EGLN2

General Information

Gene Name       : EGLN2
Gene ID             : ENSG00000269858.5
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EGLN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EGLN2ENSG00000269858.512.8133.7823.30ENCSR000AEF
HepG2EGLN2ENSG00000269858.533.0618.7825.92ENCSR985KAT
K562EGLN2ENSG00000269858.556.9944.1950.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EGLN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EGLN2 RNA is bound by 22 proteins.  







eCLIP assay for EGLN2 is not avaliable on ENCORE database.





22 proteins are bound to EGLN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194131396941314047+3'-UTR,intron-Distal,intron-Proximal3.017533.44337K562METAP2
chr194130623141306295+3'-UTR,5'-UTR,intron-Proximal3.162934.05586HepG2U2AF2
chr194131408541314157+3'-UTR,intron-Distal3.221503.76433K562DDX6
chr194131375941313880+3'-UTR,CDS,intron-Distal,intron-Proximal4.033498.84200K562PABPC4
chr194131406341314165+3'-UTR,intron-Distal,intron-Proximal5.422398.05720K562UPF1
chr194131406841314169+3'-UTR,intron-Distal4.472433.87357K562EWSR1
chr194131366341313727+3'-UTR,CDS,intron-Distal,intron-Proximal4.159485.68247K562SF3B4
chr194131354841313700+3'-UTR,intron-Distal,intron-Proximal5.233589.72234K562HNRNPK
chr194130641641306475+3'-UTR,5'-UTR3.252114.14880HepG2CSTF2T
chr194131356941313666+3'-UTR,intron-Distal,intron-Proximal4.203584.10192HepG2HNRNPK
chr194131423541314298+3'-UTR,intron-Distal4.841665.94928K562UPF1
chr194130623541306282+3'-UTR,5'-UTR,intron-Proximal3.615254.35148K562U2AF1
chr194131395941314003+3'-UTR,intron-Distal,intron-Proximal3.990023.51664K562RBM15
chr194130588941305951+5'-UTR,intron-Distal,intron-Proximal5.102677.38423HepG2PCBP2
chr194130537841305448+5'-UTR,intron-Distal3.821255.39685HepG2CSTF2T
chr194130540141305457+5'-UTR,intron-Distal5.175208.31268K562CSTF2T
chr194130536841305454+5'-UTR,intron-Distal4.287956.85082HepG2FAM120A
chr194130598641306053+5'-UTR,intron-Distal3.891333.34601K562HNRNPK
chr194130538841305446+5'-UTR,intron-Distal3.184883.18246K562PRPF8
chr194130540041305459+5'-UTR,intron-Distal4.130234.85687K562DROSHA
chr194130710041307171+3'-UTR,CDS3.122805.47824K562CSTF2T
chr194130675441306805+3'-UTR,CDS4.318704.32860K562METAP2
chr194130731841307342+3'-UTR,CDS,intron-Proximal5.167366.44303K562AQR
