PCCB

General Information

Gene Name       : PCCB
Gene ID             : ENSG00000114054.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PCCB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PCCBENSG00000114054.1364.0062.4263.21ENCSR000AEF
HepG2PCCBENSG00000114054.1369.3970.2669.83ENCSR985KAT
K562PCCBENSG00000114054.1381.7578.5680.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PCCB is not avaliable on ENCORE database.



Proteins bound to RNA
  • PCCB RNA is bound by 15 proteins.  







eCLIP assay for PCCB is not avaliable on ENCORE database.





15 proteins are bound to PCCB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3136047599136047698+3'-UTR,CDS,intron-Distal,intron-Proximal4.384185.12780HepG2G3BP1
chr3136048762136048846+3'-UTR,CDS,intron-Distal,intron-Proximal4.648278.83026K562RPS3
chr3136048894136048982+3'-UTR,intron-Distal,intron-Proximal3.718725.00403K562IGF2BP1
chr3136048746136048812+3'-UTR,CDS,intron-Distal,intron-Proximal3.853713.15159HepG2LARP4
chr3135975395135975465+CDS,intron-Distal,intron-Proximal3.781185.40651HepG2PPIG
chr3136002707136002789+CDS4.7149710.25987K562RPS3
chr3135979314135979408+CDS,intron-Distal,intron-Proximal3.355645.82046K562SF3B4
chr3136002673136002730+CDS,intron-Proximal4.220984.12139K562DDX24
chr3136002672136002784+CDS,intron-Proximal3.355996.12893K562BUD13
chr3136045719136045790+CDS,intron-Distal,intron-Proximal3.543903.99908K562BUD13
chr3136016827136016915+CDS,intron-Proximal3.897005.20093K562DDX24
chr3135980745135980859+CDS,intron-Distal,intron-Proximal5.472878.26501K562SF3B4
chr3136035801136035853+CDS,intron-Distal5.268508.98683K562LIN28B
chr3136012594136012708+CDS,intron-Proximal3.085703.80468K562BUD13
chr3136012597136012698+CDS,intron-Proximal3.232354.96885HepG2G3BP1
chr3135969222135969326+CDS,intron-Proximal4.498497.45603K562RPS3
chr3135975395135975450+CDS,intron-Distal,intron-Proximal3.919383.39686HepG2G3BP1
chr3135975382135975442+CDS,intron-Distal,intron-Proximal4.194136.08151K562BUD13
chr3135975430135975585+CDS,intron-Distal,intron-Proximal6.4798015.92026K562EFTUD2
chr3136002704136002789+CDS3.652215.41973HepG2G3BP1
chr3136019862136019911+CDS,intron-Distal,intron-Proximal3.238873.65452K562BUD13
chr3136046000136046060+CDS,intron-Distal5.318209.53277K562RPS3
chr3136012646136012703+CDS3.849946.06308HepG2PPIG
chr3136002730136002784+CDS3.870763.87632K562DDX24
chr3135989837135989877+intron-Distal3.860935.20960K562EXOSC5
chr3135991330135991363+intron-Distal4.249733.59909K562EXOSC5
chr3136038824136038864+intron-Distal5.233818.69493K562EXOSC5
chr3136038584136038614+intron-Distal3.735284.61282K562EXOSC5
chr3136039332136039352+intron-Distal4.618215.76606K562EXOSC5
chr3136040834136040866+intron-Distal4.618215.76606K562EXOSC5
chr3136004142136004284+intron-Distal4.322323.74583HepG2PTBP1
chr3136039457136039506+intron-Distal4.8212111.90352K562EXOSC5
chr3135974835135974884+intron-Distal,intron-Proximal3.127683.26275K562BUD13
chr3135993048135993182+intron-Distal3.012015.13755K562EXOSC5
chr3136041994136042068+intron-Distal4.061823.90241K562MATR3
chr3135991628135991739+intron-Distal5.5619811.33292K562EXOSC5
chr3136040696136040769+intron-Distal5.260399.35305K562EXOSC5
chr3135990074135990111+intron-Distal4.465794.80466K562EXOSC5
chr3136038720136038751+intron-Distal3.249734.46778K562EXOSC5
chr3136039211136039252+intron-Distal3.698337.86844K562EXOSC5
chr3135990007135990074+intron-Distal3.500987.70039K562EXOSC5
chr3136041170136041205+intron-Distal4.686976.08953K562EXOSC5
chr3136039001136039048+intron-Distal5.5955311.33292K562EXOSC5
chr3135989353135989401+intron-Distal4.3153512.15449K562EXOSC5
chr3136039657136039718+intron-Distal5.5277611.66247K562EXOSC5
chr3136051307136051423+intron-Distal4.032213.74511K562IGF2BP1
chr3136039718136039762+intron-Distal4.015987.01277K562EXOSC5
chr3135991471135991526+intron-Distal4.542213.59909K562EXOSC5
chr3135991974135992015+intron-Distal4.249733.59917K562EXOSC5
chr3136041592136041659+intron-Distal3.981648.47592K562EXOSC5
chr3135990598135990632+intron-Distal3.249733.15041K562EXOSC5
chr3135974817135974882+intron-Distal,intron-Proximal4.469216.48405K562AQR
chr3136039917136039963+intron-Distal3.530676.13002K562EXOSC5
chr3136051044136051152+intron-Distal3.217707.37538K562UPF1
chr3135990482135990513+intron-Distal4.431025.12361K562EXOSC5
chr3135979442135979528+intron-Distal,intron-Proximal3.584374.75435K562EFTUD2
chr3136041238136041259+intron-Distal4.118213.59909K562EXOSC5
chr3136041074136041148+intron-Distal3.470028.27886K562EXOSC5
chr3136050104136050164+intron-Distal3.463623.66308K562UPF1
chr3136041767136041795+intron-Distal3.304823.72904K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PCCB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PCCB is not available on ENCORE database.

