PPP5C

General Information

Gene Name       : PPP5C
Gene ID             : ENSG00000011485.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PPP5C)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPP5CENSG00000011485.14102.3592.8597.60ENCSR000AEF
HepG2PPP5CENSG00000011485.1496.9674.9685.96ENCSR985KAT
K562PPP5CENSG00000011485.14118.07111.50114.78ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPP5C is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPP5C RNA is bound by 37 proteins.  







eCLIP assay for PPP5C is not avaliable on ENCORE database.





37 proteins are bound to PPP5C RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194689374046893805+3'-UTR,intron-Distal3.531345.77770K562PUM1
chr194689373046893806+3'-UTR,intron-Distal3.491713.60227HepG2TIAL1
chr194689381046893976+3'-UTR,intron-Distal5.9681223.35679K562UPF1
chr194689380746893867+3'-UTR,intron-Distal4.043243.34382K562APOBEC3C
chr194689388746893933+3'-UTR,intron-Distal5.478409.39648K562PABPC4
chr194689373946893845+3'-UTR,intron-Distal3.7369515.48628HepG2DDX55
chr194689383846893911+3'-UTR,intron-Distal3.209393.62686HepG2LSM11
chr194689383046893877+3'-UTR,intron-Distal4.250958.69556K562DDX6
chr194689383046893891+3'-UTR,intron-Distal4.226975.17223K562ZC3H11A
chr194689372546893755+3'-UTR,intron-Distal6.76976400.00000K562PUM2
chr194689374246893811+3'-UTR,intron-Distal3.641449.88743HepG2SUB1
chr194689373446893798+3'-UTR,intron-Distal3.489553.44343HepG2AKAP1
chr194689374846893830+3'-UTR,intron-Distal4.0391916.29776K562ZC3H11A
chr194689381146893932+3'-UTR,intron-Distal3.600979.96417K562DDX55
chr194689381546893882+3'-UTR,intron-Distal4.375183.72779HepG2LARP4
chr194689373246893814+3'-UTR,intron-Distal5.4111931.89606K562DDX6
chr194689372946893802+3'-UTR,intron-Distal3.590386.19872K562APOBEC3C
chr194689372946893931+3'-UTR,intron-Distal4.264545.56088HepG2PABPN1
chr194689372746893835+3'-UTR,intron-Distal5.5479347.64155K562PABPC4
chr194689372946893805+3'-UTR,intron-Distal3.539995.39571HepG2LARP4
chr194689373346893810+3'-UTR,intron-Distal4.5152116.94237K562UPF1
chr194689372946893811+3'-UTR,intron-Distal4.9506632.33226K562DDX55
chr194689375546893801+3'-UTR,intron-Distal6.29008400.00000K562PUM2
chr194689372746893964+3'-UTR,intron-Distal6.9361135.38470HepG2UPF1
chr194685715846857242+5'-UTR,CDS4.141417.85254K562FMR1
chr194685700446857083+5'-UTR,CDS,intron-Proximal3.282483.49777K562ZNF800
chr194685034746850460+5'-UTR,CDS3.020998.85325K562ZNF622
chr194685700346857154+5'-UTR,CDS,intron-Proximal3.8092511.16233K562YBX3
chr194685046846850533+5'-UTR,CDS,intron-Proximal5.044946.35567HepG2PRPF8
chr194685035646850475+5'-UTR,CDS,intron-Proximal4.5030610.59420HepG2GRWD1
chr194685028046850470+5'-UTR,CDS3.418588.86075K562DDX3X
chr194685700446857245+5'-UTR,CDS,intron-Proximal3.091703.16615HepG2G3BP1
chr194685709246857155+5'-UTR,CDS4.332514.69071HepG2GRWD1
chr194685700246857092+5'-UTR,CDS,intron-Proximal5.381998.99884HepG2GRWD1
chr194685716346857240+5'-UTR,CDS3.030706.19730K562ZNF622
chr194687885446878921+CDS,intron-Proximal3.045525.12559K562ZNF800
chr194688807346888156+CDS3.975663.56019HepG2GRWD1
chr194689069346890748+CDS,intron-Proximal5.1888414.11848HepG2PRPF8
chr194687890046878996+CDS3.285437.55782K562ZNF622
