CMC1

General Information

Gene Name       : CMC1
Gene ID             : ENSG00000187118.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CMC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CMC1ENSG00000187118.1310.298.869.57ENCSR000AEF
HepG2CMC1ENSG00000187118.1312.4221.5817.00ENCSR985KAT
K562CMC1ENSG00000187118.1332.2913.3422.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CMC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CMC1 RNA is bound by 19 proteins.  







eCLIP assay for CMC1 is not avaliable on ENCORE database.





19 proteins are bound to CMC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr32836094128361006+3'-UTR,CDS,intron-Proximal3.993204.69223K562SF3B4
chr32836099228361149+3'-UTR,CDS,intron-Proximal3.033764.89942HepG2GRWD1
chr32836100328361135+3'-UTR,CDS4.097284.37331K562GRWD1
chr32835781028357884+3'-UTR,CDS,intron-Proximal3.938305.18845HepG2U2AF2
chr32835790628358023+3'-UTR,CDS,intron-Distal,intron-Proximal4.784595.26064K562AQR
chr32828312828283231+5'-UTR5.1024013.89420K562DDX3X
chr32828317928283254+5'-UTR4.143434.10192HepG2HNRNPK
chr32828316928283304+5'-UTR,CDS,intron-Proximal3.033603.48949K562DROSHA
chr32831393428313973+intron-Distal5.5999511.99379K562EXOSC5
chr32831485228314925+intron-Distal4.425694.87593HepG2MATR3
chr32831242928312475+intron-Distal3.7345510.01558K562EXOSC5
chr32833458228334630+intron-Distal4.281004.76003K562KHSRP
chr32830879328308880+intron-Distal3.7399510.51920K562KHSRP
chr32830370828303801+intron-Distal3.792964.94624HepG2MATR3
chr32835126728351362+intron-Distal4.4121819.78676HepG2HNRNPL
chr32831399128314079+intron-Distal3.301284.70712HepG2MATR3
chr32831242828312475+intron-Distal3.329813.59523HepG2SUGP2
chr32830372428303799+intron-Distal3.957216.51675HepG2SUGP2
chr32835338328353456+intron-Distal3.775063.24603K562KHSRP
chr32830464728304705+intron-Distal,intron-Proximal3.436224.30679K562KHSRP
chr32832803628328130+intron-Distal4.8731114.21720K562KHSRP
chr32830887128308963+intron-Distal4.226284.36528HepG2U2AF2
chr32830390628303956+intron-Distal3.316016.31916HepG2SUGP2
chr32831954328319620+intron-Distal4.822147.51195K562TARDBP
chr32833622028336296+intron-Distal3.778043.49011K562KHSRP
chr32831403028314070+intron-Distal4.5085210.29529K562EXOSC5
chr32835146428351517+intron-Distal4.418504.27660K562HNRNPL
chr32831418928314280+intron-Distal3.5300510.25284HepG2SUGP2
chr32833429528334378+intron-Distal3.7267111.99390K562KHSRP
chr32830431328304443+intron-Distal4.800427.29443K562MATR3
chr32831323028313278+intron-Distal5.191649.02435K562EXOSC5
chr32831673028316794+intron-Distal4.351057.61413K562EXOSC5
chr32831418528314260+intron-Distal3.796734.26619K562MATR3
chr32834791628347999+intron-Distal3.957253.01445K562EXOSC5
chr32831488028314910+intron-Distal5.236739.02435K562EXOSC5
chr32834217728342265+intron-Distal6.1248714.07031HepG2PCBP2
chr32835156828351661+intron-Distal3.676976.30077K562HNRNPL
chr32835127128351357+intron-Distal3.5565415.69489K562AGGF1
chr32833291528333032+intron-Distal4.7424914.43897K562KHSRP
chr32833448328334538+intron-Distal,intron-Proximal3.960113.21228K562TIA1
chr32834219828342279+intron-Distal3.349353.59765K562ILF3
chr32831261428312651+intron-Distal4.304824.48560K562EXOSC5
