PPP2R2D

General Information

Gene Name       : PPP2R2D
Gene ID             : ENSG00000175470.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPP2R2D)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPP2R2DENSG00000175470.1911.4013.6412.52ENCSR000AEF
HepG2PPP2R2DENSG00000175470.1924.3427.2725.80ENCSR985KAT
K562PPP2R2DENSG00000175470.1917.0518.0317.54ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPP2R2D is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPP2R2D RNA is bound by 36 proteins.  







eCLIP assay for PPP2R2D is not avaliable on ENCORE database.





36 proteins are bound to PPP2R2D RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10133761085133761203+3'-UTR,CDS,intron-Proximal3.419177.95442HepG2GRWD1
chr10133772750133772847+3'-UTR3.592124.99837HepG2XPO5
chr10133770079133770139+3'-UTR5.238137.62570HepG2CSTF2
chr10133761288133761347+3'-UTR,CDS,intron-Proximal4.938586.92731HepG2PRPF8
chr10133770139133770179+3'-UTR3.452973.31721HepG2CSTF2
chr10133771024133771086+3'-UTR3.335233.20028K562TARDBP
chr10133770822133770960+3'-UTR3.456304.85269HepG2SRSF7
chr10133769318133769396+3'-UTR,CDS4.134223.30829HepG2CSTF2
chr10133769212133769294+3'-UTR,CDS4.323023.50219HepG2CSTF2
chr10133769412133769481+3'-UTR,CDS4.7142417.94032K562PUM2
chr10133769239133769300+3'-UTR,CDS3.303806.13981HepG2CSTF2T
chr10133770086133770135+3'-UTR4.402215.62460K562CSTF2T
chr10133770712133770776+3'-UTR4.161183.34609K562TARDBP
chr10133770818133770920+3'-UTR5.8092111.47680K562EIF4G2
chr10133770179133770261+3'-UTR3.181084.27513HepG2CSTF2
chr10133770944133771024+3'-UTR5.043327.52645K562TARDBP
chr10133761110133761195+3'-UTR,CDS,intron-Proximal4.366235.70529K562GRWD1
chr10133770803133770857+3'-UTR4.865156.23114K562TARDBP
chr10133770857133770944+3'-UTR5.6083111.85065K562TARDBP
chr10133771020133771128+3'-UTR3.043184.34058HepG2DROSHA
chr10133770862133770916+3'-UTR3.031944.09672HepG2SF3B4
chr10133773040133773136+3'-UTR3.815545.09669HepG2QKI
chr10133771670133771756+3'-UTR4.241713.60305HepG2SF3B4
chr10133770976133771096+3'-UTR4.2480813.53984K562EIF4G2
chr10133769116133769212+3'-UTR,CDS,intron-Proximal4.204038.04909HepG2CSTF2
chr10133772218133772279+3'-UTR3.901373.28989K562RBM15
chr10133761033133761085+3'-UTR,CDS,intron-Proximal3.377614.25541HepG2GRWD1
chr10133770916133770957+3'-UTR3.183533.06338HepG2SF3B4
chr10133769903133769957+3'-UTR3.493494.05766HepG2CSTF2
chr10133757444133757553+5'-UTR,CDS,intron-Distal,intron-Proximal3.6828913.74275HepG2U2AF2
chr10133757370133757504+5'-UTR,CDS,intron-Distal,intron-Proximal3.417448.55250K562KHSRP
chr10133754149133754231+5'-UTR,CDS,intron-Proximal3.612428.70001HepG2PRPF8
chr10133758868133758897+5'-UTR,CDS3.658505.10442K562YBX3
chr10133758913133758966+5'-UTR,CDS,intron-Proximal3.533783.57857HepG2BCLAF1
chr10133758906133758962+5'-UTR,CDS3.337604.27261HepG2GRWD1
chr10133754114133754195+5'-UTR,CDS3.679564.82082K562ZNF622
chr10133757439133757533+5'-UTR,CDS,intron-Distal,intron-Proximal4.528483.84661K562U2AF1
chr10133757447133757540+5'-UTR,CDS,intron-Distal,intron-Proximal4.4475510.04945K562U2AF2
chr10133763768133763871+intron-Distal3.419125.10467K562SAFB2
chr10133765630133765677+intron-Distal4.763636.62122HepG2RBFOX2
