PROS1

General Information

Gene Name       : PROS1
Gene ID             : ENSG00000184500.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PROS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PROS1ENSG00000184500.150.000.000.00ENCSR000AEF
HepG2PROS1ENSG00000184500.1531.5266.8249.17ENCSR985KAT
K562PROS1ENSG00000184500.1516.1515.3715.76ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PROS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PROS1 RNA is bound by 12 proteins.  







eCLIP assay for PROS1 is not avaliable on ENCORE database.





12 proteins are bound to PROS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr39362495093624988-3'-UTR,CDS,intron-Distal,intron-Proximal3.004954.94039K562YBX3
chr39359232293592381-3'-UTR,intron-Distal3.729423.27226HepG2IGF2BP3
chr39359301493593074-3'-UTR,intron-Distal4.640054.32097HepG2FUBP3
chr39364610193646231-3'-UTR,5'-UTR,CDS,intron-Distal3.431033.79741HepG2GRWD1
chr39364609293646183-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.256607.16838HepG2BCLAF1
chr39362946093629540-3'-UTR,CDS,intron-Distal,intron-Proximal3.5386311.37584K562YBX3
chr39369267193692743-5'-UTR,intron-Distal,intron-Proximal5.2195568.29797HepG2DDX3X
chr39369268493692733-5'-UTR,intron-Distal,intron-Proximal3.257983.70637K562DDX3X
chr39369259693692684-5'-UTR,intron-Distal3.756358.96385K562DDX3X
chr39369252093692595-5'-UTR,CDS,intron-Distal,intron-Proximal5.2538857.90253HepG2DDX3X
chr39369252193692596-5'-UTR,CDS,intron-Distal,intron-Proximal4.111966.02664K562DDX3X
chr39369244493692496-5'-UTR,intron-Distal,intron-Proximal4.116373.45799HepG2U2AF2
chr39369261793692671-5'-UTR,intron-Distal5.0541947.51244HepG2DDX3X
chr39359589393595986-CDS,intron-Distal3.218817.19068K562YBX3
chr39360367393603740-CDS,intron-Distal3.545145.15500HepG2BCLAF1
chr39360367393603740-CDS,intron-Distal4.042293.56019HepG2GRWD1
chr39359582293595908-CDS,intron-Distal3.033763.39306HepG2GRWD1
chr39359808293598156-CDS,intron-Distal4.623924.89596HepG2LIN28B
chr39361188993611936-CDS,intron-Distal3.101433.51818HepG2LIN28B
chr39360360093603673-CDS,intron-Distal3.448824.34695HepG2BCLAF1
chr39360357993603651-CDS,intron-Distal6.0014813.26884HepG2LIN28B
chr39360357293603651-CDS,intron-Distal4.926957.88172K562LIN28B
chr39366960093669754-intron-Distal5.272287.71312K562EXOSC5
chr39366291193662964-intron-Distal3.761093.72904K562EXOSC5
chr39367173593671810-intron-Distal3.566604.02241K562EXOSC5
chr39366978193669859-intron-Distal3.757984.72029K562MATR3
chr39368892093689011-intron-Distal4.330323.18981K562PTBP1
chr39366613493666185-intron-Distal5.190088.69493K562EXOSC5
chr39366618593666258-intron-Distal4.9518613.19705K562EXOSC5
chr39366971093669823-intron-Distal4.924687.51321HepG2MATR3
chr39367230593672343-intron-Distal4.111313.30696K562EXOSC5
chr39364712993647168-intron-Distal3.475933.64859K562AGGF1
chr39366962193669710-intron-Distal4.319194.31720HepG2MATR3
chr39366393093664033-intron-Distal4.257983.98115K562MATR3
chr39366396793664025-intron-Distal4.799505.12361K562EXOSC5
chr39366298993663118-intron-Distal3.675427.56703K562EXOSC5
chr39366970893669781-intron-Distal4.412044.24113K562MATR3
chr39367040793670481-intron-Distal3.457253.72904K562EXOSC5
chr39369181793691878-intron-Distal3.470283.32861HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PROS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PROS1 is not available on ENCORE database.