chr194687970646879882+CDS,intron-Proximal3.047978.32002K562PUM1
chr194688671846886847+CDS,intron-Distal,intron-Proximal4.227056.20417HepG2BUD13
chr194688657346886676+CDS,intron-Distal,intron-Proximal3.980333.25678HepG2SF3B4
chr194687886146878910+CDS3.760343.34184HepG2GRWD1
chr194689336546893390+CDS,intron-Proximal3.699265.15749K562YBX3
chr194689327346893341+CDS,intron-Proximal3.945206.42898K562AQR
chr194687982446879904+CDS,intron-Proximal3.784598.67867K562AQR
chr194687980946879881+CDS,intron-Proximal3.138053.69193HepG2PRPF8
chr194689068846890760+CDS,intron-Proximal3.343204.07440K562PRPF8
chr194688668046886867+CDS,intron-Distal,intron-Proximal4.6386315.12562HepG2PRPF8
chr194689042946890491+CDS4.267188.68543HepG2PPIG
chr194689043946890491+CDS3.097813.17744HepG2GRWD1
chr194687981346879864+CDS,intron-Proximal3.335743.99577HepG2BUD13
chr194687975146879837+CDS,intron-Proximal3.315866.21281HepG2GRWD1
chr194689350846893547+CDS,intron-Distal,intron-Proximal3.164683.39477K562BUD13
chr194688810846888169+CDS,intron-Proximal3.048044.28697K562ZNF622
chr194687971646879788+CDS3.072555.76243HepG2BUD13
chr194689353946893594+CDS,intron-Distal,intron-Proximal3.106337.04063K562YBX3
chr194687975946879819+CDS4.0481810.10564K562ZNF800
chr194689067546890710+CDS3.705183.86355HepG2PPIG
chr194689187346891898+CDS3.189968.06227K562YBX3
chr194688702346887128+CDS,intron-Proximal3.398435.87745K562BUD13
chr194688130046881352+intron-Distal4.047503.29248HepG2SUGP2
chr194688100546881057+intron-Distal3.261063.10640HepG2SUGP2
chr194688675046886870+intron-Distal,intron-Proximal3.623777.54465HepG2RBFOX2
chr194688682046886923+intron-Distal,intron-Proximal4.722228.82626HepG2PCBP2
chr194688417846884241+intron-Distal3.896753.33944K562MATR3
chr194689206946892119+intron-Distal,intron-Proximal4.810866.08124K562AGGF1
chr194686528346865397+intron-Distal3.288773.35103HepG2QKI
chr194688012546880248+intron-Distal4.105677.32988HepG2HNRNPM
chr194688396646884026+intron-Distal3.960803.47525K562MATR3
chr194689308146893217+intron-Distal,intron-Proximal5.422477.89532HepG2PCBP2
chr194688433346884388+intron-Distal3.146473.35050HepG2SUGP2
chr194688129546881345+intron-Distal3.894123.53160K562RBFOX2
chr194688376546883836+intron-Distal3.519573.62418K562PTBP1
chr194688378146883846+intron-Distal3.265553.84025HepG2SUGP2
chr194688409946884186+intron-Distal3.995653.27946HepG2HNRNPM
chr194688655546886644+intron-Distal,intron-Proximal3.213426.79180HepG2U2AF2
chr194689270646892787+intron-Distal4.022184.46313K562HNRNPL
chr194689271846892802+intron-Distal4.029483.97888HepG2HNRNPL
chr194688674646886826+intron-Distal,intron-Proximal3.356954.57350K562RBFOX2
chr194688689946886980+intron-Distal,intron-Proximal3.347434.98422K562PRPF8
chr194688399446884035+intron-Distal3.905603.29248HepG2SUGP2
chr194689271146892805+intron-Distal5.2846316.39973K562AGGF1
chr194687984846879898+intron-Proximal3.513064.06757K562UCHL5
chr194689071046890777+intron-Proximal6.0948913.72936K562AQR
chr194689198846892034+intron-Proximal4.804369.04436K562AQR
chr194688695146887021+intron-Proximal4.1472914.08879HepG2PCBP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPP5C is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPP5C is not available on ENCORE database.