chr10133761972133762040+intron-Distal5.1667817.26777K562UCHL5
chr10133762042133762097+intron-Distal4.344754.67377K562YWHAG
chr10133762720133762782+intron-Distal3.291683.65070K562SLTM
chr10133755040133755134+intron-Distal5.0232622.20836K562GTF2F1
chr10133768155133768231+intron-Distal3.823006.60399K562CSTF2T
chr10133752032133752106+intron-Distal4.251443.67656K562U2AF2
chr10133766286133766317+intron-Distal4.896825.57466K562AKAP8L
chr10133755064133755132+intron-Distal5.116775.96444HepG2PCBP2
chr10133762298133762372+intron-Distal4.558024.95501K562YWHAG
chr10133764123133764206+intron-Distal4.094596.61895K562ZNF622
chr10133765415133765505+intron-Distal4.598244.14527K562SLTM
chr10133766563133766615+intron-Distal5.8286113.41722K562AKAP8L
chr10133764132133764212+intron-Distal4.3474819.19538K562UCHL5
chr10133766710133766797+intron-Distal4.074064.11145K562FUS
chr10133766553133766612+intron-Distal4.723684.14056K562EWSR1
chr10133764593133764626+intron-Distal3.994805.85226K562UCHL5
chr10133764677133764721+intron-Distal3.655983.84914K562SLTM
chr10133766162133766239+intron-Distal5.5853912.55897HepG2CSTF2T
chr10133761334133761421+intron-Distal,intron-Proximal3.433139.05903K562UCHL5
chr10133767201133767249+intron-Distal4.527895.44892HepG2FAM120A
chr10133765806133765891+intron-Distal4.0464613.45272HepG2RBFOX2
chr10133766673133766754+intron-Distal6.3253819.07803K562AKAP8L
chr10133767552133767600+intron-Distal3.331383.58549K562NONO
chr10133762040133762104+intron-Distal4.6667810.38007K562UCHL5
chr10133763968133764047+intron-Distal3.504245.65306K562ZNF622
chr10133757334133757384+intron-Distal,intron-Proximal3.911973.22073HepG2KHSRP
chr10133766285133766329+intron-Distal3.818336.48652HepG2CSTF2T
chr10133762286133762355+intron-Distal3.934525.26073HepG2HLTF
chr10133766050133766087+intron-Distal3.345823.48223HepG2RBFOX2
chr10133764119133764195+intron-Distal4.836775.51981K562YWHAG
chr10133766574133766631+intron-Distal3.826216.45701K562CSTF2T
chr10133764145133764226+intron-Distal3.947667.26608K562SLTM
chr10133766571133766626+intron-Distal5.043178.83237HepG2CSTF2T
chr10133762118133762223+intron-Distal4.023668.77491K562SLTM
chr10133765971133766034+intron-Distal5.5377411.23022HepG2RBFOX2
chr10133766999133767095+intron-Distal4.270538.00213K562CSTF2T
chr10133767071133767096+intron-Distal4.163674.10339HepG2CSTF2T
chr10133765524133765594+intron-Distal3.791023.17740K562CSTF2T
chr10133767072133767184+intron-Distal4.323407.00469K562NONO
chr10133767229133767299+intron-Distal3.693608.97207HepG2CSTF2T
chr10133766390133766413+intron-Distal4.093054.22598K562CSTF2T
chr10133767908133767966+intron-Distal4.614176.40241K562NONO
chr10133761922133762029+intron-Distal4.077094.70608K562YWHAG
chr10133757313133757370+intron-Distal3.811446.41553K562KHSRP
chr10133761917133761972+intron-Distal4.2814010.82143K562UCHL5
chr10133762399133762455+intron-Distal3.921425.71515K562SLTM
chr10133766984133767047+intron-Distal3.111795.89444HepG2CSTF2T
chr10133763910133763959+intron-Distal4.022823.55849K562YWHAG
chr10133766377133766411+intron-Distal4.242167.37643K562AKAP8L
chr10133765902133765971+intron-Distal5.6290010.69187HepG2RBFOX2
chr10133755053133755177+intron-Distal3.749457.29030K562CSTF2T
