HSPE1

General Information

Gene Name       : HSPE1
Gene ID             : ENSG00000115541.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: HSPE1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HSPE1ENSG00000115541.10417.21339.00378.11ENCSR000AEF
HepG2HSPE1ENSG00000115541.10971.131276.041123.59ENCSR985KAT
K562HSPE1ENSG00000115541.10502.11385.75443.93ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HSPE1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HSPE1 RNA is bound by 19 proteins.  







eCLIP assay for HSPE1 is not avaliable on ENCORE database.





19 proteins are bound to HSPE1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2198367919198367982+3'-UTR,CDS,intron-Distal,intron-Proximal3.5111625.70686HepG2U2AF2
chr2198367930198368046+3'-UTR,CDS,intron-Distal,intron-Proximal3.3056010.42445HepG2DDX55
chr2198368113198368187+3'-UTR,intron-Distal,polyA_site4.858889.04223HepG2CSTF2
chr2198368009198368080+3'-UTR,intron-Distal5.48087400.00000K562PUM2
chr2198367991198368072+3'-UTR,intron-Distal3.9174334.54826HepG2LARP4
chr2198367932198367986+3'-UTR,CDS,intron-Distal,intron-Proximal3.0766722.45049HepG2LARP4
chr2198365076198365122+5'-UTR4.0600129.10843K562DDX3X
chr2198365134198365201+5'-UTR,CDS,intron-Proximal3.942183.09957HepG2AQR
chr2198364975198365022+5'-UTR4.4922710.43313HepG2DDX3X
chr2198365142198365154+5'-UTR4.8402661.22424HepG2PRPF8
chr2198365072198365107+5'-UTR3.6283412.61273HepG2DDX3X
chr2198365144198365163+5'-UTR,CDS3.291993.37451K562APOBEC3C
chr2198365090198365163+5'-UTR,CDS3.453525.73961K562GEMIN5
chr2198365007198365059+5'-UTR4.340964.00551K562DROSHA
chr2198365154198365176+5'-UTR,CDS,intron-Proximal4.8224276.12371HepG2PRPF8
chr2198365022198365072+5'-UTR6.2651018.41043HepG2DDX3X
chr2198365022198365123+5'-UTR3.209705.50955K562RPS3
chr2198364919198365022+5'-UTR3.643487.08819K562GEMIN5
chr2198365122198365165+5'-UTR,CDS,intron-Proximal3.6744344.95538K562DDX3X
chr2198365948198366040+CDS,intron-Distal,intron-Proximal5.253766.23935HepG2AQR
chr2198367696198367792+CDS,intron-Distal,intron-Proximal5.442187.90091HepG2AQR
chr2198367819198367854+CDS,intron-Distal,intron-Proximal4.391426.29269K562DDX6
chr2198365313198365393+intron-Distal3.989368.51983HepG2EFTUD2
chr2198366098198366198+intron-Distal4.573486.28383K562KHSRP
chr2198365249198365313+intron-Distal,intron-Proximal7.0102723.09021HepG2EFTUD2
chr2198366001198366142+intron-Distal,intron-Proximal3.408409.62297HepG2KHSRP
chr2198365231198365305+intron-Distal,intron-Proximal3.059073.31456K562TIA1
chr2198365213198365294+intron-Distal,intron-Proximal4.427074.15622HepG2TIAL1
chr2198365564198365620+intron-Distal4.000723.80990HepG2SRSF1
chr2198365648198365717+intron-Distal,intron-Proximal3.283306.39618K562KHSRP
chr2198365996198366074+intron-Distal,intron-Proximal3.293724.31340HepG2RBM22
chr2198365176198365206+intron-Proximal5.3596365.24818HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HSPE1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HSPE1 is not available on ENCORE database.

  • 136 RBPs can affect the levels of HSPE1.  








The Knockdown/knockout RNA-Seq assay for HSPE1 is not available on ENCORE database.





