NIPBL

General Information

Gene Name       : NIPBL
Gene ID             : ENSG00000164190.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NIPBL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NIPBLENSG00000164190.1726.4920.3223.41ENCSR000AEF
HepG2NIPBLENSG00000164190.1713.1216.4914.80ENCSR985KAT
K562NIPBLENSG00000164190.1722.8426.3324.59ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 565ENCSR891RICNIPBLK562ReleasedENCAB695MXGENCSR816NVJ  
knockdown followed by RNA-seq NIPBL-BGKcLV08-K562ENCSR999DVKNIPBLK562ReleasedENCSR015KGT   CRISPRKD% = 64.5,64.4






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
NIPBL565K562ENCSR891RICENCSR816NVJENCAB695MXGcustom (Yokomori lab)--ReleasedENCODE4


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
NIPBLENCAB695MXGKY_SCC2C_0193015Released, ENCODE3Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
NIPBLK562CRISPRBGKcLV06-17,BGKcLV06-18BGKcLV06-1,BGKcLV06-2no clear band,NotSatisfiedENCODE3
NIPBLK562CRISPRENCSR999DVKENCSR015KGTNIPBL-BGKcLV08-43,NIPBL-BGKcLV08-44NT-BGKcLV08-1,NT-BGKcLV08-264.5,64.4ReleasedENCODE4
NIPBLK562CRISPRBGKcLV08-45,BGKcLV08-46BGKcLV08-1,BGKcLV08-254.8,38.9NotSatisfiedENCODE4
NIPBLHepG2CRISPRBGHcLV07-17,BGHcLV07-18BGHcLV07-1,BGHcLV07-2NotSatisfiedENCODE4bad KD%
NIPBLHepG2CRISPRBGHcLV10-33,BGHcLV10-34BGHcLV10-1,BGHcLV10-20.0,0.0NotSatisfiedENCODE4
NIPBLHepG2CRISPRBGHcLV10-35,BGHcLV10-36BGHcLV10-1,BGHcLV10-20.0,0.0NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
NIPBLProduct_ID: KY_SCC2C_01
Lot_ID: 93015
Source: Kyoko Yokomori
Target Name: NIPBL-human		 K562_Custom_NIPBL_MassSpec.png<br>Caption: Representative image of immunoprecipitation performed on whole cell extracts from the K562 cell line using the NIPBL-specific antibody KY_SCC2C_01. Lane 1: Input from IP using control IgG. Lane 2: Immunoprecipitated material using control IgG. Lane 3: Input from IP using NIPBL antibody. Lane 4: Immunoprecipitated material using NIPBL antibody. Outlined regions were excised from gel and subjected to analysis by mass spectrometry. Target molecular weight: 316 kDa.
K562_KY_SCC2C_01_93015_NIPBL.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using NIPBL specific antibody. Samples were run on a 3-8% Tris-Acetate with Spectra High Range Ladder. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-NIPBL antibody (lanes under 'NIPBL').
 NIPBL%20K562.pdf








RNA Targets
  • NIPBL protein binds to 295 RNA regions.  





Proteins bound to RNA
  • NIPBL RNA is bound by 40 proteins.  






NIPBL protein has 295 RNA targets:

Only display 100 entries as example. Please click "View All" button to see all 295 entries.     

RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
NIPBLchr116582698565827039+3.0979813.71620K562SF3B2CDS,intron-Proximal
NIPBLchr33944998539450031+4.8637684.41837K562RPSAintron-Distal,intron-Proximal
NIPBLchr4436109436217-3.1701211.24213K562ZNF721, ABCA11PCDS,intron-Distal
NIPBLchr7139025474139025530+3.120957.25345K562C7orf55, C7orf55-LUC7L2intron-Distal
NIPBLchr11811683811744+4.5756943.43907K562RPLP2intron-Proximal
NIPBLchr168904271389042776-3.546168.23158K562CBFA2T3intron-Distal
NIPBLchr116781077367810888+3.547569.27813K562TCIRG15'-UTR,CDS,intron-Distal,intron-Proximal
NIPBLchr2187368864187368956+3.4429310.02733K562ZC3H153'-UTR,CDS,intron-Proximal
NIPBLchr134591162345911679-3.2101511.70748K562TPT1CDS,intron-Distal
NIPBLchr17625518576255220+4.9018627.67650K562RABGGTBintron-Distal
NIPBLchr7119437151119437186-4.386603.43367K562RP11-328J2.1intron-Distal
NIPBLchr93712686837126958+3.1938811.21124K562ZCCHC7CDS,intron-Distal,intron-Proximal
NIPBLchr6133138406133138459+4.8223278.83348K562RPS12intron-Distal
NIPBLchr116262115962621183-3.8240626.32646K562SNHG1intron-Distal,intron-Proximal
NIPBLchr191797348717973520+3.0225321.21917K562RPL18Aintron-Distal
NIPBLchrX2015417320154211-5.0218018.99792K562EIF1AXintron-Distal
NIPBLchr35272542352725462+4.905345.97506K562GNL3intron-Distal,intron-Proximal
NIPBLchr4770576770638-3.050659.59915K562RP11-440L14.1intron-Distal
NIPBLchr2232321158232321236-5.0870251.23916K562NCLintron-Distal
NIPBLchr119345490393454950+3.52087400.00000K562KIAA1731intron-Distal
NIPBLchr24738885847388900-3.038917.30938K562CALM2, RP11-761B3.13'-UTR,CDS,intron-Distal,intron-Proximal
NIPBLchr79163243891632534+3.262648.23158K562AKAP9CDS
NIPBLchr187568941875689492-3.164218.50657K562LINC01029intron-Distal
NIPBLchr61626628716266329+4.1936579.25091K562GMPRintron-Distal
NIPBLchr1722324402232477-5.6663117.90739K562TSR1intron-Distal
NIPBLchr1152908785290908-3.3141822.40169K562HBG2, HBE1CDS,intron-Distal,intron-Proximal
NIPBLchr167282159372821655-3.2506112.75733K562ZFHX3CDS,intron-Distal
NIPBLchr17625356276253655+4.0204330.83711K562RABGGTBintron-Distal
NIPBLchr5138614499138614538+3.6954826.32646K562MATR3intron-Distal,intron-Proximal
NIPBLchr156679569866795730-3.0716713.03653K562RPL43'-UTR,CDS,intron-Distal
NIPBLchr1214818015214818039+5.458796.19572K562CENPFCDS
NIPBLchr1270765027076531-3.3260635.93233K562PHB2intron-Distal,intron-Proximal
NIPBLchr119346467593464736-3.882377.57155K562TAF1Dintron-Distal
NIPBLchr8124348612124348662-4.013896.84905K562ATAD23'-UTR,CDS,intron-Distal,intron-Proximal
NIPBLchr63180487231804904+3.0217216.51506K562C6orf485'-UTR,intron-Distal
NIPBLchr9136217722136217756+5.7429631.21223K562RPL7Aintron-Distal
NIPBLchr7150070129150070211+3.347608.63694K562REPIN1, ZNF7753'-UTR,intron-Distal
NIPBLchr1780768138076864-3.0969136.57482K562TMEM1073'-UTR,intron-Distal
NIPBLchr63179774431797846+3.3203714.07094K562HSPA1B3'-UTR
NIPBLchr7120897160120897215+4.344626.35873K562CPED1intron-Distal
NIPBLchr127644984876449864-3.2502925.02175K562NAP1L13'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
NIPBLchr4774864774959-3.444345.54910K562RP11-440L14.1intron-Distal
NIPBLchr127644879976448870-3.1881152.64549K562NAP1L1CDS,intron-Distal,intron-Proximal
NIPBLchr14524218245242203+4.5256713.15684K562RPS8intron-Distal
NIPBLchr111709735517097381-4.9130039.23182K562RPS13intron-Distal
NIPBLchr62605643826056473-3.4833926.24690K562HIST1H1CCDS
NIPBLchr8144940621144940687-3.180899.73639K562EPPK1CDS,intron-Distal
NIPBLchr124904822249048248-3.497809.27813K562KANSL2intron-Distal
NIPBLchr1152910305291044-3.6004219.92158K562HBG2, HBE1CDS,intron-Distal
NIPBLchr14103804235103804313+3.697448.89650K562EIF5intron-Distal
NIPBLchr116262210362622137-5.6576740.75061K562SNHG1intron-Distal,intron-Proximal
NIPBLchr165858246158582529-3.4751516.38439K562CNOT1intron-Distal
NIPBLchr1892555459255600+3.408607.61338K562ANKRD123'-UTR,CDS
NIPBLchr13107196129107196177-3.8525912.35620K562ARGLU13'-UTR,intron-Distal,intron-Proximal
NIPBLchr4775192775259-4.166317.88492K562RP11-440L14.1intron-Distal
NIPBLchr156679359866793648-5.3963817.24802K562RPL4intron-Distal,intron-Proximal
NIPBLchr203037007130370108+3.322437.00334K562TPX2CDS
NIPBLchr173855687038556887-3.499018.42595K562TOP2ACDS,intron-Distal
NIPBLchr172704756527047635+5.7317243.93896K562RPL23A5'-UTR,intron-Distal,intron-Proximal
NIPBLchr3184052810184052908+3.194187.61338K562EIF2B5, EIF4G13'-UTR,intron-Distal
NIPBLchr79847942998479433+4.1615547.90921K562TRRAPintron-Distal
NIPBLchr177980140279801492-3.1361110.14382K562P4HB3'-UTR,CDS,intron-Distal
NIPBLchr79847939398479427+4.4350135.73443K562TRRAPintron-Distal
NIPBLchr5111497210111497315+3.4928918.84336K562EPB41L4A-AS1intron-Distal,intron-Proximal
NIPBLchr156679558966795639-4.1748518.99792K562RPL4intron-Distal,intron-Proximal
NIPBLchrX7307155973071617-3.5181229.69443K562XISTintron-Distal
NIPBLchrX7307169173071773-3.2280839.93081K562XISTintron-Distal
NIPBLchr9127623775127623825-3.1250812.14995K562RPL35CDS,intron-Distal
NIPBLchr111709619717096242-3.852928.88028K562RPS13intron-Distal
NIPBLchr61626608316266134+4.95808400.00000K562GMPRintron-Distal
NIPBLchr139200279592002862+3.2363323.60704K562MIR17HGintron-Distal
NIPBLchr3160232763160232788-3.13469400.00000K562KPNA4intron-Distal
NIPBLchr79847947198479510+3.2157057.96269K562TRRAPintron-Distal,intron-Proximal
NIPBLchr1266196836619715+6.1098841.77139K562NCAPD2intron-Distal,intron-Proximal
NIPBLchr2234184493234184584+3.1530834.46969K562ATG16L1intron-Distal
NIPBLchr129588881295888904+3.034287.38837K562METAP2CDS
NIPBLchr10101996803101996836-5.755085.04438K562CWF19L1intron-Distal,intron-Proximal
NIPBLchrX118921367118921426-4.6218622.83732K562RPL39intron-Distal,intron-Proximal
NIPBLchr139200327292003313+4.8738311.34739K562MIR17HGintron-Distal
NIPBLchr3186504529186504550+3.1856787.66039K562EIF4A2intron-Distal,intron-Proximal
NIPBLchr111082303410823061-4.4599853.28353K562EIF4G2intron-Distal
NIPBLchr116262139562621418-3.7122833.08613K562SNHG1intron-Distal,intron-Proximal
NIPBLchr1173836020173836068-5.7512848.40777K562GAS5intron-Distal,intron-Proximal
NIPBLchr61626641216266480+5.32412400.00000K562GMPRintron-Distal
NIPBLchr204789685947896874+4.2626411.06575K562ZFAS1intron-Distal
NIPBLchrX135961355135961384-4.862296.92303K562RBMXintron-Distal,intron-Proximal
NIPBLchr79847943998479452+3.77339400.00000K562TRRAPintron-Distal
NIPBLchr7107145023107145106-6.055128.45952K562COG5intron-Distal
NIPBLchr1154830175483120-3.0537310.43379K562HBE1, HBG2, AC104389.28intron-Distal
NIPBLchr5170814990170815010+3.025677.85614K562NPM15'-UTR,CDS
NIPBLchr1780767588076771-3.949833.85523K562TMEM1073'-UTR,intron-Distal
NIPBLchr116262276262622837-3.0277224.88157K562SNHG1intron-Distal,intron-Proximal
NIPBLchr1628143292814374+3.392908.86534K562SRRM2CDS,intron-Distal
NIPBLchrX7149539371495409-3.631128.26516K562RPS4XCDS,intron-Distal,intron-Proximal
NIPBLchr116262082662620860-3.0207823.99594K562SNHG1intron-Distal
NIPBLchr14102549370102549377-3.6390932.88773K562HSP90AA13'-UTR,CDS,intron-Distal,intron-Proximal
NIPBLchr172078783220787887+4.084566.52318K562RP11-344E13.3intron-Distal
NIPBLchrX7079355270793659+3.122727.38837K562OGT3'-UTR,CDS
NIPBLchr1266196666619683+5.2444265.15900K562NCAPD2intron-Distal
NIPBLchr3186504625186504641+4.084567.99680K562EIF4A2intron-Distal




