SPIDR

General Information

Gene Name       : SPIDR
Gene ID             : ENSG00000164808.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SPIDR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPIDRENSG00000164808.1619.6023.3121.45ENCSR000AEF
HepG2SPIDRENSG00000164808.1625.1929.3827.29ENCSR985KAT
K562SPIDRENSG00000164808.1632.8926.9829.94ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPIDR is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPIDR RNA is bound by 27 proteins.  







eCLIP assay for SPIDR is not avaliable on ENCORE database.





27 proteins are bound to SPIDR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr84832046448320520+3'-UTR,5'-UTR,CDS,intron-Distal3.810057.23562HepG2BCLAF1
chr84864786748647896+3'-UTR,CDS,intron-Proximal3.354963.32039HepG2PPIG
chr84835290748353067+3'-UTR,5'-UTR,CDS3.976065.42720K562UCHL5
chr84835288248353030+3'-UTR,5'-UTR,CDS,intron-Proximal4.3639116.23926HepG2BCLAF1
chr84861297048613036+3'-UTR,CDS3.673686.54857HepG2PPIG
chr84861297548613034+3'-UTR,CDS3.872793.31827HepG2GRWD1
chr84858641548586501+3'-UTR,CDS3.871479.24553HepG2PPIG
chr84832042248320464+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.261623.55800HepG2BCLAF1
chr84862600148626104+3'-UTR,CDS,intron-Proximal5.1288418.95782HepG2SF3A3
chr84835292548353006+3'-UTR,5'-UTR,CDS3.636053.34920HepG2HLTF
chr84851159948511674+3'-UTR,CDS,intron-Distal3.155416.00788HepG2PPIG
chr84863976248639824+3'-UTR,5'-UTR,CDS4.043454.96634HepG2PPIG
chr84864806248648136+3'-UTR,CDS4.086925.79513HepG2SUB1
chr84830894248309128+3'-UTR,5'-UTR,CDS,intron-Distal3.397988.71976K562ZNF622
chr84862523148625330+3'-UTR,CDS4.211328.40792HepG2PPIG
chr84835288348352917+3'-UTR,5'-UTR,CDS,intron-Proximal4.333623.87582K562ZNF622
chr84861297348613039+3'-UTR,CDS4.080345.79432HepG2BCLAF1
chr84835303748353130+3'-UTR,5'-UTR,CDS,intron-Proximal3.083535.54854HepG2GRWD1
chr84862522448625285+3'-UTR,CDS4.103293.82000HepG2GRWD1
chr84862606748626203+3'-UTR,CDS5.1449411.08513HepG2PPIG
chr84835297048353008+3'-UTR,5'-UTR,CDS4.357464.38106HepG2PPIG
chr84850839948508523+3'-UTR,CDS5.6301110.12910HepG2BCLAF1
chr84862618048626239+3'-UTR,CDS,intron-Proximal5.525965.35117HepG2PRPF8
chr84864153848641602+3'-UTR,CDS,intron-Distal4.416164.96634HepG2PPIG
chr84830895048309035+3'-UTR,5'-UTR,CDS,intron-Distal4.428578.41475HepG2BCLAF1
chr84820362148203661+5'-UTR,CDS,intron-Proximal3.787867.23562HepG2BCLAF1
chr84820657348206622+5'-UTR,CDS,intron-Distal,intron-Proximal3.495617.36645HepG2PPIG
chr84819662148196685+5'-UTR,CDS,intron-Distal,intron-Proximal3.515936.54857HepG2PPIG
chr84820651448206573+5'-UTR,CDS,intron-Distal3.546079.75394HepG2PPIG
chr84820368048203720+5'-UTR,CDS3.692755.24452HepG2PPIG
chr84820645548206505+5'-UTR,CDS,intron-Distal,intron-Proximal5.283828.41647HepG2BCLAF1
chr84820646148206622+5'-UTR,CDS,intron-Distal,intron-Proximal4.420309.94686HepG2GRWD1
chr84819661648196683+5'-UTR,CDS,intron-Distal,intron-Proximal4.220583.71613K562UCHL5
chr84820366148203727+5'-UTR,CDS,intron-Proximal3.8147210.05563HepG2BCLAF1
chr84819661548196651+5'-UTR,CDS,intron-Distal,intron-Proximal3.097813.17744HepG2GRWD1
chr84820650548206577+5'-UTR,CDS,intron-Distal5.0706113.80283HepG2BCLAF1
chr84820365348203723+5'-UTR,CDS4.218374.69889HepG2GRWD1
chr84820362048203653+5'-UTR,CDS,intron-Proximal3.915513.34184HepG2GRWD1
chr84819661648196639+5'-UTR,CDS,intron-Distal,intron-Proximal3.372823.28366HepG2BCLAF1
chr84819665148196684+5'-UTR,CDS,intron-Distal,intron-Proximal3.424565.10069HepG2GRWD1
chr84819663948196684+5'-UTR,CDS,intron-Distal,intron-Proximal4.026888.51432HepG2BCLAF1
chr84819249048192568+5'-UTR,CDS,intron-Distal4.147446.36347HepG2PPIG
chr84837223548372315+intron-Distal5.203188.03988K562EXOSC5
chr84842235648422396+intron-Distal3.198003.89889HepG2HNRNPL
