CFH

General Information

Gene Name       : CFH
Gene ID             : ENSG00000000971.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CFH)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CFHENSG00000000971.150.000.000.00ENCSR000AEF
HepG2CFHENSG00000000971.150.000.000.00ENCSR985KAT
K562CFHENSG00000000971.1530.0232.5231.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CFH is not avaliable on ENCORE database.



Proteins bound to RNA
  • CFH RNA is bound by 12 proteins.  







eCLIP assay for CFH is not avaliable on ENCORE database.





12 proteins are bound to CFH RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1196670558196670653+3'-UTR,intron-Distal5.154215.61461HepG2SUB1
chr1196654352196654368+CDS,intron-Proximal4.515483.60906K562SND1
chr1196648844196648923+CDS4.1624910.46407K562SND1
chr1196654193196654254+CDS,intron-Proximal3.398433.90826K562ZNF622
chr1196682892196682936+CDS3.336113.20659K562SND1
chr1196645143196645194+CDS4.843436.53278K562SND1
chr1196654325196654422+CDS,intron-Proximal3.356867.41728K562PRPF8
chr1196706068196706121+CDS3.248653.02345K562ZNF622
chr1196658548196658625+CDS,intron-Proximal4.015278.01541K562SND1
chr1196654283196654352+CDS3.113717.67013K562SND1
chr1196654210196654283+CDS3.640758.56125K562SND1
chr1196642168196642191+CDS4.419434.24959K562SND1
chr1196684727196684776+CDS4.484205.02285K562SND1
chr1196642107196642210+CDS,intron-Proximal3.329537.29897K562DDX24
chr1196646606196646747+CDS,intron-Distal4.4039714.09740K562SND1
chr1196648769196648811+CDS4.403974.89631K562SND1
chr1196643056196643093+CDS,intron-Proximal3.586493.79230K562SND1
chr1196642970196643019+CDS,intron-Proximal3.776726.67591K562SF3B4
chr1196642227196642329+CDS,intron-Proximal6.333569.67979K562EFTUD2
chr1196658654196658744+CDS4.5190914.37233K562SND1
chr1196621253196621306+CDS,intron-Proximal3.831785.77244K562UCHL5
chr1196709802196709919+CDS3.794785.42720K562UCHL5
chr1196654193196654210+CDS,intron-Proximal4.782655.61687K562SND1
chr1196642112196642168+CDS4.011646.16416K562SND1
chr1196694366196694406+CDS4.143163.83751K562SND1
chr1196642237196642291+CDS4.341008.87572K562SND1
chr1196642987196643056+CDS3.340618.11686K562SND1
chr1196711018196711061+CDS3.139953.20659K562SND1
chr1196654564196654679+intron-Distal4.092084.43126K562KHDRBS1
chr1196646825196646888+intron-Distal,intron-Proximal4.525553.61992K562RBM22
chr1196710814196710993+intron-Distal,intron-Proximal4.610989.63457K562KHSRP
chr1196662051196662111+intron-Distal5.9604712.39591K562PTBP1
chr1196661963196662007+intron-Distal5.261577.41017K562PTBP1
chr1196621353196621465+intron-Distal,intron-Proximal3.148103.57533K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CFH is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CFH is not available on ENCORE database.

  • 77 RBPs can affect the levels of CFH.  








The Knockdown/knockout RNA-Seq assay for CFH is not available on ENCORE database.