40 proteins are bound to NIPBL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr53706411037064193+3'-UTR,CDS,intron-Distal,intron-Proximal3.514575.35459K562KHSRP
chr53706519737065238+3'-UTR4.847379.25286K562PUM2
chr53706546537065537+3'-UTR4.249868.29571K562PUM2
chr53687722036877282+5'-UTR,intron-Proximal3.723015.35682HepG2GRWD1
chr53687708336877119+5'-UTR3.849623.15006K562RBM15
chr53687711936877192+5'-UTR5.523879.33028K562RBM15
chr53695376936953804+5'-UTR,CDS3.200854.31744K562YBX3
chr53687702336877135+5'-UTR3.881544.61051HepG2DDX3X
chr53697096536971023+CDS,intron-Proximal4.392644.20763HepG2U2AF2
chr53697607036976146+CDS3.316415.63070K562RBM15
chr53704627037046295+CDS4.026889.37631HepG2BCLAF1
chr53700091837000965+CDS,intron-Proximal3.080313.40321HepG2GRWD1
chr53697109336971139+CDS,intron-Proximal5.6911414.93025K562LIN28B
chr53703648137036506+CDS4.576309.47159HepG2BCLAF1
chr53700276337002795+CDS,intron-Proximal4.680874.56100HepG2FXR2
chr53701626637016359+CDS,intron-Proximal3.853344.49024K562AQR
chr53697600036976069+CDS3.210906.50677K562UCHL5
chr53700110337001181+CDS,intron-Proximal5.9766227.62668HepG2BCLAF1
chr53699579636995842+CDS4.2910714.68146HepG2BCLAF1
chr53700336237003427+CDS,intron-Proximal4.9985911.80957HepG2BCLAF1
chr53698592136985974+CDS3.862558.25092HepG2BCLAF1
chr53697598836976041+CDS4.2041511.06379K562ZNF622
chr53706404337064115+CDS,intron-Proximal5.7586312.59025K562UCHL5
chr53700114837001180+CDS3.950305.77244K562UCHL5
chr53700091837000949+CDS,intron-Proximal3.036504.07771K562ZNF622
chr53695557736955612+CDS3.1322113.86230K562YBX3
chr53701021437010249+CDS3.227253.68829K562YBX3
chr53700276237002856+CDS,intron-Proximal6.0738731.03767HepG2BCLAF1
chr53700092337000984+CDS4.109865.09222HepG2FXR2
chr53698588736985962+CDS3.066728.73187K562ZNF622
chr53700092037000940+CDS4.264314.16170K562UCHL5
chr53696222336962272+CDS,intron-Proximal3.648488.70026K562IGF2BP1
chr53695385736953862+CDS3.2440114.40828K562YBX3
chr53701479937014857+CDS3.368999.84433HepG2BCLAF1
chr53700742437007455+CDS,intron-Proximal5.8652712.19672HepG2BCLAF1
chr53702633537026383+CDS4.112538.79898HepG2BCLAF1
chr53702743637027497+CDS,intron-Proximal3.993206.86590K562SF3B4
chr53695557336955577+CDS,intron-Proximal3.2566014.61901K562YBX3
chr53696162136961685+CDS3.836106.79446K562IGF2BP1
chr53698626236986317+CDS3.846598.81620HepG2BCLAF1
chr53704474337044769+CDS3.512877.83567HepG2BCLAF1
chr53701018937010234+CDS4.385599.80976HepG2BCLAF1
chr53698537336985406+CDS4.906365.87202K562UCHL5
chr53698567036985734+CDS3.676725.11155K562YBX3
chr53696222336962226+CDS,intron-Proximal3.203767.45337K562IGF2BP2
chr53701712037017143+CDS,intron-Proximal4.8006211.13876HepG2BCLAF1
chr53699573536995837+CDS3.314785.62825HepG2FXR2
chr53698485236984902+CDS4.169403.81597K562RBM15
chr53700272937002792+CDS,intron-Proximal4.179134.81549K562GPKOW
chr53697607836976135+CDS3.289336.02988K562UCHL5
chr53697097736970983+CDS,intron-Proximal3.345843.31745K562ZNF622
chr53704875437048773+CDS4.405357.09561HepG2BCLAF1
chr53698536736985400+CDS3.304975.35144K562ZNF622
chr53705254237052634+CDS3.967073.55391K562FXR1
chr53700057737000671+CDS3.567805.11425HepG2AGGF1
chr53701619437016252+CDS4.8771015.10546HepG2BCLAF1
chr53700061137000671+CDS3.091398.91165HepG2BCLAF1
chr53705256937052661+CDS4.973936.89655K562FXR2
chr53700117337001265+CDS,intron-Proximal3.5929310.82062K562AQR
chr53700664737006690+CDS4.2502614.60232HepG2BCLAF1
chr53698631736986395+CDS4.5559817.55697HepG2BCLAF1
chr53700649237006607+CDS4.3840028.62137HepG2BCLAF1
chr53704875937048773+CDS3.395613.61259K562ZNF622
chr53698627136986316+CDS4.015753.26507K562MTPAP
chr53700344637003547+CDS,intron-Proximal3.191094.76345K562KHSRP
chr53697598936976038+CDS4.6066914.51957HepG2BCLAF1
chr53698519336985296+CDS3.394138.33275HepG2FXR2
chr53702642437026481+CDS,intron-Proximal3.649864.41130K562AQR
chr53698491736984977+CDS3.2230410.17043HepG2BCLAF1
chr53702641437026429+CDS4.5915210.13662HepG2BCLAF1
chr53701625237016272+CDS5.0803412.89578HepG2BCLAF1
chr53697593036975989+CDS3.083839.95292HepG2BCLAF1
chr53697199736972066+CDS,intron-Proximal4.798914.90235K562SF3B4
chr53695382836953857+CDS3.1508716.25476K562YBX3
chr53704621337046223+CDS4.068985.35703HepG2BCLAF1
chr53700115637001177+CDS4.265833.29312HepG2FXR2
chr53704925437049276+CDS4.223047.16838HepG2BCLAF1
chr53698625336986391+CDS3.866658.60107HepG2FXR2
chr53696222336962265+CDS,intron-Proximal3.753795.85910HepG2IGF2BP1