  • 113 RBPs can affect the levels of PROS1.  








The Knockdown/knockout RNA-Seq assay for PROS1 is not available on ENCORE database.





113 RBPs can affect the gene expression of PROS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PROS1ENSG00000184500.103735.798702650.592800.495005.776904.28040HepG2AATF
PROS1ENSG00000184500.102243.184302905.16210-0.373105.598604.79320HepG2ACO1
PROS1ENSG00000184500.106562.611704771.678400.459703.995003.37310HepG2AKAP1
PROS1ENSG00000184500.106321.629803948.244000.679009.581108.17820HepG2ASCC1
PROS1ENSG00000184500.104666.240504142.190800.171802.095601.48270HepG2AUH
PROS1ENSG00000184500.101944.959503166.37420-0.703104.934603.67960HepG2BCCIP
PROS1ENSG00000184500.101476.127502751.67750-0.898507.113905.75200HepG2BCLAF1
PROS1ENSG00000184500.102070.264302795.28760-0.433204.793804.03340HepG2BOP1
PROS1ENSG00000184500.103433.598802598.506500.401904.087102.60350HepG2BUD13
PROS1ENSG00000184500.104950.771703823.516700.372703.062602.25390HepG2CALR
PROS1ENSG00000184500.106039.627703751.077500.6871010.278808.87190HepG2CIRBP
PROS1ENSG00000184500.102379.369102904.62250-0.287805.406904.53460HepG2CKAP4
PROS1ENSG00000184500.105132.774402566.181801.0000021.9966020.29430HepG2CPSF6
PROS1ENSG00000184500.101159.973701956.34220-0.754105.904104.42400HepG2CSTF2
PROS1ENSG00000184500.106415.575304658.630000.4616010.427309.33430HepG2CELF1
PROS1ENSG00000184500.102230.188602686.90090-0.268804.473703.44500HepG2DDX19B
PROS1ENSG00000184500.103672.012502861.990700.359504.271303.12630HepG2DDX24
PROS1ENSG00000184500.103323.903804571.08030-0.459704.405103.62980HepG2DDX3X
PROS1ENSG00000184500.103954.541203029.616800.384303.299802.23280HepG2DHX30
PROS1ENSG00000184500.102215.147303113.35570-0.4911014.7735013.38950HepG2DNAJC2
PROS1ENSG00000184500.104178.330202693.295500.633504.120002.75520HepG2AGO1
PROS1ENSG00000184500.102456.286604171.79260-0.764209.372008.20320HepG2EIF4A3
PROS1ENSG00000184500.102839.307604061.45160-0.516503.760102.96440HepG2EIF4B
PROS1ENSG00000184500.104323.109604941.92420-0.193002.775501.93730HepG2EIF4G1
PROS1ENSG00000184500.107532.796904734.133100.670006.297605.09120HepG2EIF4G2
PROS1ENSG00000184500.103680.498704755.66500-0.369707.510406.60100HepG2ETF1
PROS1ENSG00000184500.101823.659302838.94390-0.6385010.782009.16630HepG2EWSR1
PROS1ENSG00000184500.104288.918802570.672900.738403.332102.21190HepG2FTO
PROS1ENSG00000184500.105648.762703904.378600.532705.555804.62670HepG2G3BP1
PROS1ENSG00000184500.102065.023402908.84510-0.494304.591103.77800HepG2GPKOW
PROS1ENSG00000184500.104827.074203394.696300.507802.701001.35470HepG2HLTF
PROS1ENSG00000184500.101996.302603171.23330-0.6677011.4828010.30840HepG2HNRNPA1
PROS1ENSG00000184500.106039.784004603.814400.391608.179306.72840HepG2HNRNPA2B1
PROS1ENSG00000184500.102874.197203527.39480-0.295402.675701.99300HepG2HNRNPC
PROS1ENSG00000184500.102286.415602720.90840-0.251003.101502.34480HepG2HNRNPF
