POT1

General Information

Gene Name       : POT1
Gene ID             : ENSG00000128513.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: POT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POT1ENSG00000128513.1442.2230.7536.48ENCSR000AEF
HepG2POT1ENSG00000128513.1413.3819.4616.42ENCSR985KAT
K562POT1ENSG00000128513.1458.9462.6360.78ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • POT1 RNA is bound by 17 proteins.  







eCLIP assay for POT1 is not avaliable on ENCORE database.





17 proteins are bound to POT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7124486995124487015-3'-UTR,CDS,intron-Distal,intron-Proximal4.165184.07825K562YBX3
chr7124482952124483018-3'-UTR,CDS,intron-Distal,intron-Proximal3.024296.78138K562YBX3
chr7124538273124538321-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.430983.76553K562PRPF8
chr7124537112124537252-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.045398.82110K562PRPF8
chr7124480708124480771-3'-UTR,intron-Distal,intron-Proximal,polyA_site4.823636.94732K562KHSRP
chr7124482922124483016-3'-UTR,CDS,intron-Distal,intron-Proximal4.130724.29472K562IGF2BP1
chr7124464003124464091-3'-UTR,CDS,intron-Distal,intron-Proximal4.386755.03175K562IGF2BP1
chr7124482860124482899-3'-UTR,CDS,intron-Distal,intron-Proximal3.819243.19539K562YBX3
chr7124503495124503656-3'-UTR,CDS,intron-Distal,intron-Proximal4.639045.85983HepG2GRWD1
chr7124491885124491918-3'-UTR,CDS,intron-Distal,intron-Proximal4.308433.02181K562PRPF8
chr7124463765124463812-3'-UTR,intron-Distal,intron-Proximal4.719169.89562K562PUM2
chr7124463817124463824-3'-UTR,intron-Distal,intron-Proximal4.977283.00733K562PUM2
chr7124510963124511002-3'-UTR,CDS,intron-Distal,intron-Proximal4.112413.69113K562LIN28B
chr7124499070124499167-3'-UTR,CDS,intron-Distal,intron-Proximal3.252396.76685K562YBX3
chr7124480771124480855-3'-UTR,intron-Distal3.313803.90146K562KHSRP
chr7124537133124537238-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.142103.52965K562EFTUD2
chr7124532320124532344-5'-UTR,CDS,intron-Distal3.922463.83925K562YBX3
chr7124569016124569056-5'-UTR,intron-Distal,intron-Proximal3.667356.20524K562DDX3X
chr7124511025124511095-CDS,intron-Distal4.286284.72754K562YBX3
chr7124544784124544822-intron-Distal4.1322010.62063K562EXOSC5
chr7124509376124509464-intron-Distal3.926904.02199K562HNRNPL
chr7124544212124544257-intron-Distal4.373093.30687K562EXOSC5
chr7124486278124486424-intron-Distal3.860353.26999K562KHSRP
chr7124498632124498701-intron-Distal4.428625.68841K562KHSRP
chr7124514804124514938-intron-Distal4.612909.03914K562PTBP1
chr7124532464124532558-intron-Distal,intron-Proximal5.283838.49499K562KHSRP
chr7124555428124555587-intron-Distal,intron-Proximal3.868228.25843K562PRPF8
chr7124536484124536502-intron-Distal3.021323.28806K562KHSRP
chr7124478981124479147-intron-Distal4.853697.17304K562KHSRP
chr7124562996124563156-intron-Distal4.258273.89080K562EXOSC5
chr7124498701124498776-intron-Distal,intron-Proximal3.906573.90026K562KHSRP
chr7124486156124486238-intron-Distal4.294274.92524K562TARDBP
chr7124533080124533154-intron-Distal3.893004.33990HepG2QKI
chr7124534818124534875-intron-Distal5.263007.30165K562QKI
chr7124498479124498544-intron-Distal4.042234.10688K562KHSRP
chr7124498677124498815-intron-Distal,intron-Proximal3.827013.22073HepG2KHSRP
chr7124544775124544821-intron-Distal3.915903.28572K562HNRNPM
chr7124491738124491827-intron-Distal,intron-Proximal4.182273.16986HepG2QKI
chr7124506873124506951-intron-Distal3.813053.74251K562SAFB2
chr7124509378124509472-intron-Distal4.110213.71677HepG2HNRNPL
chr7124532558124532690-intron-Distal,intron-Proximal3.126378.00348K562KHSRP
chr7124526894124526997-intron-Distal4.002914.28339K562KHDRBS1
chr7124470954124471061-intron-Distal3.406164.56724K562KHSRP
chr7124519863124519964-intron-Distal4.046344.54401K562KHSRP
chr7124533057124533145-intron-Distal4.296565.51743K562QKI
chr7124534820124534886-intron-Distal4.946085.05488HepG2QKI
chr7124545166124545245-intron-Distal5.127606.73640K562EXOSC5
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POT1 is not available on ENCORE database.

