PMPCB

General Information

Gene Name       : PMPCB
Gene ID             : ENSG00000105819.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PMPCB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PMPCBENSG00000105819.1388.2968.6278.46ENCSR000AEF
HepG2PMPCBENSG00000105819.1352.5173.7563.13ENCSR985KAT
K562PMPCBENSG00000105819.1369.9478.3274.13ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PMPCB is not avaliable on ENCORE database.



Proteins bound to RNA
  • PMPCB RNA is bound by 16 proteins.  







eCLIP assay for PMPCB is not avaliable on ENCORE database.





16 proteins are bound to PMPCB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7102952502102952569+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.250863.72202HepG2G3BP1
chr7102952209102952298+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.6443114.88122K562EFTUD2
chr7102950881102950921+3'-UTR,5'-UTR,CDS3.225094.34695HepG2BCLAF1
chr7102952332102952346+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.343294.24111K562EFTUD2
chr7102952753102952847+3'-UTR,intron-Distal4.6553519.85511K562PUM2
chr7102952289102952344+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.661178.57930HepG2BCLAF1
chr7102952548102952611+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.3008511.69193K562EFTUD2
chr7102949438102949494+3'-UTR,5'-UTR,CDS3.399054.34695HepG2BCLAF1
chr7102952502102952590+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.909093.84295K562GRWD1
chr7102952551102952609+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal6.6379521.27094HepG2PRPF8
chr7102952625102952712+3'-UTR,CDS,intron-Distal,intron-Proximal3.525509.04979HepG2U2AF2
chr7102952094102952170+3'-UTR,5'-UTR,CDS,intron-Distal3.593394.98210K562SND1
chr7102952546102952615+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.4190912.02334K562PRPF8
chr7102952695102952802+3'-UTR,CDS,intron-Distal4.692414.95959K562CPSF6
chr7102952640102952696+3'-UTR,CDS,intron-Distal,intron-Proximal3.405905.18322K562U2AF2
chr7102940669102940733+5'-UTR,CDS4.461597.53358HepG2BCLAF1
chr7102939015102939082+5'-UTR,CDS3.927553.82000HepG2GRWD1
chr7102944290102944392+5'-UTR,CDS,intron-Distal,intron-Proximal4.193869.81070K562LIN28B
chr7102938005102938053+5'-UTR,CDS,intron-Proximal4.929354.65563K562AQR
chr7102939944102940011+5'-UTR,CDS,intron-Proximal4.542984.22101K562PRPF8
chr7102939020102939082+5'-UTR,CDS3.974553.98636K562LIN28B
chr7102944288102944364+5'-UTR,CDS,intron-Distal,intron-Proximal3.263226.50801HepG2BCLAF1
chr7102939035102939079+5'-UTR,CDS3.902274.93978HepG2BCLAF1
chr7102939945102939978+5'-UTR,CDS,intron-Proximal3.023584.34780K562ZNF622
chr7102940598102940654+5'-UTR,CDS,intron-Proximal3.831154.89208K562AQR
chr7102939888102939976+5'-UTR,CDS,intron-Proximal3.270175.12345HepG2GRWD1
chr7102940712102940730+5'-UTR,CDS3.108734.53299K562YBX3
chr7102939896102939979+5'-UTR,CDS,intron-Proximal3.544427.66871HepG2BCLAF1
chr7102940624102940644+5'-UTR,CDS,intron-Proximal4.372823.38968HepG2BCLAF1
chr7102939037102939155+5'-UTR,CDS3.3137713.22907HepG2SUB1
chr7102939962102940029+5'-UTR,CDS,intron-Proximal3.729085.83621K562AQR
chr7102940631102940722+5'-UTR,CDS,intron-Proximal3.490544.12796K562LIN28B
chr7102944901102944957+5'-UTR,CDS,intron-Proximal4.009743.56873HepG2PRPF8
chr7102944598102944663+intron-Distal3.288113.18246K562PRPF8
chr7102952202102952242+intron-Distal,intron-Proximal5.205714.40745K562SF3B4
chr7102951865102951948+intron-Distal3.855033.42844K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PMPCB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PMPCB is not available on ENCORE database.

  • 97 RBPs can affect the levels of PMPCB.  








The Knockdown/knockout RNA-Seq assay for PMPCB is not available on ENCORE database.