chr53704871137048739+CDS3.520797.89260HepG2BCLAF1
chr53704627637046358+CDS,intron-Proximal4.781533.70131HepG2PRPF8
chr53704926837049373+CDS3.590128.04783K562YBX3
chr53700276237002825+CDS,intron-Proximal4.1443610.03782K562ZNF622
chr53696234336962377+CDS,intron-Proximal4.460498.94008K562ZNF622
chr53700091937000945+CDS3.080346.91034HepG2BCLAF1
chr53704869937048768+CDS5.643879.79220HepG2FXR2
chr53698562236985670+CDS4.146666.76362K562YBX3
chr53702746037027510+CDS,intron-Proximal3.6301112.82134HepG2BCLAF1
chr53706389837064006+CDS4.7084610.01989K562UCHL5
chr53697102836971093+CDS5.9937117.37647K562LIN28B
chr53702234537022392+CDS,intron-Proximal3.9544310.98590HepG2BCLAF1
chr53701027237010300+CDS3.787867.23562HepG2BCLAF1
chr53705908637059212+CDS3.745723.55204K562FXR1
chr53700649637006600+CDS3.390706.39282HepG2GRWD1
chr53698626136986308+CDS3.734255.33504HepG2HLTF
chr53700062337000672+CDS4.012853.60441HepG2GRWD1
chr53696222636962270+CDS3.5310910.27951K562IGF2BP2
chr53697619736976261+CDS3.1653013.21046HepG2BCLAF1
chr53697627836976302+CDS3.475843.61259K562ZNF622
chr53700336237003365+CDS,intron-Proximal3.778323.01428K562UCHL5
chr53702745937027507+CDS,intron-Proximal3.078283.90681K562DDX24
chr53697103436971115+CDS4.069214.24698K562IGF2BP1
chr53700880637008818+CDS4.622557.09561HepG2BCLAF1
chr53695814936958246+CDS,intron-Proximal3.4212612.09266K562SF3B4
chr53698562936985717+CDS3.127347.02083HepG2HLTF
chr53700815637008174+CDS4.969146.58593HepG2BCLAF1
chr53698490436984967+CDS4.480145.16052K562RBM15
chr53702746137027516+CDS,intron-Proximal3.356564.21853HepG2EIF3D
chr53699586436995904+CDS5.9423512.88829HepG2BCLAF1
chr53697626036976354+CDS5.3322710.23340K562RBM15
chr53697096936971034+CDS,intron-Proximal3.661703.25055K562U2AF2
chr53706402637064099+CDS,intron-Proximal3.656415.65606HepG2FXR2
chr53697618436976320+CDS4.6070010.51368K562IGF2BP1
chr53698533936985429+CDS4.3365012.93761HepG2BCLAF1
chr53700052537000631+CDS3.048268.72239K562UCHL5
chr53705191237051935+CDS3.398814.94406K562YBX3
chr53704566637045698+CDS3.182278.02162HepG2BCLAF1
chr53704473737044756+CDS,intron-Proximal3.094594.03389K562ZNF622
chr53699572636995796+CDS3.8421218.97241HepG2BCLAF1
chr53698602736986042+CDS3.469145.76104HepG2BCLAF1
chr53701024937010301+CDS3.512297.24294K562YBX3
chr53702065937020703+CDS3.902243.82000HepG2GRWD1
chr53700113337001177+CDS3.921247.71102K562ZNF622
chr53695567736955740+CDS,intron-Proximal3.404134.29472K562IGF2BP1
chr53696227036962352+CDS3.625834.30970K562IGF2BP2
chr53700111537001180+CDS3.346564.65365HepG2GRWD1
chr53696166336961686+CDS,intron-Proximal3.390793.75909HepG2IGF2BP1
chr53697699336977123+intron-Distal3.410703.43829K562EXOSC5
chr53695350336953593+intron-Distal4.231484.72162K562KHSRP
chr53698668836986746+intron-Distal3.699065.56048K562KHSRP
chr53697855936978607+intron-Distal5.258279.02315K562EXOSC5
chr53703672737036796+intron-Distal3.068533.68839K562KHSRP
chr53697670936976808+intron-Distal4.480725.07255HepG2KHSRP
chr53687743736877556+intron-Distal6.1418216.18814K562XRN2
chr53687742836877546+intron-Distal3.033967.63935HepG2HNRNPM
chr53688567436885733+intron-Distal4.012846.81238K562ZNF622
chr53693786336937933+intron-Distal5.120578.71243HepG2QKI
chr53687745136877536+intron-Distal4.3861610.65737HepG2XRN2
chr53697082736970905+intron-Distal,intron-Proximal4.281004.76003K562KHSRP
chr53697885936978894+intron-Distal5.9158314.65278K562EXOSC5
chr53688634836886453+intron-Distal4.643814.93122K562SLTM
chr53702534137025440+intron-Distal3.868263.24603K562KHSRP
chr53695864336958730+intron-Distal3.355034.35650K562KHSRP
chr53697771636977805+intron-Distal4.2394811.23512K562EXOSC5
chr53697660736976764+intron-Distal4.8496614.00650K562KHSRP
chr53692419736924304+intron-Distal4.363554.55788HepG2QKI
chr53691330336913364+intron-Distal3.447586.87041K562KHSRP
chr53688425036884310+intron-Distal4.536755.04769HepG2PTBP1
chr53697938236979420+intron-Distal5.186978.36716K562EXOSC5
chr53688626736886349+intron-Distal3.149575.26696K562UCHL5
chr53697252636972774+intron-Distal3.726063.06015K562MATR3
chr53688871336888811+intron-Distal3.620295.56048K562KHSRP
chr53700351237003598+intron-Distal,intron-Proximal3.540377.74495HepG2U2AF2
chr53696185936961936+intron-Distal3.820136.19377K562KHSRP
chr53697248936972623+intron-Distal5.051645.89856K562PTBP1
chr53690262036902708+intron-Distal4.265743.27829HepG2MATR3
chr53687744236877562+intron-Distal3.6198812.49524HepG2NKRF
