TNIK

General Information

Gene Name       : TNIK
Gene ID             : ENSG00000154310.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TNIK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TNIKENSG00000154310.1641.0845.8643.47ENCSR000AEF
HepG2TNIKENSG00000154310.160.300.220.26ENCSR985KAT
K562TNIKENSG00000154310.1629.7626.2528.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TNIK is not avaliable on ENCORE database.



Proteins bound to RNA
  • TNIK RNA is bound by 24 proteins.  







eCLIP assay for TNIK is not avaliable on ENCORE database.





24 proteins are bound to TNIK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3170780500170780548-3'-UTR,intron-Distal5.004145.25389K562UPF1
chr3170779479170779541-3'-UTR,intron-Distal3.139464.44982K562UPF1
chr3171177801171177887-5'-UTR,CDS,intron-Distal,intron-Proximal3.054605.81426K562ZNF622
chr3170879058170879121-CDS,intron-Distal,intron-Proximal3.974444.62864K562ZNF622
chr3170912311170912350-CDS,intron-Distal,intron-Proximal4.505597.60776K562ZNF622
chr3170856104170856169-CDS,intron-Distal,intron-Proximal3.229546.62505K562UCHL5
chr3171087407171087429-CDS,intron-Distal,intron-Proximal3.915594.74268K562UCHL5
chr3170906489170906500-CDS,intron-Distal,intron-Proximal4.851996.63777K562LIN28B
chr3170856045170856086-CDS,intron-Distal4.983407.49801K562ZNF622
chr3170841416170841468-CDS,intron-Distal3.657073.02919K562GRWD1
chr3170908549170908577-CDS,intron-Distal,intron-Proximal5.344337.84234K562ZNF622
chr3170856132170856156-CDS,intron-Distal3.603134.20387K562ZNF622
chr3170846643170846668-CDS,intron-Distal,intron-Proximal3.982366.81811K562UCHL5
chr3170906499170906541-CDS,intron-Distal3.644588.44067K562UCHL5
chr3170906541170906565-CDS,intron-Distal3.738397.45042K562UCHL5
chr3171087429171087477-CDS,intron-Distal,intron-Proximal3.093565.41277K562UCHL5
chr3170841421170841485-CDS,intron-Distal3.738397.45042K562UCHL5
chr3170895115170895170-CDS,intron-Distal,intron-Proximal5.9171317.37647K562LIN28B
chr3170811676170811720-CDS,intron-Distal3.871164.20387K562ZNF622
chr3170846598170846643-CDS,intron-Distal3.400535.17903K562UCHL5
chr3170906558170906622-CDS,intron-Distal,intron-Proximal3.468575.76525K562PUM1
chr3171087405171087474-CDS,intron-Distal,intron-Proximal3.025696.25518K562DDX24
chr3170855979170856027-CDS,intron-Distal,intron-Proximal3.973956.46803K562UCHL5
chr3170843704170843738-CDS,intron-Distal3.603354.74268K562UCHL5
chr3170819240170819335-CDS,intron-Distal4.3598510.73371K562ZNF622
chr3171087407171087447-CDS,intron-Distal,intron-Proximal3.345846.21602K562ZNF622
chr3170819242170819379-CDS,intron-Distal5.3539820.28602K562UCHL5
chr3170800156170800184-CDS,intron-Distal,intron-Proximal3.566134.20387K562ZNF622
chr3170875315170875453-CDS,intron-Distal,intron-Proximal4.5276113.62741K562UCHL5
chr3170858221170858270-CDS,intron-Distal3.436844.17944K562BUD13
chr3170846601170846667-CDS,intron-Distal3.116798.25677K562ZNF622
chr3170908549170908577-CDS,intron-Distal,intron-Proximal3.831785.77244K562UCHL5
chr3170858198170858275-CDS,intron-Distal3.404055.11643K562ZNF622
chr3170906572170906621-CDS,intron-Distal3.813308.63117K562ZNF622
chr3170828523170828612-CDS,intron-Distal4.381557.16955K562UCHL5
