PC

General Information

Gene Name       : PC
Gene ID             : ENSG00000173599.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PC)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PCENSG00000173599.130.292.851.57ENCSR000AEF
HepG2PCENSG00000173599.1343.5921.9432.77ENCSR985KAT
K562PCENSG00000173599.1314.999.2012.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PC is not avaliable on ENCORE database.



Proteins bound to RNA
  • PC RNA is bound by 25 proteins.  







eCLIP assay for PC is not avaliable on ENCORE database.





25 proteins are bound to PC RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116661604666616157-3'-UTR,intron-Distal4.4685410.73972HepG2UPF1
chr116661603666616150-3'-UTR,intron-Distal3.318145.85977HepG2GRSF1
chr116661626966616361-3'-UTR,intron-Distal,intron-Proximal4.704765.64948HepG2UPF1
chr116663835466638419-CDS,intron-Distal,intron-Proximal5.1531513.00415HepG2EFTUD2
chr116661990266619924-CDS,intron-Distal,intron-Proximal3.398693.59112HepG2PPIG
chr116661927766619313-CDS,intron-Distal3.660684.96634HepG2PPIG
chr116663847766638551-CDS,intron-Distal,intron-Proximal4.3493911.17766HepG2PRPF8
chr116661672566616750-CDS,intron-Distal,intron-Proximal4.217413.49905HepG2PPIG
chr116661845366618518-CDS,intron-Distal,intron-Proximal3.599385.70176HepG2AQR
chr116662029766620365-CDS,intron-Distal,intron-Proximal3.468006.65571HepG2SF3B4
chr116663847866638553-CDS,intron-Distal,intron-Proximal4.500729.49243HepG2EFTUD2
chr116663852566638551-CDS,intron-Distal3.144474.24993HepG2PPIG
chr116663138766631479-CDS,intron-Distal,intron-Proximal3.250825.37254HepG2SF3B4
chr116663819266638254-CDS,intron-Distal,intron-Proximal4.398277.99161HepG2PRPF8
chr116661874866618805-CDS,intron-Distal,intron-Proximal3.655785.55128HepG2SF3B4
chr116663780466637900-CDS,intron-Distal4.7128511.68917HepG2PPIG
chr116663930066639330-CDS,intron-Distal3.543453.59112HepG2PPIG
chr116661735666617416-CDS,intron-Distal,intron-Proximal3.525966.69747HepG2PRPF8
chr116661872966618803-CDS,intron-Distal,intron-Proximal4.993205.40008K562SF3B4
chr116663367566633698-CDS,intron-Distal3.223453.32039HepG2PPIG
chr116663773166637778-CDS,intron-Distal,intron-Proximal4.105796.79646HepG2PRPF8
chr116661763566617715-CDS,intron-Distal,intron-Proximal4.1964715.11890HepG2PRPF8
chr116661846266618516-CDS,intron-Distal,intron-Proximal3.825335.43815HepG2PRPF8
chr116663137366631463-CDS,intron-Distal,intron-Proximal4.363937.43248HepG2SF3A3
chr116663132766631384-CDS,intron-Distal4.067323.14999HepG2GRWD1
chr116663918566639233-CDS,intron-Distal4.349065.79466HepG2RPS3
chr116662148666621584-intron-Distal4.935968.13169HepG2PRPF4
chr116666305566663193-intron-Distal4.265743.27829HepG2MATR3
chr116662050166620694-intron-Distal,intron-Proximal4.3427713.34347HepG2DDX59
chr116665024966650308-intron-Distal3.411833.12080HepG2XPO5
chr116665358066653703-intron-Distal5.5950412.06030HepG2PCBP2
chr116662032266620419-intron-Distal,intron-Proximal3.120576.66333HepG2HNRNPK
chr116662866266628714-intron-Distal3.330674.68402HepG2CSTF2T
chr116662655566626619-intron-Distal4.248186.00449HepG2FAM120A
chr116662609366626155-intron-Distal3.660048.85479HepG2CSTF2T
chr116662414666624187-intron-Distal3.340806.28777HepG2CSTF2T
chr116665463566654701-intron-Distal4.309763.51329HepG2MATR3
chr116662486166624887-intron-Distal3.700135.80161HepG2CSTF2T
chr116662228766622337-intron-Distal4.445624.86859HepG2CSTF2T
chr116663117166631216-intron-Distal,intron-Proximal3.005976.44186HepG2RBM22
chr116662739566627467-intron-Distal4.164675.44474HepG2FAM120A
chr116662560066625671-intron-Distal4.395799.17322HepG2CSTF2T