chr84820917148209305+intron-Distal3.843855.89423HepG2HNRNPM
chr84840554548405667+intron-Distal3.998474.89657K562EIF4G2
chr84830636148306493+intron-Distal5.313029.74894HepG2PTBP1
chr84817368648173765+intron-Distal4.047503.29248HepG2SUGP2
chr84844110248441197+intron-Distal4.072674.15306K562SAFB2
chr84817366048173771+intron-Distal,intron-Proximal4.937097.45950HepG2PRPF4
chr84864764348647765+intron-Distal4.717004.67055K562EIF4G2
chr84825916748259208+intron-Distal4.343557.31365K562EXOSC5
chr84821387348213920+intron-Distal4.118213.59909K562EXOSC5
chr84825883348258877+intron-Distal5.007027.06134K562EXOSC5
chr84836432948364469+intron-Distal3.955757.40393K562SAFB2
chr84849437948494476+intron-Distal4.592615.20135HepG2QKI
chr84820904048209133+intron-Distal4.903797.06134K562EXOSC5
chr84837629348376392+intron-Distal3.983903.10466K562SAFB2
chr84836585448365958+intron-Distal3.883363.50894K562SAFB2
chr84820932148209409+intron-Distal4.093613.60235HepG2HNRNPM
chr84842244948422504+intron-Distal3.784795.99369K562HNRNPL
chr84836480348364886+intron-Distal4.107093.50894K562SAFB2
chr84837137548371473+intron-Distal5.6993512.32537K562EXOSC5
chr84842233248422401+intron-Distal4.478454.94713K562HNRNPL
chr84836277248362845+intron-Distal4.072674.15306K562SAFB2
chr84842242348422501+intron-Distal4.076118.36635HepG2HNRNPL
chr84820920048209276+intron-Distal4.743985.76606K562EXOSC5
chr84825890848258957+intron-Distal4.729413.59909K562EXOSC5
chr84837519948375293+intron-Distal3.711383.19638K562SAFB2
chr84842250548422585+intron-Distal3.347045.61046K562AGGF1
chr84836549948365559+intron-Distal3.838263.50894K562SAFB2
chr84836438948364464+intron-Distal4.725085.29868K562UCHL5
chr84834723248347314+intron-Distal4.772563.78039K562QKI
chr84837222648372309+intron-Distal4.978285.70028HepG2MATR3
chr84862550848625571+intron-Distal,intron-Proximal4.165564.22893K562RBM15
chr84820932448209422+intron-Distal3.600095.32485HepG2SUGP2
chr84826155448261612+intron-Distal4.064403.27946HepG2HNRNPM
chr84842250448422567+intron-Distal5.069948.16758K562HNRNPL
chr84823573548235852+intron-Distal3.860353.26999K562KHSRP
chr84842251048422559+intron-Distal5.222778.21618HepG2HNRNPL
chr84842068348420789+intron-Distal4.294804.51735HepG2QKI
chr84825956448259644+intron-Distal4.229533.51329HepG2MATR3
chr84836879048368876+intron-Distal3.761503.12651K562SAFB2
chr84842245248422580+intron-Distal4.107474.99558HepG2GTF2F1
chr84842245548422505+intron-Distal3.607655.99826K562AGGF1
chr84837231548372354+intron-Distal4.522874.48560K562EXOSC5
chr84862558148625640+intron-Distal4.103293.82000HepG2GRWD1
chr84836170348361808+intron-Distal4.157514.16015K562SAFB2
chr84837723048377312+intron-Distal5.1644916.88044HepG2PCBP2
chr84825189048251991+intron-Distal3.421293.06005HepG2QKI
chr84826126248261326+intron-Distal4.381964.87593HepG2MATR3
chr84817366848173742+intron-Distal,intron-Proximal4.164673.70291HepG2FAM120A
chr84823658048236670+intron-Distal3.696293.25538K562KHSRP
chr84820904248209133+intron-Distal3.016543.10883HepG2SUGP2
chr84838286348382918+intron-Distal4.256064.15306K562SAFB2
chr84826103648261110+intron-Distal4.258273.89080K562EXOSC5
chr84843204348432099+intron-Distal4.337085.27745HepG2ILF3
chr84830640248306477+intron-Distal4.348134.22415K562PTBP1
chr84824675948246873+intron-Distal4.5315812.89363K562KHSRP
chr84837693048377008+intron-Distal4.270634.15306K562SAFB2
chr84821387148213924+intron-Distal4.273263.78432HepG2MATR3
chr84823689548237002+intron-Distal4.593125.36996HepG2PCBP2
chr84820930348209430+intron-Distal5.013006.41304K562EXOSC5
chr84840358648403693+intron-Distal4.3972410.99072HepG2CSTF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPIDR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPIDR is not available on ENCORE database.

