PIN1

General Information

Gene Name       : PIN1
Gene ID             : ENSG00000127445.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PIN1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PIN1ENSG00000127445.133.3410.877.10ENCSR000AEF
HepG2PIN1ENSG00000127445.1352.808.4330.61ENCSR985KAT
K562PIN1ENSG00000127445.1342.0513.1927.62ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PIN1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PIN1 RNA is bound by 18 proteins.  







eCLIP assay for PIN1 is not avaliable on ENCORE database.





18 proteins are bound to PIN1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1999600649960209+3'-UTR,intron-Distal,intron-Proximal4.683295.32242HepG2PABPN1
chr1999600979960166+3'-UTR,intron-Distal,intron-Proximal3.511687.19915K562UPF1
chr1999588149958837+3'-UTR,CDS,intron-Proximal4.442345.97994K562AQR
chr1999601049960149+3'-UTR,intron-Distal,intron-Proximal4.286356.92152K562PABPC4
chr1999588639958904+3'-UTR,CDS,intron-Proximal4.842335.26064K562AQR
chr1999601669960235+3'-UTR,intron-Proximal4.252896.74636K562UPF1
chr1999600039960142+3'-UTR,intron-Distal,intron-Proximal3.980303.79347HepG2GRWD1
chr1999598609959958+3'-UTR,CDS,intron-Proximal4.206403.95192HepG2UPF1
chr1999601499960234+3'-UTR,intron-Proximal5.5395314.93866K562PABPC4
chr1999599919960041+3'-UTR,intron-Distal,intron-Proximal5.113767.86232HepG2LARP4
chr1999601529960217+3'-UTR,intron-Proximal3.345465.36775K562DDX6
chr1999600759960227+3'-UTR,intron-Distal,intron-Proximal4.020509.61870K562DDX55
chr1999602399960287+3'-UTR3.188023.35294K562PABPC4
chr1999586329958782+3'-UTR,CDS,intron-Proximal3.546524.10684HepG2AQR
chr1999601779960240+3'-UTR,intron-Proximal4.261714.12150K562LSM11
chr1999601119960226+3'-UTR,intron-Proximal4.767536.45671HepG2UPF1
chr1999460069946085+5'-UTR,CDS,intron-Proximal4.026863.79347HepG2GRWD1
chr1999491779949264+5'-UTR,CDS3.321883.01092HepG2LIN28B
chr1999460009946079+5'-UTR,CDS,intron-Proximal3.282015.17903K562UCHL5
chr1999460099946050+5'-UTR,CDS3.679564.82082K562ZNF622
chr1999491119949178+5'-UTR,CDS,intron-Proximal3.064048.03396K562YBX3
chr1999491799949252+5'-UTR,CDS4.599346.40168K562LIN28B
chr1999493119949380+5'-UTR,CDS,intron-Proximal5.192247.70650HepG2PRPF8
chr1999491949949325+5'-UTR,CDS,intron-Proximal4.634046.03393K562YBX3
chr1999460509946080+CDS,intron-Proximal3.393415.23038K562ZNF622
chr1999460609946165+CDS,intron-Proximal3.302234.50321HepG2PRPF8
chr1999588379958863+CDS,intron-Proximal5.842339.95272K562AQR
chr1999550639955093+intron-Distal4.578507.91405K562EXOSC5
chr1999463029946383+intron-Distal6.8275720.00279HepG2XPO5
chr1999463839946485+intron-Distal4.3811310.01505HepG2XPO5
chr1999490059949097+intron-Distal,intron-Proximal6.080415.12752HepG2SF3A3
chr1999585369958648+intron-Distal,intron-Proximal5.475929.37109K562EIF4G2
chr1999583869958452+intron-Distal4.279766.26655K562EIF4G2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PIN1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PIN1 is not available on ENCORE database.

  • 98 RBPs can affect the levels of PIN1.  








The Knockdown/knockout RNA-Seq assay for PIN1 is not available on ENCORE database.