chr194130692341306975+3'-UTR,CDS3.335213.80158K562NONO
chr194130721841307321+3'-UTR,CDS,intron-Proximal3.440903.09251K562METAP2
chr194131298841313067+3'-UTR,CDS,intron-Distal,intron-Proximal3.377093.64784K562EWSR1
chr194130689841306978+3'-UTR,CDS4.1369712.33599K562CSTF2T
chr194130651641306567+3'-UTR,CDS3.636163.14867K562DDX55
chr194130709141307198+3'-UTR,CDS3.197774.33160K562FUS
chr194131253441312580+3'-UTR,CDS,intron-Distal,intron-Proximal3.111723.50044K562YBX3
chr194130685341306885+3'-UTR,CDS3.489103.73797K562CSTF2T
chr194131304141313059+3'-UTR,CDS,intron-Distal,intron-Proximal3.025643.07714K562YBX3
chr194131036941310516+intron-Distal3.711356.33414K562FUS
chr194130972141309765+intron-Distal3.144764.58795K562EWSR1
chr194131091841310997+intron-Distal3.486037.34646K562NONO
chr194131073841310806+intron-Distal3.819383.80037K562FUS
chr194131263141312685+intron-Distal,intron-Proximal4.067193.30664K562NONO
chr194130995441310112+intron-Distal3.505009.04624K562FUS
chr194130745841307510+intron-Distal4.149044.27402K562CSTF2T
chr194131092141310985+intron-Distal3.798474.81215K562EWSR1
chr194131128241311321+intron-Distal3.351864.48425K562CSTF2T
chr194131104641311108+intron-Distal3.541194.47051K562EWSR1
chr194130994341310073+intron-Distal3.603958.60539K562EWSR1
chr194131095741311083+intron-Distal3.063743.63437HepG2HNRNPM
chr194131091641311002+intron-Distal3.522668.66194K562CSTF2T
chr194130973541309776+intron-Distal3.372773.74491K562CSTF2T
chr194130805541308150+intron-Distal4.5797110.59779K562GTF2F1
chr194131258341312654+intron-Distal,intron-Proximal4.611515.68502HepG2PRPF8
chr194131089541310975+intron-Distal4.329295.52774K562FUS
chr194130818141308272+intron-Distal3.292975.64759K562NONO
chr194130827741308354+intron-Distal3.639676.95413HepG2PCBP2
chr194130519941305252+intron-Distal,intron-Proximal3.977543.94684HepG2CSTF2T
chr194131044941310511+intron-Distal3.092413.58403K562EWSR1
chr194130922641309262+intron-Distal,intron-Proximal3.419324.02206K562CSTF2T
chr194131290241313006+intron-Distal,intron-Proximal3.331946.01711K562CSTF2T
chr194130808041308147+intron-Distal3.110284.67846K562EWSR1
chr194130734241307361+intron-Proximal4.167365.63763K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EGLN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EGLN2 is not available on ENCORE database.