  • 59 RBPs can affect the levels of SPIDR.  








The Knockdown/knockout RNA-Seq assay for SPIDR is not available on ENCORE database.





59 RBPs can affect the gene expression of SPIDR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPIDRENSG00000164808.12544.77830742.04100-0.445805.013604.24200HepG2ACO1
SPIDRENSG00000164808.121029.92600850.566600.275902.458001.80420HepG2AUH
SPIDRENSG00000164808.12511.17650741.79010-0.537207.112606.13750HepG2CKAP4
SPIDRENSG00000164808.12505.37330766.50730-0.601003.160502.33970HepG2CNOT7
SPIDRENSG00000164808.12540.02620912.77330-0.7572012.3936011.22270HepG2CELF1
SPIDRENSG00000164808.12573.30850855.28580-0.577104.409303.63350HepG2DDX3X
SPIDRENSG00000164808.12519.30920700.05350-0.430902.558201.66930HepG2EEF2
SPIDRENSG00000164808.12408.48990568.31010-0.476402.489401.62740HepG2EIF3D
SPIDRENSG00000164808.12825.43810529.135600.641405.768904.64760HepG2FUBP3
SPIDRENSG00000164808.12527.80560739.70860-0.487003.475602.69750HepG2HNRNPK
SPIDRENSG00000164808.12706.41990894.09660-0.339903.692502.92180HepG2HNRNPL
SPIDRENSG00000164808.12475.82520624.10150-0.391302.199401.63170HepG2HNRNPLL
SPIDRENSG00000164808.12513.76940709.35430-0.465405.173304.36440HepG2HNRNPU
SPIDRENSG00000164808.12571.60290742.58980-0.377602.212701.60050HepG2IGF2BP2
SPIDRENSG00000164808.12522.64820747.23110-0.515702.710801.40960HepG2ILF3
SPIDRENSG00000164808.12439.22330730.21250-0.733405.722803.91910HepG2KHDRBS1
SPIDRENSG00000164808.12494.88500686.03910-0.471203.594502.29900HepG2LARP7
SPIDRENSG00000164808.12492.70790720.26520-0.547804.557502.98950HepG2LIN28B
SPIDRENSG00000164808.12464.45390792.19870-0.770306.492005.55890HepG2MATR3
SPIDRENSG00000164808.12608.90790810.86320-0.413202.466101.86680HepG2NCBP2
SPIDRENSG00000164808.12385.83020700.53750-0.860505.257204.00510HepG2PABPC1
SPIDRENSG00000164808.12517.56910766.65010-0.566803.199902.08520HepG2PCBP2
SPIDRENSG00000164808.12606.80980929.04680-0.614506.674205.80160HepG2PUF60
SPIDRENSG00000164808.12697.57220986.20650-0.499508.132107.22620HepG2PUM1
SPIDRENSG00000164808.12564.69570816.22520-0.531505.734505.05680HepG2RBM22
SPIDRENSG00000164808.12601.93160827.26040-0.458703.466302.34970HepG2RBM27
SPIDRENSG00000164808.12431.54770671.77280-0.638504.665603.28390HepG2RCC2
SPIDRENSG00000164808.12528.64800726.76420-0.459202.154101.31890HepG2RPS10
SPIDRENSG00000164808.12542.67460762.93830-0.491503.707202.78540HepG2RPS2
SPIDRENSG00000164808.12521.80660778.81060-0.577804.956303.50130HepG2RPS5
SPIDRENSG00000164808.12696.64310994.04170-0.512903.320502.57980HepG2SF3A3
SPIDRENSG00000164808.12617.78260747.00660-0.274002.083001.55900HepG2SF3B4
SPIDRENSG00000164808.12573.70100736.67590-0.360703.673302.95010HepG2SMN1
