C1RL

General Information

Gene Name       : C1RL
Gene ID             : ENSG00000139178.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C1RL)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C1RLENSG00000139178.1010.287.178.72ENCSR000AEF
HepG2C1RLENSG00000139178.1023.5122.8423.18ENCSR985KAT
K562C1RLENSG00000139178.105.275.935.60ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C1RL is not avaliable on ENCORE database.



Proteins bound to RNA
  • C1RL RNA is bound by 20 proteins.  







eCLIP assay for C1RL is not avaliable on ENCORE database.





20 proteins are bound to C1RL RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1272522957252386-3'-UTR,CDS,intron-Distal,intron-Proximal3.666149.07209HepG2U2AF2
chr1272488347248889-3'-UTR,intron-Distal,intron-Proximal3.465476.39151HepG2FAM120A
chr1272488227248878-3'-UTR,intron-Distal3.060384.09267K562FAM120A
chr1272488117248873-3'-UTR,intron-Distal3.426136.39870HepG2AKAP1
chr1272482187248287-3'-UTR,intron-Distal4.8768917.36975HepG2PCBP2
chr1272523217252375-3'-UTR,CDS,intron-Distal,intron-Proximal4.427415.80103HepG2U2AF1
chr1272488167248894-3'-UTR,intron-Distal,intron-Proximal4.232968.17821HepG2PRPF4
chr1272487267248874-3'-UTR,intron-Distal3.158484.99723HepG2IGF2BP1
chr1272487557248883-3'-UTR,intron-Distal5.4809424.23015HepG2UPF1
chr1272481987248218-3'-UTR,intron-Distal4.1657410.06226HepG2PCBP2
chr1272488177248887-3'-UTR,intron-Distal4.616645.56287HepG2GTF2F1
chr1272481847248250-3'-UTR,intron-Distal3.941016.61524HepG2UPF1
chr1272479747248025-3'-UTR,intron-Distal3.786805.85347HepG2UPF1
chr1272481827248241-3'-UTR,intron-Distal3.683844.41670HepG2AKAP1
chr1272481137248175-3'-UTR,intron-Distal5.108449.25213HepG2UPF1
chr1272477457247818-3'-UTR,intron-Distal4.700656.52213HepG2UPF1
chr1272481697248198-3'-UTR,intron-Distal3.503847.95222HepG2PCBP2
chr1272473967247505-3'-UTR,intron-Distal5.244627.98718HepG2UPF1
chr1272617117261816-5'-UTR,CDS,intron-Distal,intron-Proximal5.197879.08822HepG2NCBP2
chr1272608407260923-CDS,intron-Distal,intron-Proximal3.002863.49720HepG2SRSF7
chr1272608917261051-CDS,intron-Distal,intron-Proximal3.317979.05887HepG2RPS3
chr1272565497256592-intron-Distal4.497304.78128HepG2SUGP2
chr1272583957258526-intron-Distal4.833595.81225K562PTBP1
chr1272581847258245-intron-Distal3.284479.52820HepG2SUGP2
chr1272589017258948-intron-Distal4.261067.80398HepG2SUGP2
chr1272584227258484-intron-Distal4.388617.57837HepG2MATR3
chr1272592487259304-intron-Distal3.396753.09339K562MATR3
chr1272592397259327-intron-Distal3.9678414.35124HepG2MATR3
chr1272571157257190-intron-Distal3.8684710.24078HepG2HNRNPL
chr1272591387259189-intron-Distal3.283258.04518HepG2SUGP2
chr1272567107256768-intron-Distal3.946836.77642HepG2SUGP2
chr1272539257253999-intron-Distal3.145183.90917HepG2PRPF4
chr1272571907257249-intron-Distal3.440956.14017HepG2HNRNPL
chr1272515217251632-intron-Distal3.759974.00430HepG2UPF1
chr1272536467253706-intron-Distal4.610214.57154HepG2FAM120A
chr1272587457258779-intron-Distal4.053547.80398HepG2SUGP2
chr1272590387259137-intron-Distal3.184123.30286HepG2PTBP1
chr1272583767258435-intron-Distal5.4862512.10180HepG2SUGP2
chr1272513577251431-intron-Distal3.303034.21858HepG2HNRNPK
chr1272585577258594-intron-Distal4.022905.28137HepG2MATR3
chr1272589747259045-intron-Distal3.136428.72315HepG2SUGP2
chr1272550597255148-intron-Distal3.205483.46849HepG2TAF15
chr1272588077258860-intron-Distal3.271418.16357HepG2SUGP2
chr1272583477258369-intron-Distal3.232183.10961HepG2MATR3
chr1272571347257235-intron-Distal3.348484.05663K562HNRNPL
chr1272584357258493-intron-Distal3.782527.75281HepG2SUGP2
chr1272588697258938-intron-Distal3.880343.68481HepG2HNRNPM
chr1272568597256911-intron-Distal3.079774.40773HepG2SUGP2
chr1272590587259138-intron-Distal6.1679712.59569HepG2MATR3
chr1272517757251827-intron-Distal3.194093.70732HepG2HNRNPC
chr1272600557260072-intron-Distal3.262233.63132HepG2HNRNPC
chr1272590537259138-intron-Distal3.7237710.18635HepG2SUGP2
chr1272592247259298-intron-Distal3.6418317.83375HepG2SUGP2
chr1272590847259124-intron-Distal3.843293.06015K562MATR3
chr1272535627253639-intron-Distal4.549106.06839HepG2PRPF4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C1RL is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C1RL is not available on ENCORE database.