chr3170858187170858243-CDS,intron-Distal,intron-Proximal3.581818.77730K562UCHL5
chr3170928916170929014-CDS,intron-Distal3.8518810.17809K562ZNF622
chr3170855979170856009-CDS,intron-Distal,intron-Proximal3.105254.56310K562ZNF622
chr3170828548170828638-CDS,intron-Distal3.904408.63117K562ZNF622
chr3170945958170946008-CDS,intron-Distal3.764098.32162K562ZNF622
chr3170800053170800083-CDS,intron-Distal3.628153.90826K562ZNF622
chr3170841417170841489-CDS,intron-Distal3.366167.01182K562ZNF622
chr3171087309171087434-CDS,intron-Distal,intron-Proximal3.012784.61304K562KHSRP
chr3170906510170906572-CDS,intron-Distal3.1636410.12596K562ZNF622
chr3170856042170856083-CDS,intron-Distal3.956835.08388K562UCHL5
chr3170879057170879105-CDS,intron-Distal,intron-Proximal4.275548.58706K562UCHL5
chr3170819237170819280-CDS,intron-Distal,intron-Proximal3.556703.52794K562ZNF800
chr3171177424171177482-intron-Distal3.409713.07461K562DROSHA
chr3171026146171026198-intron-Distal5.067538.04096K562EXOSC5
chr3171068988171069039-intron-Distal4.505387.46553K562AGGF1
chr3171026131171026190-intron-Distal3.749614.80898K562HNRNPM
chr3171177608171177651-intron-Distal4.789996.48592K562TIA1
chr3171176670171176706-intron-Distal3.789093.14687K562CSTF2T
chr3171125533171125631-intron-Distal3.990433.69425K562TARDBP
chr3171176862171176910-intron-Distal4.223703.82910K562NONO
chr3170926774170926863-intron-Distal4.714927.69118K562HNRNPL
chr3171084888171085072-intron-Distal3.113343.22514K562KHDRBS1
chr3171170473171170542-intron-Distal4.531785.30489K562TARDBP
chr3171177660171177719-intron-Distal4.895779.07352K562EIF4G2
chr3170927920170927997-intron-Distal3.522374.41421K562PTBP1
chr3171177424171177478-intron-Distal3.096783.29543K562NONO
chr3171176954171177040-intron-Distal4.767825.54597K562TARDBP
chr3170926710170926774-intron-Distal4.326754.94713K562HNRNPL
chr3171065134171065206-intron-Distal4.072678.63026K562TARDBP
chr3170784121170784247-intron-Distal,intron-Proximal3.147363.87053K562KHSRP
chr3171175847171175940-intron-Distal4.763574.84986K562GTF2F1
chr3171068957171069038-intron-Distal4.180809.80509K562HNRNPL
chr3171176942171177010-intron-Distal4.9023212.95377K562EIF4G2
chr3171175852171175925-intron-Distal4.950366.13283K562NONO
chr3171177594171177647-intron-Distal4.406334.48935K562CSTF2T
chr3171078934171078994-intron-Distal4.959518.15874K562HNRNPM
chr3171064429171064624-intron-Distal,intron-Proximal3.524604.75362K562PTBP1
chr3171177412171177489-intron-Distal3.602263.07368K562TARDBP
chr3170983834170983935-intron-Distal5.5972117.10652K562PTBP1
chr3171176951171177021-intron-Distal3.993213.97692K562IGF2BP1
chr3170852576170852690-intron-Distal4.554054.40618K562PTBP1
chr3171177412171177508-intron-Distal6.5789653.64854K562EIF4G2
chr3171079149171079236-intron-Distal3.628127.98764K562HNRNPM
chr3171152552171152644-intron-Distal3.963913.37923K562KHDRBS1
chr3170788137170788280-intron-Distal4.796764.67693K562PTBP1
chr3171176924171176996-intron-Distal4.398444.48529K562TIA1
chr3171175865171175937-intron-Distal4.245369.77761K562CSTF2T
chr3171177647171177711-intron-Distal4.165257.66029K562CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TNIK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TNIK is not available on ENCORE database.