  • 73 RBPs can affect the levels of EGLN2.  








The Knockdown/knockout RNA-Seq assay for EGLN2 is not available on ENCORE database.





73 RBPs can affect the gene expression of EGLN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EGLN2ENSG00000269858.1698.11850506.184300.463702.445801.56000HepG2ABCF1
EGLN2ENSG00000269858.1735.83520495.327800.570907.486306.58560HepG2ACO1
EGLN2ENSG00000269858.1531.55190341.460900.638404.002302.75370HepG2AKAP8
EGLN2ENSG00000269858.1758.42840497.691300.607707.934206.71730HepG2AKAP8L
EGLN2ENSG00000269858.1479.41060314.627900.607504.194403.47490HepG2BOP1
EGLN2ENSG00000269858.1175.07850270.79660-0.629203.284002.45190HepG2CALR
EGLN2ENSG00000269858.1621.45820399.738400.636505.261004.42680HepG2CELF1
EGLN2ENSG00000269858.1687.22980490.227600.487202.680102.06300HepG2DDX3X
EGLN2ENSG00000269858.11129.43750835.058500.435605.258404.47650HepG2ETF1
EGLN2ENSG00000269858.1625.99050484.062500.370802.444601.65970HepG2EWSR1
EGLN2ENSG00000269858.1278.95980369.71630-0.406402.010501.33170HepG2FUBP3
EGLN2ENSG00000269858.1747.45020451.600900.726805.594304.63300HepG2FXR1
EGLN2ENSG00000269858.1634.78550418.754300.600103.417502.68170HepG2G3BP1
EGLN2ENSG00000269858.1358.61940232.935700.622403.065201.62580HepG2HNRNPA0
EGLN2ENSG00000269858.1365.42000239.041800.612203.728902.99490HepG2HNRNPA1
EGLN2ENSG00000269858.1345.14900227.441700.601603.028301.55860HepG2HNRNPAB
EGLN2ENSG00000269858.1414.84710262.454800.660403.848202.40210HepG2KHDRBS1
EGLN2ENSG00000269858.1720.60420479.858600.586503.250702.34780HepG2LARP4
EGLN2ENSG00000269858.1661.99920451.760000.551203.064902.37450HepG2MAGOH
EGLN2ENSG00000269858.1944.62810454.235401.0562011.8021010.56460HepG2MATR3
EGLN2ENSG00000269858.1251.73090347.21280-0.463902.476001.32990HepG2NAA15
EGLN2ENSG00000269858.1529.90470426.158800.314202.037201.38020HepG2NOL12
EGLN2ENSG00000269858.1574.32490332.003500.790603.393702.17400HepG2NONO
EGLN2ENSG00000269858.1513.79300251.607001.029906.502605.10380HepG2PABPC1
EGLN2ENSG00000269858.1252.20760328.34880-0.380601.969401.30890HepG2PRPF4
EGLN2ENSG00000269858.1620.24170429.348600.530604.935104.24820HepG2PTBP1
EGLN2ENSG00000269858.1624.91330406.819700.619205.674404.86100HepG2PUF60
EGLN2ENSG00000269858.1629.51300431.873200.543506.896506.04650HepG2PUM1
EGLN2ENSG00000269858.1868.99420431.547701.009704.250403.43000HepG2PUM2
EGLN2ENSG00000269858.11092.65720697.952600.646509.933309.08900HepG2RBM22
EGLN2ENSG00000269858.1509.27630328.617800.631903.453002.33870HepG2RBM27
EGLN2ENSG00000269858.1392.22730266.852900.555502.828201.75630HepG2RCC2
EGLN2ENSG00000269858.1840.77780477.821400.8152012.6389011.63820HepG2NELFE
EGLN2ENSG00000269858.1483.14600303.059900.672804.436003.43520HepG2RPS2
EGLN2ENSG00000269858.1390.64700276.561800.498202.214001.49790HepG2RPS3A
EGLN2ENSG00000269858.1486.36380309.372200.652604.112802.78850HepG2RPS5
EGLN2ENSG00000269858.1337.25160235.219800.519703.575102.85900HepG2SAFB2
EGLN2ENSG00000269858.1878.68970467.288900.910908.435707.20640HepG2SF3A3
EGLN2ENSG00000269858.1412.00670274.311600.586805.188304.35430HepG2SMN1
EGLN2ENSG00000269858.1373.00330466.57560-0.322901.920101.50570HepG2SRSF1
EGLN2ENSG00000269858.1604.92540401.694500.590606.729405.81040HepG2SRSF5
EGLN2ENSG00000269858.1401.01470240.651900.736604.603403.14710HepG2STIP1
EGLN2ENSG00000269858.1733.88490456.820800.6838010.271809.20170HepG2SUCLG1
EGLN2ENSG00000269858.1365.83850258.941400.498503.549302.92810HepG2TRIM56
EGLN2ENSG00000269858.1633.09060397.472000.671503.629202.61410HepG2TUFM
EGLN2ENSG00000269858.1695.40640437.084000.669803.017302.36200HepG2U2AF1
EGLN2ENSG00000269858.1567.79950227.625601.318603.350602.26070HepG2U2AF2
EGLN2ENSG00000269858.1707.02430420.735200.748702.661901.84070HepG2UBE2L3
EGLN2ENSG00000269858.1390.47020212.465100.877906.273005.12190HepG2UCHL5
