KLHL18

General Information

Gene Name       : KLHL18
Gene ID             : ENSG00000114648.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHL18)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHL18ENSG00000114648.1112.7519.3716.06ENCSR000AEF
HepG2KLHL18ENSG00000114648.1121.099.6015.34ENCSR985KAT
K562KLHL18ENSG00000114648.1138.2232.7535.48ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHL18 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHL18 RNA is bound by 13 proteins.  







eCLIP assay for KLHL18 is not avaliable on ENCORE database.





13 proteins are bound to KLHL18 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr34738602547386060+3'-UTR4.136673.20319K562UPF1
chr34738730947387345+3'-UTR4.553915.24231K562UPF1
chr34738198147382066+3'-UTR,CDS,intron-Proximal3.197023.57857HepG2SF3B4
chr34738800747388060+3'-UTR4.136673.69433K562UPF1
chr34738719647387246+3'-UTR5.121376.29854K562UPF1
chr34738208347382159+3'-UTR,CDS4.081813.36385K562UCHL5
chr34732447647324502+5'-UTR,CDS3.346053.72952K562EXOSC5
chr34732445347324582+5'-UTR,CDS3.783793.12746HepG2GRWD1
chr34733707547337119+intron-Distal3.470733.59351HepG2MATR3
chr34733702847337072+intron-Distal5.145588.14620HepG2PTBP1
chr34733707247337119+intron-Distal6.1426217.66638HepG2PTBP1
chr34734167547341752+intron-Distal5.132428.19722HepG2PCBP2
chr34734734747347492+intron-Distal4.136143.49011K562KHSRP
chr34734157447341735+intron-Distal5.1611115.60300K562PTBP1
chr34732467847324773+intron-Distal,intron-Proximal3.686413.15816HepG2PRPF4
chr34735229647352363+intron-Distal3.726063.06015K562MATR3
chr34733690547336952+intron-Distal4.215016.11515K562PTBP1
chr34732474547324800+intron-Distal3.347433.20886K562PRPF8
chr34733707247337117+intron-Distal5.5823411.52400K562PTBP1
chr34734158447341731+intron-Distal3.978283.51329HepG2MATR3
chr34733702647337071+intron-Distal4.350193.98115K562MATR3
chr34733707147337120+intron-Distal4.086505.47496K562MATR3
chr34735183347351908+intron-Distal5.019574.90095K562PTBP1
chr34737171047371806+intron-Distal,intron-Proximal5.4137911.72292K562KHSRP
chr34734157947341675+intron-Distal5.718608.72587HepG2PCBP2
chr34733702547337072+intron-Distal5.0268210.68324K562PTBP1
chr34733560147335711+intron-Distal5.163297.62903HepG2QKI
chr34734159747341744+intron-Distal5.376218.94250HepG2PTBP1
chr34734165247341749+intron-Distal3.498643.37821K562ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHL18 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHL18 is not available on ENCORE database.

  • 107 RBPs can affect the levels of KLHL18.  








The Knockdown/knockout RNA-Seq assay for KLHL18 is not available on ENCORE database.