98 RBPs can affect the gene expression of PIN1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PIN1ENSG00000127445.9180.78910346.46120-0.938406.596405.40870HepG2ASCC1
PIN1ENSG00000127445.9397.39170506.14330-0.349002.645401.99120HepG2CKAP4
PIN1ENSG00000127445.9270.97200168.697600.683602.638101.89190HepG2CNOT7
PIN1ENSG00000127445.9460.24430340.961500.432703.349002.65560HepG2CELF1
PIN1ENSG00000127445.9845.56070401.082701.075907.718106.72110HepG2DDX3X
PIN1ENSG00000127445.9479.11290344.670200.475002.359901.78590HepG2DDX6
PIN1ENSG00000127445.9248.41520165.275300.587803.267602.50780HepG2DNAJC21
PIN1ENSG00000127445.9310.17650163.816800.920909.029907.93210HepG2DNAJC2
PIN1ENSG00000127445.9498.19130331.208900.588903.697403.01840HepG2EIF2S1
PIN1ENSG00000127445.9478.90560657.37530-0.457003.915703.22150HepG2ETF1
PIN1ENSG00000127445.9222.42980369.43410-0.732005.095204.04050HepG2FUBP3
PIN1ENSG00000127445.9606.33880369.431400.714702.270201.64110HepG2FXR1
PIN1ENSG00000127445.9226.66220142.713200.667302.744601.38190HepG2HNRNPA0
PIN1ENSG00000127445.9219.65660139.354900.656402.757601.35850HepG2HNRNPAB
PIN1ENSG00000127445.9578.86780347.149800.737606.068205.06300HepG2HNRNPK
PIN1ENSG00000127445.9469.17010333.881000.490704.520803.67600HepG2HNRNPL
PIN1ENSG00000127445.9385.20110270.297900.511002.559301.94960HepG2HNRNPLL
PIN1ENSG00000127445.9477.54310348.210600.455602.417901.78190HepG2IGF2BP2
PIN1ENSG00000127445.9243.94220160.807600.601102.525001.40000HepG2KHDRBS1
PIN1ENSG00000127445.9309.71150211.637600.549202.739201.61080HepG2LARP7
PIN1ENSG00000127445.9319.01460222.189300.521702.495001.34880HepG2LIN28B
PIN1ENSG00000127445.9628.25570369.561200.765405.525804.60800HepG2MAGOH
PIN1ENSG00000127445.9509.74300371.598400.455902.235301.66440HepG2MATR3
PIN1ENSG00000127445.9239.11910336.14110-0.491302.914301.66610HepG2NAA15
PIN1ENSG00000127445.9670.06580380.326300.817007.050706.06230HepG2NCBP2
PIN1ENSG00000127445.9281.82320191.358500.558402.750301.33780HepG2NIP7
PIN1ENSG00000127445.9509.53690363.475700.487204.044903.12300HepG2NOL12
PIN1ENSG00000127445.9251.60220117.673201.096305.587403.57740HepG2NOLC1
PIN1ENSG00000127445.9147.87050239.69040-0.696803.002702.22400HepG2NSUN2
PIN1ENSG00000127445.9264.46820164.445600.685403.084102.30930HepG2PPIL4
PIN1ENSG00000127445.9555.98860374.803800.568805.153604.45510HepG2PTBP1
PIN1ENSG00000127445.9482.06620346.987500.474203.170302.53840HepG2PUF60
PIN1ENSG00000127445.9534.73170368.363700.537606.023705.21770HepG2PUM1
PIN1ENSG00000127445.9700.66280515.655800.442204.666003.90680HepG2PUS1
PIN1ENSG00000127445.9349.54680493.24380-0.496803.712002.73540HepG2RBM15
PIN1ENSG00000127445.9401.53100255.204100.653803.745602.58070HepG2RBM27
PIN1ENSG00000127445.9630.55910417.114600.596106.053405.30470HepG2NELFE
PIN1ENSG00000127445.9310.75900200.803400.629902.342401.77140HepG2RPS19
PIN1ENSG00000127445.9387.83870235.359700.720504.487003.48160HepG2RPS2
PIN1ENSG00000127445.9278.80060169.458100.718203.365802.48380HepG2RPS3A
PIN1ENSG00000127445.9369.04700240.257800.619103.402502.20780HepG2RPS5
PIN1ENSG00000127445.9247.71570159.572600.634402.737901.43430HepG2SART3
PIN1ENSG00000127445.9281.21820191.475100.554403.443602.73870HepG2SMN1