PROS1ENSG00000184500.106235.131803952.808900.6574010.701409.40940HepG2HNRNPK
PROS1ENSG00000184500.103847.621102775.975500.470904.203603.44260HepG2HNRNPLL
PROS1ENSG00000184500.102684.157303504.07500-0.384607.919706.93410HepG2HNRNPU
PROS1ENSG00000184500.105200.520503444.176700.594403.367502.00470HepG2HSPD1
PROS1ENSG00000184500.101941.346302679.32680-0.464806.541405.47110HepG2IGF2BP1
PROS1ENSG00000184500.105290.004603991.753800.406102.829101.81560HepG2KHSRP
PROS1ENSG00000184500.103194.283202655.739500.266305.033103.66510HepG2KIF1C
PROS1ENSG00000184500.103833.234905857.69320-0.611802.301401.54990HepG2LARP4
PROS1ENSG00000184500.101934.124104210.03760-1.1222021.9141020.16090HepG2MAGOH
PROS1ENSG00000184500.103730.585502853.250000.386703.808101.93230HepG2MARK2
PROS1ENSG00000184500.103312.534704233.69710-0.354002.529701.92380HepG2MATR3
PROS1ENSG00000184500.104094.779302834.656800.530507.778906.48580HepG2MSI2
PROS1ENSG00000184500.104665.425902831.400700.720405.872904.43240HepG2MTPAP
PROS1ENSG00000184500.103054.039902379.991500.359703.161501.86210HepG2NAA15
PROS1ENSG00000184500.102121.814004333.50280-1.0302017.9768016.45670HepG2NCBP2
PROS1ENSG00000184500.102187.820003587.77690-0.713604.768803.58090HepG2PABPC1
PROS1ENSG00000184500.105617.307303859.627100.541305.999304.94660HepG2PABPC4
PROS1ENSG00000184500.102786.383603614.63000-0.375507.555806.63090HepG2PCBP1
PROS1ENSG00000184500.105885.615703354.850700.810807.584905.95040HepG2PCBP2
PROS1ENSG00000184500.103593.999603125.357700.201502.115801.46440HepG2PPIL4
PROS1ENSG00000184500.101744.567502048.13890-0.231402.680801.91750HepG2PRPF4
PROS1ENSG00000184500.103395.010102402.423100.498805.568604.46510HepG2PRPF8
PROS1ENSG00000184500.105789.125205033.512400.201703.534102.88070HepG2PUM1
PROS1ENSG00000184500.104036.402005029.94810-0.317504.364103.53210HepG2PUM2
PROS1ENSG00000184500.102173.631602959.10950-0.4451010.730709.65430HepG2PUS1
PROS1ENSG00000184500.103011.428903983.40990-0.403606.580105.67690HepG2QKI
PROS1ENSG00000184500.102306.529203974.88180-0.7852024.4330023.19840HepG2RBM22
PROS1ENSG00000184500.105339.289203615.183500.562509.829108.61580HepG2RBM25
PROS1ENSG00000184500.102491.773803298.33340-0.404602.682901.64160HepG2RCC2
PROS1ENSG00000184500.103426.560804093.27850-0.256503.881803.26170HepG2NELFE
PROS1ENSG00000184500.101770.277802930.95400-0.7274012.2149010.95960HepG2RPLP0
PROS1ENSG00000184500.104225.955403179.855600.410202.244601.39160HepG2RPS10
PROS1ENSG00000184500.101359.353702507.34640-0.8832016.8603015.52870HepG2RPS19
PROS1ENSG00000184500.102812.116103746.24250-0.413803.715202.79210HepG2RPS2
PROS1ENSG00000184500.103082.799903940.26540-0.354102.070501.37780HepG2RPS3A
PROS1ENSG00000184500.101358.693103120.54310-1.1996067.2971064.85470HepG2SAFB2
PROS1ENSG00000184500.104873.233802975.653900.711605.444904.47970HepG2SF3A3
PROS1ENSG00000184500.102227.612402747.59700-0.302702.542101.86380HepG2SF3B1
PROS1ENSG00000184500.102701.209703829.31070-0.5035013.1010011.96370HepG2SF3B4