107 RBPs can affect the gene expression of KLHL18 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHL18ENSG00000114648.7709.47580332.563701.0930019.3851018.09370HepG2ACO1
KLHL18ENSG00000114648.7950.26240335.927901.5001017.9317016.70250HepG2AKAP1
KLHL18ENSG00000114648.7743.80800605.535800.296602.325101.68670HepG2AUH
KLHL18ENSG00000114648.7370.48440253.631000.546603.336702.49960HepG2CALR
KLHL18ENSG00000114648.7365.35390264.075200.468202.252601.55090HepG2CIRBP
KLHL18ENSG00000114648.7660.15940332.536000.9892018.0082016.63440HepG2CKAP4
KLHL18ENSG00000114648.7648.21140358.867400.852905.445304.36950HepG2CNOT7
KLHL18ENSG00000114648.7842.95280395.645901.0911022.3911020.92130HepG2CELF1
KLHL18ENSG00000114648.7328.44620425.37830-0.373102.501601.79070HepG2DAZAP1
KLHL18ENSG00000114648.7427.33270307.594300.474204.019303.03690HepG2DDX19B
KLHL18ENSG00000114648.7348.98160237.038100.557903.177802.45410HepG2DDX21
KLHL18ENSG00000114648.7492.20490321.798700.613003.872603.14360HepG2DDX3X
KLHL18ENSG00000114648.7597.29010408.650600.547503.491302.63520HepG2DDX55
KLHL18ENSG00000114648.7426.78890276.419700.626603.572602.87820HepG2DDX6
KLHL18ENSG00000114648.7241.95330318.18490-0.395102.071001.47210HepG2DKC1
KLHL18ENSG00000114648.7299.66450195.440500.616502.939302.01170HepG2EIF3D
KLHL18ENSG00000114648.7448.38960293.680700.610403.512602.79450HepG2EIF4A3
KLHL18ENSG00000114648.7466.72970285.928300.706803.807303.00480HepG2EIF4B
KLHL18ENSG00000114648.7277.80040402.03480-0.533302.992202.14650HepG2EIF4G2
KLHL18ENSG00000114648.7548.10230695.24490-0.343102.581901.99760HepG2ETF1
KLHL18ENSG00000114648.7489.75770325.013700.591504.650003.57240HepG2EWSR1
KLHL18ENSG00000114648.7725.70540400.971500.855807.816206.59390HepG2FIP1L1
KLHL18ENSG00000114648.7216.68860340.16300-0.650603.077101.74000HepG2FKBP4
KLHL18ENSG00000114648.7448.64260296.294000.598403.651402.86450HepG2FXR1
KLHL18ENSG00000114648.7584.62020274.865401.0887011.154809.86280HepG2G3BP1
KLHL18ENSG00000114648.7184.79050441.93630-1.2579011.3446010.11750HepG2GPKOW
KLHL18ENSG00000114648.7410.14980317.530100.369202.420901.49970HepG2HDGF
KLHL18ENSG00000114648.7434.92100264.982900.714803.311001.78210HepG2HLTF
KLHL18ENSG00000114648.7417.34940278.304600.584503.472002.69430HepG2HNRNPK
KLHL18ENSG00000114648.7268.92070421.74670-0.649203.973603.23370HepG2HNRNPLL
KLHL18ENSG00000114648.7411.93790276.746500.573804.213403.06340HepG2HNRNPM
KLHL18ENSG00000114648.7672.38860279.397901.2669015.9530014.49400HepG2IGF2BP2
KLHL18ENSG00000114648.7724.35170262.189701.466004.239303.02480HepG2IGF2BP3
KLHL18ENSG00000114648.7405.24580297.195000.447303.496502.68030HepG2ILF2
KLHL18ENSG00000114648.7656.65290416.808500.655604.362603.31340HepG2LARP4
KLHL18ENSG00000114648.7594.57000296.397401.004209.840308.62280HepG2MAGOH
KLHL18ENSG00000114648.7752.88810298.059101.3367016.1118014.68470HepG2MATR3
KLHL18ENSG00000114648.7386.64570204.559300.918404.560603.22980HepG2METAP2
KLHL18ENSG00000114648.7433.31800324.668500.416402.601901.81740HepG2MSI2
KLHL18ENSG00000114648.7281.85830430.09630-0.609702.619201.67950HepG2MTPAP
