CLPP

General Information

Gene Name       : CLPP
Gene ID             : ENSG00000125656.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CLPP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CLPPENSG00000125656.94.6425.5715.11ENCSR000AEF
HepG2CLPPENSG00000125656.977.3619.3248.34ENCSR985KAT
K562CLPPENSG00000125656.978.5828.3853.48ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CLPP is not avaliable on ENCORE database.



Proteins bound to RNA
  • CLPP RNA is bound by 9 proteins.  







eCLIP assay for CLPP is not avaliable on ENCORE database.





9 proteins are bound to CLPP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1963688146368881+3'-UTR4.040375.19325HepG2LARP4
chr1963688336368857+3'-UTR6.6324629.96773K562PABPC4
chr1963685876368604+3'-UTR,CDS3.010013.29348K562YBX3
chr1963686986368786+3'-UTR,CDS4.601224.89487HepG2LARP4
chr1963686596368714+3'-UTR,CDS3.963693.25521K562LIN28B
chr1963688576368892+3'-UTR5.7784117.53659K562PABPC4
chr1963618776361939+5'-UTR,CDS,intron-Proximal5.508669.01147K562METAP2
chr1963618586361907+5'-UTR,CDS,intron-Proximal6.019607.49422HepG2DDX3X
chr1963618996361944+5'-UTR,CDS3.221127.42778K562YBX3
chr1963618796361885+5'-UTR,CDS,intron-Proximal3.362285.56979K562YBX3
chr1963618856361899+5'-UTR,CDS3.592986.82132K562YBX3
chr1963644656364490+CDS,intron-Distal3.210283.68829K562YBX3
chr1963616586361721+CDS4.0132111.04556K562YBX3
chr1963646086364641+CDS,intron-Distal3.919557.46470K562YBX3
chr1963624596362472+CDS3.849043.65750K562YBX3
chr1963645116364583+CDS,intron-Distal4.1683714.92488K562YBX3
chr1963624726362538+CDS,intron-Proximal6.0242920.03354K562YBX3
chr1963662656366314+CDS,intron-Proximal4.045443.66349K562LIN28B
chr1963646416364650+CDS,intron-Distal4.373945.20509K562YBX3
chr1963616026361724+CDS4.406604.17587HepG2DDX3X
chr1963662856366300+CDS3.839326.36657K562YBX3
chr1963616086361703+CDS4.030614.46401K562DDX3X
chr1963622226362322+intron-Distal5.084466.27056HepG2DDX59
chr1963622006362336+intron-Distal6.7967529.40935HepG2PCBP2
chr1963623496362392+intron-Distal,intron-Proximal3.466953.67675HepG2DDX59
chr1963620446362134+intron-Distal,intron-Proximal5.6876311.50340HepG2PCBP2
chr1963622236362310+intron-Distal4.608515.86125HepG2HNRNPK
chr1963621346362196+intron-Distal4.524563.78681HepG2PCBP2
chr1963620376362135+intron-Distal,intron-Proximal3.324573.37567HepG2HNRNPK
chr1963623996362443+intron-Proximal4.598473.97933HepG2DDX59
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CLPP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CLPP is not available on ENCORE database.

  • 88 RBPs can affect the levels of CLPP.  








The Knockdown/knockout RNA-Seq assay for CLPP is not available on ENCORE database.