136 RBPs can affect the gene expression of HSPE1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HSPE1ENSG00000115541.64498.763605530.77610-0.298006.359305.51550HepG2ACO1
HSPE1ENSG00000115541.67008.984608866.61650-0.339207.603406.55590HepG2AUH
HSPE1ENSG00000115541.63777.454906015.92340-0.671404.676103.53250HepG2BCLAF1
HSPE1ENSG00000115541.63239.639904680.07470-0.530707.773505.81060HepG2BUD13
HSPE1ENSG00000115541.63948.516906514.46470-0.7223012.7306011.37710HepG2CPSF6
HSPE1ENSG00000115541.67712.742509052.76690-0.231103.274902.58740HepG2CELF1
HSPE1ENSG00000115541.67552.732209733.61280-0.3660011.8984010.53620HepG2DAZAP1
HSPE1ENSG00000115541.64348.376507397.69740-0.766605.472604.11280HepG2DDX59
HSPE1ENSG00000115541.64968.462606119.96950-0.300701.961301.43330HepG2DDX6
HSPE1ENSG00000115541.63356.738004782.45210-0.5107011.6867010.32350HepG2DNAJC21
HSPE1ENSG00000115541.63251.914204740.58880-0.5438011.3697010.14720HepG2DNAJC2
HSPE1ENSG00000115541.63598.475104551.34900-0.338902.915701.97160HepG2EEF2
HSPE1ENSG00000115541.63805.750705100.28170-0.422403.076501.90010HepG2AGO1
HSPE1ENSG00000115541.63569.222805884.23310-0.721208.585607.57770HepG2EIF2S1
HSPE1ENSG00000115541.62989.588603694.58960-0.305502.114901.31670HepG2EIF3D
HSPE1ENSG00000115541.68136.640309603.09440-0.239103.915002.94960HepG2EIF4G1
HSPE1ENSG00000115541.67120.037709199.09820-0.369603.250102.37150HepG2EIF4G2
HSPE1ENSG00000115541.65580.3235010180.16960-0.8673043.7374041.89370HepG2ETF1
HSPE1ENSG00000115541.66421.604105404.467600.248702.398901.62250HepG2EWSR1
HSPE1ENSG00000115541.62511.830203337.30750-0.409904.129001.67210HepG2EXOSC5
HSPE1ENSG00000115541.62473.116203302.22660-0.417106.026504.26020HepG2FAM120A
HSPE1ENSG00000115541.64402.461506306.96330-0.518604.849503.85470HepG2FIP1L1
HSPE1ENSG00000115541.62234.543804168.84050-0.8997021.0661019.01010HepG2FUBP3
HSPE1ENSG00000115541.64783.464106460.29680-0.433504.429103.28980HepG2G3BP2
HSPE1ENSG00000115541.61907.478303289.52770-0.7862012.1770010.38490HepG2GEMIN5
HSPE1ENSG00000115541.63822.941005530.46340-0.532705.825104.33180HepG2GNB2L1
HSPE1ENSG00000115541.64561.924907384.28640-0.694809.253908.12710HepG2GPKOW
HSPE1ENSG00000115541.63718.691705280.24720-0.5058013.8289011.90970HepG2HDGF
HSPE1ENSG00000115541.61771.850304828.27330-1.4463050.2538048.21870HepG2HNRNPA1
HSPE1ENSG00000115541.67375.762508945.63020-0.278404.960003.76790HepG2HNRNPA2B1
HSPE1ENSG00000115541.64640.711407289.23060-0.651409.796108.55170HepG2HNRNPF
HSPE1ENSG00000115541.65092.746006161.08710-0.274702.285601.64720HepG2HNRNPK
HSPE1ENSG00000115541.65713.997608866.47490-0.6339032.8510030.84450HepG2HNRNPL
HSPE1ENSG00000115541.64687.402607046.99370-0.588204.101803.35090HepG2HNRNPLL
HSPE1ENSG00000115541.63510.336004351.91110-0.310003.231502.21130HepG2HNRNPM
HSPE1ENSG00000115541.64451.761805335.16660-0.261204.475203.72050HepG2HNRNPU
HSPE1ENSG00000115541.64177.538007177.86430-0.7809016.5356014.92900HepG2IGF2BP1
HSPE1ENSG00000115541.64348.737105449.67530-0.325607.005205.89380HepG2ILF2
HSPE1ENSG00000115541.63318.107605055.76060-0.6076026.6911024.00260HepG2KIF1C
HSPE1ENSG00000115541.63472.290505435.65900-0.646608.225505.52940HepG2LSM11
HSPE1ENSG00000115541.65079.956206562.37110-0.369402.847402.18340HepG2MAGOH
HSPE1ENSG00000115541.64068.253405105.04260-0.327503.457602.55360HepG2MSI2