97 RBPs can affect the gene expression of PMPCB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PMPCBENSG00000105819.9984.214401437.64730-0.5467010.835109.79630HepG2ACO1
PMPCBENSG00000105819.92148.330502960.03000-0.462403.631103.03270HepG2AKAP1
PMPCBENSG00000105819.91288.737901873.74290-0.540004.560003.23450HepG2AKAP8
PMPCBENSG00000105819.91154.010301444.40620-0.323803.923103.02160HepG2AKAP8L
PMPCBENSG00000105819.91887.517102449.22930-0.375802.949702.13980HepG2ASCC1
PMPCBENSG00000105819.91577.172702426.49320-0.6215015.3004013.91610HepG2AUH
PMPCBENSG00000105819.91511.324202017.96190-0.417104.110603.39690HepG2BOP1
PMPCBENSG00000105819.91079.012101437.34020-0.413706.197505.27390HepG2CKAP4
PMPCBENSG00000105819.9968.011101514.57680-0.645802.842902.06700HepG2CNOT7
PMPCBENSG00000105819.91349.660901673.00250-0.309802.371501.34930HepG2CPSF7
PMPCBENSG00000105819.91969.398502294.53790-0.220403.079902.30420HepG2DAZAP1
PMPCBENSG00000105819.91282.778402835.59850-1.1444021.1642019.60240HepG2DDX3X
PMPCBENSG00000105819.91389.621802435.57000-0.809609.664208.58590HepG2DDX6
PMPCBENSG00000105819.91082.005001284.13960-0.247102.805802.14970HepG2DNAJC2
PMPCBENSG00000105819.91084.787501508.07310-0.475304.075002.97990HepG2EEF2
PMPCBENSG00000105819.9953.231901257.20700-0.399303.012801.85870HepG2EFTUD2
PMPCBENSG00000105819.9967.547402341.63830-1.2751024.9941023.33940HepG2EIF2S1
PMPCBENSG00000105819.91468.716402587.91420-0.817209.955908.76140HepG2EIF4A3
PMPCBENSG00000105819.91699.822602519.45220-0.567704.201103.36320HepG2EIF4B
PMPCBENSG00000105819.92640.983802263.696900.222302.719201.88800HepG2EIF4G1
PMPCBENSG00000105819.92273.092802785.94690-0.293504.405703.67820HepG2ETF1
PMPCBENSG00000105819.9836.880901404.84300-0.7473011.554209.87950HepG2EWSR1
PMPCBENSG00000105819.9833.481701094.14630-0.392603.767802.38250HepG2FAM120A
PMPCBENSG00000105819.91493.541501801.35990-0.270302.131901.43400HepG2FUBP3
PMPCBENSG00000105819.91497.439902610.70790-0.8019011.3489010.04440HepG2FXR1
PMPCBENSG00000105819.91604.314102422.01900-0.594305.976905.01540HepG2G3BP1
PMPCBENSG00000105819.92048.508202571.01630-0.327802.468001.62860HepG2G3BP2
PMPCBENSG00000105819.9845.465001090.01100-0.366502.432401.59660HepG2GEMIN5
PMPCBENSG00000105819.91075.110301467.25130-0.448603.474102.32440HepG2GNB2L1
PMPCBENSG00000105819.91464.238702100.07640-0.520304.650503.83330HepG2GPKOW
PMPCBENSG00000105819.91047.468701307.92300-0.320402.489201.87380HepG2HNRNPA1
PMPCBENSG00000105819.9787.420001454.84520-0.8857014.0051012.56100HepG2HNRNPC
PMPCBENSG00000105819.91979.474202452.03590-0.308902.428101.77200HepG2HNRNPK
PMPCBENSG00000105819.91503.712402462.00220-0.711309.019807.87930HepG2IGF2BP2
PMPCBENSG00000105819.91805.149202476.21740-0.456003.066802.00290HepG2KHSRP
PMPCBENSG00000105819.91753.264702481.04160-0.500903.810902.83320HepG2LARP4
PMPCBENSG00000105819.91272.117702611.61760-1.0377017.5270015.95120HepG2MAGOH
PMPCBENSG00000105819.91008.233202626.29780-1.3812026.2338024.46680HepG2MATR3
PMPCBENSG00000105819.91142.895702688.21320-1.2340023.1090021.39530HepG2NCBP2
PMPCBENSG00000105819.91647.499302275.25870-0.465807.098205.88600HepG2NOL12
PMPCBENSG00000105819.92363.291901777.048400.411203.880002.99780HepG2NSUN2
PMPCBENSG00000105819.9835.944401383.92960-0.727303.483202.47930HepG2PABPC1
PMPCBENSG00000105819.91187.565702394.26560-1.0116016.2911014.59570HepG2PABPC4
PMPCBENSG00000105819.91528.114002358.65240-0.6262015.9143014.65340HepG2PCBP1
PMPCBENSG00000105819.91392.299902400.02190-0.7856023.7286022.42410HepG2PTBP1
PMPCBENSG00000105819.91702.783802171.93170-0.351103.438902.78420HepG2PUF60
PMPCBENSG00000105819.91770.150002305.59910-0.381308.329507.41570HepG2PUM1
PMPCBENSG00000105819.91744.743602303.91640-0.401105.138504.23780HepG2PUM2
PMPCBENSG00000105819.91226.183401464.33780-0.256102.972302.33990HepG2PUS1
PMPCBENSG00000105819.91885.730702599.27260-0.463007.374506.42740HepG2QKI
PMPCBENSG00000105819.91824.410102328.53440-0.352004.917804.27680HepG2RBM22
PMPCBENSG00000105819.91784.108902359.01090-0.403004.658603.80400HepG2RBM25
PMPCBENSG00000105819.91426.912602670.98990-0.9045031.1478029.75080HepG2NELFE
PMPCBENSG00000105819.91906.612902487.67140-0.383806.753005.85120HepG2RECQL
PMPCBENSG00000105819.9834.131401191.22400-0.514105.591204.75200HepG2RPS19