  • 125 RBPs can affect the levels of C1RL.  








The Knockdown/knockout RNA-Seq assay for C1RL is not available on ENCORE database.





125 RBPs can affect the gene expression of C1RL :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C1RLENSG00000139178.61146.561401564.58570-0.448507.984907.06090HepG2ACO1
C1RLENSG00000139178.61781.914802493.28510-0.484603.861403.24850HepG2AKAP1
C1RLENSG00000139178.61489.64670863.232700.787003.529301.65100HepG2APOBEC3C
C1RLENSG00000139178.61476.891602030.27360-0.459108.401307.31330HepG2AUH
C1RLENSG00000139178.61237.19700898.638100.461203.222002.25060HepG2BCLAF1
C1RLENSG00000139178.6765.855001140.73460-0.574805.924105.08820HepG2BOP1
C1RLENSG00000139178.62995.407401886.369300.667006.190504.70190HepG2CCAR1
C1RLENSG00000139178.61147.765901564.13550-0.446508.526907.48320HepG2CKAP4
C1RLENSG00000139178.62397.028901047.259801.1945026.3648024.51870HepG2CPSF6
C1RLENSG00000139178.61531.863401190.629700.363504.293503.02790HepG2YBX3
C1RLENSG00000139178.62834.054101855.108600.6113020.4095018.74250HepG2DAZAP1
C1RLENSG00000139178.6949.288001192.25990-0.328803.314402.04850HepG2DDX1
C1RLENSG00000139178.62286.493301460.507000.646609.516908.33920HepG2DDX21
C1RLENSG00000139178.61143.360001429.48280-0.322202.811901.88940HepG2DDX24
C1RLENSG00000139178.61591.70110951.424500.742306.228704.38260HepG2DDX27
C1RLENSG00000139178.61289.698902388.34530-0.8890012.9888011.72740HepG2DDX3X
C1RLENSG00000139178.61521.524002051.71630-0.431303.089202.43980HepG2DDX6
C1RLENSG00000139178.61415.489601127.577500.328002.635101.67650HepG2DHX30
C1RLENSG00000139178.61891.935701496.856000.337804.674103.83520HepG2DKC1
C1RLENSG00000139178.61576.557101158.805800.444008.713607.63400HepG2DNAJC2
C1RLENSG00000139178.61938.983501412.737100.456704.150803.04490HepG2EEF2
C1RLENSG00000139178.62892.735902179.571300.408303.053702.38280HepG2EIF4A3
C1RLENSG00000139178.61494.828602122.19030-0.505603.375302.61830HepG2EIF4B
C1RLENSG00000139178.61381.985701830.18870-0.405206.075304.92230HepG2EIF4G1
C1RLENSG00000139178.63188.048902331.107700.451609.208008.21740HepG2ETF1
C1RLENSG00000139178.61390.02290995.160000.482004.903102.19200HepG2EXOSC5
C1RLENSG00000139178.61501.221102136.57070-0.509204.550203.58020HepG2FIP1L1
C1RLENSG00000139178.61142.32400846.386600.432502.739301.47710HepG2FKBP4
C1RLENSG00000139178.6888.650501483.75290-0.7396011.347609.80200HepG2FUBP3
C1RLENSG00000139178.61628.475302199.20990-0.433503.733802.93950HepG2FXR1
C1RLENSG00000139178.62649.091601187.159501.1579020.3366018.77560HepG2GPKOW
C1RLENSG00000139178.61489.985501180.265900.336102.718102.07710HepG2HNRNPA1
C1RLENSG00000139178.62035.862501704.903700.255802.981502.01670HepG2HNRNPA2B1
C1RLENSG00000139178.62341.056401312.848800.8344014.9423013.45640HepG2HNRNPC
C1RLENSG00000139178.61961.828801551.609500.338304.852003.93560HepG2HNRNPF
C1RLENSG00000139178.61239.495102065.85480-0.7370010.523209.23940HepG2HNRNPK
C1RLENSG00000139178.61451.638801132.927300.357502.580001.96850HepG2HNRNPLL