HSPE1ENSG00000115541.64448.964507187.81960-0.692106.287504.79510HepG2MTPAP
HSPE1ENSG00000115541.63335.660604286.58020-0.361903.860502.42400HepG2NAA15
HSPE1ENSG00000115541.64969.968306754.96440-0.442704.083003.31800HepG2NCBP2
HSPE1ENSG00000115541.64242.945403062.777400.470103.124301.60410HepG2NKRF
HSPE1ENSG00000115541.67375.305009651.84830-0.388106.667205.48970HepG2NOL12
HSPE1ENSG00000115541.62512.241806016.58810-1.2600018.7859016.95540HepG2PABPC4
HSPE1ENSG00000115541.63805.873405259.64130-0.466705.016002.69470HepG2PES1
HSPE1ENSG00000115541.62292.087603055.35020-0.414706.096904.31060HepG2PKM
HSPE1ENSG00000115541.62383.750904758.52110-0.9973038.6151036.12560HepG2PPIL4
HSPE1ENSG00000115541.65045.944704198.185100.265304.359503.41290HepG2PRPF4
HSPE1ENSG00000115541.64538.371206361.36680-0.4872012.2804011.29050HepG2PTBP1
HSPE1ENSG00000115541.67126.689709773.56770-0.455708.454007.30950HepG2PUM2
HSPE1ENSG00000115541.63875.209605633.43960-0.5397018.9681017.61540HepG2PUS1
HSPE1ENSG00000115541.63889.796406888.87180-0.8246026.5620024.91680HepG2QKI
HSPE1ENSG00000115541.62384.098203320.59210-0.478004.036301.91860HepG2RBM14
HSPE1ENSG00000115541.64708.271606252.33780-0.409204.320803.49310HepG2RBM25
HSPE1ENSG00000115541.65725.516607079.33880-0.306205.829505.09050HepG2NELFE
HSPE1ENSG00000115541.63976.479506593.89850-0.7296022.3697020.90910HepG2RECQL
HSPE1ENSG00000115541.65117.697007851.49360-0.6175010.015508.85330HepG2RPLP0
HSPE1ENSG00000115541.63500.239005445.89400-0.637704.797203.56910HepG2RPS10
HSPE1ENSG00000115541.62865.874003595.10200-0.327103.576702.88710HepG2RPS19
HSPE1ENSG00000115541.65138.179606622.46080-0.366108.191607.25730HepG2SF3B4
HSPE1ENSG00000115541.66140.557908834.65300-0.5248020.1430018.59060HepG2SLBP
HSPE1ENSG00000115541.63257.582005409.14050-0.731603.262401.52090HepG2SLTM
HSPE1ENSG00000115541.64058.309105654.16740-0.478403.390002.31710HepG2SMNDC1
HSPE1ENSG00000115541.63547.464305396.47490-0.605205.330903.05910HepG2SND1
HSPE1ENSG00000115541.66015.984907760.89740-0.367402.060001.39010HepG2SNRNP70
HSPE1ENSG00000115541.68226.039509610.24160-0.224404.283403.69990HepG2SRFBP1
HSPE1ENSG00000115541.610314.535406912.637000.5773011.4129010.59440HepG2SRSF1
HSPE1ENSG00000115541.68102.546609097.24330-0.167102.189201.62490HepG2SRSF5
HSPE1ENSG00000115541.64472.277407161.24500-0.6792025.1281023.43990HepG2SRSF7
HSPE1ENSG00000115541.64277.831705623.98930-0.394707.304706.48460HepG2SRSF9
HSPE1ENSG00000115541.66717.808308343.89590-0.312707.188806.43740HepG2SSB
HSPE1ENSG00000115541.64270.585003220.370300.407103.189001.81970HepG2SSRP1
HSPE1ENSG00000115541.63779.158205180.41020-0.455002.626901.45870HepG2SUB1
HSPE1ENSG00000115541.69274.0303010345.96110-0.157802.576201.97160HepG2SUCLG1
HSPE1ENSG00000115541.64516.516903260.192100.470203.432001.94400HepG2SUGP2
HSPE1ENSG00000115541.64925.755106775.81850-0.460102.378501.74510HepG2SUPV3L1
HSPE1ENSG00000115541.64384.155906213.96280-0.5032011.4257010.40900HepG2TAF15
HSPE1ENSG00000115541.63437.361906869.60980-0.9989023.8337022.10610HepG2TARDBP
HSPE1ENSG00000115541.63083.205805709.13260-0.8888024.0964021.68600HepG2TIA1
HSPE1ENSG00000115541.64052.313505183.65370-0.355205.173404.53350HepG2TIAL1
HSPE1ENSG00000115541.63862.984105566.63920-0.527103.693402.00690HepG2TRA2A
