HP

General Information

Gene Name       : HP
Gene ID             : ENSG00000257017.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HP)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HPENSG00000257017.80.000.000.00ENCSR000AEF
HepG2HPENSG00000257017.8463.31477.08470.19ENCSR985KAT
K562HPENSG00000257017.80.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HP is not avaliable on ENCORE database.



Proteins bound to RNA
  • HP RNA is bound by 6 proteins.  







eCLIP assay for HP is not avaliable on ENCORE database.





6 proteins are bound to HP RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr167209469872094732+3'-UTR,CDS,intron-Distal3.5635016.11511HepG2SND1
chr167209462372094691+3'-UTR,CDS,intron-Distal3.179754.63944HepG2LARP4
chr167209454972094615+3'-UTR,CDS,intron-Distal,intron-Proximal3.2976130.27705HepG2SND1
chr167209463672094698+3'-UTR,CDS,intron-Distal3.6976656.10827HepG2SND1
chr167209454172094623+3'-UTR,CDS,intron-Distal,intron-Proximal4.025694.65197HepG2LARP4
chr167209470972094774+3'-UTR,CDS,intron-Distal5.1188130.37647HepG2RPS3
chr167209473272094772+3'-UTR,CDS,intron-Distal4.3530029.68069HepG2SND1
chr167209463972094697+3'-UTR,CDS,intron-Distal4.8490613.92483HepG2RPS3
chr167209450272094599+3'-UTR,CDS,intron-Distal,intron-Proximal4.0003410.84448HepG2RPS3
chr167208854372088556+5'-UTR,CDS4.450857.41870HepG2DDX3X
chr167209440072094447+CDS,intron-Distal4.5228536.22586HepG2SND1
chr167209215272092182+CDS,intron-Distal,intron-Proximal3.039074.76040HepG2SND1
chr167209410372094146+CDS,intron-Distal,intron-Proximal5.335058.26344HepG2RPS3
chr167209411772094148+CDS,intron-Distal,intron-Proximal3.9646916.08849HepG2SND1
chr167209134872091365+CDS,intron-Distal3.069134.76040HepG2SND1
chr167209430472094390+CDS,intron-Distal6.2171425.02446HepG2LIN28B
chr167209438472094400+CDS,intron-Distal3.7446610.18408HepG2SND1
chr167209439672094423+CDS,intron-Distal4.625336.05571HepG2RPS3
chr167209424872094316+CDS,intron-Distal3.9075513.78231HepG2SND1
chr167209436372094372+CDS,intron-Distal3.913606.63492HepG2SND1
chr167209005872090125+CDS,intron-Distal,intron-Proximal4.2905727.57290HepG2DDX3X
chr167209005772090118+CDS,intron-Distal,intron-Proximal5.0824612.82650HepG2RPS3
chr167209424972094318+CDS,intron-Distal3.273553.71296HepG2BCLAF1
chr167209445872094502+CDS,intron-Distal,intron-Proximal4.413876.49041HepG2RPS3
chr167209439072094422+CDS,intron-Distal4.638025.09917HepG2LIN28B
chr167209451472094549+CDS,intron-Distal,intron-Proximal3.2619930.66579HepG2SND1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HP is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HP is not available on ENCORE database.

  • 159 RBPs can affect the levels of HP.  








The Knockdown/knockout RNA-Seq assay for HP is not available on ENCORE database.





