG00000213465.790.5137.1563.83ENCSR985KAT
K562ARL2ENSG00000213465.799.8562.0280.94ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ARL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ARL2 RNA is bound by 15 proteins.  







eCLIP assay for ARL2 is not avaliable on ENCORE database.





15 proteins are bound to ARL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116478943564789546+3'-UTR,intron-Distal,intron-Proximal3.206267.69995K562IGF2BP2
chr116478932364789378+3'-UTR,CDS,intron-Distal,intron-Proximal3.207583.67576K562IGF2BP2
chr116478936564789424+3'-UTR,intron-Distal,intron-Proximal3.841723.35877HepG2UPF1
chr116478956264789627+3'-UTR,intron-Distal5.3129816.66765K562PABPC4
chr116478941164789615+3'-UTR,intron-Distal,intron-Proximal4.0759615.47176HepG2LARP4
chr116478937464789435+3'-UTR,intron-Distal,intron-Proximal3.795736.00535K562METAP2
chr116478928764789411+3'-UTR,CDS,intron-Distal,intron-Proximal5.1496515.30399HepG2LARP4
chr116478953864789621+3'-UTR,intron-Distal3.527225.11124K562DDX6
chr116478928464789339+3'-UTR,CDS,intron-Distal4.4248912.35914K562PABPC4
chr116478949864789551+3'-UTR,intron-Distal4.8937313.44822K562PABPC4
chr116478941864789467+3'-UTR,intron-Distal,intron-Proximal4.026167.65013K562PABPC4
chr116478928564789362+3'-UTR,CDS,intron-Distal,intron-Proximal3.5447311.48996K562DDX55
chr116478942464789615+3'-UTR,intron-Distal,intron-Proximal5.7827714.82289HepG2UPF1
chr116478922564789374+3'-UTR,CDS,intron-Distal,intron-Proximal5.299296.54919HepG2RPS3
chr116478943164789620+3'-UTR,intron-Distal,intron-Proximal3.102214.88668HepG2AKAP1
chr116478936264789413+3'-UTR,intron-Distal,intron-Proximal4.076543.94601K562PCBP1
chr116478933964789402+3'-UTR,intron-Distal,intron-Proximal4.1518611.02630K562PABPC4
chr116478943364789527+3'-UTR,intron-Distal,intron-Proximal3.004646.31483K562DDX55
chr116478936264789433+3'-UTR,intron-Distal,intron-Proximal3.128498.77682K562DDX55
chr116478166064781745+5'-UTR,CDS,intron-Proximal4.4635312.05885K562PABPC4
chr116478161464781706+5'-UTR,CDS3.736446.97927K562DDX3X
chr116478604264786121+CDS,intron-Proximal3.114875.48666K562METAP2
chr116478791564787964+CDS,intron-Distal3.383979.93836K562YBX3
chr116478604164786054+CDS,intron-Proximal3.594618.43159K562YBX3
chr116478583664785901+CDS3.761837.27995K562PABPC4
chr116478584664785887+CDS3.0980013.04052K562YBX3
chr116478604264786106+CDS,intron-Proximal3.567926.09767K562UCHL5
chr116478604064786183+CDS,intron-Proximal4.102516.84754HepG2GRWD1
chr116478612164786203+CDS4.004824.75480HepG2RPS3
chr116478592164785947+CDS,intron-Proximal3.245826.77366K562YBX3
chr116478608064786178+CDS3.765275.19325HepG2LARP4
chr116478612164786203+CDS4.526214.49458K562METAP2
chr116478587264785946+CDS4.180725.04143K562GRWD1
chr116478620464786254+CDS,intron-Proximal4.964545.17615K562AQR
chr116478583464785851+CDS,intron-Proximal3.997744.92682K562DDX55
chr116478588764785921+CDS3.8499016.21789K562YBX3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ARL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ARL2 is not available on ENCORE database.

  • 90 RBPs can affect the levels of ARL2.  








The Knockdown/knockout RNA-Seq assay for ARL2 is not available on ENCORE database.