  • 101 RBPs can affect the levels of PCCB.  








The Knockdown/knockout RNA-Seq assay for PCCB is not available on ENCORE database.





101 RBPs can affect the gene expression of PCCB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PCCBENSG00000114054.9978.706001218.96290-0.316703.814203.12140HepG2ACO1
PCCBENSG00000114054.9723.75680939.09680-0.375802.552001.59400HepG2ADAR
PCCBENSG00000114054.91751.884502089.89440-0.254502.897402.19700HepG2AUH
PCCBENSG00000114054.9688.74890938.31240-0.446104.033202.55530HepG2BUD13
PCCBENSG00000114054.91023.927501218.53710-0.251002.746602.08210HepG2CKAP4
PCCBENSG00000114054.91269.114501598.23640-0.332703.600402.88620HepG2CELF1
PCCBENSG00000114054.91397.534001718.19200-0.298003.502302.68540HepG2DAZAP1
PCCBENSG00000114054.91273.855701042.741800.288702.255601.44130HepG2DDX24
PCCBENSG00000114054.91088.374301537.89340-0.498803.683502.97900HepG2DDX6
PCCBENSG00000114054.91228.78610960.858500.354702.317401.47220HepG2EEF2
PCCBENSG00000114054.91064.841001478.55440-0.473503.880903.18560HepG2EIF2S1
PCCBENSG00000114054.9771.22770950.04830-0.300802.389201.30440HepG2EIF2S2
PCCBENSG00000114054.91294.313001634.04430-0.336302.003901.45700HepG2EIF4A3
PCCBENSG00000114054.91245.419801624.00330-0.382902.950002.10990HepG2EIF4G2
PCCBENSG00000114054.91787.234102399.63830-0.425107.128406.23800HepG2ETF1
PCCBENSG00000114054.91150.375501529.31210-0.410802.909002.22730HepG2G3BP1
PCCBENSG00000114054.9634.721501110.18070-0.806608.626506.82640HepG2GNB2L1
PCCBENSG00000114054.91270.06400891.574900.510403.957703.20320HepG2GPKOW
PCCBENSG00000114054.9739.80970954.66470-0.367802.542701.92050HepG2HNRNPA1
PCCBENSG00000114054.9663.692101061.90310-0.678107.645806.53950HepG2HNRNPC
PCCBENSG00000114054.9993.923401565.04910-0.6550013.0777011.71390HepG2HNRNPL
PCCBENSG00000114054.91140.780601554.55070-0.446503.542302.78800HepG2IGF2BP2
PCCBENSG00000114054.91219.029401649.05160-0.435903.380502.65460HepG2MAGOH
PCCBENSG00000114054.9871.378401658.31450-0.9283011.5169010.29370HepG2MATR3
PCCBENSG00000114054.9799.764101023.44630-0.355802.870502.04710HepG2MSI2
PCCBENSG00000114054.91249.296601697.40420-0.442203.372702.67610HepG2NCBP2
PCCBENSG00000114054.91121.441801703.77200-0.603409.541408.15080HepG2NOL12
PCCBENSG00000114054.9408.98410899.63640-1.137309.033607.38960HepG2PABPC1
PCCBENSG00000114054.91163.582601511.77380-0.377702.618301.91390HepG2PABPC4
PCCBENSG00000114054.9786.041101044.13290-0.409604.871803.78620HepG2PARN
PCCBENSG00000114054.91264.105501544.51710-0.289003.493802.82950HepG2PCBP1
PCCBENSG00000114054.9808.175501104.72270-0.450902.381001.41430HepG2PCBP2
PCCBENSG00000114054.91344.479501571.57360-0.225202.348401.83730HepG2PTBP1
PCCBENSG00000114054.91288.558601626.48390-0.336002.680302.09180HepG2PUF60
PCCBENSG00000114054.91440.745101726.68320-0.261202.502301.93240HepG2PUM1
PCCBENSG00000114054.91345.387501725.36060-0.358903.503302.75250HepG2PUM2
PCCBENSG00000114054.91423.603701241.569200.197301.902401.37200HepG2PUS1
PCCBENSG00000114054.9631.932501066.14880-0.754604.440403.55860HepG2RAVER1
PCCBENSG00000114054.91018.096601330.00080-0.385603.790702.80500HepG2RBM15
