C4A

General Information

Gene Name       : C4A
Gene ID             : ENSG00000244731.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C4A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C4AENSG00000244731.70.200.580.39ENCSR000AEF
HepG2C4AENSG00000244731.7450.68173.99312.34ENCSR985KAT
K562C4AENSG00000244731.74.723.354.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C4A is not avaliable on ENCORE database.



Proteins bound to RNA
  • C4A RNA is bound by 17 proteins.  







eCLIP assay for C4A is not avaliable on ENCORE database.





17 proteins are bound to C4A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63197029031970435+3'-UTR,CDS4.477254.61933HepG2LARP4
chr63194985831949942+5'-UTR,CDS,intron-Distal5.950856.75859HepG2DDX3X
chr63197023631970268+CDS5.6597011.22354HepG2SND1
chr63197001631970032+CDS5.8894213.95300HepG2SND1
chr63196398331964000+CDS,intron-Proximal4.2202117.55452HepG2SND1
chr63196382231963875+CDS3.9647618.73962HepG2PPIG
chr63196356831963571+CDS4.3303856.96485HepG2SND1
chr63196351131963572+CDS,intron-Proximal3.810656.10841HepG2RPS3
chr63196886931968916+CDS6.1109410.32792HepG2SND1
chr63196236931962393+CDS4.21839400.00000HepG2SND1
chr63196239331962427+CDS4.34584400.00000HepG2SND1
chr63196230431962423+CDS3.7661327.42154HepG2RPS3
chr63196356331963572+CDS,intron-Proximal3.2953110.37782HepG2PPIG
chr63196387531963889+CDS,intron-Proximal4.3881413.26490HepG2PPIG
chr63197017531970197+CDS,intron-Proximal5.7526311.81929HepG2SND1
chr63196356231963568+CDS4.3281759.67496HepG2SND1
chr63196229931962420+CDS4.5553119.36457HepG2SDAD1
chr63196386831963888+CDS4.0557038.73351HepG2SND1
chr63196929331969327+CDS5.8454813.33040HepG2SND1
chr63196373131963741+CDS,intron-Proximal3.137766.23940HepG2PPIG
chr63196323131963311+CDS6.0377634.50040HepG2SND1
chr63195068731950693+CDS5.157448.82060HepG2SND1
chr63196382031963868+CDS3.4653645.84164HepG2SND1
chr63196386431963888+CDS4.067596.43771HepG2RPS3
chr63196350731963563+CDS3.2242413.28635HepG2PPIG
chr63196398331964000+CDS,intron-Proximal3.627126.81103HepG2PPIG
chr63196233731962426+CDS3.1145611.39380HepG2NOL12
chr63196428331964355+CDS3.445249.11498HepG2RPS3
chr63196351431963562+CDS4.4530674.84719HepG2SND1
chr63196314131963203+CDS6.5870316.44988HepG2SND1
chr63196435531964418+CDS,intron-Proximal3.8120110.86325HepG2PRPF8
chr63196373131963753+CDS,intron-Proximal4.4429256.01369HepG2SND1
chr63196172331961744+CDS5.3894210.15376HepG2SND1
chr63196376931963801+CDS4.4415917.73762HepG2SND1
chr63196380431963864+CDS3.478943.75427HepG2RPS3
chr63196380431963891+CDS,intron-Proximal3.166909.15554HepG2NOLC1
chr63196428131964351+CDS3.5626043.18104HepG2SND1
chr63195009731950172+3'-UTR,CDS,intron-Proximal6.2067411.95715HepG2DDX3X
chr63195827931958283+intron-Distal5.367214.82899K562PABPC4
chr63195827931958283+intron-Distal5.658489.57899K562WRN
chr63195828031958283+intron-Distal4.518543.36399K562NPM1
chr63195827931958284+intron-Distal4.867294.07467K562TROVE2
chr63195825631958258+intron-Distal4.091983.88823K562FMR1
chr63195827931958286+intron-Distal4.853227.38946K562RBM22
chr63195827931958286+intron-Distal4.743733.34538K562DGCR8
chr63195827931958284+intron-Distal6.304757.96631K562GNL3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C4A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C4A is not available on ENCORE database.

  • 138 RBPs can affect the levels of C4A.  








The Knockdown/knockout RNA-Seq assay for C4A is not available on ENCORE database.