77 RBPs can affect the gene expression of CFH :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CFHENSG00000000971.1116.521400.0000099999.999903.426502.38310HepG2ABCF1
CFHENSG00000000971.1131.154000.0000099999.999907.495006.66400HepG2AKAP1
CFHENSG00000000971.1118.946800.0000099999.999905.814904.85110HepG2CPSF6
CFHENSG00000000971.1120.916600.0000099999.999905.568904.61220HepG2HNRNPC
CFHENSG00000000971.11369.21780753.28190-1.028705.254402.89420K562ADAR
CFHENSG00000000971.112273.387402682.80210-0.238902.911202.33070K562AGGF1
CFHENSG00000000971.112168.279102791.58810-0.364503.495302.75710K562AKAP8L
CFHENSG00000000971.11609.674702509.96690-2.0416066.1737063.65210K562AQR
CFHENSG00000000971.11958.660601412.17870-0.5588010.224208.36390K562BCLAF1
CFHENSG00000000971.111969.459801331.263600.564904.442003.32670K562BOP1
CFHENSG00000000971.111248.003902391.19110-0.938107.856406.01670K562CNOT7
CFHENSG00000000971.112825.725802234.685800.338405.167003.62150K562CPEB4
CFHENSG00000000971.11781.910601071.34800-0.454405.250303.73000K562CSTF2
CFHENSG00000000971.112551.938804108.78010-0.6871016.1011013.91380K562CELF1
CFHENSG00000000971.111167.686501433.88200-0.296302.887401.54230K562DDX6
CFHENSG00000000971.112261.064703003.88070-0.409806.700405.24390K562DKC1
CFHENSG00000000971.11381.06270840.78230-1.141708.571005.65580K562DNAJC2
CFHENSG00000000971.11879.935101176.61060-0.419203.193402.20710K562EFTUD2
CFHENSG00000000971.116330.278901532.309702.04650159.54970156.51650K562EIF2S2
CFHENSG00000000971.111852.532801259.891700.556103.698002.48610K562EIF3D
CFHENSG00000000971.111051.401401477.56800-0.490905.176504.05290K562EIF4A3
CFHENSG00000000971.111080.677801330.64540-0.300202.825001.65420K562EIF4B
CFHENSG00000000971.112452.992603341.36900-0.445908.853007.20910K562EIF4G2
CFHENSG00000000971.11971.665401289.77640-0.408604.212702.57160K562EWSR1
CFHENSG00000000971.11592.482101063.22150-0.8436012.289209.68680K562EXOSC5
CFHENSG00000000971.111695.343201047.300000.694807.089804.50690K562FAM120A
CFHENSG00000000971.111047.419901429.21620-0.448404.175903.12120K562FIP1L1
CFHENSG00000000971.111912.616301261.999800.599704.779703.22940K562FKBP4
CFHENSG00000000971.112015.652501440.169500.484904.262503.20150K562FMR1
CFHENSG00000000971.111169.916301536.61130-0.393305.035504.25360K562FXR1
CFHENSG00000000971.112299.670701703.483800.432802.853302.13300K562G3BP2
CFHENSG00000000971.11908.333701593.01090-0.8105017.3102014.90880K562GLRX3
CFHENSG00000000971.11925.700801770.37850-0.9354019.5729017.09960K562HNRNPA1
CFHENSG00000000971.11952.090001960.49160-1.0420029.6785027.06190K562HNRNPU
CFHENSG00000000971.113532.296901937.629400.8662016.3252014.49670K562HSPD1
CFHENSG00000000971.111741.679502354.69250-0.435102.836101.79550K562IGF2BP2
CFHENSG00000000971.111980.813402475.89630-0.321902.083101.34860K562MAGOH
CFHENSG00000000971.111387.165802471.05700-0.833007.951606.28580K562MATR3
CFHENSG00000000971.114182.781103318.792400.333703.777302.68740K562MBNL1
CFHENSG00000000971.11828.400401319.30930-0.671403.640802.62810K562METAP2
CFHENSG00000000971.111185.607101674.85810-0.498409.345907.94940K562MTPAP
CFHENSG00000000971.112054.608201475.418700.477606.678104.80090K562NCBP2
CFHENSG00000000971.11954.245101860.83460-0.9635039.6713037.41860K562NSUN2
CFHENSG00000000971.111610.181402297.23590-0.512703.162201.83060K562PABPC1
CFHENSG00000000971.111677.237302203.15500-0.393502.290101.40530K562PCBP2
CFHENSG00000000971.11982.436901352.41830-0.461103.618902.66690K562PCBP3
CFHENSG00000000971.11791.134101037.39990-0.391003.155202.29580K562POLR2G
CFHENSG00000000971.112256.033301444.935700.642703.446501.35170K562PRPF6
CFHENSG00000000971.112651.006703645.64420-0.459606.213404.99360K562PUF60
CFHENSG00000000971.115893.591803799.380400.6333017.7909015.45650K562PUM2
CFHENSG00000000971.112752.728101625.474300.759905.699803.55800K562RAVER1
CFHENSG00000000971.112166.627002697.46460-0.316203.775503.09880K562RBM15
CFHENSG00000000971.111291.698602307.14890-0.836808.245706.68680K562RBM22
CFHENSG00000000971.113309.709402427.751000.447004.263502.87310K562NELFE
CFHENSG00000000971.11793.781701170.76690-0.560603.680102.13050K562RRP9
CFHENSG00000000971.111061.577901814.40500-0.773308.608505.53740K562SAFB2
CFHENSG00000000971.11557.20900924.19480-0.730008.423406.58430K562SAFB
CFHENSG00000000971.111447.636002178.12210-0.589403.736801.90040K562SBDS
CFHENSG00000000971.11713.92280955.57860-0.420603.206901.64170K562SDAD1
CFHENSG00000000971.11445.25010979.83480-1.1379011.145408.41920K562SERBP1
CFHENSG00000000971.111489.634301836.29250-0.301803.550802.63490K562SF3A3
CFHENSG00000000971.111025.364901771.98260-0.7892015.7123013.54870K562SF3B4
CFHENSG00000000971.11574.95630812.46500-0.498904.125402.56090K562SLBP
CFHENSG00000000971.112149.207301387.640400.631106.389803.67230K562SND1
CFHENSG00000000971.111482.292702357.95660-0.669706.817505.71750K562SRSF1
CFHENSG00000000971.11749.43900935.30280-0.319602.731301.57370K562SRSF7
CFHENSG00000000971.112604.020201875.133700.473605.135003.24720K562SSRP1
CFHENSG00000000971.112639.396203180.83980-0.269202.980501.41430K562SUCLG1
CFHENSG00000000971.11663.868901108.71070-0.739907.257705.55700K562SUPV3L1
CFHENSG00000000971.11809.737001254.75090-0.631903.608202.53550K562TIAL1
CFHENSG00000000971.11913.019801332.48920-0.545402.627401.71120K562TRIM56
CFHENSG00000000971.111243.662201651.97060-0.409602.932201.80120K562U2AF1
CFHENSG00000000971.112422.165601973.088900.295704.585603.68490K562UPF1
CFHENSG00000000971.112141.918401565.499800.452203.774402.35970K562UTP3
CFHENSG00000000971.111052.613701688.29910-0.6816010.736108.96350K562WDR3
CFHENSG00000000971.11787.622601194.71810-0.601105.806803.83430K562XRN2
CFHENSG00000000971.111987.672602827.38390-0.508406.464505.05940K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CFH is not available on ENCORE database.