PCCBENSG00000114054.9939.515501544.75670-0.7174011.278209.97650HepG2RBM25
PCCBENSG00000114054.91244.162801749.03570-0.491408.574507.71890HepG2NELFE
PCCBENSG00000114054.91386.895301628.94340-0.232102.438201.85490HepG2RECQL
PCCBENSG00000114054.9532.47580895.20330-0.749506.792905.62180HepG2RRP9
PCCBENSG00000114054.91278.395601636.26530-0.356104.929804.17620HepG2SF3B4
PCCBENSG00000114054.9418.35390937.04480-1.1634010.548509.03320HepG2SNRNP70
PCCBENSG00000114054.91284.872902265.21530-0.8180021.2514020.20360HepG2SRFBP1
PCCBENSG00000114054.92340.113701707.884500.454309.050108.30480HepG2SRSF1
PCCBENSG00000114054.9591.25620906.23380-0.616104.313103.03510HepG2SRSF3
PCCBENSG00000114054.91107.429101606.03430-0.536307.643506.67140HepG2SRSF5
PCCBENSG00000114054.9917.353901389.43600-0.5989012.2419011.22670HepG2SRSF9
PCCBENSG00000114054.9708.93540996.32360-0.491002.463201.33110HepG2SUB1
PCCBENSG00000114054.9617.467501034.18090-0.7441014.5909013.43900HepG2TRIM56
PCCBENSG00000114054.9598.070601081.82670-0.8551010.667009.41280HepG2U2AF1
PCCBENSG00000114054.9474.955701682.21450-1.8245037.2425034.35530HepG2UBE2L3
PCCBENSG00000114054.91386.496101094.550000.341004.328603.60620HepG2UTP3
PCCBENSG00000114054.9876.428901246.86230-0.508608.543207.71830HepG2ZNF622
PCCBENSG00000114054.94521.449103322.237200.4445011.4009010.34370K562AGGF1
PCCBENSG00000114054.94452.629303650.747500.286402.748201.77040K562AKAP8
PCCBENSG00000114054.94831.236503456.965700.482806.685105.63730K562AKAP8L
PCCBENSG00000114054.91862.019903764.03430-1.0154021.6220020.15910K562AQR
PCCBENSG00000114054.94414.205303627.240800.283203.345702.33280K562ATP5C1
PCCBENSG00000114054.9776.756501123.47210-0.532404.085003.02310K562BOP1
PCCBENSG00000114054.91239.241101648.34050-0.411603.042801.54110K562BUD13
PCCBENSG00000114054.9943.936601200.70470-0.347102.526201.52840K562CCAR1
PCCBENSG00000114054.91659.967802740.92810-0.723504.983103.50540K562CNOT7
PCCBENSG00000114054.92130.477902709.74970-0.347005.033604.19050K562DDX47
PCCBENSG00000114054.94500.293503719.771400.274704.060802.97170K562DKC1
PCCBENSG00000114054.9892.014501291.18430-0.533605.434803.54620K562DNAJC21
PCCBENSG00000114054.92753.806801973.347000.480703.429401.99740K562EEF2
PCCBENSG00000114054.91198.866501906.46410-0.669208.692306.99060K562EFTUD2
PCCBENSG00000114054.91743.077202402.35580-0.462808.203907.06540K562EIF2S2
PCCBENSG00000114054.9828.075901221.34480-0.560602.971901.92560K562EIF3A
PCCBENSG00000114054.91585.183702040.94760-0.364602.450801.48350K562EIF3D
PCCBENSG00000114054.91660.568102334.39210-0.491405.846004.65970K562EIF4A3
PCCBENSG00000114054.93607.412104134.51250-0.196802.522001.62120K562EIF4G2
PCCBENSG00000114054.91528.846701873.83260-0.293502.548601.33890K562EXOSC5
PCCBENSG00000114054.92089.048401701.145800.296202.410001.61830K562FIP1L1
PCCBENSG00000114054.91246.624101664.13080-0.416703.308302.05530K562FKBP4
PCCBENSG00000114054.9723.039401215.43020-0.749309.251807.63850K562FMR1
PCCBENSG00000114054.9674.281201030.16870-0.611505.473204.13590K562FTO
PCCBENSG00000114054.91701.746402427.66590-0.512609.901308.83960K562FXR1