138 RBPs can affect the gene expression of C4A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C4AENSG00000244731.324423.6591014828.190700.7198011.584309.87610HepG2ABCF1
C4AENSG00000244731.38786.2867015907.33330-0.8564056.0527054.18680HepG2ACO1
C4AENSG00000244731.314078.555109836.306600.517205.988704.59650HepG2ADAR
C4AENSG00000244731.37143.2552022231.00100-1.6379042.9530041.22100HepG2AKAP1
C4AENSG00000244731.323269.4148015981.999700.5419019.4709017.70600HepG2AKAP8L
C4AENSG00000244731.333769.4389018393.563900.8764016.5226014.78290HepG2ASCC1
C4AENSG00000244731.314665.5576017472.80360-0.252704.611503.76470HepG2AUH
C4AENSG00000244731.35858.4835010047.76190-0.778305.659104.29880HepG2BCCIP
C4AENSG00000244731.313764.655908729.307800.656907.157905.79130HepG2BCLAF1
C4AENSG00000244731.39700.763806495.013600.578702.853902.24650HepG2BOP1
C4AENSG00000244731.316064.0789011107.546900.532208.748606.69120HepG2BUD13
C4AENSG00000244731.37396.524009963.46110-0.429807.495906.31090HepG2CALR
C4AENSG00000244731.323833.5230015699.820700.602105.790904.35530HepG2CCAR1
C4AENSG00000244731.321143.2755017475.385500.274802.173901.48340HepG2CIRBP
C4AENSG00000244731.310233.0541015903.79120-0.6361037.7878035.97950HepG2CKAP4
C4AENSG00000244731.35117.7872015849.85300-1.6309025.8427023.59130HepG2CNOT7
C4AENSG00000244731.311239.576605962.417600.914507.513506.42590HepG2CPSF6
C4AENSG00000244731.315171.9881012208.734800.313403.397102.17370HepG2CPSF7
C4AENSG00000244731.38414.603306204.412800.439503.218802.06370HepG2CSTF2
C4AENSG00000244731.37864.3888012617.40480-0.682004.518002.63940HepG2CSTF2T
C4AENSG00000244731.317563.2387015122.828500.215702.142501.56580HepG2CELF1
C4AENSG00000244731.318069.3407016259.050200.152202.420401.72080HepG2DAZAP1
C4AENSG00000244731.310367.4816014711.96520-0.5049020.4532018.68760HepG2DDX19B
C4AENSG00000244731.317172.9820013583.382600.338203.924603.13100HepG2DDX21
C4AENSG00000244731.318645.9183011730.473700.6685011.194909.32970HepG2DDX5
C4AENSG00000244731.312558.240109552.724500.394602.958101.94940HepG2DHX30
C4AENSG00000244731.326413.2908015218.985300.7953043.0397041.20400HepG2DKC1
C4AENSG00000244731.37160.451209903.90130-0.467903.228102.47310HepG2DNAJC21
C4AENSG00000244731.39254.9880017584.47040-0.9260017.6658016.25890HepG2EIF2S1
C4AENSG00000244731.314769.8469011246.494900.393105.597003.97380HepG2EIF2S2
C4AENSG00000244731.314153.553109708.910200.543706.963905.58570HepG2EIF3D
C4AENSG00000244731.322277.7767012832.132300.7957022.7736020.31560HepG2EIF3G
C4AENSG00000244731.315826.0547019431.15230-0.296102.076901.52060HepG2EIF4A3
C4AENSG00000244731.333981.7953018922.302600.844609.890908.62920HepG2EIF4B
C4AENSG00000244731.321080.3927016042.018500.393908.101206.80950HepG2EIF4G1
C4AENSG00000244731.323369.8810015366.963600.6047010.032008.52740HepG2EIF4G2
C4AENSG00000244731.325997.9601020061.395900.373906.438005.58390HepG2ETF1
C4AENSG00000244731.37656.8782015544.23140-1.0216029.0000026.62460HepG2EWSR1
C4AENSG00000244731.39215.2515012948.27520-0.490707.889106.14560HepG2FASTKD2
C4AENSG00000244731.37723.9741014972.36960-0.9549016.9478015.32200HepG2FIP1L1
C4AENSG00000244731.311117.799605973.383500.896203.124602.04320HepG2FTO
C4AENSG00000244731.316014.4778019610.52730-0.292302.333401.69600HepG2FXR1
C4AENSG00000244731.322397.3355018188.846800.300202.173801.58140HepG2G3BP1
C4AENSG00000244731.36679.583408644.28210-0.372003.685802.63810HepG2GEMIN5
C4AENSG00000244731.320160.574806757.882001.5768027.2471025.47580HepG2GPKOW
C4AENSG00000244731.39812.5826014672.38570-0.580404.498303.08620HepG2GRSF1
C4AENSG00000244731.39525.2372013458.38440-0.498703.198601.50020HepG2GTF2F1
C4AENSG00000244731.312565.328509998.803100.329502.329901.73250HepG2HNRNPA1
C4AENSG00000244731.319168.8387014943.354600.359209.187007.67070HepG2HNRNPA2B1