  • 65 RBPs can affect the levels of TNIK.  








The Knockdown/knockout RNA-Seq assay for TNIK is not available on ENCORE database.





65 RBPs can affect the gene expression of TNIK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TNIKENSG00000154310.1240.9662015.790901.375202.670702.07220HepG2ACO1
TNIKENSG00000154310.12126.5135022.293102.5045011.1604010.16070HepG2AKAP1
TNIKENSG00000154310.12125.6468015.860902.9857019.3450017.58320HepG2AKAP8L
TNIKENSG00000154310.1282.1491031.129601.399904.301303.46160HepG2CPSF6
TNIKENSG00000154310.1242.2773020.373101.053101.847501.30210HepG2CELF1
TNIKENSG00000154310.1281.6745035.350201.208102.884001.88560HepG2DDX59
TNIKENSG00000154310.1260.2363018.347301.715004.105903.36480HepG2DDX6
TNIKENSG00000154310.1273.0343017.633402.050206.255305.38240HepG2EIF2S1
TNIKENSG00000154310.1285.7194018.975202.175405.420604.48090HepG2EIF4B
TNIKENSG00000154310.1240.9458013.445901.606503.107401.85750HepG2FAM120A
TNIKENSG00000154310.1282.6956031.184701.406902.854301.82310HepG2FTO
TNIKENSG00000154310.1212.3492035.28550-1.514702.166601.59630HepG2GPKOW
TNIKENSG00000154310.126.4437033.67390-2.385703.665302.95090HepG2HNRNPLL
TNIKENSG00000154310.1237.8495010.977901.785602.840801.87760HepG2HNRNPM
TNIKENSG00000154310.1259.3405018.970601.645202.946001.81490HepG2NONO
TNIKENSG00000154310.1278.2476013.860302.4970010.113009.19530HepG2PTBP1
TNIKENSG00000154310.1252.0257021.996801.241802.556401.91130HepG2PUM2
TNIKENSG00000154310.1238.0717016.083301.243102.172201.61060HepG2PUS1
TNIKENSG00000154310.1245.2729015.002701.593303.187002.52400HepG2QKI
TNIKENSG00000154310.1246.6275019.300701.272401.989301.38180HepG2RAVER1
TNIKENSG00000154310.1249.9386013.619101.874404.486803.64460HepG2RBM25
TNIKENSG00000154310.1240.0557014.635801.452402.476601.89160HepG2RPS19
TNIKENSG00000154310.1261.8459015.723301.975704.192203.24770HepG2RRP9
TNIKENSG00000154310.1254.3264028.746100.918201.943401.38900HepG2SMN1
TNIKENSG00000154310.1243.4766015.739601.465702.975501.64600HepG2SSRP1
TNIKENSG00000154310.12202.8693027.136402.9021030.9618029.32410HepG2TRIM56
TNIKENSG00000154310.1256.0665013.490702.055106.091405.12200HepG2UPF1
TNIKENSG00000154310.1256.7320014.837201.934805.679704.96900HepG2ZNF622
TNIKENSG00000154310.122354.132301518.447800.632506.680504.79870K562AARS
TNIKENSG00000154310.121515.316901836.82560-0.277602.942101.38670K562AKAP1
TNIKENSG00000154310.123676.630504514.06160-0.296002.602701.96810K562AKAP8L
TNIKENSG00000154310.121405.385103351.27760-1.2537032.7495030.93100K562AQR
TNIKENSG00000154310.123894.247404736.40320-0.282403.573002.52290K562ATP5C1
TNIKENSG00000154310.123217.425602578.667500.319202.475501.65300K562BOP1
TNIKENSG00000154310.121675.713001325.353000.338304.363402.68600K562DDX27
TNIKENSG00000154310.127039.884204076.044100.7883033.3098031.30850K562DDX47
TNIKENSG00000154310.122643.086902276.555200.215302.227001.57100K562EIF2S2
TNIKENSG00000154310.121999.268101358.003600.557902.306801.39760K562EIF3A
TNIKENSG00000154310.122191.487901550.964100.498603.385102.23290K562EIF3D
TNIKENSG00000154310.121538.582301944.64910-0.337902.262401.51820K562EIF4A3
TNIKENSG00000154310.122353.159801784.422800.399004.113902.14210K562FASTKD2
TNIKENSG00000154310.122200.617601474.519800.577608.486206.02000K562FUS
TNIKENSG00000154310.121480.018002022.36370-0.450406.565605.69040K562FXR1
TNIKENSG00000154310.121965.881402740.82860-0.479408.322006.43180K562GLRX3
TNIKENSG00000154310.121707.784903033.58980-0.8289017.7568015.77870K562GRSF1
TNIKENSG00000154310.121194.236001662.24160-0.477003.054602.43070K562HNRNPC
TNIKENSG00000154310.122565.405103683.68020-0.522007.888706.01600K562HNRNPL
TNIKENSG00000154310.121757.850202229.61540-0.343002.398801.53530K562HNRNPM
TNIKENSG00000154310.122672.202803675.38970-0.459905.389104.29440K562HSPD1
TNIKENSG00000154310.122985.238002235.233900.417302.831201.88470K562KRR1
TNIKENSG00000154310.122368.950401608.676800.558307.509405.08920K562LARP7
TNIKENSG00000154310.122131.732902543.97480-0.255102.093501.35740K562MAGOH
TNIKENSG00000154310.122059.874802538.87150-0.301602.923801.97280K562MATR3
TNIKENSG00000154310.122295.804402881.63900-0.327905.751504.61410K562MTPAP
TNIKENSG00000154310.122451.599701941.765700.336303.927202.44240K562NCBP2
TNIKENSG00000154310.123697.787304610.21590-0.318202.981401.42990K562NOL12
TNIKENSG00000154310.122714.518403201.67430-0.238104.768903.82540K562NSUN2
TNIKENSG00000154310.123449.051404330.68670-0.328403.784102.11330K562PNPT1
TNIKENSG00000154310.122138.959903077.21220-0.524706.298404.97440K562PPIG
TNIKENSG00000154310.123437.247704598.45000-0.419905.207704.09170K562PUF60
TNIKENSG00000154310.122676.442701810.908200.563503.422201.81430K562RAVER1
TNIKENSG00000154310.123182.010204361.84370-0.455007.112706.19090K562RBM15
TNIKENSG00000154310.121834.111402370.17880-0.369903.473502.52590K562RBM22
TNIKENSG00000154310.122140.578101435.864600.576005.456104.30610K562RPS19
TNIKENSG00000154310.121363.270101946.92450-0.514106.448904.80090K562SAFB
TNIKENSG00000154310.123770.601003236.846600.220103.752502.68180K562SRPK2
TNIKENSG00000154310.121829.577402422.95190-0.405304.847803.91620K562SRSF1
TNIKENSG00000154310.121852.295102191.58890-0.242702.110601.39210K562SYNCRIP
TNIKENSG00000154310.121814.385502452.27710-0.434604.215803.33660K562TARDBP
TNIKENSG00000154310.124125.124903020.752200.4494012.6950011.04060K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TNIK is not available on ENCORE database.