  • 55 RBPs can affect the levels of POT1.  








The Knockdown/knockout RNA-Seq assay for POT1 is not available on ENCORE database.





55 RBPs can affect the gene expression of POT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POT1ENSG00000128513.10282.91300407.70050-0.527204.279803.55530HepG2ACO1
POT1ENSG00000128513.10473.75940763.96070-0.689304.856504.17830HepG2AKAP1
POT1ENSG00000128513.10316.94480409.63880-0.370102.313801.60530HepG2AKAP8L
POT1ENSG00000128513.10431.91670632.14320-0.549503.463002.58430HepG2ASCC1
POT1ENSG00000128513.10202.43210343.12570-0.761304.771803.89020HepG2CPSF6
POT1ENSG00000128513.10443.23270586.17660-0.403303.294902.60600HepG2CELF1
POT1ENSG00000128513.10520.41140731.88060-0.492002.731202.10770HepG2DDX3X
POT1ENSG00000128513.10414.30210628.54960-0.601303.744403.03510HepG2DDX6
POT1ENSG00000128513.10350.42300507.72680-0.535003.168502.18680HepG2EEF2
POT1ENSG00000128513.10350.21110604.38980-0.787305.687604.85490HepG2EIF2S1
POT1ENSG00000128513.10354.09950667.99430-0.915706.746605.74600HepG2EIF4A3
POT1ENSG00000128513.10491.36790673.75890-0.455402.788102.09330HepG2FXR1
POT1ENSG00000128513.10502.19830663.50020-0.401802.307801.49800HepG2G3BP2
POT1ENSG00000128513.10183.47920491.31630-1.4210016.9146015.34320HepG2HNRNPC
POT1ENSG00000128513.10455.65370574.20230-0.333602.807602.12950HepG2HNRNPL
POT1ENSG00000128513.10309.88850488.06730-0.655306.774105.86370HepG2HNRNPU
POT1ENSG00000128513.10393.30440635.46750-0.692204.527003.68180HepG2IGF2BP2
POT1ENSG00000128513.10463.10560639.09500-0.464702.264401.37010HepG2KHSRP
POT1ENSG00000128513.10520.76560738.94940-0.504802.908302.05610HepG2LARP4
POT1ENSG00000128513.10510.97490673.99320-0.399502.021701.45720HepG2MAGOH
POT1ENSG00000128513.10372.77680677.80110-0.862507.003506.03410HepG2MATR3
POT1ENSG00000128513.10450.64550693.79610-0.622503.712002.98260HepG2NCBP2
POT1ENSG00000128513.10429.09980618.00390-0.526302.986602.23860HepG2PABPC4
POT1ENSG00000128513.10456.24820554.43610-0.281201.903101.38350HepG2PCBP1
POT1ENSG00000128513.10367.34490564.13630-0.618906.497605.72800HepG2PTBP1
POT1ENSG00000128513.10434.09290596.63740-0.458903.340802.69470HepG2PUF60
POT1ENSG00000128513.10503.40180633.34030-0.331303.027902.41350HepG2PUM1
POT1ENSG00000128513.10477.20930627.84880-0.395803.198502.62540HepG2NELFE
POT1ENSG00000128513.10299.52180401.05240-0.421102.203201.64800HepG2RPS19
POT1ENSG00000128513.10371.65850512.46180-0.463502.392701.64410HepG2RPS2
POT1ENSG00000128513.10374.12090560.11600-0.582203.266302.39880HepG2RPS3A
POT1ENSG00000128513.10231.39340402.50590-0.798705.696004.36010HepG2SERBP1
POT1ENSG00000128513.10359.46240506.85360-0.495704.667203.86820HepG2SMN1
