CDKL3

General Information

Gene Name : CDKL3
Gene ID : ENSG00000006837.11
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CDKL3)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CDKL3	ENSG00000006837.11	1.35	0.68	1.02	ENCSR000AEF
HepG2	CDKL3	ENSG00000006837.11	0.89	2.26	1.57	ENCSR985KAT
K562	CDKL3	ENSG00000006837.11	1.70	1.00	1.35	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CDKL3 is not avaliable on ENCORE database.

Proteins bound to RNA

CDKL3 RNA is bound by 12 proteins.

eCLIP assay for CDKL3 is not avaliable on ENCORE database.

12 proteins are bound to CDKL3 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr5	133541697	133541823	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.01820	3.35081	HepG2	G3BP1
chr5	133541543	133541605	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.33466	3.76553	K562	PRPF8
chr5	133541701	133541823	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.83658	5.37552	K562	PUM1
chr5	133561403	133561458	-	CDS,intron-Distal	3.56546	7.02084	HepG2	PRPF8
chr5	133561454	133561575	-	5'-UTR,CDS,intron-Distal	3.55443	14.36757	K562	UCHL5
chr5	133552021	133552071	-	intron-Distal	3.25873	4.41834	HepG2	HNRNPC
chr5	133561542	133561637	-	5'-UTR,CDS,intron-Distal	3.31489	16.42912	K562	DDX3X
chr5	133561492	133561565	-	5'-UTR,CDS,intron-Distal	3.62385	10.87852	HepG2	GRWD1
chr5	133561422	133561647	-	5'-UTR,CDS,intron-Distal	3.40410	8.18487	HepG2	SRSF1
chr5	133561637	133561758	-	5'-UTR,intron-Distal	4.03092	34.01079	K562	DDX3X
chr5	133561504	133561549	-	CDS,intron-Distal	4.04663	6.70275	K562	RBM15
chr5	133561406	133561458	-	CDS,intron-Distal	5.10331	6.75320	K562	AQR
chr5	133561652	133561753	-	5'-UTR,intron-Distal	4.15370	5.44438	HepG2	DDX3X
chr5	133561457	133561562	-	5'-UTR,CDS,intron-Distal	3.67690	11.67526	K562	GEMIN5
chr5	133650478	133650619	-	intron-Distal	3.69800	3.27276	HepG2	HNRNPL
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for CDKL3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CDKL3 is not available on ENCORE database.
9 RBPs can affect the levels of CDKL3.

The Knockdown/knockout RNA-Seq assay for CDKL3 is not available on ENCORE database.

9 RBPs can affect the gene expression of CDKL3 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CDKL3	ENSG00000006837.7	55.86730	28.69920	0.96090	1.88900	1.38640	HepG2	BOP1
CDKL3	ENSG00000006837.7	31.93390	57.44110	-0.84700	1.97350	1.49740	HepG2	PTBP1
CDKL3	ENSG00000006837.7	68.36300	30.35720	1.17110	2.34040	1.42940	HepG2	SRSF3
CDKL3	ENSG00000006837.7	61.77710	25.89500	1.25430	2.69730	1.49390	K562	ABCF1
CDKL3	ENSG00000006837.7	103.52570	33.32780	1.63510	5.57180	4.78950	K562	AQR
CDKL3	ENSG00000006837.7	59.74220	23.18020	1.36580	3.08890	2.18010	K562	FMR1
CDKL3	ENSG00000006837.7	53.11340	23.81120	1.15730	2.14160	1.40890	K562	PCBP3
CDKL3	ENSG00000006837.7	97.12690	44.66560	1.12060	3.60240	2.67440	K562	PUF60
CDKL3	ENSG00000006837.7	45.66180	21.33850	1.09740	2.16170	1.43290	K562	SF3A3
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CDKL3 is not available on ENCORE database.

1 RBPs can affect the splicing of CDKL3 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP	Bound by RBP
MXE	CDKL3	ENSG00000006837.7	chr5	-	133644264	133644418	133647982	133648071	133643828	133644157	133655048	133655188	0.33400	0.00108	0.00867	1included	HepG2	U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CDKL3

General Information

Functions

Localization

Domains (AlphaFold: CDKL3)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CDKL3 is not avaliable on ENCORE database.

12 proteins are bound to CDKL3 RNA:

eCLIP assay for CDKL3 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CDKL3 is not available on ENCORE database.

9 RBPs can affect the gene expression of CDKL3 :

The Knockdown/knockout RNA-Seq assay for CDKL3 is not available on ENCORE database.

1 RBPs can affect the splicing of CDKL3 :

The Knockdown/knockout RNA-Seq assay for CDKL3 is not avaliable on ENCORE database.