159 RBPs can affect the gene expression of HP :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HPENSG00000257017.410549.935008005.268600.398104.992003.59300HepG2AATF
HPENSG00000257017.411000.156104461.597901.3018022.2162020.05650HepG2ABCF1
HPENSG00000257017.46287.517004263.695500.5603014.8116013.64170HepG2ACO1
HPENSG00000257017.48746.259606562.153300.414404.428103.20210HepG2ADAR
HPENSG00000257017.42259.882001435.557200.654505.079201.82730HepG2AGGF1
HPENSG00000257017.43494.682307222.62090-1.0474017.5742016.35360HepG2AKAP1
HPENSG00000257017.48179.174003927.883801.0581019.1897016.76640HepG2AKAP8
HPENSG00000257017.424156.923905975.966602.0151077.2006074.08690HepG2ASCC1
HPENSG00000257017.47325.667804001.544500.8723021.2094019.63500HepG2AUH
HPENSG00000257017.42250.111906310.44860-1.4877033.3848029.85500HepG2BCCIP
HPENSG00000257017.412489.380505483.461901.1874026.6211024.34180HepG2BCLAF1
HPENSG00000257017.411625.021403342.517101.7981064.3746060.01190HepG2BUD13
HPENSG00000257017.42757.752904900.71070-0.8295017.0783015.46110HepG2CALR
HPENSG00000257017.42992.22160754.469801.9876026.3657022.61460HepG2CDC40
HPENSG00000257017.415164.023805677.626801.4172041.9347039.52590HepG2CIRBP
HPENSG00000257017.43058.028704263.07040-0.4793015.8031014.48790HepG2CKAP4
HPENSG00000257017.4908.443604943.49670-2.4441049.1314046.26130HepG2CNOT7
HPENSG00000257017.44580.728601561.545201.5525017.5064015.95430HepG2CPSF6
HPENSG00000257017.47603.725403673.956801.0493031.3933028.32110HepG2CPSF7
HPENSG00000257017.49731.012606729.458800.5320011.772009.75880HepG2YBX3
HPENSG00000257017.42150.293703898.17130-0.8583012.8503010.84870HepG2CSTF2
HPENSG00000257017.45769.082308195.87820-0.506603.989202.24970HepG2CSTF2T
HPENSG00000257017.414496.464509550.185900.602007.408206.45190HepG2CELF1
HPENSG00000257017.46355.8567010267.90600-0.6920039.8464037.69140HepG2DAZAP1
HPENSG00000257017.44588.872303943.446100.218603.666702.72560HepG2DDX19B
HPENSG00000257017.45766.931306738.74390-0.224702.770901.61000HepG2DDX1
HPENSG00000257017.46121.394908643.23110-0.497708.952807.33820HepG2DDX24
HPENSG00000257017.413761.857705805.481901.2451023.5424020.49470HepG2DDX27
HPENSG00000257017.42748.059904700.47920-0.7744011.146908.70470HepG2DDX28
HPENSG00000257017.42827.983106918.41140-1.2907030.2805028.45660HepG2DDX3X
HPENSG00000257017.44185.616905510.28540-0.396705.426203.60350HepG2DDX52
HPENSG00000257017.416721.206206204.390301.4302016.9908015.30830HepG2DDX55
HPENSG00000257017.426656.460305943.795702.1649071.9750069.56700HepG2DDX6
HPENSG00000257017.418028.451504079.279202.14380217.08400214.05540HepG2DKC1
HPENSG00000257017.43395.335806607.67660-0.9606040.0600037.81120HepG2DNAJC21
HPENSG00000257017.44941.708506549.54340-0.4064013.5490012.21640HepG2DNAJC2
HPENSG00000257017.423805.994006573.945901.8564077.5478074.32450HepG2EEF2
HPENSG00000257017.48194.704905479.888300.580407.894106.02540HepG2EFTUD2
HPENSG00000257017.412836.568708133.502500.658206.709905.01000HepG2AGO1
HPENSG00000257017.42899.371805713.18330-0.9786018.0189016.59630HepG2EIF2S1
HPENSG00000257017.47738.814105336.290100.536206.511305.17090HepG2EIF3D
HPENSG00000257017.415828.032008341.161600.9241029.1979026.52690HepG2EIF3G
HPENSG00000257017.421064.825909704.410601.1180013.3297011.63500HepG2EIF4G2