KLHL18ENSG00000114648.7557.52430305.082400.869707.207906.20840HepG2NCBP2
KLHL18ENSG00000114648.7132.21140373.94900-1.5000014.2488012.69350HepG2NSUN2
KLHL18ENSG00000114648.7460.39740315.571100.544803.587001.75440HepG2NUP35
KLHL18ENSG00000114648.7569.08000271.706401.066508.719207.45530HepG2PABPC4
KLHL18ENSG00000114648.7537.53590280.241000.9396012.8098011.65620HepG2PCBP1
KLHL18ENSG00000114648.7187.90070367.34660-0.9672010.235208.88350HepG2PRPF4
KLHL18ENSG00000114648.7598.01370285.159801.0683016.5203015.39820HepG2PTBP1
KLHL18ENSG00000114648.7738.04790427.455400.7878014.3488013.21990HepG2PUM1
KLHL18ENSG00000114648.7588.91640427.135500.463303.675502.90730HepG2PUM2
KLHL18ENSG00000114648.7427.89990338.744200.337002.148701.58940HepG2PUS1
KLHL18ENSG00000114648.7495.42390308.826500.681805.969705.10090HepG2QKI
KLHL18ENSG00000114648.7522.23570389.129100.424402.901502.02590HepG2RBM15
KLHL18ENSG00000114648.71419.99880581.094301.2889012.7844011.83360HepG2RBM22
KLHL18ENSG00000114648.7478.74380313.602500.610203.755402.58920HepG2RBM27
KLHL18ENSG00000114648.7543.18370317.352100.775308.377807.52860HepG2NELFE
KLHL18ENSG00000114648.7376.66180295.576400.349601.873001.35190HepG2RECQL
KLHL18ENSG00000114648.7843.94580625.340300.432403.133902.41400HepG2RPLP0
KLHL18ENSG00000114648.7358.54800190.154700.914907.467806.51750HepG2RPS19
KLHL18ENSG00000114648.7485.09870289.214000.746005.347704.25600HepG2RPS2
KLHL18ENSG00000114648.7469.47810295.236200.669104.230802.88780HepG2RPS5
KLHL18ENSG00000114648.7455.43240311.947000.545803.176002.34160HepG2RRP9
KLHL18ENSG00000114648.7758.16730338.767701.1621011.149409.73470HepG2SF3A3
KLHL18ENSG00000114648.7565.85250296.880900.9304012.0096010.91520HepG2SF3B4
KLHL18ENSG00000114648.7300.91600386.11510-0.359702.091601.46660HepG2SLBP
KLHL18ENSG00000114648.7537.17690302.155800.8300011.5282010.35620HepG2SMN1
KLHL18ENSG00000114648.7412.25160257.521600.678703.860802.71380HepG2SMNDC1
KLHL18ENSG00000114648.71357.54850656.321401.0484030.3707029.17370HepG2SRFBP1
KLHL18ENSG00000114648.7534.94510309.882300.787608.747708.01330HepG2SRSF1
KLHL18ENSG00000114648.7572.68460397.584500.526405.243604.42430HepG2SRSF5
KLHL18ENSG00000114648.7383.31430252.108300.604405.151104.44030HepG2SRSF9
KLHL18ENSG00000114648.7347.30910569.83670-0.714308.692207.88360HepG2SSB
KLHL18ENSG00000114648.7468.88970313.489500.580703.308802.09480HepG2STIP1
KLHL18ENSG00000114648.7343.45450255.933900.424202.236801.48300HepG2TIA1
KLHL18ENSG00000114648.7612.64950343.089600.836408.118207.04370HepG2U2AF1
KLHL18ENSG00000114648.7598.39180309.660300.950302.613201.65640HepG2U2AF2
KLHL18ENSG00000114648.7784.73710416.424700.914104.600303.50200HepG2UBE2L3
KLHL18ENSG00000114648.7449.29160300.433900.580505.350904.43060HepG2UPF1
KLHL18ENSG00000114648.7658.49080290.059001.1827021.3621019.93040HepG2UTP3
KLHL18ENSG00000114648.7524.76550277.671100.918206.616605.02840HepG2XRCC6
KLHL18ENSG00000114648.7237.24450400.48290-0.755404.280103.38400HepG2XRN2
KLHL18ENSG00000114648.7577.89870330.421500.8064011.8788010.94240HepG2ZNF622
KLHL18ENSG00000114648.72222.464101844.706900.268702.521201.33850K562APOBEC3C