SPIDRENSG00000164808.12578.75910917.27720-0.6644010.334609.22710HepG2SRSF5
SPIDRENSG00000164808.12521.60510698.75750-0.421803.927703.12000HepG2SRSF7
SPIDRENSG00000164808.12467.33970634.30530-0.440704.397303.73160HepG2SRSF9
SPIDRENSG00000164808.12873.393901043.21500-0.256302.554301.95240HepG2SUCLG1
SPIDRENSG00000164808.12858.78180700.764600.293302.241501.72810HepG2TAF15
SPIDRENSG00000164808.12561.49580689.25620-0.295801.898901.46700HepG2TIAL1
SPIDRENSG00000164808.12436.95550706.06150-0.692306.124005.20590HepG2U2AF1
SPIDRENSG00000164808.12393.26410872.17440-1.149103.739502.58320HepG2U2AF2
SPIDRENSG00000164808.12717.62640960.67240-0.420802.500501.70710HepG2UBE2L3
SPIDRENSG00000164808.12628.05160881.56110-0.489206.425705.43430HepG2UPF1
SPIDRENSG00000164808.12771.29720969.55110-0.330003.896703.27730HepG2ZNF622
SPIDRENSG00000164808.12798.986001106.60610-0.469906.112805.32090K562AGGF1
SPIDRENSG00000164808.12917.589301151.47130-0.327602.379201.77300K562AKAP8L
SPIDRENSG00000164808.12625.841301149.60050-0.8773010.544209.50910K562AQR
SPIDRENSG00000164808.12603.18760793.47770-0.395603.460701.95350K562BCCIP
SPIDRENSG00000164808.12865.659701278.70710-0.562802.875801.78720K562CNOT7
SPIDRENSG00000164808.12558.72630786.07500-0.492504.302603.32450K562CPSF6
SPIDRENSG00000164808.121341.499501864.25070-0.474705.994304.56560K562CELF1
SPIDRENSG00000164808.12343.97870573.96590-0.738606.348504.91920K562EFTUD2
SPIDRENSG00000164808.12521.53830750.49890-0.525104.356103.36590K562GPKOW
SPIDRENSG00000164808.12503.33470747.47660-0.570504.458702.86070K562HNRNPK
SPIDRENSG00000164808.12610.00180862.32310-0.499405.368204.11010K562HNRNPU
SPIDRENSG00000164808.12630.96560784.96690-0.315102.210701.39380K562MATR3
SPIDRENSG00000164808.12574.94790732.57460-0.349502.302301.50520K562METAP2
SPIDRENSG00000164808.12499.22480699.84010-0.487303.739702.60340K562PCBP2
SPIDRENSG00000164808.12655.56510876.19350-0.418502.726601.90090K562PCBP3
SPIDRENSG00000164808.12538.84950672.09120-0.318802.089401.39340K562POLR2G
SPIDRENSG00000164808.12366.38780558.53570-0.608304.294803.36090K562PRPF8
SPIDRENSG00000164808.121289.872201654.42470-0.359103.217202.33890K562PUF60
SPIDRENSG00000164808.12861.045801112.65460-0.369803.561202.90200K562RBM15
SPIDRENSG00000164808.12528.45860732.73050-0.471503.711702.72760K562RBM22
SPIDRENSG00000164808.12524.59620713.78490-0.444302.635301.68580K562SF3B1
SPIDRENSG00000164808.12454.06400599.62920-0.401203.012102.11890K562SF3B4
SPIDRENSG00000164808.12628.820901023.33250-0.702602.919601.56510K562SFPQ
SPIDRENSG00000164808.12608.90050749.20650-0.299201.954001.34700K562SRSF1
SPIDRENSG00000164808.12417.15320577.25890-0.468603.703402.77000K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPIDR is not available on ENCORE database.