88 RBPs can affect the gene expression of CLPP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CLPPENSG00000125656.4548.86340431.621300.346602.342101.77500HepG2ACO1
CLPPENSG00000125656.4887.31650560.051300.663802.818602.28190HepG2AKAP1
CLPPENSG00000125656.4344.72330216.503600.670902.460801.74360HepG2CNOT7
CLPPENSG00000125656.4243.11050171.557800.502802.484101.52280HepG2YBX3
CLPPENSG00000125656.4492.91390336.442400.550904.617203.82480HepG2CELF1
CLPPENSG00000125656.4457.60550361.795900.338802.162601.49480HepG2DAZAP1
CLPPENSG00000125656.4141.37850208.50750-0.560502.265501.44860HepG2DDX24
CLPPENSG00000125656.4352.37400211.202600.738403.169801.71810HepG2DDX52
CLPPENSG00000125656.4322.86830166.965900.951309.846708.70570HepG2DNAJC2
CLPPENSG00000125656.4330.80200182.818200.855505.714703.99460HepG2FAM120A
CLPPENSG00000125656.4280.02530440.38450-0.653204.931403.89610HepG2FUBP3
CLPPENSG00000125656.4323.15010179.055500.851703.818502.16070HepG2HNRNPAB
CLPPENSG00000125656.4534.78980329.579800.698208.181107.07770HepG2HNRNPL
CLPPENSG00000125656.4284.51770187.926400.598303.101102.46170HepG2HNRNPU
CLPPENSG00000125656.4283.06500191.961200.560203.775502.93210HepG2ILF2
CLPPENSG00000125656.4748.23050497.013900.590102.965602.31530HepG2MATR3
CLPPENSG00000125656.4312.31150143.355801.123303.351301.75990HepG2NOLC1
CLPPENSG00000125656.4348.01960542.88130-0.641504.680203.71650HepG2NSUN2
CLPPENSG00000125656.4304.19730418.16010-0.459003.212502.56780HepG2PCBP1
CLPPENSG00000125656.4273.10050169.086700.691603.994402.51040HepG2PKM
CLPPENSG00000125656.4294.85750167.615900.814805.084304.11380HepG2PPIL4
CLPPENSG00000125656.4254.42720411.64270-0.694104.025303.11040HepG2PRPF4
CLPPENSG00000125656.4146.48540206.87250-0.498002.044801.34610HepG2PRPF8
CLPPENSG00000125656.4465.50970342.451700.442802.551601.97640HepG2PUF60
CLPPENSG00000125656.4519.46290363.515300.514904.864704.12360HepG2PUM1
CLPPENSG00000125656.4334.88830439.64340-0.392702.835902.21480HepG2PUS1
CLPPENSG00000125656.4293.83790198.986800.562202.797102.17900HepG2RPS19
CLPPENSG00000125656.4333.20970223.714500.574702.792101.71350HepG2RPS5
CLPPENSG00000125656.4129.03490204.62580-0.665202.303901.57950HepG2RRP9
CLPPENSG00000125656.4338.85930167.358901.017605.793204.91460HepG2SAFB2
CLPPENSG00000125656.4826.50340608.084000.442702.549801.90260HepG2SF3A3
CLPPENSG00000125656.4270.58850442.98130-0.711106.444705.60390HepG2SF3B4
CLPPENSG00000125656.4448.49060328.332500.449803.393002.62920HepG2SLBP
CLPPENSG00000125656.4275.05580195.172200.494902.829202.17910HepG2SMN1
CLPPENSG00000125656.4385.40030674.26780-0.807005.070904.00170HepG2SNRNP70
CLPPENSG00000125656.4295.47590462.38860-0.646105.529404.91880HepG2SRSF1
CLPPENSG00000125656.4476.52370338.106400.495003.866803.14820HepG2SRSF5
CLPPENSG00000125656.4223.45480376.18820-0.751506.998406.19270HepG2SRSF9
CLPPENSG00000125656.4371.75250500.73920-0.429703.471602.91160HepG2SSB
CLPPENSG00000125656.4347.86460189.491400.876304.628203.16810HepG2STIP1
CLPPENSG00000125656.4504.81500384.532700.392502.915802.28090HepG2SUCLG1
CLPPENSG00000125656.4155.55720415.64650-1.4179018.3347017.07400HepG2TAF15
CLPPENSG00000125656.4245.54040182.619000.427001.775601.35670HepG2TIAL1
CLPPENSG00000125656.4437.78190184.237101.2485018.2655016.98420HepG2TRIM56
CLPPENSG00000125656.4540.53980354.092900.610203.538902.58730HepG2UBE2L3
CLPPENSG00000125656.4713.79290520.651500.455104.821404.06670HepG2UTP3
CLPPENSG00000125656.4786.43860593.102200.407004.767104.09890HepG2ZNF622
CLPPENSG00000125656.41432.371401028.114400.478307.815806.93080K562AGGF1
CLPPENSG00000125656.41342.914901122.508400.258502.426201.57500K562ATP5C1
CLPPENSG00000125656.4489.78970376.524000.379302.440401.54120K562BCLAF1
CLPPENSG00000125656.4487.96740693.08900-0.506303.622602.62480K562BOP1
CLPPENSG00000125656.4806.19610468.424100.783208.839906.65480K562CCAR1
CLPPENSG00000125656.4577.19040736.95020-0.352502.530601.77950K562CPSF6
CLPPENSG00000125656.4400.57750285.649700.487702.266101.32880K562CSTF2
CLPPENSG00000125656.4943.004601347.20140-0.514606.699905.19940K562CELF1
CLPPENSG00000125656.41490.764301151.126300.372904.840903.63030K562DKC1