90 RBPs can affect the gene expression of ARL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ARL2ENSG00000213465.31343.71900892.096700.590904.679803.48220HepG2ABCF1
ARL2ENSG00000213465.3541.14850353.367300.614802.891201.87270HepG2ADAR
ARL2ENSG00000213465.31335.129901039.730500.360702.031801.56810HepG2AKAP1
ARL2ENSG00000213465.3947.69330584.451000.697206.042004.53380HepG2AKAP8
ARL2ENSG00000213465.3845.95360991.65530-0.229301.954601.36000HepG2AUH
ARL2ENSG00000213465.3347.02960479.77650-0.467303.075702.26530HepG2CALR
ARL2ENSG00000213465.3183.01900453.38190-1.308702.703901.94840HepG2CNOT7
ARL2ENSG00000213465.3609.92960372.006900.713205.608404.66180HepG2CPSF6
ARL2ENSG00000213465.3470.41660362.373800.376402.492101.52900HepG2YBX3
ARL2ENSG00000213465.3850.98510720.518300.240002.096001.43810HepG2DAZAP1
ARL2ENSG00000213465.3610.53030362.879100.750504.199802.79430HepG2DDX1
ARL2ENSG00000213465.3311.37780528.30590-0.762703.599502.54910HepG2DDX24
ARL2ENSG00000213465.3485.91380355.823500.449401.969301.36500HepG2DNAJC21
ARL2ENSG00000213465.3606.83980352.682100.7828012.0197010.76370HepG2DNAJC2
ARL2ENSG00000213465.3783.15250569.997300.458202.916201.97180HepG2EEF2
ARL2ENSG00000213465.3499.28200710.85220-0.509705.194304.10530HepG2EIF4G1
ARL2ENSG00000213465.3738.809901138.60240-0.6240010.806409.74450HepG2ETF1
ARL2ENSG00000213465.3542.27930413.599200.390702.603401.47210HepG2FAM120A
ARL2ENSG00000213465.3563.35800888.55450-0.657404.662803.65860HepG2FUBP3
ARL2ENSG00000213465.3497.22290662.18630-0.413303.496902.46380HepG2HNRNPA2B1
ARL2ENSG00000213465.3759.94690399.579900.927302.473201.81460HepG2HNRNPC
ARL2ENSG00000213465.3501.59580861.92770-0.781005.538704.57680HepG2HNRNPK
ARL2ENSG00000213465.3866.74780656.331100.401104.746003.88030HepG2HNRNPL
ARL2ENSG00000213465.3793.06650396.938100.9984015.1746013.84600HepG2HNRNPU
ARL2ENSG00000213465.3621.55120405.459000.616208.492107.27670HepG2ILF2
ARL2ENSG00000213465.3541.01680922.63650-0.770103.231602.55410HepG2MATR3
ARL2ENSG00000213465.3493.89220728.70010-0.561104.322803.32390HepG2MSI2
ARL2ENSG00000213465.31033.60140714.465500.532606.566505.39640HepG2NOL12
ARL2ENSG00000213465.3543.08320840.68280-0.630404.881203.93280HepG2PABPC4
ARL2ENSG00000213465.3753.79610970.96080-0.365203.863703.17170HepG2PCBP1
ARL2ENSG00000213465.3585.43540354.037000.725508.582307.33220HepG2PPIL4
ARL2ENSG00000213465.31186.70870682.025200.7990011.6675010.55910HepG2PUF60
ARL2ENSG00000213465.31031.39370724.006100.510408.633407.70880HepG2PUM1
ARL2ENSG00000213465.3578.34930723.47330-0.323002.182301.58330HepG2PUM2
ARL2ENSG00000213465.3883.02910741.923800.251102.189101.62580HepG2PUS1
ARL2ENSG00000213465.3561.91110971.10490-0.789309.769608.55900HepG2RBM25
ARL2ENSG00000213465.3659.11070444.910900.566902.897101.81060HepG2RCC2
ARL2ENSG00000213465.3892.753601099.54400-0.300602.733802.19510HepG2NELFE
ARL2ENSG00000213465.3767.58910353.490801.1186021.3548019.80620HepG2SAFB2
ARL2ENSG00000213465.3489.910901028.60470-1.0701023.8659022.42120HepG2SF3B4
ARL2ENSG00000213465.3553.53500412.229700.425103.858703.11990HepG2SMN1
ARL2ENSG00000213465.3846.570601074.83610-0.344404.004803.43450HepG2SRFBP1
ARL2ENSG00000213465.3566.757301073.65930-0.9217019.7276018.70690HepG2SRSF1
ARL2ENSG00000213465.3810.28490673.408000.266802.167801.60640HepG2SRSF5
ARL2ENSG00000213465.3288.27980873.49520-1.5993045.7827044.08320HepG2SRSF9
ARL2ENSG00000213465.3916.53490765.844000.259002.381001.79580HepG2SUCLG1
ARL2ENSG00000213465.3618.34070965.09900-0.642308.915408.00190HepG2TAF15
ARL2ENSG00000213465.3565.85230886.73920-0.648103.306002.39680HepG2TIA1
ARL2ENSG00000213465.3779.15540389.147401.0015012.1257011.06760HepG2TRIM56
ARL2ENSG00000213465.3442.83990770.35220-0.798708.379007.28500HepG2U2AF1
ARL2ENSG00000213465.3545.14660800.96710-0.555107.474206.41940HepG2UPF1
ARL2ENSG00000213465.3758.88330460.772800.719701.967601.34850HepG2XRN2
ARL2ENSG00000213465.32618.673501833.493600.5141012.0168010.92630K562AGGF1
ARL2ENSG00000213465.32603.583502014.811200.369803.876802.67240K562AKAP8
ARL2ENSG00000213465.32289.556701907.852600.263002.116401.54170K562AKAP8L