chr116662970966629730-intron-Distal4.151513.87340HepG2CSTF2T
chr116662684966626908-intron-Distal5.7653314.40554HepG2CSTF2T
chr116662645966626499-intron-Distal3.269455.82968HepG2CSTF2T
chr116662163566621688-intron-Distal3.432454.35339HepG2CSTF2T
chr116662096266620994-intron-Distal3.866353.16310HepG2CSTF2T
chr116662569766625730-intron-Distal,intron-Proximal4.071483.42782HepG2NKRF
chr116664196166642048-intron-Distal4.625825.57752HepG2PTBP1
chr116662896466629008-intron-Distal3.084123.41531HepG2RBFOX2
chr116662478666624813-intron-Distal4.455355.36332HepG2CSTF2T
chr116662758066627630-intron-Distal3.844155.32871HepG2CSTF2T
chr116662061766620683-intron-Distal,intron-Proximal3.6461510.77057HepG2HNRNPK
chr116662523766625304-intron-Distal,intron-Proximal3.611959.78761HepG2CSTF2T
chr116663099366631048-intron-Distal3.849064.14792HepG2XPO5
chr116662053966620615-intron-Distal,intron-Proximal4.9798525.29358HepG2HNRNPK
chr116662685766626903-intron-Distal4.608423.77801HepG2FKBP4
chr116662770466627757-intron-Distal4.5243911.28783HepG2CSTF2T
chr116662547766625508-intron-Distal3.616315.32871HepG2CSTF2T
chr116661941766619515-intron-Distal,intron-Proximal4.087705.98968HepG2SF3B4
chr116662147766621562-intron-Distal3.854416.48652HepG2CSTF2T
chr116662049066620529-intron-Distal,intron-Proximal4.045744.12666HepG2HNRNPK
chr116662706366627159-intron-Distal4.1431812.85465HepG2CSTF2T
chr116663227666632360-intron-Distal4.320314.87774HepG2HNRNPK
chr116668727466687300-intron-Distal5.8112412.47021K562LSM11
chr116662444166624495-intron-Distal3.279337.93684HepG2CSTF2T
chr116667323166673334-intron-Distal3.903774.25134HepG2RBFOX2
chr116663306866633160-intron-Distal4.423164.36718HepG2NKRF
chr116663266366632717-intron-Distal3.125273.00221HepG2CSTF2T
chr116663759166637722-intron-Distal,intron-Proximal4.621897.61488HepG2EFTUD2
chr116662927266629327-intron-Distal3.634126.51348HepG2CSTF2T
chr116662505166625098-intron-Distal3.595408.27616HepG2CSTF2T
chr116662934666629409-intron-Distal4.615225.69834HepG2NKRF
chr116662987666629919-intron-Distal3.709244.14880HepG2CSTF2T
chr116668720066687274-intron-Distal6.2319315.99078K562LSM11
chr116666531466665380-intron-Distal4.260013.82973HepG2HLTF
chr116662721866627289-intron-Distal4.6046210.86370HepG2CSTF2T
chr116662576466625822-intron-Distal,intron-Proximal3.880387.44912HepG2CSTF2T
chr116662032366620405-intron-Distal,intron-Proximal3.510035.95859HepG2DDX59
chr116662491366624957-intron-Distal3.616315.62912HepG2CSTF2T
chr116662814466628190-intron-Distal4.857186.58550HepG2CSTF2T
chr116663306466633126-intron-Distal4.217134.10339HepG2CSTF2T
chr116662895566628964-intron-Distal4.165533.18939HepG2RBFOX2
chr116662217066622212-intron-Distal3.997563.40229HepG2CSTF2T
chr116662656666626646-intron-Distal3.6285710.41008HepG2CSTF2T
chr116662597966626059-intron-Distal4.6410011.63297HepG2CSTF2T
chr116662707966627126-intron-Distal3.643684.64721HepG2NKRF
chr116662126866621367-intron-Distal3.297605.43093HepG2CSTF2T
chr116661942266619500-intron-Distal,intron-Proximal4.845677.86715HepG2SF3A3
chr116666308066663186-intron-Distal5.233886.08961HepG2PTBP1
chr116663008966630131-intron-Distal3.297605.36249HepG2CSTF2T
chr116661733066617390-intron-Distal,intron-Proximal6.088339.61799HepG2EFTUD2
chr116662536566625415-intron-Distal3.429117.23670HepG2CSTF2T
chr116662615566626212-intron-Distal3.914129.58042HepG2CSTF2T
chr116662221266622270-intron-Distal3.429114.45183HepG2CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PC is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PC is not available on ENCORE database.