KLHL18ENSG00000114648.74140.221301868.022401.1481028.8706027.17860K562AQR
KLHL18ENSG00000114648.7497.82820657.51490-0.401402.559201.55320K562CCAR1
KLHL18ENSG00000114648.72273.018401345.440400.756405.405303.85970K562CNOT7
KLHL18ENSG00000114648.73446.924902569.963100.423506.907805.38630K562CELF1
KLHL18ENSG00000114648.72106.551001510.711900.479607.304606.31510K562DDX47
KLHL18ENSG00000114648.71711.143401016.511700.751209.852508.02940K562EFTUD2
KLHL18ENSG00000114648.7967.639201667.32400-0.7850017.9862016.38510K562EIF2S2
KLHL18ENSG00000114648.7982.58670660.618000.572707.493806.19350K562EIF3G
KLHL18ENSG00000114648.71023.28820720.008800.507004.768803.69120K562EIF4A3
KLHL18ENSG00000114648.7633.97940847.82800-0.419302.435501.63090K562FMR1
KLHL18ENSG00000114648.71673.22230748.774801.1599035.2557033.22950K562FXR1
KLHL18ENSG00000114648.7390.44920559.20740-0.518202.770402.06160K562G3BP2
KLHL18ENSG00000114648.7707.577701019.13270-0.526404.295002.49300K562GEMIN5
KLHL18ENSG00000114648.7531.73140795.35740-0.580902.811902.01070K562GPKOW
KLHL18ENSG00000114648.71850.956202221.92000-0.263502.039701.38470K562GRSF1
KLHL18ENSG00000114648.71142.060401750.50660-0.616107.535206.24040K562HSPD1
KLHL18ENSG00000114648.71412.75610786.892100.8442014.4776012.43490K562MAGOH
KLHL18ENSG00000114648.71058.13290785.246200.430204.093902.95500K562MATR3
KLHL18ENSG00000114648.71389.26440700.079700.9886017.2771014.72430K562PCBP2
KLHL18ENSG00000114648.71385.822901105.340700.326202.987802.15470K562POLR2G
KLHL18ENSG00000114648.71179.515301465.76510-0.313502.220001.48780K562PPIG
KLHL18ENSG00000114648.71778.46100989.185800.8462012.3014010.71330K562PRPF8
KLHL18ENSG00000114648.7464.92220765.73540-0.719907.345405.73770K562PSIP1
KLHL18ENSG00000114648.71315.60800764.539300.7830013.0762011.69020K562PTBP1
KLHL18ENSG00000114648.72768.575702280.976100.279402.621101.82730K562PUF60
KLHL18ENSG00000114648.71021.69380732.923900.479104.329403.24970K562RBM22
KLHL18ENSG00000114648.71015.66800771.326800.396902.909601.78350K562NELFE
KLHL18ENSG00000114648.71369.56450984.924400.475504.985403.53130K562SAFB
KLHL18ENSG00000114648.71487.331201264.951300.233502.091101.37560K562SF3A3
KLHL18ENSG00000114648.71047.80010581.514600.849408.952207.36350K562SF3B4
KLHL18ENSG00000114648.71255.04380789.350400.668902.696201.48670K562SNRNP200
KLHL18ENSG00000114648.71973.668601295.963400.6068015.7500013.78050K562SRPK2
KLHL18ENSG00000114648.71383.01670749.540000.8836015.8207014.13330K562SRSF1
KLHL18ENSG00000114648.71106.792201990.20650-0.8465014.6013011.72150K562SUCLG1
KLHL18ENSG00000114648.71442.420601108.702700.379503.942202.95990K562SYNCRIP
KLHL18ENSG00000114648.71040.78870758.504600.456303.709802.88550K562TARDBP
KLHL18ENSG00000114648.7898.00810731.684000.295402.021101.32850K562TIA1
KLHL18ENSG00000114648.7745.93950542.095600.460402.896101.77430K562U2AF1
KLHL18ENSG00000114648.7965.048101359.34590-0.494204.957204.02600K562UPF1
KLHL18ENSG00000114648.7880.472001163.15570-0.401703.761402.74030K562WDR3
KLHL18ENSG00000114648.71446.241901209.503800.257802.979102.10080K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHL18 is not available on ENCORE database.