PIN1ENSG00000127445.9363.36770218.885000.731202.872701.89670HepG2SMNDC1
PIN1ENSG00000127445.9471.24120620.57000-0.397103.396102.85870HepG2SRFBP1
PIN1ENSG00000127445.9433.28210342.625000.338602.272001.69790HepG2SRSF5
PIN1ENSG00000127445.9200.42150331.36160-0.725406.020305.26250HepG2SRSF9
PIN1ENSG00000127445.9648.48390538.794400.267201.897401.45210HepG2SSB
PIN1ENSG00000127445.9238.48200147.430500.693703.289902.08090HepG2STIP1
PIN1ENSG00000127445.9523.23130389.637300.425203.823403.11370HepG2SUCLG1
PIN1ENSG00000127445.9450.45550333.942200.431702.498801.60240HepG2SUPT6H
PIN1ENSG00000127445.9185.93970366.10820-0.977405.799305.03860HepG2TAF15
PIN1ENSG00000127445.9254.56450336.38810-0.402102.107801.37600HepG2TIA1
PIN1ENSG00000127445.9294.87020180.754100.706004.760604.06130HepG2TRIM56
PIN1ENSG00000127445.9483.64800339.026700.512503.737002.70750HepG2TUFM
PIN1ENSG00000127445.9308.01010423.14380-0.458202.538801.93470HepG2U2AF1
PIN1ENSG00000127445.9265.89890156.054100.768702.238401.55570HepG2UCHL5
PIN1ENSG00000127445.9466.51000378.825100.300301.872701.35930HepG2UTP3
PIN1ENSG00000127445.9282.72580151.787300.897305.094203.59180HepG2XPO5
PIN1ENSG00000127445.9560.89570431.540300.378103.318202.73550HepG2ZNF622
PIN1ENSG00000127445.91425.54970813.421100.8093019.3213017.93830K562AGGF1
PIN1ENSG00000127445.91279.56360893.862600.517404.811803.42740K562AKAP8
PIN1ENSG00000127445.91447.86800846.410300.774404.220303.41070K562AKAP8L
PIN1ENSG00000127445.9713.311501137.26310-0.673006.503005.66540K562AQR
PIN1ENSG00000127445.91090.12230888.104800.295602.757201.84540K562ATP5C1
PIN1ENSG00000127445.9552.03970393.390200.488704.140302.95090K562BCLAF1
PIN1ENSG00000127445.9469.79080298.445100.654505.399703.84560K562CSTF2
PIN1ENSG00000127445.91096.036501363.50210-0.315002.335001.43940K562CELF1
PIN1ENSG00000127445.9449.40170344.900900.381702.592501.31410K562DDX27
PIN1ENSG00000127445.9718.04860552.337000.378402.806201.75690K562DDX3X
PIN1ENSG00000127445.9980.23650708.592700.468106.070405.15740K562DDX47
PIN1ENSG00000127445.9715.97780559.987600.354402.843501.51060K562DDX6
PIN1ENSG00000127445.9504.04270333.296700.596602.718101.45170K562EEF2
PIN1ENSG00000127445.9444.77930321.975300.466002.441901.58630K562EFTUD2
PIN1ENSG00000127445.9315.44140211.690900.575303.611902.71090K562EIF3G
PIN1ENSG00000127445.9739.45440435.553300.763508.272506.71930K562FIP1L1
PIN1ENSG00000127445.9219.80850324.62760-0.562502.898302.02280K562FMR1
PIN1ENSG00000127445.949.24810168.65570-1.7759010.447908.90390K562G3BP2
PIN1ENSG00000127445.91240.64410926.911500.420503.921603.02560K562GRSF1
PIN1ENSG00000127445.9264.88050352.33060-0.411602.020401.49960K562HNRNPC
PIN1ENSG00000127445.9531.49390358.274900.568903.183902.18060K562HNRNPM
PIN1ENSG00000127445.9620.59110313.621000.984503.936002.62380K562IGF2BP2
PIN1ENSG00000127445.91147.90420898.222000.353802.761701.93690K562KIF1C
PIN1ENSG00000127445.9143.18750260.10590-0.861204.141202.97720K562KRR1
PIN1ENSG00000127445.9505.63490357.554900.499802.865101.38270K562LIN28B
PIN1ENSG00000127445.9510.65510329.384500.632505.243004.07680K562MAGOH
PIN1ENSG00000127445.91229.66830859.844500.516004.081802.69760K562MAK16
PIN1ENSG00000127445.91267.589101006.239800.333003.060202.09470K562MBNL1
PIN1ENSG00000127445.9468.31590317.476500.560703.195301.77750K562NONO