ARL2ENSG00000213465.32482.171101922.531700.368503.344001.97550K562APOBEC3C
ARL2ENSG00000213465.3904.417601506.95660-0.736608.898507.94340K562AQR
ARL2ENSG00000213465.32489.028902001.833300.314204.173703.03100K562ATP5C1
ARL2ENSG00000213465.3534.73070700.31200-0.389202.385901.58180K562BOP1
ARL2ENSG00000213465.3488.522601326.10620-1.4407015.2357012.82610K562CNOT7
ARL2ENSG00000213465.31289.39090976.677300.400603.878102.61570K562DDX3X
ARL2ENSG00000213465.31259.74540990.199700.347203.592902.04900K562DDX6
ARL2ENSG00000213465.32368.590702052.864500.206302.201201.43060K562DKC1
ARL2ENSG00000213465.31307.959101072.701500.286002.998001.73100K562EIF2S1
ARL2ENSG00000213465.31047.727201235.86190-0.238302.066201.42880K562EIF2S2
ARL2ENSG00000213465.3613.65950992.36560-0.693403.841702.63320K562EIF3A
ARL2ENSG00000213465.31252.88220890.640700.492206.318904.19980K562EWSR1
ARL2ENSG00000213465.31809.51410971.941400.8966015.5453013.37000K562FIP1L1
ARL2ENSG00000213465.3457.43290642.22450-0.489503.097302.12440K562FTO
ARL2ENSG00000213465.3864.662401061.11670-0.295402.737602.13510K562FXR1
ARL2ENSG00000213465.3205.04290569.82270-1.474605.735404.63410K562G3BP2
ARL2ENSG00000213465.32156.473401646.832400.388903.980203.07630K562GRSF1
ARL2ENSG00000213465.3719.594601293.75360-0.846306.321705.45490K562HNRNPC
ARL2ENSG00000213465.31922.595701317.619100.545006.273905.08650K562HSPD1
ARL2ENSG00000213465.31202.58710734.739300.710702.357001.43150K562IGF2BP2
ARL2ENSG00000213465.31074.16720747.094100.523802.806701.60440K562IGF2BP3
ARL2ENSG00000213465.3408.36590607.07380-0.572003.300602.27110K562KRR1
ARL2ENSG00000213465.31166.84090764.289100.610303.842002.25620K562NONO
ARL2ENSG00000213465.31382.621601700.26920-0.298404.789503.84510K562NSUN2
ARL2ENSG00000213465.31728.683601010.968100.773803.723302.52610K562PABPN1
ARL2ENSG00000213465.3396.32670686.42700-0.792405.077603.74460K562PCBP2
ARL2ENSG00000213465.3891.962701377.66370-0.627206.055904.81970K562PCBP3
ARL2ENSG00000213465.3787.564801056.72900-0.424104.189903.20180K562POLR2G
ARL2ENSG00000213465.31568.355301103.476400.507103.344602.42710K562PPIG
ARL2ENSG00000213465.32131.804401201.551900.827103.765301.97200K562PPP1R8
ARL2ENSG00000213465.31135.89530749.701500.599304.925904.06370K562PTBP1
ARL2ENSG00000213465.32136.571902477.49980-0.213602.525901.60700K562PUM2
ARL2ENSG00000213465.32957.663001891.927800.644507.229006.39860K562PUS1
ARL2ENSG00000213465.32324.595201843.513400.334404.363903.63710K562RBM15
ARL2ENSG00000213465.31072.531701677.83000-0.6456012.9964011.33450K562SF3A3
ARL2ENSG00000213465.3394.91290676.16940-0.775906.380804.86920K562SF3B1
ARL2ENSG00000213465.3408.21600591.89040-0.536002.340201.55530K562SF3B4
ARL2ENSG00000213465.31836.065101126.545300.704602.787101.47970K562SFPQ
ARL2ENSG00000213465.31083.425001718.98190-0.6660017.1462015.09980K562SRPK2
ARL2ENSG00000213465.31068.67110694.335200.622004.408403.03150K562SRSF5
ARL2ENSG00000213465.31186.98160717.468100.726208.212206.69120K562TIA1
ARL2ENSG00000213465.3995.77170704.382700.499402.501601.47480K562TRA2A
ARL2ENSG00000213465.31331.782901802.83680-0.436907.554106.43950K562UPF1
ARL2ENSG00000213465.31067.567201604.20640-0.5875013.0532011.37680K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ARL2 is not available on ENCORE database.





5 RBPs can affect the splicing of ARL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIARL2ENSG00000213465.3chr11+647891926478965664789192647893606478944264789656-0.093000.000120.01405excludedHepG2HNRNPL
RIARL2ENSG00000213465.3chr11+6478919264789656647891926478936064789442647896560.087000.000110.00139includedHepG2U2AF2
RIARL2ENSG00000213465.3chr11+647891926478965664789192647893606478944264789656-0.159000.003130.06353excludedHepG2FTO
RIARL2ENSG00000213465.3chr11+6478919264789656647891926478936064789442647896560.079000.001420.01663includedHepG2RBM22
RIARL2ENSG00000213465.3chr11+647891926478965664789192647893606478944264789656-0.053000.000350.00256excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ARL2 is not avaliable on ENCORE database.