LSG1

General Information

Gene Name       : LSG1
Gene ID             : ENSG00000041802.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: LSG1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LSG1ENSG00000041802.1048.4844.8046.64ENCSR000AEF
HepG2LSG1ENSG00000041802.1025.1429.4327.29ENCSR985KAT
K562LSG1ENSG00000041802.1035.6937.3036.49ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LSG1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LSG1 RNA is bound by 9 proteins.  







eCLIP assay for LSG1 is not avaliable on ENCORE database.





9 proteins are bound to LSG1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3194361999194362074-3'-UTR,intron-Distal4.7797610.60336K562UPF1
chr3194362187194362319-3'-UTR,intron-Distal4.4867613.57997K562UPF1
chr3194361756194361819-3'-UTR,intron-Distal4.331444.01886HepG2LIN28B
chr3194379762194379856-3'-UTR,CDS,intron-Distal,intron-Proximal3.752115.14848K562ZNF622
chr3194361758194361826-3'-UTR,intron-Distal5.9270117.08237K562LIN28B
chr3194362172194362282-3'-UTR,intron-Distal3.321364.50192K562FAM120A
chr3194362221194362365-3'-UTR,intron-Distal4.456784.68979HepG2UPF1
chr3194392842194392912-5'-UTR,CDS,intron-Distal,intron-Proximal5.1746010.52516K562DDX3X
chr3194373459194373550-CDS,intron-Distal,intron-Proximal3.868617.10975K562UCHL5
chr3194373471194373534-CDS,intron-Distal4.187843.71570HepG2BCLAF1
chr3194366892194366967-CDS,intron-Distal,intron-Proximal3.075724.24993HepG2PPIG
chr3194392794194392842-CDS,intron-Distal,intron-Proximal3.891676.02664K562DDX3X
chr3194392796194392866-CDS,intron-Distal,intron-Proximal3.483403.95301K562ZNF622
chr3194373451194373570-CDS,intron-Distal,intron-Proximal3.209684.09398HepG2GRWD1
chr3194373476194373566-CDS,intron-Distal,intron-Proximal4.180725.04143K562GRWD1
chr3194373637194373730-CDS,intron-Distal,intron-Proximal3.875514.74268K562UCHL5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LSG1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LSG1 is not available on ENCORE database.

  • 93 RBPs can affect the levels of LSG1.  








The Knockdown/knockout RNA-Seq assay for LSG1 is not available on ENCORE database.