HPENSG00000257017.42525.510803864.70110-0.613809.063507.26290HepG2ESF1
HPENSG00000257017.46142.865904593.905100.419102.137401.59530HepG2ETF1
HPENSG00000257017.43545.042604166.66000-0.233102.057701.33910HepG2EWSR1
HPENSG00000257017.43605.867902092.604700.784904.221301.73210HepG2EXOSC5
HPENSG00000257017.46025.741207902.51180-0.391203.774901.76780HepG2EXOSC9
HPENSG00000257017.43743.015608417.52140-1.1692038.2949035.29410HepG2FASTKD2
HPENSG00000257017.412123.325305164.340501.2310028.1622024.76190HepG2FKBP4
HPENSG00000257017.415683.087809606.919400.707009.740406.80880HepG2FMR1
HPENSG00000257017.43324.246804316.05960-0.376704.525803.53540HepG2FUBP3
HPENSG00000257017.48680.204406371.012200.446104.676103.79270HepG2FXR1
HPENSG00000257017.422111.132507544.511201.5512047.1436043.61340HepG2GNB2L1
HPENSG00000257017.44027.054501769.903601.1860022.5545020.91640HepG2GPKOW
HPENSG00000257017.41797.149104575.86680-1.3483019.5971016.79210HepG2GRSF1
HPENSG00000257017.411384.377007003.026500.700909.149106.20150HepG2GRWD1
HPENSG00000257017.45296.377009351.66710-0.820207.585405.17760HepG2GTF2F1
HPENSG00000257017.42227.279304178.24190-0.907607.262004.96160HepG2HNRNPA0
HPENSG00000257017.43602.998006670.98230-0.8887021.7666020.24910HepG2HNRNPA1
HPENSG00000257017.424180.338609436.928401.35730110.70030106.79660HepG2HNRNPA2B1
HPENSG00000257017.412289.910407420.305800.7278015.4777013.96660HepG2HNRNPC
HPENSG00000257017.49306.176003880.838501.2617037.4580035.34430HepG2HNRNPF
HPENSG00000257017.47122.414105985.204000.250902.018801.41590HepG2HNRNPK
HPENSG00000257017.46951.402209353.00690-0.4281015.8382014.34220HepG2HNRNPL
HPENSG00000257017.41987.336003108.15820-0.6452011.7820010.06170HepG2HNRNPM
HPENSG00000257017.49645.296004277.017601.173102.735301.51620HepG2HSPD1
HPENSG00000257017.410488.466203821.492701.4565068.2715065.60360HepG2IGF2BP1
HPENSG00000257017.49037.012406006.661400.589205.516504.59300HepG2IGF2BP2
HPENSG00000257017.41666.028605637.79980-1.7587013.5822011.59890HepG2IGF2BP3
HPENSG00000257017.44853.182707529.46740-0.6336034.3111032.12000HepG2ILF2
HPENSG00000257017.43411.572904819.00790-0.498303.304501.84330HepG2ILF3
HPENSG00000257017.412278.290306042.049801.0229012.4560010.25160HepG2KHSRP
HPENSG00000257017.44423.852603897.739800.182602.971201.91950HepG2KIF1C
HPENSG00000257017.417896.592308983.278800.9943014.8922013.00140HepG2LARP4
HPENSG00000257017.45058.103807390.22890-0.547006.946505.19510HepG2LARP7
HPENSG00000257017.42712.011607761.31230-1.5169038.9523035.38230HepG2LIN28B
HPENSG00000257017.412002.185906373.241200.9131016.6106015.07090HepG2MAGOH
HPENSG00000257017.47835.938406259.385600.324003.048301.35830HepG2MARK2
HPENSG00000257017.43029.632706408.73720-1.0809019.3129017.76510HepG2MATR3
HPENSG00000257017.43692.852805584.70450-0.596704.664303.31970HepG2METAP2
HPENSG00000257017.44381.336801723.136001.346207.317205.70550HepG2MTPAP
HPENSG00000257017.44091.194903061.511800.418204.056502.58700HepG2NAA15
HPENSG00000257017.411851.309506682.521600.8265017.8412014.71170HepG2NIP7
HPENSG00000257017.42339.411804052.93080-0.792807.922105.56570HepG2NKRF
HPENSG00000257017.46517.0826010181.68200-0.6437016.8872015.09710HepG2NOL12
HPENSG00000257017.44208.235105841.06280-0.473004.613303.69300HepG2PABPC4