C1RLENSG00000139178.61150.776401473.99230-0.357103.453702.39950HepG2HNRNPM
C1RLENSG00000139178.62179.567201527.892400.512407.424706.29150HepG2IGF2BP1
C1RLENSG00000139178.61755.132501332.160300.397707.978706.80160HepG2ILF2
C1RLENSG00000139178.62823.365001992.377200.502803.893602.90460HepG2LARP4
C1RLENSG00000139178.61200.244402212.27270-0.8822011.3185010.10630HepG2MATR3
C1RLENSG00000139178.62181.982801155.419100.917108.898907.13520HepG2MTPAP
C1RLENSG00000139178.61687.710002264.36910-0.424003.340002.64590HepG2NCBP2
C1RLENSG00000139178.62495.195501839.522500.439706.587105.41540HepG2NOL12
C1RLENSG00000139178.6409.74500844.75510-1.043804.405103.27000HepG2PABPC1
C1RLENSG00000139178.61090.620102004.75830-0.8783025.4777023.95190HepG2PCBP1
C1RLENSG00000139178.6704.812701553.97140-1.1406028.0436026.08950HepG2PRPF4
C1RLENSG00000139178.6525.39010784.35380-0.578104.493703.49020HepG2PRPF8
C1RLENSG00000139178.62597.526401755.988400.564808.192207.23920HepG2PUF60
C1RLENSG00000139178.61832.994802209.36370-0.269402.886502.25160HepG2QKI
C1RLENSG00000139178.6609.852101579.51250-1.3729013.5993012.14820HepG2RAVER1
C1RLENSG00000139178.61420.82810990.536400.520404.223302.06870HepG2RBM14
C1RLENSG00000139178.61803.201502145.11200-0.250502.225901.44670HepG2RBM15
C1RLENSG00000139178.6924.840501948.35760-1.0750032.1140030.73110HepG2RBM22
C1RLENSG00000139178.61020.598402005.07530-0.9742021.5010019.72780HepG2RBM25
C1RLENSG00000139178.62285.737301671.463700.451404.782803.91750HepG2RPLP0
C1RLENSG00000139178.61943.06890927.649801.0666012.7099011.05330HepG2RPS3A
C1RLENSG00000139178.6380.92200775.87900-1.0263010.861709.46090HepG2RRP9
C1RLENSG00000139178.61391.254501119.982400.312802.230301.38270HepG2SERBP1
C1RLENSG00000139178.6727.563501880.77600-1.3702019.7168017.86890HepG2SF3A3
C1RLENSG00000139178.6778.581201121.37940-0.526404.824703.91460HepG2SF3B1
C1RLENSG00000139178.61656.382502123.87650-0.358704.658303.92160HepG2SF3B4
C1RLENSG00000139178.61181.796701354.37500-0.196601.998001.43720HepG2SMN1
C1RLENSG00000139178.61182.480002200.56800-0.8961032.1045030.88790HepG2SRFBP1
C1RLENSG00000139178.61039.900602216.80880-1.0920041.5587040.20390HepG2SRSF1
C1RLENSG00000139178.61984.465401524.405100.380406.044305.07800HepG2SRSF7
C1RLENSG00000139178.62655.273601910.561300.4748010.673109.79380HepG2SSB
C1RLENSG00000139178.61635.151101971.79000-0.270103.819503.11010HepG2SUCLG1
C1RLENSG00000139178.61638.455102319.30850-0.501403.659602.11780HepG2SUGP2
C1RLENSG00000139178.61480.504901012.269800.548404.312903.49490HepG2SUPV3L1
C1RLENSG00000139178.61509.777201992.39210-0.400205.660504.90830HepG2TAF15
C1RLENSG00000139178.61876.511601104.229700.7649011.3558010.03670HepG2TARDBP
C1RLENSG00000139178.6504.46320678.47240-0.427502.522101.56450HepG2TFIP11
C1RLENSG00000139178.6853.478401827.56190-1.0985020.2780018.52340HepG2U2AF1
C1RLENSG00000139178.6304.69420597.96040-0.9727010.282508.82160HepG2UCHL5
C1RLENSG00000139178.62309.994201667.961300.4697010.280109.08360HepG2UPF1
C1RLENSG00000139178.62396.731801714.427400.483209.206707.42990HepG2UTP18