PIN1ENSG00000127445.9736.66360863.09040-0.228502.051101.39710K562NSUN2
PIN1ENSG00000127445.9498.85010347.056000.523302.761601.34750K562NUSAP1
PIN1ENSG00000127445.9297.66190515.69630-0.792804.695303.05450K562PABPC1
PIN1ENSG00000127445.9946.51080550.076100.782903.926802.69150K562PABPN1
PIN1ENSG00000127445.9875.90840494.476700.824805.363004.16010K562PPIG
PIN1ENSG00000127445.9444.99580313.321400.506002.661801.92620K562PRPF8
PIN1ENSG00000127445.9646.39070320.034001.0141014.4707013.01620K562PTBP1
PIN1ENSG00000127445.9837.832701286.87340-0.619106.388104.71110K562PUM1
PIN1ENSG00000127445.91636.87710839.343900.9635016.4615015.17600K562PUS1
PIN1ENSG00000127445.91250.61560817.866300.612609.444108.37200K562RBM15
PIN1ENSG00000127445.9393.87300288.377600.449702.411001.48960K562RCC2
PIN1ENSG00000127445.9567.16790319.086100.829706.060504.84750K562RPS19
PIN1ENSG00000127445.9419.33830241.928000.793404.905503.52640K562RPS3
PIN1ENSG00000127445.9636.28910851.61760-0.420504.518803.49750K562SF3A3
PIN1ENSG00000127445.9185.67680289.69470-0.641702.932701.93000K562SF3B1
PIN1ENSG00000127445.9429.31210273.360400.651104.472603.08250K562SRFBP1
PIN1ENSG00000127445.9644.38240313.764601.038106.943205.83300K562SRSF1
PIN1ENSG00000127445.9420.29860233.514200.847806.630204.87960K562SRSF4
PIN1ENSG00000127445.9522.21320296.387800.817107.785505.91890K562SRSF5
PIN1ENSG00000127445.9647.68720317.497301.0285012.2500010.57350K562TARDBP
PIN1ENSG00000127445.9629.17340306.275901.0385013.0917011.19200K562TIA1
PIN1ENSG00000127445.9477.35240300.673100.666802.456501.44050K562TRA2A
PIN1ENSG00000127445.9233.96150168.723100.471502.099401.40070K562U2AF2
PIN1ENSG00000127445.9998.601601364.00100-0.449904.215202.48360K562UBE2L3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PIN1 is not available on ENCORE database.





10 RBPs can affect the splicing of PIN1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPIN1ENSG00000127445.9chr19+9947319994755199459989946078994911199493240.068000.000220.01121includedK562PRPF8
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.096000.001130.02287includedHepG2U2AF1
SEPIN1ENSG00000127445.9chr19+9947333994755199459989946078994911199493240.084000.000110.01690includedHepG2DDX59
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.265000.000000.00000includedHepG2U2AF2
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.072000.001170.05735includedK562EFTUD2
SEPIN1ENSG00000127445.9chr19+994749899475519946044994607899491119949324-0.081000.000000.00037excludedK562EXOSC5
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.397000.000030.00109includedK562U2AF1
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.381000.000340.00811includedK562U2AF2
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.087000.000470.02113includedK562TARDBP
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.097000.000740.03576includedK562HNRNPK
SEPIN1ENSG00000127445.9chr19+9947498994755199460449946078994911199493240.081000.000910.03747includedK562PTBP1
RIPIN1ENSG00000127445.9chr19+995976599603589959765995987799602089960358-0.201000.002410.05103excludedHepG2FTO

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PIN1 is not avaliable on ENCORE database.