chr32832993228329990+intron-Distal3.401217.08481K562KHSRP
chr32832907128329141+intron-Distal3.803356.59336K562KHSRP
chr32831470228314723+intron-Distal5.3903810.67022K562EXOSC5
chr32831313928313222+intron-Distal4.217853.45817K562MATR3
chr32831795428318096+intron-Distal4.759914.17759HepG2QKI
chr32835151728351563+intron-Distal4.267815.18391K562HNRNPL
chr32831644328316495+intron-Distal4.182983.78432HepG2MATR3
chr32831499428315048+intron-Distal5.0338214.16920K562EXOSC5
chr32832788228327943+intron-Distal3.367785.96041K562KHSRP
chr32832794328328036+intron-Distal4.2164712.49723K562KHSRP
chr32835345628353569+intron-Distal3.663365.78005K562KHSRP
chr32831597828316034+intron-Distal4.168324.18579K562MATR3
chr32829289728293028+intron-Distal3.940143.14791K562HNRNPL
chr32835151828351575+intron-Distal3.7933410.22605K562AGGF1
chr32835125828351361+intron-Distal5.1808019.88753K562HNRNPL
chr32831199428312053+intron-Distal5.4657910.34009K562EXOSC5
chr32832622728326303+intron-Distal5.245629.98081K562TARDBP
chr32831397328314014+intron-Distal4.7515212.22629K562EXOSC5
chr32834946428349614+intron-Distal4.320744.75674K562MATR3
chr32832898028329047+intron-Distal4.219769.41035K562KHSRP
chr32831508528315107+intron-Distal5.182278.03988K562EXOSC5
chr32831642728316485+intron-Distal4.178854.47026K562MATR3
chr32832983928329916+intron-Distal4.906788.94695K562KHSRP
chr32833018528330247+intron-Distal3.724316.62503K562KHSRP
chr32829616428296256+intron-Distal4.6291713.69723K562KHSRP
chr32831317328313222+intron-Distal4.075775.50856K562EXOSC5
chr32835136628351463+intron-Distal5.7404828.81979HepG2HNRNPL
chr32831599628316041+intron-Distal3.391365.02053K562EXOSC5
chr32831419028314242+intron-Distal7.6225052.79514K562EXOSC5
chr32830432228304429+intron-Distal3.781953.68462HepG2MATR3
chr32833437828334462+intron-Distal,intron-Proximal4.7640314.00650K562KHSRP
chr32833581328335899+intron-Distal,intron-Proximal3.077093.07751K562KHSRP
chr32833180628331949+intron-Distal3.7038111.90038K562KHSRP
chr32835186128351938+intron-Distal4.381265.91698K562KHSRP
chr32835138128351464+intron-Distal3.1821611.59924K562HNRNPL
chr32835145828351518+intron-Distal4.6354414.52844K562AGGF1
chr32833160528331661+intron-Distal4.569823.35169HepG2U2AF2
chr32831705428317083+intron-Distal4.288733.59909K562EXOSC5
chr32831402328314089+intron-Distal5.241947.38107K562HNRNPM
chr32831371528313736+intron-Distal4.875507.06230K562EXOSC5
chr32831536428315404+intron-Distal5.208508.36828K562EXOSC5
chr32831642528316476+intron-Distal4.976326.73640K562EXOSC5
chr32835135728351458+intron-Distal4.4324729.65894K562AGGF1
chr32831403828314084+intron-Distal3.820195.63625HepG2HNRNPM
chr32834214728342248+intron-Distal4.486384.83379HepG2HNRNPK
chr32831684328316908+intron-Distal4.4442514.58166K562EXOSC5
chr32831684328316945+intron-Distal3.584907.91745HepG2SUGP2
chr32831795128318064+intron-Distal5.5430112.45808K562QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CMC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CMC1 is not available on ENCORE database.

  • 50 RBPs can affect the levels of CMC1.  








The Knockdown/knockout RNA-Seq assay for CMC1 is not available on ENCORE database.