chr53691054836910665+intron-Distal4.015273.62025K562MATR3
chr53687757536877655+intron-Distal5.146897.72419HepG2NKRF
chr53693109236931140+intron-Distal3.958653.27946HepG2HNRNPM
chr53692416736924235+intron-Distal4.507035.91698K562KHSRP
chr53699452836994575+intron-Distal3.815215.14864K562KHSRP
chr53693277236932840+intron-Distal3.070523.11628K562KHSRP
chr53697972636979775+intron-Distal4.507028.51196K562EXOSC5
chr53689833536898456+intron-Distal3.751549.43335K562KHDRBS1
chr53692587636925994+intron-Distal3.635234.51074HepG2HNRNPL
chr53697966936979691+intron-Distal4.534544.80466K562EXOSC5
chr53687915936879222+intron-Distal4.719036.08953K562EXOSC5
chr53687745836877555+intron-Distal4.529694.53244K562HNRNPM
chr53702039237020506+intron-Distal,intron-Proximal3.023835.34873K562KHSRP
chr53697797736978014+intron-Distal3.982566.10949K562EXOSC5
chr53690265236902709+intron-Distal4.253423.79026K562HNRNPM
chr53705083137050903+intron-Distal3.749903.19036K562HNRNPL
chr53700188637001965+intron-Distal4.044974.37030K562KHSRP
chr53697907736979120+intron-Distal3.720528.17180K562EXOSC5
chr53688648436886542+intron-Distal4.895614.43680K562ZNF622
chr53693085536930906+intron-Distal4.007023.01445K562EXOSC5
chr53697756036977621+intron-Distal3.223635.34873K562KHSRP
chr53699459436994624+intron-Distal3.135396.21868K562KHSRP
chr53704947537049567+intron-Distal,intron-Proximal3.777734.35635K562PRPF8
chr53690220036902257+intron-Distal4.5277610.61559K562EXOSC5
chr53697156936971680+intron-Distal3.159317.44686K562KHSRP
chr53696203136962119+intron-Distal4.503055.62258K562KHSRP
chr53697897036979011+intron-Distal3.118215.98067K562EXOSC5
chr53689938236899519+intron-Distal3.319125.78064K562KHSRP
chr53699496236995027+intron-Distal4.408238.75974K562KHSRP
chr53704411637044250+intron-Distal3.465084.56724K562KHSRP
chr53692473036924817+intron-Distal4.533195.44904K562TARDBP
chr53697959036979641+intron-Distal5.7677511.99536K562EXOSC5
chr53696527936965402+intron-Distal3.260013.07152HepG2HLTF
chr53689555536895641+intron-Distal3.351014.33009HepG2SUGP2
chr53702008437020180+intron-Distal3.225113.93901K562KHSRP
chr53697920536979227+intron-Distal3.651774.91094K562EXOSC5
chr53693096936931043+intron-Distal3.024145.36888K562KHSRP
chr53690260736902705+intron-Distal4.124593.90241K562MATR3
chr53699891436999022+intron-Distal4.635235.88023HepG2HNRNPL
chr53699503836995146+intron-Distal3.5092310.15825K562KHSRP
chr53697676436976824+intron-Distal3.157534.76345K562KHSRP
chr53697872436978765+intron-Distal4.9234612.87128K562EXOSC5
chr53688541736885536+intron-Distal4.130133.58955HepG2SRSF9
chr53688602236886121+intron-Distal4.697465.42152HepG2GRWD1
chr53697785436977922+intron-Distal4.4068712.46063K562EXOSC5
chr53690262636902682+intron-Distal4.206986.41051K562EXOSC5
chr53702957137029709+intron-Distal3.076664.61304K562KHSRP
chr53700595037006047+intron-Distal3.140953.11628K562KHSRP
chr53697945936979499+intron-Distal5.093768.36828K562EXOSC5
chr53690325536903314+intron-Distal4.566604.80466K562EXOSC5
chr53705705137057182+intron-Distal3.362069.15475HepG2PCBP2
chr53693204836932093+intron-Distal3.578403.02234K562KHSRP
chr53699595936996023+intron-Distal,intron-Proximal4.064383.49003K562PRPF8
chr53699462436994684+intron-Distal3.218847.14496K562KHSRP
chr53690792436907981+intron-Distal3.695093.08967K562KHDRBS1
chr53695941036959512+intron-Distal3.098856.21868K562KHSRP
chr53692461436924697+intron-Distal3.204803.39857HepG2HNRNPM
chr53697820236978244+intron-Distal4.0668110.31345K562EXOSC5
chr53696180836961859+intron-Distal3.959323.02234K562KHSRP
chr53697168036971738+intron-Distal3.572867.08481K562KHSRP
chr53692398536924087+intron-Distal3.191837.36118K562KHSRP
chr53688426136884314+intron-Distal4.209224.69074K562PTBP1
chr53697881036978851+intron-Distal4.088219.39208K562EXOSC5
chr53691760736917675+intron-Distal4.196273.30696K562EXOSC5
chr53692408736924161+intron-Distal4.863007.58902K562KHSRP
chr53687730136877370+intron-Proximal5.0969925.66103K562TIA1
chr53698640336986496+intron-Proximal4.554154.72162K562KHSRP
chr53687731136877339+intron-Proximal4.675237.49362HepG2TIAL1
chr53697214336972215+intron-Proximal4.681374.48002K562AQR
chr53696169636961773+intron-Proximal5.015997.69142K562KHSRP
chr53687729036877311+intron-Proximal5.637518.44039HepG2TIAL1
chr53700348237003546+intron-Proximal3.614144.23459K562PRPF8
chr53687729636877343+intron-Proximal3.045973.79487HepG2TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