  • 76 RBPs can affect the levels of PPP5C.  








The Knockdown/knockout RNA-Seq assay for PPP5C is not available on ENCORE database.





76 RBPs can affect the gene expression of PPP5C :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPP5CENSG00000011485.101031.791801187.93820-0.203301.820601.30860HepG2ACO1
PPP5CENSG00000011485.101000.65690775.653500.367402.534101.57900HepG2ADAR
PPP5CENSG00000011485.101787.556001136.691900.653005.980905.23360HepG2AKAP1
PPP5CENSG00000011485.101871.418801600.436800.225602.341801.70100HepG2AUH
PPP5CENSG00000011485.10623.53130811.85560-0.380802.521701.66290HepG2BCLAF1
PPP5CENSG00000011485.10740.83900965.70300-0.382403.155202.33600HepG2CALR
PPP5CENSG00000011485.10564.20700893.52570-0.663306.133205.01130HepG2CIRBP
PPP5CENSG00000011485.10904.614001187.51490-0.392605.730704.83620HepG2CKAP4
PPP5CENSG00000011485.10614.02830983.25040-0.679307.008205.95300HepG2CPSF6
PPP5CENSG00000011485.101606.038001234.429900.379604.940604.12660HepG2CELF1
PPP5CENSG00000011485.10706.43140893.75450-0.339302.267901.64550HepG2DDX21
PPP5CENSG00000011485.10564.96600875.22830-0.631506.923605.48890HepG2DDX24
PPP5CENSG00000011485.10708.55180935.51260-0.400902.316401.74690HepG2DDX6
PPP5CENSG00000011485.10552.52060823.54080-0.575803.811002.50050HepG2AGO1
PPP5CENSG00000011485.10717.47710899.08850-0.325501.823401.32930HepG2EIF2S1
PPP5CENSG00000011485.10666.36810844.42090-0.341602.479601.45600HepG2EIF3G
PPP5CENSG00000011485.101052.896201309.48440-0.314603.441202.52400HepG2EIF4G1
PPP5CENSG00000011485.10892.391501254.41020-0.491304.565203.53620HepG2EIF4G2
PPP5CENSG00000011485.101576.909101837.57030-0.220702.437901.86710HepG2ETF1
PPP5CENSG00000011485.10835.727401160.68130-0.473904.873803.77100HepG2EWSR1
PPP5CENSG00000011485.10613.70630852.04220-0.473404.050102.70420HepG2FASTKD2
PPP5CENSG00000011485.10558.36890943.47600-0.756804.271202.89810HepG2FUS
PPP5CENSG00000011485.10814.459601114.54940-0.452503.150402.47240HepG2GPKOW
PPP5CENSG00000011485.101182.63670942.143000.327902.187301.56080HepG2HNRNPK
PPP5CENSG00000011485.10800.686501063.63880-0.409702.965602.31720HepG2HNRNPLL
PPP5CENSG00000011485.101291.18200871.290500.5674010.215209.11230HepG2HNRNPU
PPP5CENSG00000011485.10881.950701153.51530-0.387303.465002.55980HepG2MSI2
PPP5CENSG00000011485.10762.891001084.86420-0.508002.731301.76980HepG2MTPAP
PPP5CENSG00000011485.10580.03420943.14940-0.701307.234506.06130HepG2NSUN2
PPP5CENSG00000011485.10639.17380919.16480-0.524104.017203.15770HepG2PABPC4
PPP5CENSG00000011485.101850.401301333.733400.4723010.608909.60770HepG2PUM1
PPP5CENSG00000011485.10941.118601209.96800-0.362502.869002.24490HepG2PUS1
PPP5CENSG00000011485.10880.778201091.39510-0.309302.488401.89050HepG2QKI
PPP5CENSG00000011485.10489.70360861.47810-0.814904.816603.90130HepG2RAVER1
PPP5CENSG00000011485.101164.808901396.92610-0.262202.284401.49680HepG2RBM15
PPP5CENSG00000011485.101191.227901535.85730-0.366604.610903.98680HepG2RBM22
PPP5CENSG00000011485.10683.09640990.55190-0.536105.425104.50940HepG2RBM25
PPP5CENSG00000011485.101116.576301441.31490-0.368302.978502.27260HepG2RPLP0
PPP5CENSG00000011485.101208.69790904.848800.417606.305605.39770HepG2SMN1
PPP5CENSG00000011485.10582.863001171.39790-1.007008.111606.77480HepG2SNRNP70
PPP5CENSG00000011485.101357.667101095.162800.309903.666103.14100HepG2SRSF1
PPP5CENSG00000011485.10578.75660891.00510-0.622509.470408.55600HepG2SRSF9
PPP5CENSG00000011485.10772.85920962.40320-0.316402.266301.41080HepG2SUPT6H