93 RBPs can affect the gene expression of LSG1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LSG1ENSG00000041802.6653.08910463.777300.493705.418204.62320HepG2ACO1
LSG1ENSG00000041802.6998.79550450.307301.1492013.3609012.28300HepG2AKAP1
LSG1ENSG00000041802.6491.03040372.587800.398101.987301.31740HepG2ASCC1
LSG1ENSG00000041802.6669.94240807.78430-0.269902.100401.48700HepG2AUH
LSG1ENSG00000041802.6880.81000644.364700.450903.599302.92650HepG2BOP1
LSG1ENSG00000041802.6443.39710225.264600.976905.305102.62410HepG2CDC40
LSG1ENSG00000041802.6495.83930353.985200.486102.767301.99490HepG2CIRBP
LSG1ENSG00000041802.6976.85970463.695101.0749028.0488026.42780HepG2CKAP4
LSG1ENSG00000041802.6349.44140591.56990-0.759506.544305.51980HepG2CPSF6
LSG1ENSG00000041802.6528.86210708.33010-0.421504.429903.52690HepG2DAZAP1
LSG1ENSG00000041802.6529.74480428.936100.304402.283601.52100HepG2DDX19B
LSG1ENSG00000041802.6619.11780401.137300.626005.245104.34020HepG2DDX21
LSG1ENSG00000041802.6722.18690431.352400.743406.335605.42710HepG2DDX3X
LSG1ENSG00000041802.6208.01900382.68800-0.879508.483207.30570HepG2DNAJC21
LSG1ENSG00000041802.6512.47620357.215800.520603.019402.05730HepG2EEF2
LSG1ENSG00000041802.6497.87940297.794600.741405.798104.18750HepG2EFTUD2
LSG1ENSG00000041802.6395.50670289.980700.447602.219801.40140HepG2EIF3D
LSG1ENSG00000041802.6651.88140393.644000.727605.523904.62150HepG2EIF4A3
LSG1ENSG00000041802.6377.53930669.45020-0.826308.306906.93040HepG2EIF4G2
LSG1ENSG00000041802.61332.44470927.427600.522708.614707.65450HepG2ETF1
LSG1ENSG00000041802.6589.35030453.209800.378802.494601.70080HepG2EWSR1
LSG1ENSG00000041802.6726.07060521.763000.476602.898102.11000HepG2FIP1L1
LSG1ENSG00000041802.6343.62050245.585800.484502.443701.70460HepG2FUBP3
LSG1ENSG00000041802.6581.77300397.197400.550503.574802.79490HepG2FXR1
LSG1ENSG00000041802.6509.25570368.444500.466802.570701.92860HepG2G3BP1
LSG1ENSG00000041802.6570.23870734.28470-0.364803.426102.63390HepG2HNRNPF
LSG1ENSG00000041802.6565.03930373.116700.598604.275003.42250HepG2HNRNPK
LSG1ENSG00000041802.6453.95220645.21920-0.507205.506104.58340HepG2HNRNPL
LSG1ENSG00000041802.6469.15260639.97590-0.448002.680102.05880HepG2HNRNPLL
LSG1ENSG00000041802.6477.59050360.104400.407302.698001.75760HepG2HNRNPM
LSG1ENSG00000041802.6518.38100426.914100.280001.830701.32790HepG2HNRNPU
LSG1ENSG00000041802.6576.85990723.05720-0.325901.970901.35170HepG2IGF2BP1
LSG1ENSG00000041802.6568.21130374.510800.601304.149903.33790HepG2IGF2BP2
LSG1ENSG00000041802.6576.95770351.482600.714902.312601.42100HepG2IGF2BP3
LSG1ENSG00000041802.6521.03850380.694300.452702.658701.54660HepG2LARP7
LSG1ENSG00000041802.6903.00900397.336101.1843015.7491014.24620HepG2MAGOH
LSG1ENSG00000041802.6897.15870399.555601.1669013.8467012.51360HepG2MATR3
LSG1ENSG00000041802.6444.92080303.491700.551802.285601.32760HepG2METAP2
LSG1ENSG00000041802.6663.25610422.456100.650706.573905.37870HepG2MSI2
LSG1ENSG00000041802.6432.17710652.64430-0.594702.869101.88150HepG2MTPAP
LSG1ENSG00000041802.6747.04090408.963800.869108.302007.23350HepG2NCBP2
LSG1ENSG00000041802.6404.14450567.44510-0.489602.957202.18440HepG2NSUN2
LSG1ENSG00000041802.6528.57710364.192500.537303.319602.53360HepG2PABPC4
LSG1ENSG00000041802.6569.52070377.118100.594606.154605.30430HepG2PCBP1
LSG1ENSG00000041802.6292.69560380.77190-0.379502.220901.55350HepG2PPIL4
LSG1ENSG00000041802.6670.48310383.722100.8050011.2395010.28220HepG2PTBP1
LSG1ENSG00000041802.61072.53220711.780100.5914011.5426010.50500HepG2PUM1
LSG1ENSG00000041802.6580.39930472.390000.297002.211801.64660HepG2PUS1
LSG1ENSG00000041802.6568.70340415.601100.452403.270002.59910HepG2QKI
LSG1ENSG00000041802.61245.48930775.161300.6840011.7588010.84450HepG2RBM22
LSG1ENSG00000041802.6627.85450459.065200.451602.561601.61040HepG2RBM27
LSG1ENSG00000041802.6530.66600372.782200.509402.731401.67930HepG2RCC2
LSG1ENSG00000041802.6678.26720427.053900.667307.569106.75290HepG2NELFE
LSG1ENSG00000041802.6438.43300282.164100.635704.700503.92280HepG2RPS19
LSG1ENSG00000041802.6624.19710423.363000.560003.765702.83660HepG2RPS2
LSG1ENSG00000041802.6586.68420432.179800.440902.424001.42200HepG2RPS5
LSG1ENSG00000041802.6697.37390440.483500.662704.836103.82890HepG2RRP9
LSG1ENSG00000041802.61761.78930520.235101.7597029.9888027.73720HepG2SF3A3
LSG1ENSG00000041802.6791.40100633.462400.321101.916801.32280HepG2SF3B1
LSG1ENSG00000041802.6831.85650399.521501.0580019.9911018.63800HepG2SF3B4