No autoregularoty interactions between protein NIPBL and its RNA.



Diffrential Expression

  • The Knockdown/knockout assay for NIPBL is not available on ENCORE database.

  • 94 RBPs can affect the levels of NIPBL.  








The Knockdown/knockout RNA-Seq assay for NIPBL is not available on ENCORE database.





94 RBPs can affect the gene expression of NIPBL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NIPBLENSG00000164190.122075.505502387.94580-0.202302.511601.92740HepG2ACO1
NIPBLENSG00000164190.122884.502103284.28780-0.187302.234001.60490HepG2AUH
NIPBLENSG00000164190.12779.008601742.97100-1.1618016.2500013.81460HepG2BCCIP
NIPBLENSG00000164190.122645.053604150.26950-0.649906.126004.64750HepG2CCAR1
NIPBLENSG00000164190.122091.454202387.60330-0.191102.483101.84610HepG2CKAP4
NIPBLENSG00000164190.122595.160003140.53750-0.275201.993901.39950HepG2CPSF6
NIPBLENSG00000164190.121563.403901954.00220-0.321702.580801.60080HepG2YBX3
NIPBLENSG00000164190.121926.052602382.22040-0.306704.028703.27970HepG2CELF1
NIPBLENSG00000164190.122281.373402561.50430-0.167102.093701.43590HepG2DAZAP1
NIPBLENSG00000164190.121710.164302208.58880-0.369007.081105.84880HepG2DDX19B
NIPBLENSG00000164190.121466.421001956.66920-0.416105.832904.21230HepG2DDX1
NIPBLENSG00000164190.121405.626601907.78510-0.440704.464903.62460HepG2DDX21
NIPBLENSG00000164190.122078.036202767.08090-0.413103.445702.75720HepG2DDX3X
NIPBLENSG00000164190.121265.255401713.65020-0.437602.757701.98550HepG2DDX55
NIPBLENSG00000164190.122347.742002911.67270-0.310602.538501.56570HepG2DDX5
NIPBLENSG00000164190.121450.361101918.59970-0.403605.822404.83590HepG2DNAJC21
NIPBLENSG00000164190.121242.383901901.78010-0.6142014.1451012.78610HepG2DNAJC2
NIPBLENSG00000164190.121849.304202285.05450-0.305202.100401.57620HepG2EIF2S1
NIPBLENSG00000164190.121922.052202525.34870-0.393802.759202.12050HepG2EIF4A3
NIPBLENSG00000164190.122887.858802527.053200.192402.153201.39960HepG2EIF4G1
NIPBLENSG00000164190.121786.262202333.60630-0.385604.219803.18760HepG2EWSR1
NIPBLENSG00000164190.121152.994101614.10890-0.485403.189501.92180HepG2FAM120A
NIPBLENSG00000164190.121998.513801505.729200.408403.874502.95270HepG2FUBP3
NIPBLENSG00000164190.122874.456403560.09810-0.308602.098101.53610HepG2GPKOW
NIPBLENSG00000164190.121959.475902354.08010-0.264703.365802.34840HepG2HNRNPA2B1
NIPBLENSG00000164190.121597.877102154.57470-0.431204.535003.66260HepG2HNRNPC
NIPBLENSG00000164190.122472.794003397.46230-0.458304.670803.87380HepG2HNRNPLL
NIPBLENSG00000164190.121606.775902253.37030-0.487903.228402.20920HepG2HNRNPM
NIPBLENSG00000164190.121487.156102140.32690-0.5253011.5481010.38050HepG2HNRNPU
NIPBLENSG00000164190.121940.380302402.50120-0.308202.159501.55440HepG2IGF2BP2
NIPBLENSG00000164190.121782.433702186.26610-0.294605.309904.31980HepG2ILF2
NIPBLENSG00000164190.123401.825204380.63190-0.364802.342301.58250HepG2LARP4
NIPBLENSG00000164190.121514.821502107.24170-0.476204.665703.07450HepG2LIN28B
NIPBLENSG00000164190.121902.722802548.57190-0.421603.538502.79580HepG2MAGOH
NIPBLENSG00000164190.121851.947002643.52270-0.513403.444302.54260HepG2MSI2
NIPBLENSG00000164190.123660.181703012.460800.280902.230101.55610HepG2NSUN2
NIPBLENSG00000164190.122923.430402432.952300.264903.501902.64250HepG2PRPF4
NIPBLENSG00000164190.121999.656302373.10580-0.247003.219102.63790HepG2PTBP1
NIPBLENSG00000164190.121807.576402424.62470-0.423701.886301.38030HepG2PUF60
NIPBLENSG00000164190.122901.557402573.835500.172802.330701.77720HepG2PUM1
NIPBLENSG00000164190.121849.920402432.30350-0.394907.986707.03030HepG2PUS1
NIPBLENSG00000164190.123204.079802570.061900.318004.057303.32050HepG2QKI
NIPBLENSG00000164190.122709.205503151.71740-0.218302.438101.94310HepG2RBM22
NIPBLENSG00000164190.122808.871502332.522900.268002.447701.81010HepG2RBM25
NIPBLENSG00000164190.121897.967702419.36410-0.350202.409101.49070HepG2RBM27
NIPBLENSG00000164190.122842.642802459.793000.208602.541601.94710HepG2RECQL
NIPBLENSG00000164190.121334.572801757.51540-0.397202.197701.64300HepG2RPS19
NIPBLENSG00000164190.121582.687101906.03180-0.268203.681502.95740HepG2SAFB2
NIPBLENSG00000164190.121712.202302222.71490-0.376507.446006.46960HepG2SMN1
NIPBLENSG00000164190.124016.765203559.734200.174202.299001.82880HepG2SRFBP1
NIPBLENSG00000164190.123080.674902578.848200.256403.897103.35960HepG2SRSF1
NIPBLENSG00000164190.124977.401903618.347000.460003.566902.41710HepG2SRSF3