50 RBPs can affect the gene expression of CMC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CMC1ENSG00000187118.864.27840306.82670-2.2550023.3170021.36540HepG2CIRBP
CMC1ENSG00000187118.890.61100153.65710-0.762002.698102.01800HepG2CPSF6
CMC1ENSG00000187118.8160.76980110.606300.539502.254601.65330HepG2DNAJC2
CMC1ENSG00000187118.8237.79590341.22560-0.521002.455901.85220HepG2EIF4A3
CMC1ENSG00000187118.8321.58110463.31160-0.526804.365103.64010HepG2ETF1
CMC1ENSG00000187118.8129.50840199.58340-0.623902.213501.50360HepG2FUBP3
CMC1ENSG00000187118.8194.67450319.36380-0.714104.000903.20880HepG2G3BP1
CMC1ENSG00000187118.898.83630170.44900-0.786202.374101.36720HepG2NONO
CMC1ENSG00000187118.8212.91840315.69380-0.568202.776402.05380HepG2PABPC4
CMC1ENSG00000187118.8253.85490327.33840-0.366801.865101.39880HepG2PTBP1
CMC1ENSG00000187118.8240.43360329.62870-0.455202.498801.86110HepG2PUM2
CMC1ENSG00000187118.8247.44740364.28580-0.557903.487502.89530HepG2NELFE
CMC1ENSG00000187118.8228.95440339.30170-0.567503.617002.92500HepG2RECQL
CMC1ENSG00000187118.8173.64280110.892500.646902.677902.04120HepG2SAFB2
CMC1ENSG00000187118.8248.05570355.70870-0.520003.269902.76650HepG2SRSF1
CMC1ENSG00000187118.8289.43530379.71560-0.391702.458701.96950HepG2SSB
CMC1ENSG00000187118.8220.67260303.56840-0.460102.289901.50030HepG2TUFM
CMC1ENSG00000187118.8198.02560109.127100.859604.223603.28460HepG2UCHL5
CMC1ENSG00000187118.8121.97570171.95610-0.495401.916201.34290HepG2ZC3H8
CMC1ENSG00000187118.81058.67900473.035201.1621023.7253022.17550K562AGGF1
CMC1ENSG00000187118.8787.84400519.822600.599806.061104.46710K562AKAP8
CMC1ENSG00000187118.8929.50110492.221600.917007.596506.46610K562AKAP8L
CMC1ENSG00000187118.8402.09270860.05640-1.0969013.9145012.74260K562AQR
CMC1ENSG00000187118.8791.30510516.472100.615407.880306.21780K562ATP5C1
CMC1ENSG00000187118.8259.81960181.338800.518702.322101.37290K562CCAR1
CMC1ENSG00000187118.8716.98460565.280300.342902.644901.50300K562CCDC124
CMC1ENSG00000187118.8186.91360447.49230-1.2595014.5083011.95890K562CIRBP
CMC1ENSG00000187118.8738.79440555.000300.412603.054601.50850K562DDX19B
CMC1ENSG00000187118.8285.54770429.23370-0.588004.157403.15220K562EIF4A3
CMC1ENSG00000187118.8414.80450289.661700.518003.214702.29780K562FIP1L1
CMC1ENSG00000187118.8146.11740244.68440-0.743803.749502.75010K562FMR1
CMC1ENSG00000187118.8770.61210588.227800.389502.647201.90700K562GRSF1
CMC1ENSG00000187118.8112.17370232.31970-1.050406.370105.50050K562HNRNPC
CMC1ENSG00000187118.8590.01490416.974600.500703.255601.90430K562HNRNPK
CMC1ENSG00000187118.8551.84370392.691900.490803.255402.39410K562HSPD1
CMC1ENSG00000187118.8747.34620522.345600.516702.143201.42720K562KIF1C
CMC1ENSG00000187118.8117.59100196.05160-0.737502.625001.71860K562KRR1
CMC1ENSG00000187118.8791.96460500.033200.663302.810301.72450K562MAK16
CMC1ENSG00000187118.8319.60250437.89890-0.454302.861801.92260K562MATR3
CMC1ENSG00000187118.8835.76290585.162400.514205.064403.75870K562MBNL1
CMC1ENSG00000187118.8256.08760428.64310-0.743106.423704.57990K562NCBP2
CMC1ENSG00000187118.8406.22700532.72420-0.391103.146102.35480K562NSUN2
CMC1ENSG00000187118.8657.36410328.852100.999204.496903.41570K562PPIG
CMC1ENSG00000187118.8778.09160488.098800.672706.134505.36480K562PUS1
CMC1ENSG00000187118.8789.92030475.620100.731809.951608.85400K562RBM15
CMC1ENSG00000187118.8215.40260312.02570-0.534602.936001.55790K562RBM25
CMC1ENSG00000187118.8350.87060525.71950-0.583405.455904.33810K562SF3A3
CMC1ENSG00000187118.8333.63550210.998500.660903.767702.51020K562SRSF4
CMC1ENSG00000187118.8657.20430524.530300.325202.668501.42370K562TROVE2
CMC1ENSG00000187118.8661.016801004.17240-0.603203.005001.53860K562UBE2L3
CMC1ENSG00000187118.8443.56500564.86180-0.348802.580001.88580K562UPF1
CMC1ENSG00000187118.8367.60750502.64040-0.451403.888802.89640K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CMC1 is not available on ENCORE database.