12 RBPs can affect the splicing of CFH :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECFHENSG00000000971.11chr1+196694250196694427196684722196684899196695599196695782-0.078000.006840.09677excludedK562SRSF1
SECFHENSG00000000971.11chr1+1966445791966446591966429861966430921966451181966451950.117000.000000.00084includedK562MTPAP
SECFHENSG00000000971.11chr1+1966445791966446591966429861966430921966451181966451950.057000.001320.07838includedK562HNRNPL
SECFHENSG00000000971.11chr1+1966445791966446591966429861966430921966451181966451950.058000.000040.00283includedK562HNRNPU
A5SSCFHENSG00000000971.11chr1+196621185196621305196621185196621219196642107196642293-0.052000.006470.08908shorterK562AQR
RICFHENSG00000000971.11chr1+196709748196711181196709748196709922196711004196711181-0.140000.004380.02776excludedK562PUS1
RICFHENSG00000000971.11chr1+196709748196711181196709748196709922196711004196711181-0.269000.000030.00940excludedK562SSB
RICFHENSG00000000971.11chr1+196709748196711181196709748196709922196711004196711181-0.168000.002910.03306excludedK562AGGF1
RICFHENSG00000000971.11chr1+196709748196711181196709748196709922196711004196711181-0.152000.007840.06357excludedK562AKAP8L
RICFHENSG00000000971.11chr1+196709748196711181196709748196709922196711004196711181-0.292000.000030.00396excludedK562EIF3G
RICFHENSG00000000971.11chr1+196709748196711181196709748196709922196711004196711181-0.186000.000010.00060excludedK562TARDBP
RICFHENSG00000000971.11chr1+196709748196711181196709748196709922196711004196711181-0.130000.007340.09499excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CFH is not avaliable on ENCORE database.