HPENSG00000257017.44514.251707296.17820-0.6927026.8492024.74380HepG2PARN
HPENSG00000257017.411298.317506194.182900.8670046.6886044.76730HepG2PCBP1
HPENSG00000257017.446171.804309393.325002.2972053.4944049.72320HepG2PCBP2
HPENSG00000257017.41641.910204432.78480-1.4328018.1413014.62720HepG2PNPT1
HPENSG00000257017.42460.256304153.82690-0.755609.096205.75980HepG2PPIG
HPENSG00000257017.44552.160206574.54630-0.5303012.7899011.27130HepG2PPIL4
HPENSG00000257017.41488.668802205.51120-0.567102.798302.02130HepG2PRPF4
HPENSG00000257017.43271.290404786.69000-0.549206.096404.94810HepG2PRPF8
HPENSG00000257017.49754.871106302.982900.630003.849203.22720HepG2PTBP1
HPENSG00000257017.44778.2806010310.30660-1.1095043.2611040.90190HepG2PUM2
HPENSG00000257017.49609.221404342.894601.1457088.2874085.87150HepG2PUS1
HPENSG00000257017.41576.728406825.92330-2.11410149.62730146.39420HepG2QKI
HPENSG00000257017.46021.548609064.46080-0.590103.588502.78800HepG2RAVER1
HPENSG00000257017.43102.459102082.564300.575005.763003.12580HepG2RBM14
HPENSG00000257017.47210.084804773.640900.5948013.3799011.70860HepG2RBM15
HPENSG00000257017.4434.472503839.73870-3.1437047.6534046.01150HepG2RBM22
HPENSG00000257017.45966.923808911.21280-0.578607.492305.84530HepG2RBM27
HPENSG00000257017.42064.780704773.93100-1.2092016.9372013.65060HepG2RBM47
HPENSG00000257017.411442.040907236.278500.660909.623507.67870HepG2RCC2
HPENSG00000257017.410748.861307014.473400.6157024.2834022.99710HepG2NELFE
HPENSG00000257017.413528.036706533.285201.0500071.1414068.92640HepG2RECQL
HPENSG00000257017.417912.888404180.992802.09900103.35780100.78000HepG2RPLP0
HPENSG00000257017.44065.162205192.74800-0.353204.386503.63060HepG2RPS19
HPENSG00000257017.417714.315704962.103301.8358037.0578034.32200HepG2RPS3A
HPENSG00000257017.41336.801004735.07670-1.8246050.2204047.72240HepG2RRP9
HPENSG00000257017.46216.336809862.39730-0.665905.243003.13390HepG2RTF1
HPENSG00000257017.42393.744906564.37480-1.45540129.60640126.55120HepG2SAFB2
HPENSG00000257017.41342.406304672.73750-1.7994041.1877037.42460HepG2SART3
HPENSG00000257017.42687.506904714.90170-0.811006.803204.49900HepG2SBDS
HPENSG00000257017.48546.950703908.513901.128702.878102.19040HepG2SF3A3
HPENSG00000257017.410163.775306561.913500.6311014.7186013.52000HepG2SF3B4
HPENSG00000257017.47184.654209320.12710-0.3754011.7635010.48740HepG2SLBP
HPENSG00000257017.43422.893307655.09950-1.16120112.45380109.68790HepG2SMN1
HPENSG00000257017.46192.463408822.74810-0.510704.057402.09360HepG2SND1
HPENSG00000257017.48667.058401860.124202.220007.472106.17910HepG2SNRNP70
HPENSG00000257017.45390.414104336.992300.313603.147302.62490HepG2SRFBP1
HPENSG00000257017.419440.182109596.987601.0183035.0938033.21730HepG2SRSF5
HPENSG00000257017.49208.767203812.883101.2720036.9748035.02770HepG2SRSF7
HPENSG00000257017.420703.619905572.411601.89340241.49320238.35390HepG2SRSF9
HPENSG00000257017.419529.383703765.795802.37450121.24420119.22070HepG2SSB
HPENSG00000257017.41431.399303008.86890-1.0718013.2849010.85450HepG2STAU1
HPENSG00000257017.416725.083108471.041800.9813011.501409.19400HepG2SUB1
HPENSG00000257017.48626.1433010914.12340-0.339407.098406.18240HepG2SUCLG1
HPENSG00000257017.42380.611604314.22540-0.857805.383903.53610HepG2SUGP2