PCCBENSG00000114054.91634.733002108.69120-0.367302.151201.53920K562G3BP2
PCCBENSG00000114054.9809.822301140.56090-0.494104.768203.73010K562GPKOW
PCCBENSG00000114054.92550.771003201.34230-0.327702.719301.96850K562GRSF1
PCCBENSG00000114054.91800.942802564.85830-0.510103.038901.39170K562HNRNPAB
PCCBENSG00000114054.9566.966501915.60520-1.7565057.3974054.84980K562HNRNPC
PCCBENSG00000114054.92019.563602449.00970-0.278202.455601.46730K562HNRNPL
PCCBENSG00000114054.94647.881503668.608900.341203.830302.83670K562KIF1C
PCCBENSG00000114054.9633.32720973.85190-0.620804.305403.11240K562KRR1
PCCBENSG00000114054.9874.363101113.30750-0.348502.732301.86160K562METAP2
PCCBENSG00000114054.93532.531904406.85710-0.319003.092901.89370K562MSI2
PCCBENSG00000114054.91849.065302243.29640-0.278803.994103.03730K562MTPAP
PCCBENSG00000114054.92169.380602492.47560-0.200303.070002.28730K562NSUN2
PCCBENSG00000114054.91508.340502633.22490-0.803906.679504.77960K562PABPC1
PCCBENSG00000114054.91661.839802324.37200-0.484105.845204.40780K562PCBP2
PCCBENSG00000114054.91550.916502383.51070-0.620006.865005.55290K562PCBP3
PCCBENSG00000114054.91233.554201828.26550-0.567708.576707.19600K562POLR2G
PCCBENSG00000114054.91204.125201855.21670-0.623607.569206.32640K562PRPF8
PCCBENSG00000114054.91285.704401717.62290-0.417902.946102.00810K562PSIP1
PCCBENSG00000114054.92663.966604510.96680-0.7599015.1015013.17210K562PUF60
PCCBENSG00000114054.93738.283204798.81840-0.360305.521703.97280K562PUM1
PCCBENSG00000114054.93415.212104701.18010-0.4610010.346808.46400K562PUM2
PCCBENSG00000114054.94119.249703428.166300.264802.107601.62120K562PUS1
PCCBENSG00000114054.94118.396203340.393300.302004.257203.53700K562RBM15
PCCBENSG00000114054.91746.567602433.57680-0.478605.455204.22800K562RBM22
PCCBENSG00000114054.91642.535602561.01790-0.640808.195406.24480K562NELFE
PCCBENSG00000114054.92098.849801706.450500.298504.081502.17310K562RPS10
PCCBENSG00000114054.91288.354201889.53080-0.552505.140104.02430K562RPS19
PCCBENSG00000114054.91750.500302459.47920-0.490608.806107.40860K562SF3A3
PCCBENSG00000114054.9714.214501084.65160-0.602804.984603.65430K562SF3B1
PCCBENSG00000114054.91708.491302192.29310-0.359704.236003.17270K562SF3B4
PCCBENSG00000114054.91429.751201795.86420-0.328902.214001.31090K562SUPV3L1
PCCBENSG00000114054.91693.906302518.27240-0.572106.881805.71750K562TARDBP
PCCBENSG00000114054.91644.899902197.65590-0.418004.215802.21330K562TBRG4
PCCBENSG00000114054.91173.627901652.01790-0.493304.416503.21420K562TIAL1
PCCBENSG00000114054.91452.538001755.49750-0.273302.186101.36010K562TRIM56
PCCBENSG00000114054.91793.872202110.71700-0.234702.069101.37550K562U2AF2
PCCBENSG00000114054.93310.975305086.59670-0.6194012.426109.77810K562UBE2L3
PCCBENSG00000114054.91496.479201900.89450-0.345102.745601.73060K562UCHL5
PCCBENSG00000114054.91550.009102642.82700-0.7698025.1802023.28040K562UPF1
PCCBENSG00000114054.92010.106102559.34650-0.348502.473101.34300K562UTP3
PCCBENSG00000114054.93477.913904240.12960-0.285902.567201.74190K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PCCB is not available on ENCORE database.