17 RBPs can affect the splicing of CMC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECMC1ENSG00000187118.8chr3+2830478128304871282830852828330328357823283579140.109000.006530.09365includedK562SRSF1
SECMC1ENSG00000187118.8chr3+2829522128295256282831082828330328304781283048710.218000.000000.00001includedHepG2U2AF1
SECMC1ENSG00000187118.8chr3+283047812830487128283085282833032835782328357914-0.137000.000620.02150excludedK562AKAP8L
SECMC1ENSG00000187118.8chr3+2829522128295256282831082828330328304781283048710.072000.000050.02430includedK562PUM1
SECMC1ENSG00000187118.8chr3+2830478128304871282830852828330328357823283579140.164000.000050.00379includedK562FXR1
SECMC1ENSG00000187118.8chr3+283047812830487128283085282833032835782328357914-0.225000.000000.00001excludedK562PUS1
SECMC1ENSG00000187118.8chr3+283047812830487128283085282833032835782328357914-0.206000.000010.00185excludedHepG2DDX6
SECMC1ENSG00000187118.8chr3+2829522128295256282831082828330328304781283048710.268000.000610.06801includedHepG2PCBP2
SECMC1ENSG00000187118.8chr3+2830478128304871282830852828330328357823283579140.172000.000120.00423includedHepG2SRSF1
SECMC1ENSG00000187118.8chr3+2829522128295256282831082828330328304781283048710.109000.000370.02187includedHepG2PCBP1
SECMC1ENSG00000187118.8chr3+2830478128304871282830852828330328357823283579140.136000.001000.04617includedHepG2SF3B4
SECMC1ENSG00000187118.8chr3+2829320228293360282831082828330328295221282952560.217000.003300.08211includedK562UTP18
SECMC1ENSG00000187118.8chr3+283047812830487128283085282833032835782328357914-0.181000.000030.00200excludedK562UTP18
SECMC1ENSG00000187118.8chr3+2829522128295256282831082828330328304781283048710.130000.000160.02313includedHepG2TAF15
SECMC1ENSG00000187118.8chr3+283047812830487128283085282833032835782328357914-0.181000.000000.00014excludedK562HNRNPU
SECMC1ENSG00000187118.8chr3+283047812830487128283085282833032835782328357914-0.167000.000050.00262excludedK562RBM15
SECMC1ENSG00000187118.8chr3+283047812830487128283085282833032835782328357914-0.194000.000000.00015excludedK562AGGF1
SECMC1ENSG00000187118.8chr3+2835824328358350283578432835791428360999283612670.097000.000000.00113includedK562CPSF6
SECMC1ENSG00000187118.8chr3+282952212829525628283108282833032830478128304871-0.197000.000140.03033excludedK562EIF3G

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CMC1 is not avaliable on ENCORE database.