EGLN2ENSG00000269858.1515.77980400.099400.366302.682402.09280HepG2UTP3
EGLN2ENSG00000269858.1243.47070324.01930-0.412302.326501.70360HepG2ZC3H8
EGLN2ENSG00000269858.12053.966501600.125500.360105.837305.06150K562AGGF1
EGLN2ENSG00000269858.12298.933501758.373900.386604.102702.85450K562AKAP8
EGLN2ENSG00000269858.12434.625102043.292300.252702.015601.49950K562AQR
EGLN2ENSG00000269858.12095.265602681.19370-0.355704.908803.60090K562CELF1
EGLN2ENSG00000269858.12336.482101466.923300.6714017.5315016.01480K562DDX47
EGLN2ENSG00000269858.11508.862701791.56300-0.247802.299801.51190K562DKC1
EGLN2ENSG00000269858.11821.035601570.321500.213601.936101.31580K562EIF2S2
EGLN2ENSG00000269858.1904.59150519.747900.7994011.9035010.23380K562EIF3G
EGLN2ENSG00000269858.11157.52080916.985800.336003.420002.11290K562EIF4B
EGLN2ENSG00000269858.12677.909202180.208100.296503.360202.32790K562EIF4G2
EGLN2ENSG00000269858.11325.95860953.484600.475704.629303.51150K562FIP1L1
EGLN2ENSG00000269858.1453.45280756.85180-0.739106.709504.82270K562FKBP4
EGLN2ENSG00000269858.11696.888301058.920600.6802014.1801012.91430K562FXR1
EGLN2ENSG00000269858.1149.65310358.75600-1.261409.581308.11050K562G3BP2
EGLN2ENSG00000269858.11225.08460784.296000.643306.053504.60940K562HNRNPM
EGLN2ENSG00000269858.11661.120401292.664800.361702.989302.16370K562HSPD1
EGLN2ENSG00000269858.1987.36890730.558000.434502.372801.52420K562MATR3
EGLN2ENSG00000269858.11002.658801314.23280-0.390402.606401.80150K562PCBP3
EGLN2ENSG00000269858.11531.015401082.453200.500105.099703.92850K562PPIG
EGLN2ENSG00000269858.11197.41500711.370700.751106.605205.61390K562PTBP1
EGLN2ENSG00000269858.11993.968402530.56450-0.343803.676302.43390K562PUM1
EGLN2ENSG00000269858.1929.22050681.764100.446602.569801.76190K562RBM22
EGLN2ENSG00000269858.1961.20260717.530800.421702.285601.31520K562NELFE
EGLN2ENSG00000269858.11105.52810780.376100.502402.264601.52890K562RPS19
EGLN2ENSG00000269858.11342.143801614.83350-0.266802.259001.51610K562SF3A3
EGLN2ENSG00000269858.1476.24870372.981200.352502.134001.38500K562SF3B4
EGLN2ENSG00000269858.1714.18240551.983800.371602.427201.45050K562SRSF4
EGLN2ENSG00000269858.11074.02830658.873100.704906.217704.53490K562SRSF5
EGLN2ENSG00000269858.11286.88260705.711100.866607.097205.91020K562TARDBP
EGLN2ENSG00000269858.11188.42750680.779400.803706.508605.17380K562TIA1
EGLN2ENSG00000269858.11012.33860668.419700.598803.042001.88860K562TRA2A
EGLN2ENSG00000269858.11432.124701735.03000-0.276802.875702.14290K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EGLN2 is not available on ENCORE database.





11 RBPs can affect the splicing of EGLN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSEGLN2ENSG00000269858.1chr19+413130424131345641313042413131794131371341314337-0.172000.000000.00087shorterK562SUPV3L1
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.213000.000000.00000includedK562PUS1
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.053000.005570.05461includedHepG2SF3A3
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.063000.004640.03222includedHepG2U2AF2
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.069000.000000.00000includedK562AGGF1
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.116000.000000.00011includedHepG2PCBP1
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.071000.000000.00000includedK562AKAP8L
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.083000.000190.00282includedHepG2U2AF1
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.058000.000010.00013includedK562RBM15
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.083000.000000.00000includedK562UTP18
RIEGLN2ENSG00000269858.1chr19+4131304241313456413130424131317941313388413134560.077000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EGLN2 is not avaliable on ENCORE database.