CLPPENSG00000125656.4260.08590176.698600.557602.942302.12240K562EIF3G
CLPPENSG00000125656.4615.36240486.569500.338702.409701.35360K562EIF4B
CLPPENSG00000125656.4867.136501095.39920-0.337103.801202.70330K562EIF4G2
CLPPENSG00000125656.4513.65360749.83380-0.545804.438203.35300K562FMR1
CLPPENSG00000125656.4402.09070635.55370-0.660505.231303.93170K562FTO
CLPPENSG00000125656.426.04700148.92010-2.515306.939105.70660K562G3BP2
CLPPENSG00000125656.4831.43810630.443200.399102.326801.47720K562HNRNPM
CLPPENSG00000125656.4563.02510301.785400.899602.759401.73390K562IGF2BP2
CLPPENSG00000125656.4426.94890306.858900.476403.061101.79200K562IGF2BP3
CLPPENSG00000125656.4475.68350316.922800.585804.576503.48740K562MAGOH
CLPPENSG00000125656.41347.544201086.790500.310202.491001.48870K562MAK16
CLPPENSG00000125656.4484.64190316.243100.615804.814303.56200K562MATR3
CLPPENSG00000125656.41637.699801271.826900.364703.939202.82360K562MBNL1
CLPPENSG00000125656.4883.923301167.53350-0.401502.714301.59770K562MSI2
CLPPENSG00000125656.4885.526001121.13900-0.340403.812502.87670K562MTPAP
CLPPENSG00000125656.41040.139401245.67830-0.260203.148002.35610K562NSUN2
CLPPENSG00000125656.41261.64360870.106500.535902.421301.65690K562PPIG
CLPPENSG00000125656.4508.08880307.928500.722406.789705.78510K562PTBP1
CLPPENSG00000125656.4885.693101271.50150-0.521707.128005.35610K562PUM1
CLPPENSG00000125656.4818.58480499.793900.711704.290701.87510K562RBFOX2
CLPPENSG00000125656.41312.908101033.732900.344803.674503.00500K562RBM15
CLPPENSG00000125656.4407.79990287.801000.502702.818401.42750K562RBM34
CLPPENSG00000125656.4557.05540431.644000.367902.232001.34540K562RCC2
CLPPENSG00000125656.4429.48960279.726600.618502.269001.37290K562RPS3
CLPPENSG00000125656.4845.130701229.17830-0.540408.198906.85340K562SF3A3
CLPPENSG00000125656.4595.12320409.165600.540403.963502.66660K562SRFBP1
CLPPENSG00000125656.4988.809101259.32070-0.348904.220503.08980K562SRPK2
CLPPENSG00000125656.4514.76570301.899700.769707.219506.08680K562SRSF1
CLPPENSG00000125656.4512.69690269.947600.925308.669006.66720K562SRSF4
CLPPENSG00000125656.4460.70430285.188700.691802.892301.81540K562SRSF5
CLPPENSG00000125656.4592.490701005.83660-0.763505.660203.67490K562SSRP1
CLPPENSG00000125656.4639.66140920.01760-0.524403.501002.06220K562STAU1
CLPPENSG00000125656.4513.29430305.483700.748606.368005.25390K562TARDBP
CLPPENSG00000125656.4541.46220294.688900.877608.918607.33290K562TIA1
CLPPENSG00000125656.4483.10870289.315900.739602.781101.68590K562TRA2A
CLPPENSG00000125656.480.15880148.89380-0.893402.340601.60290K562U2AF2
CLPPENSG00000125656.4996.302401347.72520-0.435903.482201.89170K562UBE2L3
CLPPENSG00000125656.4982.100501320.81980-0.427506.325805.29140K562UPF1
CLPPENSG00000125656.4842.594201130.18280-0.423604.074103.00430K562WDR3
CLPPENSG00000125656.4845.943101175.26590-0.474405.314604.17870K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CLPP is not available on ENCORE database.





10 RBPs can affect the splicing of CLPP :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECLPPENSG00000125656.4chr19+6364462636464263624566362553636626863663740.106000.000130.03708includedK562SBDS
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.087000.000100.00200includedHepG2SF3A3
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.167000.009430.08457includedHepG2PRPF8
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.088000.001080.07103includedHepG2EFTUD2
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.069000.001110.01729includedHepG2PCBP1
RICLPPENSG00000125656.4chr19+636187963625536361879636195163624566362553-0.061000.000000.00045excludedK562AARS
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.061000.006890.05947includedHepG2U2AF1
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.056000.004870.06694includedHepG2FUBP3
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.089000.000000.00005includedHepG2RBM22
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.074000.004670.04390includedK562EFTUD2
RICLPPENSG00000125656.4chr19+6361879636255363618796361951636245663625530.149000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CLPP is not avaliable on ENCORE database.