chr10133764514133764531+intron-Distal3.471834.22563K562UCHL5
chr10133764120133764217+intron-Distal4.535055.13243HepG2GRWD1
chr10133766743133766777+intron-Distal4.130054.48935K562CSTF2T
chr10133766151133766210+intron-Distal5.040926.62122HepG2RBFOX2
chr10133766569133766609+intron-Distal4.404265.15564HepG2FAM120A
chr10133763948133764025+intron-Distal3.809246.43014K562SLTM
chr10133764212133764273+intron-Distal5.9196015.25359K562UCHL5
chr10133765938133766007+intron-Distal4.8710612.85068K562AKAP8L
chr10133766209133766245+intron-Distal3.922543.17740K562CSTF2T
chr10133767016133767144+intron-Distal4.3188310.76744K562EWSR1
chr10133755056133755130+intron-Distal5.109327.28703HepG2GTF2F1
chr10133762109133762196+intron-Distal4.9167414.36289K562UCHL5
chr10133763966133764071+intron-Distal4.3230717.65347K562UCHL5
chr10133755096133755161+intron-Distal3.507673.74485K562DROSHA
chr10133755029133755152+intron-Distal4.060646.24931HepG2PRPF4
chr10133764466133764561+intron-Distal3.228193.67498K562SAFB2
chr10133764273133764304+intron-Distal5.173237.60619K562UCHL5
chr10133766576133766630+intron-Distal4.455644.72743K562NONO
chr10133766157133766230+intron-Distal4.659084.42691HepG2GTF2F1
chr10133764001133764095+intron-Distal3.635695.99043HepG2GRWD1
chr10133769073133769116+intron-Distal,intron-Proximal4.207044.47016HepG2CSTF2
chr10133766144133766201+intron-Distal5.6844711.68107K562AKAP8L
chr10133767001133767079+intron-Distal4.091623.93293K562FUS
chr10133762982133763018+intron-Distal3.226343.34034HepG2HLTF
chr10133766151133766249+intron-Distal3.967045.32184HepG2PRPF4
chr10133757415133757455+intron-Distal,intron-Proximal4.459753.82050HepG2SF3B4
chr10133768955133769014+intron-Distal4.797336.21741HepG2CSTF2
chr10133754256133754319+intron-Distal,intron-Proximal4.7762119.67969K562FMR1
chr10133766744133766819+intron-Distal3.9847910.93103HepG2CSTF2T
chr10133765710133765769+intron-Distal5.246728.80058HepG2RBFOX2
chr10133762237133762286+intron-Distal3.539734.42924HepG2HLTF
chr10133768327133768386+intron-Distal4.077164.66791HepG2CSTF2
chr10133767927133767968+intron-Distal3.234833.04847HepG2CSTF2T
chr10133767255133767300+intron-Distal4.838486.10563K562AKAP8L
chr10133766201133766240+intron-Distal5.302317.80606K562AKAP8L
chr10133761923133761971+intron-Distal4.372824.04372HepG2BCLAF1
chr10133768308133768389+intron-Distal3.359025.68177HepG2CSTF2T
chr10133765943133766021+intron-Distal3.962933.57264HepG2GTF2F1
chr10133763655133763760+intron-Distal4.555386.26905K562SAFB2
chr10133766149133766238+intron-Distal5.8386415.44869HepG2FAM120A
chr10133755043133755115+intron-Distal6.096129.54749K562FASTKD2
chr10133764011133764065+intron-Distal3.090154.38249K562RBM15
chr10133768145133768245+intron-Distal3.8678013.36493HepG2CSTF2
chr10133762058133762077+intron-Distal4.030313.12746HepG2GRWD1
chr10133768553133768637+intron-Distal3.636034.80457HepG2CSTF2
chr10133758968133759022+intron-Proximal4.552628.01338K562AQR
chr10133758963133758968+intron-Proximal4.123634.98250K562AQR
chr10133769124133769178+intron-Proximal3.238315.55128HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPP2R2D is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPP2R2D is not available on ENCORE database.