NIPBLENSG00000164190.122408.377502098.051100.198902.414601.89180HepG2SRSF9
NIPBLENSG00000164190.121553.411302107.32090-0.440002.891101.76360HepG2STIP1
NIPBLENSG00000164190.122783.474502318.036300.263903.077002.49070HepG2TAF15
NIPBLENSG00000164190.122420.314603311.33030-0.452205.061804.12460HepG2TARDBP
NIPBLENSG00000164190.121155.163302079.57520-0.8482019.2976018.19530HepG2TIAL1
NIPBLENSG00000164190.121391.061302098.32860-0.5931014.2164013.07960HepG2TRIM56
NIPBLENSG00000164190.124386.086402793.595700.6507010.039008.82690HepG2U2AF1
NIPBLENSG00000164190.12712.466601007.84030-0.500403.751402.86830HepG2UCHL5
NIPBLENSG00000164190.122349.234203131.15720-0.414509.321708.17160HepG2UPF1
NIPBLENSG00000164190.12985.588801562.38720-0.664704.462703.16910HepG2UPF2
NIPBLENSG00000164190.121768.514403023.01210-0.7734027.0600025.48840HepG2UTP3
NIPBLENSG00000164190.121575.539402169.76900-0.461702.868401.74720HepG2XPO5
NIPBLENSG00000164190.121088.875701679.36260-0.625106.040904.98290HepG2XRN2
NIPBLENSG00000164190.122125.355402401.07650-0.176002.192501.58410HepG2ZC3H8
NIPBLENSG00000164190.122889.943303443.67620-0.252904.943404.26520HepG2ZNF622
NIPBLENSG00000164190.124780.071306184.52450-0.371608.449107.52950K562AGGF1
NIPBLENSG00000164190.125241.040706435.28990-0.296202.778302.12330K562AKAP8L
NIPBLENSG00000164190.127468.732805073.408800.557808.602807.66060K562AQR
NIPBLENSG00000164190.125666.928106752.19070-0.252803.218802.22900K562ATP5C1
NIPBLENSG00000164190.122515.881503088.24990-0.295703.975002.34710K562BCCIP
NIPBLENSG00000164190.122568.452102984.30440-0.216502.824701.85410K562BCLAF1
NIPBLENSG00000164190.126157.530707390.80750-0.263402.851501.65360K562CCDC124
NIPBLENSG00000164190.125540.758706543.73080-0.240003.264402.05560K562CPEB4
NIPBLENSG00000164190.124001.902004829.47190-0.271202.929402.12310K562CPSF6
NIPBLENSG00000164190.121857.179902264.03940-0.285803.132902.00030K562CSTF2
NIPBLENSG00000164190.122757.847803366.15960-0.287602.794401.74680K562DDX3X
NIPBLENSG00000164190.122854.561703412.87890-0.257702.841901.51000K562DDX6
NIPBLENSG00000164190.126019.311106924.75850-0.202202.340301.54390K562DKC1
NIPBLENSG00000164190.123115.533603697.60060-0.247103.325001.98810K562EIF2S1
NIPBLENSG00000164190.123938.742002946.404000.418703.386402.23400K562EIF3D
NIPBLENSG00000164190.123051.770904839.74520-0.6653011.125609.30410K562FIP1L1
NIPBLENSG00000164190.123456.181202834.351900.286103.317801.83400K562FUS
NIPBLENSG00000164190.125501.092203858.304200.511704.028403.13560K562G3BP2
NIPBLENSG00000164190.123113.124305239.86940-0.7512016.2756014.39460K562GRSF1
NIPBLENSG00000164190.121964.763602798.88150-0.510505.294504.49340K562HNRNPC
NIPBLENSG00000164190.122542.595203980.60670-0.646707.752406.07080K562HNRNPM
NIPBLENSG00000164190.124691.729806561.88130-0.484006.313205.12350K562HSPD1
NIPBLENSG00000164190.123693.025204546.22590-0.299903.000002.12490K562MAGOH
NIPBLENSG00000164190.123724.939304500.80390-0.273002.605301.75980K562METAP2
NIPBLENSG00000164190.123872.325004638.04040-0.260304.548103.53350K562MTPAP
NIPBLENSG00000164190.124672.677605153.31930-0.141302.470101.76050K562NSUN2
NIPBLENSG00000164190.123077.450705493.84770-0.8361016.0354013.51760K562PPIG
NIPBLENSG00000164190.123475.877802677.847200.376203.569802.71640K562PRPF8
NIPBLENSG00000164190.121762.573302509.39640-0.509704.217303.06600K562PSIP1
NIPBLENSG00000164190.123076.686004416.89740-0.521708.639607.50800K562PTBP1
NIPBLENSG00000164190.127248.705308380.69480-0.209302.471901.56330K562PUM2
NIPBLENSG00000164190.123533.260504235.61190-0.261602.124001.39210K562RBM22
NIPBLENSG00000164190.124404.658105209.63740-0.242204.802603.61160K562SRPK2
NIPBLENSG00000164190.123415.073704189.86380-0.295002.240201.31190K562SRSF4
NIPBLENSG00000164190.123017.381404382.35350-0.538406.658205.51920K562TARDBP
NIPBLENSG00000164190.123587.055804227.23590-0.236902.278601.54230K562TIA1
NIPBLENSG00000164190.121765.559702413.67460-0.451103.981502.84470K562TIAL1
NIPBLENSG00000164190.122114.191202563.71120-0.278102.250401.41020K562TRIM56
NIPBLENSG00000164190.124910.667303739.202400.393103.134001.95790K562U2AF1
NIPBLENSG00000164190.124922.776803862.027000.350004.629103.59610K562U2AF2
NIPBLENSG00000164190.125405.584204861.966400.152802.064201.32600K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NIPBL is not available on ENCORE database.