HPENSG00000257017.411005.980706176.521100.8333011.074609.87140HepG2SUPV3L1
HPENSG00000257017.437489.035706156.801002.60610118.87660115.89810HepG2TAF15
HPENSG00000257017.46629.933804185.424800.663503.226102.07540HepG2TBRG4
HPENSG00000257017.48329.152504139.994701.0084018.1052016.05510HepG2TFIP11
HPENSG00000257017.48679.469007162.271200.277103.536902.98600HepG2TIAL1
HPENSG00000257017.46273.219409102.15840-0.537004.002602.25060HepG2TRA2A
HPENSG00000257017.42297.457907226.58400-1.65330140.52940137.30300HepG2TRIM56
HPENSG00000257017.46207.966604240.121600.549905.009602.92720HepG2TROVE2
HPENSG00000257017.415104.548009496.061700.6695016.1554013.84600HepG2TUFM
HPENSG00000257017.41855.794203853.66560-1.0542022.7093020.84750HepG2U2AF1
HPENSG00000257017.45490.8160010051.74100-0.8724014.4651012.51960HepG2UBE2L3
HPENSG00000257017.41808.555603648.76100-1.0126018.6366016.70650HepG2UCHL5
HPENSG00000257017.46135.444903466.218700.823707.638606.57250HepG2UPF1
HPENSG00000257017.410388.436105656.187500.8770010.201608.21710HepG2UPF2
HPENSG00000257017.46792.933103563.054800.930804.875803.52300HepG2UTP18
HPENSG00000257017.45503.747503346.552400.717606.706405.84260HepG2UTP3
HPENSG00000257017.41455.033104444.46150-1.6110028.8908025.47990HepG2XPO5
HPENSG00000257017.46389.877708914.09860-0.480303.377801.96690HepG2XRCC5
HPENSG00000257017.44895.345809968.81790-1.0260012.8014010.71480HepG2XRCC6
HPENSG00000257017.44179.027006080.10330-0.540906.206305.13500HepG2XRN2
HPENSG00000257017.45559.193302176.402401.3528061.8607059.59240HepG2ZC3H8
HPENSG00000257017.42826.226209056.73130-1.6801034.0802030.31820HepG2ZRANB2
HPENSG00000257017.434.557701.648104.390106.713105.86350K562AQR
HPENSG00000257017.41.0491012.62730-3.589302.469201.70450K562MTPAP
HPENSG00000257017.41.8331014.02350-2.935502.293601.60820K562NSUN2
HPENSG00000257017.40.0000012.95030-99999.999993.857201.45260K562NUFIP2
HPENSG00000257017.42.0442013.84750-2.760002.309501.55890K562SF3A3
HPENSG00000257017.40.0000014.18790-99999.999994.341203.19610K562SRPK2
HPENSG00000257017.41.1709014.86990-3.666702.875202.14260K562UPF1
HPENSG00000257017.40.5021012.72280-4.663303.132002.20360K562WDR3
HPENSG00000257017.40.0000013.23620-99999.999994.142503.12230K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HP is not available on ENCORE database.





4 RBPs can affect the splicing of HP :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHPENSG00000257017.4chr16+7209042872090530720900597209014272092152720922540.142000.000940.04425includedHepG2SF3B4
SEHPENSG00000257017.4chr16+7209304172093087720912907209136572094010720949540.100000.000000.00070includedHepG2TAF15
A3SSHPENSG00000257017.4chr16+7209401072094954720945617209495472093041720930870.190000.000270.05578longerHepG2TAF15
A3SSHPENSG00000257017.4chr16+7209401072094954720945617209495472093012720930870.234000.001030.06945longerHepG2SF3B4
MXEHPENSG00000257017.4chr16+72090428720905307209215272092254720900597209014272093012720930870.119000.000770.086851includedHepG2HNRNPA1
MXEHPENSG00000257017.4chr16+72090428720905307209215272092254720900597209014272093012720930870.087000.003450.071201includedHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HP is not avaliable on ENCORE database.