LSG1ENSG00000041802.6582.48040443.347500.393703.524002.81230HepG2SMN1
LSG1ENSG00000041802.6983.31450417.006901.2375029.4556028.27480HepG2SRSF1
LSG1ENSG00000041802.6558.88810721.42280-0.368303.519102.74800HepG2SRSF7
LSG1ENSG00000041802.6470.18500304.365900.627303.741902.44410HepG2STIP1
LSG1ENSG00000041802.6979.09860752.904100.378904.678203.90690HepG2SUCLG1
LSG1ENSG00000041802.6562.09450377.758300.573203.185401.75570HepG2SUGP2
LSG1ENSG00000041802.6453.17050623.72020-0.460802.989902.23970HepG2TARDBP
LSG1ENSG00000041802.6688.09400446.434100.624105.352804.49490HepG2U2AF1
LSG1ENSG00000041802.61101.57440445.434601.3062037.3167035.49660HepG2UTP3
LSG1ENSG00000041802.6633.64710458.235900.467502.317201.34890HepG2XRCC6
LSG1ENSG00000041802.6739.30550507.418100.542907.396806.61410HepG2ZNF622
LSG1ENSG00000041802.61079.64190718.417000.587606.465504.60650K562AARS
LSG1ENSG00000041802.63847.931301611.821601.2553032.6509030.83760K562AQR
LSG1ENSG00000041802.6826.371801060.63110-0.360103.262902.21810K562BCLAF1
LSG1ENSG00000041802.6669.09540967.65500-0.532305.617604.50770K562CPSF6
LSG1ENSG00000041802.6993.095101231.99250-0.311003.178501.87410K562DDX21
LSG1ENSG00000041802.62068.115901438.816900.523304.227003.44470K562DDX47
LSG1ENSG00000041802.61535.93760893.673300.7812010.675108.77210K562EFTUD2
LSG1ENSG00000041802.6702.45680480.862700.546702.397001.46680K562EIF3A
LSG1ENSG00000041802.61416.10900956.906900.565404.479203.12540K562EIF3D
LSG1ENSG00000041802.61129.69450751.391500.588208.322706.94920K562EIF3G
LSG1ENSG00000041802.6918.26430611.781500.585806.006404.80670K562EIF4A3
LSG1ENSG00000041802.61084.134701391.04180-0.359602.939002.06440K562FIP1L1
LSG1ENSG00000041802.61641.20060636.228601.3670046.7337044.42750K562FXR1
LSG1ENSG00000041802.61769.217902137.25450-0.272602.184901.50840K562GRSF1
LSG1ENSG00000041802.6462.16500802.64750-0.796403.563002.12250K562HNRNPA2B1
LSG1ENSG00000041802.61035.81660764.298600.438502.627701.42760K562HNRNPK
LSG1ENSG00000041802.61244.332501885.97430-0.599907.431406.14310K562HSPD1
LSG1ENSG00000041802.61453.09830804.264800.853306.066104.80350K562MAGOH
LSG1ENSG00000041802.6890.791601220.85560-0.454707.834906.66670K562NSUN2
LSG1ENSG00000041802.6425.37800702.46970-0.723702.931301.90290K562PABPN1
LSG1ENSG00000041802.61227.67280715.585200.7786010.634308.64990K562PCBP2
LSG1ENSG00000041802.61177.849301579.09020-0.422903.811902.82710K562PPIG
LSG1ENSG00000041802.61852.07220869.645701.0905019.9731017.95180K562PRPF8
LSG1ENSG00000041802.6525.93040705.04210-0.422802.928001.99220K562PSIP1
LSG1ENSG00000041802.61367.95950781.398300.8078014.0243012.59070K562PTBP1
LSG1ENSG00000041802.63193.945302179.974600.550905.613504.45420K562PUF60
LSG1ENSG00000041802.61039.63490749.233600.472504.254303.18490K562RBM22
LSG1ENSG00000041802.61011.01540788.456500.358602.436801.42340K562NELFE
LSG1ENSG00000041802.61383.39010885.870800.642905.991504.78480K562RPS19
LSG1ENSG00000041802.6831.32920585.193600.506405.205404.01060K562SF3B4
LSG1ENSG00000041802.61017.55650766.037800.409503.706802.89370K562SRSF1
LSG1ENSG00000041802.6822.912301099.43490-0.418004.961703.37930K562SRSF7
LSG1ENSG00000041802.6541.34180775.07960-0.517805.300103.43510K562SSB
LSG1ENSG00000041802.61514.18250880.189400.7826014.1847012.33150K562SYNCRIP
LSG1ENSG00000041802.6412.77960678.15370-0.716205.942204.51890K562TIAL1
LSG1ENSG00000041802.6496.55240720.25660-0.536604.146702.94120K562TRIM56
LSG1ENSG00000041802.6865.20360563.407600.618807.411106.10170K562U2AF2
LSG1ENSG00000041802.6617.53450891.19730-0.529204.159002.88650K562UCHL5
LSG1ENSG00000041802.6750.186101107.66630-0.562205.240904.01600K562WDR3
LSG1ENSG00000041802.61333.30620701.107400.927205.821803.32090K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LSG1 is not available on ENCORE database.





1 RBPs can affect the splicing of LSG1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELSG1ENSG00000041802.6chr3-194380801194380862194379834194379862194386285194386372-0.137000.000000.00000excludedK562AQR
A3SSLSG1ENSG00000041802.6chr3-1943668921943670691943668921943669721943694091943697480.167000.000000.00000longerK562AQR
A3SSLSG1ENSG00000041802.6chr3-1943871801943873961943871801943873011943907371943908640.132000.000000.00000longerK562AQR
A3SSLSG1ENSG00000041802.6chr3-1943718431943719871943718431943719451943734571943738310.069000.001920.01243longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LSG1 is not avaliable on ENCORE database.