PROS1ENSG00000184500.104159.923203057.208700.444202.579301.82580HepG2SNRNP70
PROS1ENSG00000184500.103563.364104489.52860-0.333306.984306.28890HepG2SRFBP1
PROS1ENSG00000184500.105341.626203996.955800.4183010.9350010.12960HepG2SRSF1
PROS1ENSG00000184500.104733.928202956.624000.679007.143905.47810HepG2SRSF3
PROS1ENSG00000184500.105348.308604681.678800.192002.377901.79230HepG2SRSF5
PROS1ENSG00000184500.103815.710803251.723100.230603.393802.79480HepG2SRSF9
PROS1ENSG00000184500.102463.537503426.85700-0.476203.502802.25200HepG2STIP1
PROS1ENSG00000184500.104410.494105324.54420-0.271704.733803.95890HepG2SUCLG1
PROS1ENSG00000184500.106062.300803592.576800.7547024.3253022.89090HepG2TAF15
PROS1ENSG00000184500.105970.376402706.039901.1415030.0601028.14880HepG2TARDBP
PROS1ENSG00000184500.105193.325103301.134200.6536013.8222011.99030HepG2TIA1
PROS1ENSG00000184500.103920.596504903.02310-0.322602.234501.48640HepG2UBE2L3
PROS1ENSG00000184500.101146.589401831.01610-0.675304.701703.70730HepG2UCHL5
PROS1ENSG00000184500.103640.435502638.951900.4640012.2202010.94400HepG2UPF1
PROS1ENSG00000184500.102021.577502838.71090-0.489802.321301.40780HepG2UPF2
PROS1ENSG00000184500.103434.790302712.459600.340505.595804.15150HepG2UTP18
PROS1ENSG00000184500.101970.024303050.86330-0.631004.143003.26360HepG2XRN2
PROS1ENSG00000184500.102672.455902021.297800.402809.038407.94250HepG2ZC3H8
PROS1ENSG00000184500.101889.197401463.823700.367903.484402.74800K562AKAP8L
PROS1ENSG00000184500.101106.369702072.65610-0.9056015.2814014.05480K562AQR
PROS1ENSG00000184500.102184.773401535.914500.508308.934507.16770K562ATP5C1
PROS1ENSG00000184500.10845.638801133.54100-0.422704.162802.97080K562BCLAF1
PROS1ENSG00000184500.101597.837901198.302100.415003.401802.43420K562BOP1
PROS1ENSG00000184500.102164.895901681.159800.364704.371102.85220K562CCDC124
PROS1ENSG00000184500.10669.56960859.95960-0.361002.993501.89110K562CSTF2
PROS1ENSG00000184500.101346.774601049.149900.360202.288401.35850K562EIF3D
PROS1ENSG00000184500.10713.692101173.60720-0.717609.173307.67600K562EIF4A3
PROS1ENSG00000184500.102789.511802417.675300.206302.280801.42400K562EIF4G2
PROS1ENSG00000184500.10809.971301220.50670-0.591509.092208.06930K562FXR1
PROS1ENSG00000184500.101880.504001326.433200.503502.386401.73650K562G3BP2
PROS1ENSG00000184500.101384.121801877.51980-0.439904.842103.84410K562GRSF1
PROS1ENSG00000184500.10505.650301150.77690-1.1864022.8532021.21910K562HNRNPC
PROS1ENSG00000184500.101376.116201854.63960-0.430503.856602.58170K562HNRNPL
PROS1ENSG00000184500.102396.838801553.462400.6255010.160508.30390K562KIF1C
PROS1ENSG00000184500.10856.853701167.21120-0.445903.402901.74040K562LIN28B
PROS1ENSG00000184500.101120.936101700.39290-0.601208.200806.71670K562MAGOH
PROS1ENSG00000184500.101285.306001697.02090-0.400904.320503.14460K562MATR3
PROS1ENSG00000184500.102227.500201740.273100.356003.789202.69580K562MBNL1
PROS1ENSG00000184500.10889.195801187.39310-0.417203.747102.71730K562METAP2