  • 109 RBPs can affect the levels of PC.  








The Knockdown/knockout RNA-Seq assay for PC is not available on ENCORE database.





109 RBPs can affect the gene expression of PC :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PCENSG00000173599.91452.182901670.26670-0.201902.148801.59850HepG2ACO1
PCENSG00000173599.9814.452602701.11390-1.729705.564204.84080HepG2AKAP1
PCENSG00000173599.92295.838001677.952000.452208.604107.34590HepG2AKAP8L
PCENSG00000173599.91292.49680858.282500.590504.384903.27680HepG2BCLAF1
PCENSG00000173599.91574.938001090.165300.530603.464102.09400HepG2BUD13
PCENSG00000173599.9532.93930804.72860-0.594502.022901.37440HepG2CNOT7
PCENSG00000173599.91312.66140708.451900.889708.540107.38890HepG2CPSF6
PCENSG00000173599.91881.476501198.179200.650902.602301.52970HepG2CPSF7
PCENSG00000173599.9968.17850718.234600.430703.736902.55040HepG2YBX3
PCENSG00000173599.92069.701201251.599300.7255017.5095016.16920HepG2CELF1
PCENSG00000173599.92171.699901345.831400.6902021.7789020.06080HepG2DAZAP1
PCENSG00000173599.91957.72990971.411001.0109012.1309010.65150HepG2DDX55
PCENSG00000173599.91567.884201113.029100.494204.883403.56500HepG2DDX5
PCENSG00000173599.91129.90210705.160300.680108.420307.24640HepG2DNAJC21
PCENSG00000173599.91144.81010699.067600.7115012.9017011.60420HepG2DNAJC2
PCENSG00000173599.92720.533001271.858201.0969023.1499021.02300HepG2EIF4G2
PCENSG00000173599.9833.795301260.65960-0.596403.109901.95420HepG2ESF1
PCENSG00000173599.91562.688602493.24410-0.6740012.0492010.93830HepG2ETF1
PCENSG00000173599.91074.565501631.97600-0.602905.408104.24060HepG2EWSR1
PCENSG00000173599.9815.09400577.574700.496904.034501.59380HepG2EXOSC5
PCENSG00000173599.9666.152901636.38200-1.2966023.3261021.15170HepG2FUBP3
PCENSG00000173599.91627.81380916.918400.828003.945902.72600HepG2GNB2L1
PCENSG00000173599.91677.35610802.972201.062709.657808.51040HepG2GPKOW
PCENSG00000173599.91134.23250681.269200.735305.454003.45840HepG2HNRNPA0
PCENSG00000173599.9374.39670711.91750-0.927103.619402.89400HepG2HNRNPA1
PCENSG00000173599.91931.466901236.831100.642903.338302.32370HepG2HNRNPA2B1
PCENSG00000173599.91796.51870858.570301.0651035.9779033.89780HepG2HNRNPF
PCENSG00000173599.9530.761402240.10950-2.077406.747605.69290HepG2HNRNPK
PCENSG00000173599.91556.897401225.966100.344705.275904.37050HepG2HNRNPL
PCENSG00000173599.91019.99170766.301400.412502.121801.56290HepG2HNRNPLL
PCENSG00000173599.91372.92540786.682000.803305.024004.22750HepG2HNRNPU
PCENSG00000173599.91721.06840845.450901.0254023.4049021.54980HepG2IGF2BP1
PCENSG00000173599.93313.739002245.746200.561202.589901.93490HepG2IGF2BP2
PCENSG00000173599.91873.448201334.520700.489307.089305.87850HepG2NOL12
PCENSG00000173599.91019.61860601.839000.760505.211603.26720HepG2NOLC1
PCENSG00000173599.91522.07070892.392100.770203.912102.59700HepG2NONO
PCENSG00000173599.91050.91550735.770700.514202.423901.60370HepG2PABPC1
PCENSG00000173599.9684.381001059.86530-0.6310010.324408.96690HepG2PRPF4
PCENSG00000173599.91114.49030748.955700.573302.408201.65310HepG2PRPF8
PCENSG00000173599.92357.118201273.901600.8877017.7486016.41740HepG2PUF60
PCENSG00000173599.92027.726301352.284800.5844016.3955015.19900HepG2PUM1
PCENSG00000173599.9861.326201351.30820-0.649709.881708.65590HepG2PUM2
PCENSG00000173599.91732.874302445.00640-0.496703.629602.92840HepG2QKI
PCENSG00000173599.92006.613401687.539400.249702.211301.43460HepG2RBM15