POT1ENSG00000128513.10781.09430613.080800.349302.815802.33920HepG2SRSF1
POT1ENSG00000128513.10609.58820395.330500.624703.673902.50410HepG2SRSF3
POT1ENSG00000128513.10423.40890589.07260-0.476404.564603.79510HepG2SRSF5
POT1ENSG00000128513.10323.09470420.34190-0.379602.148401.52640HepG2SRSF7
POT1ENSG00000128513.10254.50820378.98350-0.574402.926402.23360HepG2SUPV3L1
POT1ENSG00000128513.10675.96070551.014000.294801.888001.40860HepG2TAF15
POT1ENSG00000128513.10201.57000474.21180-1.2343016.3330015.29990HepG2TIAL1
POT1ENSG00000128513.10330.73520478.49030-0.532804.804104.10200HepG2TRIM56
POT1ENSG00000128513.10433.28930582.86230-0.427802.964702.05640HepG2TUFM
POT1ENSG00000128513.10636.25020421.378700.594403.955303.20990HepG2U2AF1
POT1ENSG00000128513.10321.91670470.15140-0.546405.313404.61750HepG2ZNF622
POT1ENSG00000128513.102575.370703123.88480-0.278602.306601.70890K562AKAP8L
POT1ENSG00000128513.101453.707201910.01810-0.393804.242202.91170K562DDX3X
POT1ENSG00000128513.103896.538703078.899300.339706.202405.28120K562DDX47
POT1ENSG00000128513.101307.982001741.88730-0.413304.979603.15000K562EWSR1
POT1ENSG00000128513.101710.120602075.25060-0.279203.208202.56390K562FXR1
POT1ENSG00000128513.103710.245902496.556500.571504.777103.78900K562G3BP2
POT1ENSG00000128513.10970.767401850.11740-0.9304018.4146016.95420K562HNRNPC
POT1ENSG00000128513.102153.012102782.50350-0.370004.067002.75760K562HNRNPL
POT1ENSG00000128513.101663.436502259.60670-0.441904.323303.19670K562HNRNPU
POT1ENSG00000128513.103521.222302895.583700.282102.249501.52800K562HSPD1
POT1ENSG00000128513.102150.080602674.83740-0.315103.137202.15170K562MATR3
POT1ENSG00000128513.101319.663301876.16340-0.507606.385805.02830K562METAP2
POT1ENSG00000128513.101879.374802384.81710-0.343602.549401.61170K562PCBP2
POT1ENSG00000128513.101244.817501658.77920-0.414203.852702.76050K562PSIP1
POT1ENSG00000128513.101608.201902603.88350-0.6952013.1199011.72840K562PTBP1
POT1ENSG00000128513.101908.593402497.23380-0.387803.801702.80530K562RBM22
POT1ENSG00000128513.102040.742102627.84070-0.364803.128901.95920K562NELFE
POT1ENSG00000128513.102253.953401510.837800.577004.666503.60330K562RPS19
POT1ENSG00000128513.101442.364901965.15760-0.446205.168803.65180K562SRSF4
POT1ENSG00000128513.101616.489302583.57130-0.676507.991206.71150K562TARDBP
POT1ENSG00000128513.102065.867802492.09730-0.270602.501701.72900K562TIA1
POT1ENSG00000128513.101015.953601595.49440-0.651206.911605.37590K562TIAL1
POT1ENSG00000128513.103176.897202420.483200.392203.031801.87500K562U2AF1
POT1ENSG00000128513.102939.788802499.665900.233902.187801.47310K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POT1 is not available on ENCORE database.