16 RBPs can affect the splicing of NIPBL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENIPBLENSG00000164190.12chr5+369847773698640336975877369765043699572336995906-0.117000.000880.01884excludedK562SF3B4
SENIPBLENSG00000164190.12chr5+369847773698640336975877369765043699572336995906-0.122000.003250.08924excludedK562PRPF8
SENIPBLENSG00000164190.12chr5+370364803703658937027460370275143703870337038840-0.102000.001500.01984excludedHepG2U2AF2
SENIPBLENSG00000164190.12chr5+3705728737057434370524673705266837058992370592670.147000.000060.00664includedHepG2AKAP1
SENIPBLENSG00000164190.12chr5+369622243696237636961585369616853697097736971138-0.214000.000000.00002excludedK562AQR
SENIPBLENSG00000164190.12chr5+370572873705743437052467370526683705899237059267-0.121000.000000.00000excludedK562AQR
SENIPBLENSG00000164190.12chr5+370101883701032737008724370088253701478437014867-0.066000.000120.00204excludedK562AQR
SENIPBLENSG00000164190.12chr5+370572873705743437052467370526683705899237059267-0.182000.000320.05471excludedHepG2TIA1
SENIPBLENSG00000164190.12chr5+370572873705743437052467370526683705899237059267-0.056000.000490.00936excludedK562PUS1
SENIPBLENSG00000164190.12chr5+369847773698484036975877369765043699572336995906-0.334000.000520.03163excludedK562EFTUD2
SENIPBLENSG00000164190.12chr5+3705728737057434370524673705266837058992370592670.152000.000230.01367includedHepG2MATR3
SENIPBLENSG00000164190.12chr5+370572873705743437052467370526683705899237059267-0.089000.001190.02581excludedK562U2AF1
SENIPBLENSG00000164190.12chr5+3705728737057434370524673705266837058992370592670.089000.000970.06381includedHepG2HNRNPL
SENIPBLENSG00000164190.12chr5+370572873705743437052467370526683705899237059267-0.158000.000000.00001excludedK562U2AF2
SENIPBLENSG00000164190.12chr5+369622243696237636961585369616853697097736971138-0.087000.005770.08103excludedK562U2AF2
SENIPBLENSG00000164190.12chr5+370572873705743437052467370526683705899237059267-0.098000.000490.02199excludedK562HNRNPU
SENIPBLENSG00000164190.12chr5+370572873705743437052467370526683705899237059267-0.165000.001520.05375excludedHepG2HNRNPC
A3SSNIPBLENSG00000164190.12chr5+3700334237003449370033623700344937002698370028670.225000.000000.00000longerK562AQR
A3SSNIPBLENSG00000164190.12chr5+3702464137024821370246863702482137022345370224920.061000.000040.00035longerK562AQR
A3SSNIPBLENSG00000164190.12chr5+3706091137061087370609453706108737059205370592670.066000.000010.00014longerK562AQR
A3SSNIPBLENSG00000164190.12chr5+3703867537038840370387033703884037036480370365890.073000.000000.00000longerK562AQR
A3SSNIPBLENSG00000164190.12chr5+3700869337008825370087243700882537008109370081900.147000.000000.00000longerK562AQR
A3SSNIPBLENSG00000164190.12chr5+3702053437020775370205603702077537019412370195020.055000.000010.00013longerK562AQR
A5SSNIPBLENSG00000164190.12chr5+3701613937016366370161393701627237017120370172640.081000.000000.00015longerK562AQR
MXENIPBLENSG00000164190.12chr5+36984777369864033699572336995906369758773697650437000474370006720.148000.000570.041471includedK562LARP4
MXENIPBLENSG00000164190.12chr5+36984777369864033699572336995906369758773697650437000474370006720.185000.000030.001391includedK562DROSHA
MXENIPBLENSG00000164190.12chr5+37008693370088253701018837010327370081093700819037014784370148670.184000.000000.000001includedK562AQR
MXENIPBLENSG00000164190.12chr5+3700645837006690370074243700757637003362370034493700810937008190-0.123000.004030.030002includedK562AQR
MXENIPBLENSG00000164190.12chr5+3700645837006690370073873700757637003362370034493700810937008190-0.119000.005960.041672includedK562AQR
MXENIPBLENSG00000164190.12chr5+36984777369864033699572336995906369758773697650437000474370006720.196000.000010.000681includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NIPBL is not avaliable on ENCORE database.