12 RBPs can affect the splicing of PCCB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPCCBENSG00000114054.9chr3+1359791041359791971359753961359754651359793201359793770.089000.000010.00229includedHepG2PRPF8
SEPCCBENSG00000114054.9chr3+135974697135974817135969147135969400135979320135979377-0.204000.001340.01802excludedHepG2U2AF2
SEPCCBENSG00000114054.9chr3+135974697135974817135969147135969400135979320135979377-0.167000.002130.04153excludedK562U2AF1
RIPCCBENSG00000114054.9chr3+1360456441360460971360456441360457521360459961360460970.120000.000000.00000includedK562PUS1
RIPCCBENSG00000114054.9chr3+1360456441360460971360456441360457521360459961360460970.086000.000000.00000includedK562AGGF1
RIPCCBENSG00000114054.9chr3+1360456441360460971360456441360457521360459961360460970.082000.000000.00000includedK562AKAP8L
RIPCCBENSG00000114054.9chr3+1360456441360460971360456441360457521360459961360460970.070000.000000.00000includedK562RBM15
RIPCCBENSG00000114054.9chr3+1360456441360460971360456441360457521360459961360460970.067000.000000.00000includedK562UTP18
MXEPCCBENSG00000114054.9chr3+136045644136045752136045996136046097136035782136035906136046475136046574-0.110000.000730.014692includedK562DROSHA
MXEPCCBENSG00000114054.9chr3+1360456441360457521360459961360460971360357821360359061360464751360465740.118000.000670.060141includedK562ZNF800
MXEPCCBENSG00000114054.9chr3+135975396135975465135979320135979377135974697135974817135980793135980907-0.220000.000000.000192includedK562HNRNPC
MXEPCCBENSG00000114054.9chr3+1360456441360457521360459961360460971360357821360359061360464751360465740.106000.001360.045781includedK562TAF15

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PCCB is not avaliable on ENCORE database.