  • 36 RBPs can affect the levels of PPP2R2D.  








The Knockdown/knockout RNA-Seq assay for PPP2R2D is not available on ENCORE database.





36 RBPs can affect the gene expression of PPP2R2D :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPP2R2DENSG00000175470.14527.78170826.59070-0.647204.666903.99850HepG2AKAP1
PPP2R2DENSG00000175470.14475.90780599.96710-0.334202.554001.81410HepG2AKAP8L
PPP2R2DENSG00000175470.14627.22720442.492800.503202.908001.94480HepG2BCCIP
PPP2R2DENSG00000175470.14775.43270573.082600.436203.188402.55120HepG2BOP1
PPP2R2DENSG00000175470.14379.57970490.09530-0.368702.190001.49850HepG2CALR
PPP2R2DENSG00000175470.14372.71290526.11900-0.497303.157202.42770HepG2CPSF6
PPP2R2DENSG00000175470.14831.47030596.391500.479303.112102.43810HepG2GPKOW
PPP2R2DENSG00000175470.141105.46130707.005200.644804.334902.94360HepG2GRSF1
PPP2R2DENSG00000175470.14924.43510612.747100.593208.585307.61330HepG2PCBP1
PPP2R2DENSG00000175470.14821.82080675.266600.283301.910001.37600HepG2QKI
PPP2R2DENSG00000175470.14926.47280699.944300.404403.136402.41570HepG2RPLP0
PPP2R2DENSG00000175470.14454.39720332.032700.452502.238001.52370HepG2RRP9
PPP2R2DENSG00000175470.141260.39580796.051800.662805.392104.43160HepG2SF3A3
PPP2R2DENSG00000175470.14730.62150563.340900.375002.287801.64370HepG2SF3B1
PPP2R2DENSG00000175470.14354.31140626.81660-0.823005.058803.99200HepG2SNRNP70
PPP2R2DENSG00000175470.141029.44350827.773900.314503.321502.78840HepG2SRFBP1
PPP2R2DENSG00000175470.14807.28480677.558700.252601.785901.38210HepG2SRSF1
PPP2R2DENSG00000175470.14879.67570606.165600.537203.295102.19210HepG2SRSF3
PPP2R2DENSG00000175470.14433.47640551.22510-0.346702.656402.11330HepG2SRSF9
PPP2R2DENSG00000175470.141205.23290718.710700.7457016.0348015.00950HepG2SSB
PPP2R2DENSG00000175470.14624.77330463.857800.429603.387302.84460HepG2TIAL1
PPP2R2DENSG00000175470.14363.45220255.855200.506302.799802.03520HepG2UCHL5
PPP2R2DENSG00000175470.14653.83390440.037000.571206.927205.94320HepG2ZC3H8
PPP2R2DENSG00000175470.141667.015601050.843800.665608.387507.45510K562AQR
PPP2R2DENSG00000175470.14867.77210584.649400.569606.923104.72100K562BCCIP
PPP2R2DENSG00000175470.14629.19290495.385000.344902.764801.44430K562DDX27
PPP2R2DENSG00000175470.141398.032801067.741400.388705.403304.53690K562DDX47
PPP2R2DENSG00000175470.14531.83480357.314700.573702.432501.49410K562EIF3A
PPP2R2DENSG00000175470.14651.76590422.005900.627006.961305.70840K562EIF3G
PPP2R2DENSG00000175470.14786.20250631.489500.316002.023601.50240K562HNRNPC
PPP2R2DENSG00000175470.14758.65820555.270400.450202.795501.86130K562HNRNPM
PPP2R2DENSG00000175470.141356.896801120.005100.276702.460401.68810K562KIF1C
PPP2R2DENSG00000175470.141682.100001046.578800.684508.384207.48670K562PUS1
PPP2R2DENSG00000175470.141208.770101019.814300.245102.100601.57090K562RBM15
PPP2R2DENSG00000175470.14900.96190553.494200.702805.829904.63860K562RPS19
PPP2R2DENSG00000175470.141387.77230899.428600.6256011.065409.51400K562SF3A3
PPP2R2DENSG00000175470.142174.21960576.379501.9153057.5283053.62390K562TARDBP
PPP2R2DENSG00000175470.141136.63450859.964100.402305.179104.05250K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPP2R2D is not available on ENCORE database.