PPP5CENSG00000011485.10722.61560914.58170-0.339902.214901.60050HepG2SUPV3L1
PPP5CENSG00000011485.10816.78050984.47760-0.269401.967001.48040HepG2TAF15
PPP5CENSG00000011485.10731.474501036.82870-0.503304.396103.51040HepG2TARDBP
PPP5CENSG00000011485.10715.44380904.49190-0.338302.630401.81420HepG2TIA1
PPP5CENSG00000011485.10992.428401224.72770-0.303403.435702.67130HepG2UPF1
PPP5CENSG00000011485.101003.039401346.97110-0.425307.451306.66620HepG2ZNF622
PPP5CENSG00000011485.103959.898202518.018500.6531021.6383020.15880K562AGGF1
PPP5CENSG00000011485.103587.572102620.129600.453304.465403.62850K562AKAP8L
PPP5CENSG00000011485.101931.805803196.70450-0.7266011.3614010.29140K562AQR
PPP5CENSG00000011485.10990.727501515.58030-0.613306.673505.30090K562BOP1
PPP5CENSG00000011485.101158.565501611.40900-0.476005.793204.66590K562CPSF6
PPP5CENSG00000011485.102614.267102958.98510-0.178701.900801.34190K562DDX47
PPP5CENSG00000011485.103622.831402819.339100.361706.159104.77060K562DKC1
PPP5CENSG00000011485.102060.791302640.86630-0.357805.500304.53750K562EIF2S2
PPP5CENSG00000011485.101900.092901370.061500.471706.720504.50940K562EWSR1
PPP5CENSG00000011485.101098.181001639.74010-0.578406.551105.21410K562FMR1
PPP5CENSG00000011485.101000.694001389.90130-0.474003.921802.81760K562FTO
PPP5CENSG00000011485.101905.300401480.735400.363604.320402.05050K562FUBP3
PPP5CENSG00000011485.10588.94290903.38020-0.617207.442305.11340K562FUS
PPP5CENSG00000011485.102018.245101632.288000.306103.717303.03130K562FXR1
PPP5CENSG00000011485.101687.056401341.554800.330502.945501.46270K562G3BP1
PPP5CENSG00000011485.10610.07840984.14680-0.689904.097303.19620K562G3BP2
PPP5CENSG00000011485.101043.366801538.42900-0.560205.734204.59550K562GPKOW
PPP5CENSG00000011485.101401.774002101.33960-0.584108.478507.48450K562HNRNPC
PPP5CENSG00000011485.10615.272501313.81020-1.0945012.6046010.49050K562KRR1
PPP5CENSG00000011485.101803.219101474.683600.290102.353601.57520K562MAGOH
PPP5CENSG00000011485.104109.612003114.929000.399705.483804.11340K562MBNL1
PPP5CENSG00000011485.101222.473701501.70790-0.296802.363801.55750K562METAP2
PPP5CENSG00000011485.103454.957404458.04960-0.367703.911602.57210K562MSI2
PPP5CENSG00000011485.102231.541002581.40890-0.210102.676201.88010K562MTPAP
PPP5CENSG00000011485.102996.802602183.344900.456803.336302.34960K562NAA15
PPP5CENSG00000011485.102359.823402868.29540-0.281506.159905.10640K562NSUN2
PPP5CENSG00000011485.101663.005302867.21040-0.7859010.686009.05440K562PCBP3
PPP5CENSG00000011485.101473.624802199.23860-0.577609.446508.00320K562POLR2G
PPP5CENSG00000011485.102653.485702157.779300.298202.435401.66900K562PPIG
PPP5CENSG00000011485.101804.637301432.804500.332803.264602.54900K562PTBP1
PPP5CENSG00000011485.103799.002104563.36040-0.264502.555401.77190K562PUF60
PPP5CENSG00000011485.104172.189904755.79180-0.188902.265701.39530K562PUM2
PPP5CENSG00000011485.103983.390502598.326600.616308.269107.37910K562PUS1
PPP5CENSG00000011485.103316.602902531.779800.389506.200005.33790K562RBM15
PPP5CENSG00000011485.101375.359301022.673400.427404.763103.62940K562SF3B4
PPP5CENSG00000011485.102118.993301404.711800.593008.263107.05070K562SRSF1
PPP5CENSG00000011485.101741.258901371.222000.344603.356202.44280K562TIA1
PPP5CENSG00000011485.102238.649503041.30510-0.4421010.037308.77940K562UPF1
PPP5CENSG00000011485.102728.817903601.21690-0.400204.513303.36850K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPP5C is not available on ENCORE database.