PROS1ENSG00000184500.101130.499701379.74070-0.287403.254902.38040K562MTPAP
PROS1ENSG00000184500.101868.395001219.807200.615003.302602.32270K562NAA15
PROS1ENSG00000184500.101318.269401661.88860-0.334203.248901.78250K562PCBP1
PROS1ENSG00000184500.101483.31820899.127600.722104.033001.79850K562PRPF6
PROS1ENSG00000184500.10746.805901031.80010-0.466403.104502.14050K562PSIP1
PROS1ENSG00000184500.101232.454601652.00010-0.422704.768403.91850K562PTBP1
PROS1ENSG00000184500.103454.122902805.863100.299803.213202.06010K562PUM1
PROS1ENSG00000184500.102139.378101451.669800.559406.511505.71930K562PUS1
PROS1ENSG00000184500.102156.534501414.468100.6084011.7160010.50560K562RBM15
PROS1ENSG00000184500.101078.026901584.34940-0.555506.390405.04330K562RBM22
PROS1ENSG00000184500.101007.115601347.57300-0.420103.831201.78620K562RECQL
PROS1ENSG00000184500.101951.321001512.699200.367205.091804.01060K562SF3A3
PROS1ENSG00000184500.10865.888401379.82510-0.6722010.634308.90320K562SF3B4
PROS1ENSG00000184500.10860.865401850.02510-1.103705.371803.29740K562SFPQ
PROS1ENSG00000184500.10585.76970892.43950-0.607405.884504.22880K562SRFBP1
PROS1ENSG00000184500.101173.609101619.45370-0.464604.678203.76320K562SRSF1
PROS1ENSG00000184500.10741.87500970.83710-0.388103.059801.93950K562SRSF4
PROS1ENSG00000184500.101286.570301581.08020-0.297402.529601.75170K562TIA1
PROS1ENSG00000184500.101969.168401586.957300.311204.058202.51690K562TROVE2
PROS1ENSG00000184500.101335.467901625.48170-0.283503.277802.49980K562UPF1
PROS1ENSG00000184500.10508.36930846.90450-0.736303.641801.75710K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PROS1 is not available on ENCORE database.





9 RBPs can affect the splicing of PROS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPROS1ENSG00000184500.10chr3-936475459364764193646093936462519369251793692706-0.207000.004380.06678excludedK562SF3B4
SEPROS1ENSG00000184500.10chr3-9364754593647641936460939364625193692517936927060.384000.002640.08114includedK562FXR1
SEPROS1ENSG00000184500.10chr3-9364754593647641936460939364625193692517936927060.159000.000110.00890includedHepG2PTBP1
SEPROS1ENSG00000184500.10chr3-936475459364764193646093936462519369251793692706-0.416000.000000.00291excludedK562BUD13
SEPROS1ENSG00000184500.10chr3-936475459364764193646093936462519369251793692706-0.146000.001420.08703excludedHepG2TIAL1
SEPROS1ENSG00000184500.10chr3-9364754593647641936460939364625193692517936927060.178000.000080.00620includedHepG2PCBP1
SEPROS1ENSG00000184500.10chr3-936475459364764193646093936462519369251793692706-0.181000.001460.04534excludedK562UTP18
SEPROS1ENSG00000184500.10chr3-936475459364764193646093936462519369251793692706-0.147000.000560.07599excludedK562ZC3H8
SEPROS1ENSG00000184500.10chr3-936475459364764193646093936462519369251793692706-0.176000.000370.02001excludedHepG2HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PROS1 is not avaliable on ENCORE database.