15 RBPs can affect the splicing of TNIK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETNIKENSG00000154310.12chr3-170783975170784115170781669170781753170784364170784524-0.162000.003410.05514excludedK562SF3B4
SETNIKENSG00000154310.12chr3-1708465021708466671708437001708439401708559791708561680.217000.000270.03632includedK562FMR1
SETNIKENSG00000154310.12chr3-1708249711708249951708192371708194221708258531708259510.171000.000130.00759includedK562FXR1
SETNIKENSG00000154310.12chr3-1708572581708573451708559791708561681708581871708582980.230000.000200.04667includedK562HNRNPA1
SETNIKENSG00000154310.12chr3-1708249711708249951708192371708194221708258531708259510.183000.000060.02003includedK562HNRNPA1
SETNIKENSG00000154310.12chr3-1708249711708249951708192371708194221708258531708259510.146000.000000.00282includedK562APOBEC3C
SETNIKENSG00000154310.12chr3-1708249711708249951708192371708194221708258531708259510.215000.000110.02209includedK562HNRNPM
SETNIKENSG00000154310.12chr3-170846502170846667170843700170843940170855979170856168-0.200000.000010.00202excludedK562HNRNPL
SETNIKENSG00000154310.12chr3-1708249711708249951708192371708194221708258531708259440.141000.000930.03551includedK562TARDBP
SETNIKENSG00000154310.12chr3-170783975170784115170781669170781753170784364170784524-0.073000.002670.05718excludedK562RBM15
SETNIKENSG00000154310.12chr3-1708465021708466671708437001708439401708559791708561680.205000.000470.05138includedK562CPSF6
SETNIKENSG00000154310.12chr3-1708572581708573451708559791708561681708581871708582980.183000.000450.09064includedK562SERBP1
SETNIKENSG00000154310.12chr3-1708249711708249951708192371708194221708258531708259440.614000.000000.00000includedK562PTBP1
SETNIKENSG00000154310.12chr3-1708572581708573451708559791708561681708581871708582980.653000.000000.00000includedK562PTBP1
A3SSTNIKENSG00000154310.12chr3-1709123131709125271709123131709124241709289041709290300.187000.000000.00000longerK562U2AF2
A3SSTNIKENSG00000154310.12chr3-1707839751707841371707839751707841151707843641707845240.145000.000010.00008longerK562AQR
A3SSTNIKENSG00000154310.12chr3-1709459531709460441709459531709460101710874081710874740.051000.013550.06861longerK562AQR
A5SSTNIKENSG00000154310.12chr3-170786636170786786170786717170786786170784364170784524-0.089000.006610.09051shorterK562AQR
MXETNIKENSG00000154310.12chr3-170945953170946010171087408171087474170928904170929030171177795171178197-0.161000.000240.006692includedK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TNIK is not avaliable on ENCORE database.