HSPE1ENSG00000115541.66869.866109001.49900-0.389903.899402.84020HepG2TUFM
HSPE1ENSG00000115541.64434.097405395.53830-0.283102.314901.73510HepG2U2AF1
HSPE1ENSG00000115541.64221.674909528.06090-1.1744025.1547022.71070HepG2UBE2L3
HSPE1ENSG00000115541.64600.661805538.30530-0.267604.714703.84320HepG2UPF1
HSPE1ENSG00000115541.67638.700505347.046700.514507.649106.73390HepG2UTP3
HSPE1ENSG00000115541.63731.826304142.99640-0.150802.015301.42810HepG2ZC3H8
HSPE1ENSG00000115541.65174.161706091.10380-0.235403.950003.32790HepG2ZNF622
HSPE1ENSG00000115541.64009.527005538.89440-0.466203.304401.87610HepG2ZRANB2
HSPE1ENSG00000115541.62910.319601837.682900.6632019.2278017.84990K562AGGF1
HSPE1ENSG00000115541.63247.941401912.183400.7642013.9346012.29400K562AKAP8L
HSPE1ENSG00000115541.62512.273406337.94260-1.3350012.6539011.53100K562AQR
HSPE1ENSG00000115541.62771.555202006.323800.466008.066906.38540K562ATP5C1
HSPE1ENSG00000115541.63649.903504574.87940-0.325905.106603.22270K562BCCIP
HSPE1ENSG00000115541.62971.196104421.03110-0.5733018.3782015.93020K562BCLAF1
HSPE1ENSG00000115541.62234.611703746.61080-0.745602.657501.80320K562BOP1
HSPE1ENSG00000115541.62488.014404555.52790-0.8726010.904408.18010K562BUD13
HSPE1ENSG00000115541.61265.105501691.87790-0.419403.590202.35470K562CCAR1
HSPE1ENSG00000115541.62343.089703244.74240-0.469705.553703.76030K562CIRBP
HSPE1ENSG00000115541.61967.849403984.10220-1.017603.982403.04220K562CPSF6
HSPE1ENSG00000115541.62172.080903354.01100-0.6268013.9785011.40060K562CSTF2
HSPE1ENSG00000115541.62936.014803776.25870-0.363106.604104.69310K562DDX21
HSPE1ENSG00000115541.63711.282805917.75160-0.6731023.6742021.95100K562DDX47
HSPE1ENSG00000115541.61451.390101893.90780-0.383903.216601.77200K562DHX30
HSPE1ENSG00000115541.63203.436302057.702500.6385015.7657013.31760K562DKC1
HSPE1ENSG00000115541.61553.986401995.91850-0.361104.979103.33040K562EIF2S1
HSPE1ENSG00000115541.63398.327505702.48500-0.7468024.9848023.18310K562EIF2S2
HSPE1ENSG00000115541.6750.522801720.99190-1.197306.043004.52300K562EIF3A
HSPE1ENSG00000115541.61902.632502686.14550-0.497507.069205.00570K562EXOSC5
HSPE1ENSG00000115541.62307.390304052.99390-0.812703.014602.12030K562FMR1
HSPE1ENSG00000115541.62229.992203434.95860-0.623302.170401.36550K562FTO
HSPE1ENSG00000115541.64070.172901974.395101.0436013.5046012.27070K562FXR1
HSPE1ENSG00000115541.62934.219904082.70100-0.476509.239907.25380K562GLRX3
HSPE1ENSG00000115541.61882.263903804.14100-1.015103.831802.90440K562GPKOW
HSPE1ENSG00000115541.62550.584404013.67800-0.6541012.8794010.83540K562HNRNPA1
HSPE1ENSG00000115541.61401.311702935.05400-1.066605.247404.44970K562HNRNPC
HSPE1ENSG00000115541.65322.718503866.903700.460904.351903.16790K562HNRNPM
HSPE1ENSG00000115541.63549.840304444.74370-0.324304.732103.55670K562HNRNPU
HSPE1ENSG00000115541.62005.364703027.28780-0.594205.839004.11280K562IGF2BP2
HSPE1ENSG00000115541.62266.961203079.24140-0.441805.042003.34200K562IGF2BP3
HSPE1ENSG00000115541.62862.590102029.335900.496206.192404.84730K562KIF1C
HSPE1ENSG00000115541.61784.409303247.46530-0.863903.257102.23560K562KRR1
HSPE1ENSG00000115541.63353.370002273.364400.560709.347107.47980K562MBNL1
HSPE1ENSG00000115541.62393.983103713.13780-0.633202.150401.37810K562METAP2
HSPE1ENSG00000115541.63251.036904292.41790-0.400909.657108.24240K562MTPAP