12 RBPs can affect the splicing of KLHL18 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLHL18ENSG00000114648.7chr3+4732870947328838473244484732458447361142473612730.251000.000090.00293includedK562SRSF1
SEKLHL18ENSG00000114648.7chr3+473287094732883847324448473245844736114247361273-0.177000.003180.05214excludedK562SF3B4
SEKLHL18ENSG00000114648.7chr3+473389624733916247324448473245844736114247361273-0.066000.001490.05033excludedK562PRPF8
SEKLHL18ENSG00000114648.7chr3+4734429147344475473244484732458447361142473612730.142000.000320.05209includedK562MATR3
SEKLHL18ENSG00000114648.7chr3+4733905147339162473244064732458447361142473612730.077000.000340.07888includedK562PUM1
SEKLHL18ENSG00000114648.7chr3+473287094732883847324448473245844736114247361273-0.153000.003640.04106excludedHepG2U2AF2
SEKLHL18ENSG00000114648.7chr3+473780094737824747371440473716394738206147382166-0.088000.007020.06135excludedK562AQR
SEKLHL18ENSG00000114648.7chr3+4732870947328838473244484732458447361142473612730.365000.000000.00358includedK562KHSRP
SEKLHL18ENSG00000114648.7chr3+4732870947328838473244484732458447361142473612730.347000.001670.06119includedHepG2MATR3
SEKLHL18ENSG00000114648.7chr3+4732870947328838473244484732458447361142473612730.337000.000000.00004includedK562TARDBP
SEKLHL18ENSG00000114648.7chr3+4732870947328838473244484732458447361142473612730.373000.000000.00001includedK562PTBP1
A3SSKLHL18ENSG00000114648.7chr3+473780094737824747378024473782474737617247376309-0.239000.000430.04173shorterK562AGGF1
A3SSKLHL18ENSG00000114648.7chr3+4737800947378247473780244737824747376172473763090.244000.000190.05494longerK562DROSHA
A3SSKLHL18ENSG00000114648.7chr3+4737800947378247473780244737824747376172473763090.220000.008830.04753longerK562AQR
A3SSKLHL18ENSG00000114648.7chr3+4738204647382166473820614738216647378009473782470.057000.004470.02619longerK562AQR
A3SSKLHL18ENSG00000114648.7chr3+4737615247376309473761724737630947374656473748070.147000.000000.00002longerK562AQR
MXEKLHL18ENSG00000114648.7chr3+47374646473748074737800947378247473714404737163947382061473821660.149000.000690.006581includedK562AQR
MXEKLHL18ENSG00000114648.7chr3+4738206147382166473842084738432047378024473782474738504447386067-0.103000.015840.091452includedK562AQR
MXEKLHL18ENSG00000114648.7chr3+4732870947328838473390384733916247324448473245844736114247361273-0.229000.000210.027042includedK562PUM1
MXEKLHL18ENSG00000114648.7chr3+4732870947328908473390384733916247324448473245844736114247361273-0.230000.000290.032192includedK562PUM1
MXEKLHL18ENSG00000114648.7chr3+47328709473288384733896247339162473244484732458447361142473612730.142000.004860.073081includedK562PRPF8
MXEKLHL18ENSG00000114648.7chr3+47328709473287914733896247339162473244484732458447361142473612730.173000.003360.057231includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHL18 is not avaliable on ENCORE database.