20 RBPs can affect the splicing of SPIDR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPIDRENSG00000164808.12chr8+486419734864202748641494486416094864786848647936-0.363000.001080.02222excludedK562SF3B4
SESPIDRENSG00000164808.12chr8+486397614863985548626050486262034864786848648478-0.492000.002160.06589excludedK562PRPF8
SESPIDRENSG00000164808.12chr8+483089354830918648206455482066194835288448353104-0.183000.003260.07640excludedK562AKAP8L
SESPIDRENSG00000164808.12chr8+4861689048617136486145174861457748625223486254340.214000.000160.00597includedHepG2HNRNPK
SESPIDRENSG00000164808.12chr8+486419734864202748641494486416094864786848647936-0.238000.000010.00020excludedHepG2U2AF2
SESPIDRENSG00000164808.12chr8+483075374830758148206455482066194830893548309186-0.196000.000340.05506excludedK562DROSHA
SESPIDRENSG00000164808.12chr8+4861689048617136486145174861457748625223486254340.140000.000310.02699includedHepG2HNRNPL
SESPIDRENSG00000164808.12chr8+4824336848243484482036214820372648308935483091860.457000.000020.01085includedK562SBDS
SESPIDRENSG00000164808.12chr8+486145174861457748614282486144264862522348626003-0.240000.000150.00652excludedHepG2SF3A3
SESPIDRENSG00000164808.12chr8+486419734864202748639761486398554864786848647936-0.263000.000990.03052excludedHepG2SF3A3
SESPIDRENSG00000164808.12chr8+483075374830758148206455482066194830893548309186-0.202000.000160.01845excludedK562HNRNPUL1
SESPIDRENSG00000164808.12chr8+486397614863985548626050486262034864786848648478-0.492000.000000.00040excludedHepG2SF3B4
SESPIDRENSG00000164808.12chr8+483089354830918648206455482066194835288448353104-0.192000.002410.06526excludedK562UTP18
SESPIDRENSG00000164808.12chr8+486145174861457748614282486144264862522348626003-0.375000.001380.05208excludedK562SF3B1
SESPIDRENSG00000164808.12chr8+486397614863985548626050486262034864786848648478-0.553000.000100.00619excludedK562SF3B1
A5SSSPIDRENSG00000164808.12chr8+481924494819260548192449481925684819661648196683-0.141000.000040.00543shorterHepG2SF3A3
MXESPIDRENSG00000164808.12chr8+48206455482066194830893548309186482036214820372648352884483531040.077000.000310.030551includedK562LARP4
MXESPIDRENSG00000164808.12chr8+4830893548309186483204224832052348206455482066194835288448353104-0.420000.000030.001202includedHepG2FTO
MXESPIDRENSG00000164808.12chr8+48206455482066194832042248320523482036214820372648352884483531040.165000.004770.075791includedHepG2SRSF1
MXESPIDRENSG00000164808.12chr8+48300904483010974830753748307581482064554820661948308935483091860.230000.004980.054941includedK562DROSHA
MXESPIDRENSG00000164808.12chr8+48308935483091864832042248320523482036214820372648352884483531040.289000.000930.014901includedK562U2AF2
MXESPIDRENSG00000164808.12chr8+4820645548206619483089354830918648203621482037264835288448353104-0.127000.007970.078802includedK562U2AF2
MXESPIDRENSG00000164808.12chr8+4820645548206619483204224832052348203621482037264835288448353104-0.059000.002640.068732includedHepG2RBFOX2
MXESPIDRENSG00000164808.12chr8+48206455482066194830893548309186482036214820372648352884483531040.093000.000930.066011includedK562AARS
MXESPIDRENSG00000164808.12chr8+48206455482066194830893548309186482036214820372648352884483531040.082000.000720.027001includedK562SBDS
MXESPIDRENSG00000164808.12chr8+4864149448641609486419734864202748639761486398554864786848648347-0.257000.003580.085712includedHepG2HNRNPC
MXESPIDRENSG00000164808.12chr8+48206455482066194832042248320523482036214820372648352884483531040.078000.004690.081031includedK562PPIL4
MXESPIDRENSG00000164808.12chr8+4819244948192605481966164819668348173546481735834820362148203726-0.223000.004770.082032includedK562PPIL4
MXESPIDRENSG00000164808.12chr8+48206455482066194832042248320523482036214820372648352884483531040.153000.001830.054761includedK562DDX55
MXESPIDRENSG00000164808.12chr8+4820645548206619483089354830918648203621482037264835288448353104-0.142000.002130.047222includedHepG2HNRNPK
MXESPIDRENSG00000164808.12chr8+48308935483091864832042248320523482036214820372648352884483531040.416000.000380.028291includedHepG2LARP4
MXESPIDRENSG00000164808.12chr8+4820645548206619483089354830918648203621482037264835288448353104-0.060000.001160.057402includedHepG2LARP4
MXESPIDRENSG00000164808.12chr8+48308935483091864832042248320523482036214820372648352884483531040.255000.004600.060811includedK562SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPIDR is not avaliable on ENCORE database.