C1RLENSG00000139178.6979.621701610.35030-0.7171017.1573015.85600HepG2UTP3
C1RLENSG00000139178.61962.954101533.634900.356006.153805.21410HepG2ZC3H8
C1RLENSG00000139178.6268.47850142.737500.911303.319601.43650K562ADAR
C1RLENSG00000139178.6118.63680328.02360-1.467206.210505.41230K562AGGF1
C1RLENSG00000139178.6186.72770360.37350-0.948602.853901.85260K562AKAP8
C1RLENSG00000139178.6137.08130341.30500-1.316005.694704.73740K562AKAP8L
C1RLENSG00000139178.6189.56900358.07630-0.917503.675802.61130K562ATP5C1
C1RLENSG00000139178.6303.40230154.489200.973606.387005.05160K562BOP1
C1RLENSG00000139178.6293.87530183.768500.677203.558401.90850K562BUD13
C1RLENSG00000139178.6261.96240139.767600.906205.626403.98400K562CCAR1
C1RLENSG00000139178.6468.42890223.215701.069304.626903.21070K562CNOT7
C1RLENSG00000139178.6637.15860421.424700.596305.616104.22400K562CELF1
C1RLENSG00000139178.6218.46450296.04830-0.438402.336801.72980K562DDX47
C1RLENSG00000139178.6174.41260367.38400-1.074804.473903.32280K562DKC1
C1RLENSG00000139178.6194.21070128.959600.590602.705901.51640K562EIF2S1
C1RLENSG00000139178.6379.63500248.583400.610804.618203.71850K562EIF2S2
C1RLENSG00000139178.6190.46840122.674400.634602.659701.85550K562EIF4A3
C1RLENSG00000139178.6354.65360201.689900.814204.635502.48260K562ESF1
C1RLENSG00000139178.6331.64730223.282400.570703.592902.12210K562EXOSC5
C1RLENSG00000139178.6328.29130167.145500.973807.084305.68670K562FMR1
C1RLENSG00000139178.6284.45940141.678601.005506.600805.12820K562FTO
C1RLENSG00000139178.6322.07480182.489800.819504.636702.76490K562GEMIN5
C1RLENSG00000139178.6308.18210205.242200.586403.722102.40830K562GLRX3
C1RLENSG00000139178.6396.52860156.817901.3382013.8929012.08800K562GPKOW
C1RLENSG00000139178.6432.65550208.958401.049906.518004.14680K562HNRNPAB
C1RLENSG00000139178.6476.48070166.597501.5160019.4819017.97670K562HNRNPC
C1RLENSG00000139178.6219.02770148.789300.557702.363001.32180K562HNRNPF
C1RLENSG00000139178.6407.53460267.558600.607004.364103.00140K562HNRNPL
C1RLENSG00000139178.6343.87370233.927600.555703.651502.62490K562HNRNPU
C1RLENSG00000139178.6362.61080257.111000.495902.648001.86910K562HSPD1
C1RLENSG00000139178.6403.74220203.957300.985105.151603.16550K562ILF2
C1RLENSG00000139178.6164.07530362.27440-1.142704.367003.30010K562KIF1C
C1RLENSG00000139178.6223.02130133.922100.735702.875701.91990K562KRR1
C1RLENSG00000139178.6169.96070346.73340-1.028602.334801.37500K562MAK16
C1RLENSG00000139178.6160.24770405.82990-1.340604.702203.45320K562MBNL1
C1RLENSG00000139178.6325.55360153.074901.088609.057407.40210K562METAP2
C1RLENSG00000139178.6576.14790365.382900.656905.343303.78080K562MSI2
C1RLENSG00000139178.6376.18110215.785000.801706.079304.91870K562MTPAP
C1RLENSG00000139178.693.05260284.45170-1.612105.131603.80460K562NAA15
C1RLENSG00000139178.6463.75140239.759200.9517012.1661010.75290K562NSUN2
C1RLENSG00000139178.6475.89830214.446601.149907.402405.40590K562PABPC1
C1RLENSG00000139178.694.06850175.20600-0.897302.501101.57290K562PABPN1
C1RLENSG00000139178.676.51890127.11900-0.732302.387401.48220K562PCBP2