PCENSG00000173599.9604.881302083.85710-1.7845050.6483048.97170HepG2RBM22
PCENSG00000173599.91996.139102512.72080-0.332002.279001.77830HepG2NELFE
PCENSG00000173599.91735.527102340.54600-0.431503.276902.61320HepG2RECQL
PCENSG00000173599.91270.15410924.828000.457602.685602.01020HepG2RPLP0
PCENSG00000173599.9434.38790834.65590-0.942205.211204.39820HepG2RPS19
PCENSG00000173599.91497.80370808.831800.888808.807907.40940HepG2RPS3A
PCENSG00000173599.91113.67860700.548900.6687011.1825010.02410HepG2SAFB2
PCENSG00000173599.91077.187801549.28770-0.524303.308902.56980HepG2SF3A3
PCENSG00000173599.91774.324102350.47290-0.405703.389602.74340HepG2SF3B4
PCENSG00000173599.91739.35640914.136900.928004.701203.42200HepG2SMNDC1
PCENSG00000173599.91349.110802353.58050-0.8028022.0851021.02310HepG2SRFBP1
PCENSG00000173599.91946.365202453.52470-0.334102.432001.98120HepG2SRSF1
PCENSG00000173599.91533.652501257.770800.286003.286602.61410HepG2SRSF5
PCENSG00000173599.91546.56040843.502500.8745023.9269022.27450HepG2SRSF7
PCENSG00000173599.91607.252901996.19350-0.312701.949201.47060HepG2SRSF9
PCENSG00000173599.91525.18440981.175300.636304.767203.18620HepG2STAU1
PCENSG00000173599.91755.979801430.450300.295704.067303.33830HepG2SUCLG1
PCENSG00000173599.9890.132102205.71180-1.3092014.1678013.04470HepG2TAF15
PCENSG00000173599.91532.713402026.33680-0.402802.932702.07340HepG2TIA1
PCENSG00000173599.91455.58440771.252600.9162025.3557023.86230HepG2TRIM56
PCENSG00000173599.9706.261501257.02150-0.831704.390203.60710HepG2U2AF1
PCENSG00000173599.9381.61460571.10000-0.581603.990003.07880HepG2UCHL5
PCENSG00000173599.92302.256901373.982600.7446011.4594010.21520HepG2UPF1
PCENSG00000173599.91734.837901412.252400.296703.502402.33950HepG2UTP18
PCENSG00000173599.91007.38560724.515100.475402.485301.45340HepG2XPO5
PCENSG00000173599.9901.670101045.96930-0.214201.936301.35890HepG2ZC3H8
PCENSG00000173599.92221.396201511.116000.5558016.1508015.10280HepG2ZNF622
PCENSG00000173599.9287.29360457.92340-0.672606.076305.28660K562AGGF1
PCENSG00000173599.9241.69040605.23150-1.3243014.7426013.53780K562AQR
PCENSG00000173599.996.89440160.11660-0.724602.633101.78280K562BOP1
PCENSG00000173599.9393.87010547.25620-0.474503.707802.31510K562CCDC124
PCENSG00000173599.9322.24120443.30460-0.460203.256702.04980K562CPEB4
PCENSG00000173599.9394.35150809.45590-1.0375016.8174014.59910K562CELF1
PCENSG00000173599.9150.02840251.91760-0.747703.078402.11330K562EFTUD2
PCENSG00000173599.9195.17350129.418300.592602.544101.78050K562EIF3G
PCENSG00000173599.9143.70150338.39020-1.235609.540608.00580K562EIF4A3
PCENSG00000173599.9524.84320658.15770-0.326502.728201.79620K562EIF4G2
PCENSG00000173599.9122.55350210.86310-0.782903.062001.86180K562FKBP4
PCENSG00000173599.9110.35170173.23660-0.650602.422001.61950K562FMR1
PCENSG00000173599.994.33760146.84410-0.638402.159001.35610K562FTO
PCENSG00000173599.98.2768075.62950-3.191806.165905.01860K562G3BP2
PCENSG00000173599.945.24350209.04700-2.2080011.330708.81560K562HNRNPK
PCENSG00000173599.9286.16970414.59140-0.534803.587502.36320K562HNRNPL
PCENSG00000173599.9441.27940331.040300.414602.162301.45650K562HSPD1
PCENSG00000173599.9339.86150209.572100.697402.504601.54460K562IGF2BP2
PCENSG00000173599.9183.44870354.21480-0.949204.714502.82150K562ILF2
PCENSG00000173599.971.23730138.80210-0.962303.234402.21740K562KRR1
PCENSG00000173599.9488.20970701.49780-0.522904.446003.01220K562MSI2