PMPCBENSG00000105819.91133.337201598.52320-0.496204.623303.60400HepG2RPS2
PMPCBENSG00000105819.91429.516101862.28380-0.381501.913901.35070HepG2SF3A3
PMPCBENSG00000105819.91553.431802498.72390-0.6857018.7620017.43750HepG2SF3B4
PMPCBENSG00000105819.92309.455902629.99100-0.187502.246401.77960HepG2SRFBP1
PMPCBENSG00000105819.92182.530902608.13030-0.257003.699803.17300HepG2SRSF1
PMPCBENSG00000105819.91538.110502144.46350-0.479509.343708.28470HepG2SRSF5
PMPCBENSG00000105819.91593.628702121.85600-0.413007.819506.97660HepG2SRSF9
PMPCBENSG00000105819.91945.465602283.44970-0.231102.901102.37940HepG2SSB
PMPCBENSG00000105819.91891.659502438.84810-0.366507.250606.32430HepG2SUCLG1
PMPCBENSG00000105819.91569.639001953.39590-0.315602.467701.77740HepG2TARDBP
PMPCBENSG00000105819.91691.609102154.08100-0.348703.722902.75980HepG2TIA1
PMPCBENSG00000105819.91143.317501404.22070-0.296502.594302.10740HepG2TIAL1
PMPCBENSG00000105819.91737.979102121.88160-0.287902.578501.73720HepG2TUFM
PMPCBENSG00000105819.91702.529702245.97590-0.399703.090702.20600HepG2UBE2L3
PMPCBENSG00000105819.91242.225001651.55790-0.410906.872905.85330HepG2UPF1
PMPCBENSG00000105819.91304.074401594.51890-0.290103.553502.89040HepG2UTP3
PMPCBENSG00000105819.9901.896101361.09320-0.593702.868901.74720HepG2XPO5
PMPCBENSG00000105819.91499.873601207.998100.312102.198601.54630HepG2XRN2
PMPCBENSG00000105819.92050.185301573.526200.381707.295606.29050HepG2ZC3H8
PMPCBENSG00000105819.91068.823801816.40190-0.7651025.3198024.08450HepG2ZNF622
PMPCBENSG00000105819.94440.728003989.149700.154601.815201.33580K562AGGF1
PMPCBENSG00000105819.93099.317404004.23980-0.369603.911803.23810K562AQR
PMPCBENSG00000105819.93153.257502535.172600.314702.852301.32140K562CEBPZ
PMPCBENSG00000105819.97488.909006060.301500.305303.739902.59920K562CELF1
PMPCBENSG00000105819.91881.631801437.812300.388003.128201.71170K562DHX30
PMPCBENSG00000105819.93701.953004466.71760-0.270903.646902.62190K562DKC1
PMPCBENSG00000105819.91791.834401381.156700.375503.180801.73740K562DNAJC21
PMPCBENSG00000105819.91508.670501966.26190-0.382203.286502.28640K562EFTUD2
PMPCBENSG00000105819.92368.889702775.54820-0.228602.475001.78790K562EIF2S2
PMPCBENSG00000105819.91513.223002105.10960-0.476303.808302.57470K562EIF3D
PMPCBENSG00000105819.92443.001301938.201600.333803.639902.06970K562FUS
PMPCBENSG00000105819.91687.907202394.03480-0.504209.428708.39030K562FXR1
PMPCBENSG00000105819.93589.972902594.539200.468403.368002.57400K562G3BP2
PMPCBENSG00000105819.93131.150102674.535000.227302.389201.33780K562GLRX3
PMPCBENSG00000105819.93481.926602660.431800.388102.346901.36250K562HNRNPA1
PMPCBENSG00000105819.91540.078002593.51050-0.7519014.1982012.92840K562HNRNPC
PMPCBENSG00000105819.91990.608201341.836800.568905.918203.74610K562ILF3
PMPCBENSG00000105819.95456.317804405.161800.308603.290602.38360K562KIF1C
PMPCBENSG00000105819.92151.739402898.76820-0.429905.123803.97260K562MAGOH
PMPCBENSG00000105819.94635.456203458.995500.422302.991602.06800K562NAA15
PMPCBENSG00000105819.93528.412603124.354200.175402.904902.14310K562NSUN2
PMPCBENSG00000105819.91898.433602579.31000-0.442205.130903.78950K562PCBP2
PMPCBENSG00000105819.91993.647202816.28410-0.498407.339406.29500K562PTBP1
PMPCBENSG00000105819.93994.079505376.78580-0.428905.993904.79710K562PUF60
PMPCBENSG00000105819.96770.595305719.862400.243202.297901.33370K562PUM1
PMPCBENSG00000105819.95555.696004116.618200.432404.776504.08770K562PUS1
PMPCBENSG00000105819.94691.341004010.953900.226002.573501.99830K562RBM15
PMPCBENSG00000105819.91950.002802700.85150-0.469905.375004.15800K562RBM22
PMPCBENSG00000105819.92218.954702842.12730-0.357103.041301.88980K562NELFE
PMPCBENSG00000105819.92182.079303238.01760-0.569406.690105.04930K562RPS3
PMPCBENSG00000105819.92150.651702697.68370-0.326903.775102.77110K562SF3B4
PMPCBENSG00000105819.91789.691801414.693000.339102.601401.37930K562SLBP
PMPCBENSG00000105819.92784.723603158.42890-0.181702.473901.58340K562SRPK2
PMPCBENSG00000105819.92552.506603126.27320-0.292502.852801.77940K562SRSF4
PMPCBENSG00000105819.93048.929202600.519400.229402.473001.37020K562SRSF7
PMPCBENSG00000105819.92915.392902261.447500.366305.425503.52080K562SSB
PMPCBENSG00000105819.93236.894902597.254300.317503.684502.75340K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PMPCB is not available on ENCORE database.