C1RLENSG00000139178.644.59930177.12050-1.989605.736604.65400K562PRPF8
C1RLENSG00000139178.6677.76550389.786100.7980010.350808.46580K562PUM2
C1RLENSG00000139178.6129.19950338.61260-1.390005.704604.95860K562PUS1
C1RLENSG00000139178.699.12530329.81780-1.734307.770706.80770K562RBM15
C1RLENSG00000139178.6191.70380133.060900.526702.127501.39450K562RBM22
C1RLENSG00000139178.6233.80470140.042700.739303.964002.62550K562NELFE
C1RLENSG00000139178.6333.01680203.357800.711502.962001.38990K562SBDS
C1RLENSG00000139178.671.31380160.27620-1.168303.128901.82580K562SF1
C1RLENSG00000139178.6313.81040236.577100.407502.188901.45640K562SF3A3
C1RLENSG00000139178.651.1512088.06940-0.783902.207801.44550K562SF3B4
C1RLENSG00000139178.6272.99530153.949700.826305.171403.40960K562SLBP
C1RLENSG00000139178.6100.24690183.99610-0.876102.487101.34810K562SNRNP200
C1RLENSG00000139178.6307.00230176.975300.794603.879901.91120K562SRP68
C1RLENSG00000139178.6417.01470199.038201.067005.081402.86100K562STIP1
C1RLENSG00000139178.6120.16400218.50700-0.862705.068803.95010K562SYNCRIP
C1RLENSG00000139178.6202.47240137.738700.555702.294001.64670K562TARDBP
C1RLENSG00000139178.6268.03490143.672800.899504.977003.68750K562TIAL1
C1RLENSG00000139178.632.8892082.11670-1.320103.906402.56280K562U2AF1
C1RLENSG00000139178.646.8304084.77360-0.856202.377401.63320K562U2AF2
C1RLENSG00000139178.6738.28200421.646400.8080010.102807.65150K562UBE2L3
C1RLENSG00000139178.6335.26900181.420100.885905.359903.89980K562UCHL5
C1RLENSG00000139178.6613.81740254.221501.2716023.1775021.34040K562UPF1
C1RLENSG00000139178.6156.49740343.18470-1.132803.480101.97310K562UTP18
C1RLENSG00000139178.6336.95220217.529700.631202.158901.38720K562WDR3
C1RLENSG00000139178.6313.53730184.852200.762203.725302.24700K562XRN2
C1RLENSG00000139178.6463.32090289.774600.677004.877403.68250K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C1RL is not available on ENCORE database.





6 RBPs can affect the splicing of C1RL :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC1RLENSG00000139178.6chr12-726084672610757254493725468372617057261834-0.091000.000440.03199excludedHepG2RBM22
SEC1RLENSG00000139178.6chr12-726084672610757254493725468372617057261834-0.067000.000150.01802excludedHepG2DDX3X
SEC1RLENSG00000139178.6chr12-726084672610757254493725468372617057261834-0.191000.000130.03366excludedHepG2UCHL5
SEC1RLENSG00000139178.6chr12-726084672610757254493725468372617057261834-0.088000.000010.00087excludedHepG2MATR3
SEC1RLENSG00000139178.6chr12-726084672610757254493725468372617057261834-0.254000.000000.00000excludedHepG2SRSF1
SEC1RLENSG00000139178.6chr12-725249672526227252281725235672544937254683-0.147000.004900.08706excludedHepG2SRSF1
SEC1RLENSG00000139178.6chr12-726084672610757254493725468372617057261834-0.107000.000000.00002excludedHepG2PCBP1
A3SSC1RLENSG00000139178.6chr12-7252281725240372522817252356725249672526220.248000.000650.06335longerHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C1RL is not avaliable on ENCORE database.