13 RBPs can affect the splicing of PPP2R2D :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPP2R2DENSG00000175470.14chr10+1337574711337575011337540851337541981337575981337576490.321000.004340.06768includedK562SRSF1
SEPPP2R2DENSG00000175470.14chr10+1337574711337575071337541131337541981337575981337576490.292000.001760.03314includedK562SF3B4
SEPPP2R2DENSG00000175470.14chr10+1337483971337485101337479591337480591337535341337537000.104000.000050.05590includedK562TROVE2
SEPPP2R2DENSG00000175470.14chr10+1337483971337485101337479591337480591337535341337537000.183000.000000.00012includedK562AQR
SEPPP2R2DENSG00000175470.14chr10+1337574711337575011337540851337541981337575981337576490.346000.000490.02217includedK562FXR1
SEPPP2R2DENSG00000175470.14chr10+1337483971337485101337479591337480591337535341337537000.157000.000260.01636includedHepG2SFPQ
SEPPP2R2DENSG00000175470.14chr10+1337483971337485101337479591337480591337535341337537000.199000.000010.02225includedK562EXOSC5
SEPPP2R2DENSG00000175470.14chr10+1337483971337485101337479591337480591337535341337537000.285000.000100.02057includedHepG2RBFOX2
SEPPP2R2DENSG00000175470.14chr10+133757471133757501133754085133754198133757598133757649-0.320000.000730.09705excludedK562SRSF7
SEPPP2R2DENSG00000175470.14chr10+1337483971337485101337479591337480591337535341337537000.158000.002270.08488includedHepG2SF3B4
SEPPP2R2DENSG00000175470.14chr10+1337574711337575011337540461337541981337575981337576490.332000.001650.06841includedHepG2SF3B4
SEPPP2R2DENSG00000175470.14chr10+133757471133757501133754065133754198133757598133757649-0.293000.000100.00622excludedK562TARDBP
SEPPP2R2DENSG00000175470.14chr10+133757471133757501133754085133754198133757598133757649-0.317000.007380.09337excludedK562HNRNPC
A3SSPPP2R2DENSG00000175470.14chr10+1337574711337576491337575981337576491337541131337541980.247000.000700.04001longerK562SF3B4
A3SSPPP2R2DENSG00000175470.14chr10+1337540651337542961337540851337542961337535151337537000.117000.000000.00000longerK562AQR
A3SSPPP2R2DENSG00000175470.14chr10+1337535151337537001337535341337537001337479541337480590.127000.000300.00239longerK562AQR
A3SSPPP2R2DENSG00000175470.14chr10+133757471133757649133757598133757649133754065133754198-0.198000.001090.05207shorterK562PUS1
A3SSPPP2R2DENSG00000175470.14chr10+133757471133757649133757598133757649133754065133754198-0.264000.000200.05238shorterK562TARDBP
A5SSPPP2R2DENSG00000175470.14chr10+1337540651337542961337540651337541981337574711337575100.165000.000000.00000longerK562AQR
A5SSPPP2R2DENSG00000175470.14chr10+133754085133754308133754085133754198133757471133757510-0.077000.000780.06365shorterK562FXR1
A5SSPPP2R2DENSG00000175470.14chr10+133754085133754296133754085133754198133757471133757501-0.127000.000210.07219shorterK562TAF15

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPP2R2D is not avaliable on ENCORE database.