HSPE1ENSG00000115541.62566.914001593.461100.687802.291801.50690K562NAA15
HSPE1ENSG00000115541.61494.991401895.93410-0.342802.955801.68600K562NCBP2
HSPE1ENSG00000115541.63024.279104769.31660-0.6572036.9291034.73600K562NSUN2
HSPE1ENSG00000115541.62297.199703416.76430-0.572806.353805.09130K562PCBP3
HSPE1ENSG00000115541.61890.177202620.75520-0.471506.571005.34690K562POLR2G
HSPE1ENSG00000115541.66382.695005336.930100.258102.011701.31610K562PPIG
HSPE1ENSG00000115541.613863.052709731.000500.5105011.002808.80500K562PUM1
HSPE1ENSG00000115541.63066.336401896.425400.693107.967207.09290K562PUS1
HSPE1ENSG00000115541.6931.915901804.51300-0.953307.810104.50270K562RBFOX2
HSPE1ENSG00000115541.62736.898201847.727700.5667011.010109.84960K562RBM15
HSPE1ENSG00000115541.65776.800107206.12730-0.319003.505901.68670K562RBM17
HSPE1ENSG00000115541.62183.363002964.25890-0.441104.895503.73860K562RBM22
HSPE1ENSG00000115541.61614.262202399.54430-0.571902.271101.37720K562RCC2
HSPE1ENSG00000115541.63342.959904706.01670-0.4934011.5883010.01510K562SF3A3
HSPE1ENSG00000115541.62135.793503616.76620-0.759902.694601.73240K562SF3B1
HSPE1ENSG00000115541.62159.165602693.15210-0.318802.235701.46890K562SF3B4
HSPE1ENSG00000115541.63574.054304821.40840-0.4319013.3884011.53710K562SRPK2
HSPE1ENSG00000115541.61840.595202861.97250-0.636807.661905.81140K562SRSF5
HSPE1ENSG00000115541.62375.680703370.12410-0.5045011.180008.80230K562SRSF7
HSPE1ENSG00000115541.62125.126302784.58140-0.389903.317801.89510K562SSB
HSPE1ENSG00000115541.68080.252106168.394400.389404.210502.50210K562SSRP1
HSPE1ENSG00000115541.61567.609303060.71120-0.965304.691503.34010K562SUPV3L1
HSPE1ENSG00000115541.63968.817702628.712800.5943011.599709.92650K562SYNCRIP
HSPE1ENSG00000115541.61871.274503067.05610-0.7128010.534909.00650K562TARDBP
HSPE1ENSG00000115541.61957.537102958.50940-0.5958010.150608.46990K562TIA1
HSPE1ENSG00000115541.62346.767302903.06470-0.306902.644201.57940K562TRA2A
HSPE1ENSG00000115541.64391.609205499.50510-0.324602.879901.46010K562TRIP6
HSPE1ENSG00000115541.64560.844805567.62190-0.287804.222302.65370K562TROVE2
HSPE1ENSG00000115541.61944.376903238.73370-0.736103.292802.17750K562UCHL5
HSPE1ENSG00000115541.62705.871805057.00310-0.9022044.2422041.81680K562UPF1
HSPE1ENSG00000115541.62443.217504327.12500-0.8246019.3996017.12330K562WDR3
HSPE1ENSG00000115541.64611.729407140.85110-0.630804.817403.63170K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HSPE1 is not available on ENCORE database.





4 RBPs can affect the splicing of HSPE1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIHSPE1ENSG00000115541.6chr2+1983677621983681051983677621983678521983679321983681050.075000.000000.00000includedK562PUS1
RIHSPE1ENSG00000115541.6chr2+1983677621983681051983677621983678521983679321983681050.077000.000000.00000includedHepG2U2AF2
RIHSPE1ENSG00000115541.6chr2+1983677621983681051983677621983678521983679321983681050.059000.000000.00000includedHepG2U2AF1
RIHSPE1ENSG00000115541.6chr2+1983677621983681051983677621983678521983679321983681050.054000.000000.00000includedK562U2AF2
RIHSPE1ENSG00000115541.6chr2+1983677621983681051983677621983678521983679321983681050.067000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HSPE1 is not avaliable on ENCORE database.