PCENSG00000173599.9277.83760397.06900-0.515102.242101.46840K562NAA15
PCENSG00000173599.9480.56830719.99050-0.583203.440501.75700K562NOL12
PCENSG00000173599.9247.95480372.85030-0.588502.474201.32250K562PABPC1
PCENSG00000173599.9100.73930195.73830-0.958303.939902.76730K562PCBP2
PCENSG00000173599.9255.66580401.10880-0.649702.574701.77340K562PCBP3
PCENSG00000173599.9216.68180307.65240-0.505702.737601.94120K562POLR2G
PCENSG00000173599.9205.95160345.25850-0.745403.564601.49880K562PPIL4
PCENSG00000173599.9386.82150213.795000.855307.351106.30620K562PTBP1
PCENSG00000173599.9422.86770718.07320-0.763907.811306.43410K562PUF60
PCENSG00000173599.9477.18920763.97130-0.679008.345606.40940K562PUM1
PCENSG00000173599.9489.32050748.34900-0.612907.452205.85690K562PUM2
PCENSG00000173599.9365.23570460.42650-0.334101.885601.37910K562RBM15
PCENSG00000173599.9324.21290199.815000.698202.811801.42380K562RBM34
PCENSG00000173599.9197.85810406.99670-1.040604.093402.12210K562RBM39
PCENSG00000173599.9146.38130249.62500-0.770002.706001.89940K562RPS19
PCENSG00000173599.9283.68340464.76830-0.712206.968705.72010K562SF3A3
PCENSG00000173599.962.26050154.60320-1.312205.808604.36580K562SF3B1
PCENSG00000173599.9146.53260265.45830-0.857305.335303.55010K562SLBP
PCENSG00000173599.9141.37500347.39450-1.297006.054304.00970K562SNRNP200
PCENSG00000173599.9301.27420476.16860-0.660406.574105.19990K562SRPK2
PCENSG00000173599.9304.34500209.614600.537902.459601.78620K562SRSF1
PCENSG00000173599.9311.32550198.025200.652602.722401.68350K562SRSF5
PCENSG00000173599.9215.53540320.36330-0.571802.970401.55710K562SSRP1
PCENSG00000173599.9198.77840293.00610-0.559802.631401.41900K562STAU1
PCENSG00000173599.9466.36400626.51270-0.425903.399801.73660K562SUCLG1
PCENSG00000173599.9209.27640415.63890-0.989903.928102.10820K562SUPT6H
PCENSG00000173599.9152.82500237.20280-0.634202.668101.66960K562SUPV3L1
PCENSG00000173599.9314.95650204.599900.622202.491801.72100K562TIA1
PCENSG00000173599.9304.61620200.896900.600403.260302.05700K562TRA2A
PCENSG00000173599.917.6119073.13990-2.054104.281302.85960K562U2AF1
PCENSG00000173599.96.6460075.59310-3.507707.168205.88270K562U2AF2
PCENSG00000173599.9609.61580809.76840-0.409602.875901.44360K562UBE2L3
PCENSG00000173599.9312.27810499.38480-0.677307.022305.93660K562UPF1
PCENSG00000173599.9169.54370382.55250-1.174004.721503.14490K562UTP3
PCENSG00000173599.9507.63130716.91570-0.498004.291402.67310K562WRN
PCENSG00000173599.9205.14910408.93660-0.995204.050401.95420K562YTHDC2
PCENSG00000173599.9466.19390681.89820-0.548603.262002.31540K562ZC3H8
PCENSG00000173599.9177.75240382.52720-1.105704.826101.71740K562ZRANB2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PC is not available on ENCORE database.





4 RBPs can affect the splicing of PC :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPCENSG00000173599.9chr11-666207096662085466620217666203076663124466631427-0.161000.000000.00001excludedHepG2U2AF1
SEPCENSG00000173599.9chr11-666207096662085466620217666203076663124466631427-0.389000.000000.00000excludedHepG2HNRNPK
SEPCENSG00000173599.9chr11-666207096662085466620217666203076663124466631427-0.084000.002560.03088excludedHepG2U2AF2
A3SSPCENSG00000173599.9chr11-666192606661941766619260666193226661990966620109-0.165000.000000.00353shorterHepG2SRSF9

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PC is not avaliable on ENCORE database.