17 RBPs can affect the splicing of POT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPOT1ENSG00000128513.10chr7-1245327551245328691245323191245324341245372181245372660.478000.000000.00000includedK562SRSF1
SEPOT1ENSG00000128513.10chr7-124475332124475468124467267124467359124481026124481232-0.067000.007070.09632excludedK562SF3B4
SEPOT1ENSG00000128513.10chr7-1245109641245110951245034031245036941245323191245324340.110000.000020.01065includedK562WDR3
SEPOT1ENSG00000128513.10chr7-124555627124555700124538314124538428124568868124569053-0.307000.006430.09206excludedHepG2U2AF1
SEPOT1ENSG00000128513.10chr7-1245327551245328691245323191245324341245372181245372660.121000.000010.00592includedK562PCBP1
SEPOT1ENSG00000128513.10chr7-1245320421245321421245109641245110951245323191245324340.204000.007030.06938includedHepG2U2AF2
SEPOT1ENSG00000128513.10chr7-124469307124469396124467267124467359124475332124475468-0.056000.002360.02516excludedK562AQR
SEPOT1ENSG00000128513.10chr7-124510964124511095124503403124503694124532319124532434-0.129000.000230.01235excludedK562FXR1
SEPOT1ENSG00000128513.10chr7-124499010124499166124493025124493192124503403124503694-0.077000.000690.05435excludedK562SUPV3L1
SEPOT1ENSG00000128513.10chr7-124555627124555700124538314124538428124568868124569053-0.079000.000000.00025excludedK562U2AF1
SEPOT1ENSG00000128513.10chr7-124510964124511095124503403124503694124532319124532434-0.126000.000090.01010excludedK562HNRNPL
SEPOT1ENSG00000128513.10chr7-1245109641245110951245034031245036941245323191245324340.093000.000400.08450includedK562PPIL4
SEPOT1ENSG00000128513.10chr7-124532755124532869124532319124532434124537218124537266-0.058000.000410.08543excludedK562PPIL4
SEPOT1ENSG00000128513.10chr7-124555627124555700124538314124538428124568868124569053-0.098000.000000.00002excludedK562U2AF2
SEPOT1ENSG00000128513.10chr7-1245327551245328691245323191245324341245372181245372660.096000.000800.03159includedK562TARDBP
SEPOT1ENSG00000128513.10chr7-124532755124532869124532319124532434124537218124537266-0.055000.003350.09346excludedK562HNRNPU
SEPOT1ENSG00000128513.10chr7-1245109641245110951245034031245036941245323191245324340.093000.000560.05854includedK562CPSF6
SEPOT1ENSG00000128513.10chr7-1244885931244887131244869951244870521244919251244920050.529000.002160.07025includedHepG2HNRNPC
SEPOT1ENSG00000128513.10chr7-124510964124511095124503403124503694124532319124532434-0.137000.000560.09666excludedK562SAFB
SEPOT1ENSG00000128513.10chr7-1244885931244887131244869951244870521244919251244920050.276000.000000.00000includedK562HNRNPC
SEPOT1ENSG00000128513.10chr7-124469307124469396124467267124467359124475332124475468-0.119000.001570.02793excludedK562HNRNPC
A3SSPOT1ENSG00000128513.10chr7-1244653051244654571244653051244654111244672671244673930.052000.000010.00006longerK562AQR
MXEPOT1ENSG00000128513.10chr7-124503403124503694124510964124511095124499010124499166124532319124532434-0.174000.000130.008972includedK562LIN28B
MXEPOT1ENSG00000128513.10chr7-1244693071244693961244753321244755601244672671244673591244810261244812320.065000.002780.021991includedK562AQR
MXEPOT1ENSG00000128513.10chr7-1244693071244693961244753321244754901244672671244673591244810261244812320.067000.001980.016491includedK562AQR
MXEPOT1ENSG00000128513.10chr7-124503403124503694124510964124511095124499010124499166124532319124532434-0.141000.003260.051022includedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for POT1 is not avaliable on ENCORE database.