16 RBPs can affect the splicing of PMPCB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.094000.000000.00002excludedK562SRSF1
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.245000.000050.00150excludedHepG2U2AF1
SEPMPCBENSG00000105819.9chr7+1029480421029481551029448571029449371029493981029495420.102000.000060.05882includedK562TROVE2
SEPMPCBENSG00000105819.9chr7+1029480421029481551029448571029449371029493981029495420.178000.000180.04697includedK562METAP2
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.073000.000560.00747excludedK562AQR
SEPMPCBENSG00000105819.9chr7+1029480421029481551029448571029449371029493981029495420.167000.000530.07107includedK562DROSHA
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.109000.000030.00095excludedK562PUS1
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.239000.000000.00295excludedK562DHX30
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.067000.005160.08325excludedK562U2AF1
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.130000.000220.03196excludedHepG2PCBP2
SEPMPCBENSG00000105819.9chr7+1029480421029481551029448571029449371029493981029495420.065000.001310.08042includedHepG2HNRNPL
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.096000.000140.00741excludedK562UTP18
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.064000.006030.08360excludedK562U2AF2
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.068000.000060.00382excludedK562TARDBP
SEPMPCBENSG00000105819.9chr7+102948042102948155102944857102944937102949398102949542-0.325000.000000.00000excludedK562HNRNPC
A3SSPMPCBENSG00000105819.9chr7+102944288102944487102944432102944487102940624102940754-0.144000.000120.03673shorterK562SUPV3L1
A3SSPMPCBENSG00000105819.9chr7+102944288102944487102944432102944487102940624102940754-0.137000.000010.03655shorterK562LIN28B
A3SSPMPCBENSG00000105819.9chr7+102944288102944487102944432102944487102940624102940754-0.128000.000000.00079shorterK562DROSHA
A3SSPMPCBENSG00000105819.9chr7+102944288102944487102944432102944487102940624102940754-0.086000.002000.07648shorterK562U2AF1
A3SSPMPCBENSG00000105819.9chr7+102944288102944487102944432102944487102940624102940754-0.142000.000150.02340shorterK562HNRNPC
A5SSPMPCBENSG00000105819.9chr7+1029379021029384001029379021029380051029390141029391550.087000.000000.00000longerK562HNRNPC
A5SSPMPCBENSG00000105819.9chr7+1029379021029384001029379021029380051029390141029391550.058000.000000.00003longerK562U2AF2
MXEPMPCBENSG00000105819.9chr7+1029444321029444871029480421029481551029406241029407541029493981029495420.105000.001420.025911includedK562U2AF1
MXEPMPCBENSG00000105819.9chr7+1029448571029449371029480421029481551029442881029444871029493981029495420.074000.000450.010561includedK562U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PMPCB is not avaliable on ENCORE database.