22 RBPs can affect the splicing of PPP5C :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.107000.001790.04916excludedK562AKAP8L
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.146000.000320.07646excludedK562PCBP1
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.214000.000000.00000excludedHepG2U2AF2
SEPPP5CENSG00000011485.10chr19+468866674688673346879623468798314688703646887135-0.099000.001820.02028excludedK562AQR
SEPPP5CENSG00000011485.10chr19+4688666746886733468797094687983146887036468871350.161000.000000.00011includedK562FXR1
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.110000.000440.06406excludedK562DROSHA
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.220000.000000.00000excludedK562PUS1
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.148000.000000.00163excludedK562NSUN2
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.122000.000070.02142excludedK562LARP4
SEPPP5CENSG00000011485.10chr19+4688666746886733468797094687983146887036468871350.093000.000010.00560includedK562APOBEC3C
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.160000.000000.00007excludedK562HNRNPUL1
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.077000.001540.06684excludedHepG2PCBP1
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.145000.000080.01722excludedK562SRSF7
SEPPP5CENSG00000011485.10chr19+4688666746886733468797094687983146887036468871350.136000.000090.02094includedK562RBM22
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.218000.000010.00064excludedK562UTP18
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.316000.000000.00000excludedK562U2AF2
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.236000.000000.00000excludedK562RBM15
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.119000.000360.01242excludedK562AGGF1
SEPPP5CENSG00000011485.10chr19+4688666746886733468797094687983146887036468871350.130000.000010.02277includedK562AARS
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.097000.000570.07753excludedK562ZC3H8
SEPPP5CENSG00000011485.10chr19+4688666746886733468797094687983146887036468871350.103000.001680.05963includedK562PTBP1
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.130000.000020.00739excludedK562NPM1
SEPPP5CENSG00000011485.10chr19+468935404689359946893307468933894689440746894515-0.175000.000170.00429excludedK562HNRNPC
SEPPP5CENSG00000011485.10chr19+468866674688673346879709468798314688703646887135-0.156000.000190.00471excludedK562HNRNPC
RIPPP5CENSG00000011485.10chr19+4689062246891705468906224689071046891664468917050.053000.003040.04273includedK562SF3B4
RIPPP5CENSG00000011485.10chr19+4689062246891705468906224689071046891664468917050.114000.000000.00000includedK562PUS1
RIPPP5CENSG00000011485.10chr19+4689062246891705468906224689071046891664468917050.081000.000000.00000includedK562AGGF1
RIPPP5CENSG00000011485.10chr19+4689062246891705468906224689071046891664468917050.052000.000010.00066includedK562RBM22
RIPPP5CENSG00000011485.10chr19+4689062246891705468906224689071046891664468917050.064000.000000.00001includedK562AKAP8L
RIPPP5CENSG00000011485.10chr19+4689062246891705468906224689071046891664468917050.074000.000000.00001includedK562UTP18

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPP5C is not avaliable on ENCORE database.