C4AENSG00000244731.318183.4793010134.971800.8432035.0765033.00280HepG2HNRNPF
C4AENSG00000244731.313637.1713018424.37560-0.434105.484804.52660HepG2HNRNPK
C4AENSG00000244731.37044.7413010328.78370-0.5521010.861609.20490HepG2HNRNPM
C4AENSG00000244731.318476.295409979.958500.8885027.6022025.60740HepG2IGF2BP1
C4AENSG00000244731.322931.3071018487.571800.310702.627001.96690HepG2IGF2BP2
C4AENSG00000244731.39407.0683017353.78970-0.883403.982502.80440HepG2IGF2BP3
C4AENSG00000244731.327306.9849018597.196100.554104.915103.54420HepG2KHSRP
C4AENSG00000244731.318662.4465014541.244300.3599013.4716011.43630HepG2KIF1C
C4AENSG00000244731.322871.2477016582.264600.463803.733402.76770HepG2LARP4
C4AENSG00000244731.38432.7915012298.25810-0.544408.206006.34860HepG2LARP7
C4AENSG00000244731.39499.7707012915.67360-0.443205.275503.59510HepG2LIN28B
C4AENSG00000244731.316267.6352019617.39740-0.270101.993601.43260HepG2MAGOH
C4AENSG00000244731.315498.5145019726.33010-0.348002.727902.10060HepG2MATR3
C4AENSG00000244731.36963.3776010160.65810-0.545103.871302.63150HepG2METAP2
C4AENSG00000244731.310007.9477012115.26090-0.275703.283902.40630HepG2MSI2
C4AENSG00000244731.314375.585506579.555601.127508.978907.20650HepG2MTPAP
C4AENSG00000244731.324995.5633020190.293600.307902.344901.75990HepG2NCBP2
C4AENSG00000244731.313667.3226011120.526900.297403.069401.58050HepG2NIP7
C4AENSG00000244731.37890.443105719.216200.464202.513401.79940HepG2NSUN2
C4AENSG00000244731.315234.5504019350.93260-0.345103.743301.86070HepG2NUP35
C4AENSG00000244731.38539.8006014486.82570-0.762505.618804.32230HepG2PABPC1
C4AENSG00000244731.38116.5092010935.71180-0.430102.107201.36000HepG2PARN
C4AENSG00000244731.312557.0589018291.81120-0.5427012.2392011.10890HepG2PCBP1
C4AENSG00000244731.314581.950909854.574800.565205.037604.07170HepG2PPIL4
C4AENSG00000244731.38050.7509010998.98300-0.4502012.4494010.98450HepG2PRPF4
C4AENSG00000244731.320329.0728014204.999600.517003.488102.13130HepG2PRPF6
C4AENSG00000244731.321086.9803015390.839600.454204.765804.00940HepG2PUF60
C4AENSG00000244731.38220.6377016326.33030-0.9899037.6740035.43570HepG2PUM2
C4AENSG00000244731.325368.6947016202.638400.6467021.2249019.81190HepG2PUS1
C4AENSG00000244731.34470.2468013037.88620-1.5443020.2301018.49420HepG2RAVER1
C4AENSG00000244731.321619.1992017475.217000.306904.490703.42970HepG2RBM15
C4AENSG00000244731.33642.6359016767.55650-2.20260218.33270215.26610HepG2RBM22
C4AENSG00000244731.310090.8507018294.55740-0.8584024.4540022.56900HepG2RBM25
C4AENSG00000244731.311015.0374014829.37810-0.429004.365803.10050HepG2RBM27
C4AENSG00000244731.310689.4253015308.32350-0.518103.879402.07110HepG2RBM47
C4AENSG00000244731.317009.1048012042.078400.498106.323304.71870HepG2RCC2
C4AENSG00000244731.322762.5835020714.114500.136001.795101.33910HepG2NELFE
C4AENSG00000244731.322939.0101019292.786600.249605.253804.43890HepG2RECQL
C4AENSG00000244731.330390.9174010919.277701.4767055.4471053.37450HepG2RPLP0
C4AENSG00000244731.316732.9042013677.187100.290802.933802.11070HepG2RPS2
C4AENSG00000244731.327376.5069015915.830900.782408.663407.27580HepG2RPS3A
C4AENSG00000244731.34443.357507534.89640-0.761906.585605.42920HepG2RRP9
C4AENSG00000244731.313813.691609839.126400.489405.140604.31110HepG2SAFB2
C4AENSG00000244731.310764.4325014987.52160-0.477503.993502.43310HepG2SART3
C4AENSG00000244731.311018.6856016527.20240-0.584905.151904.21300HepG2SF3A3
C4AENSG00000244731.313000.0061019377.91930-0.5759023.7692022.32500HepG2SF3B4
C4AENSG00000244731.318990.5401014758.549600.3636013.1443011.80890HepG2SLBP
C4AENSG00000244731.38322.9472011473.49340-0.463103.222202.53650HepG2SMN1
C4AENSG00000244731.318533.8052013308.809900.477703.528602.43280HepG2SMNDC1
C4AENSG00000244731.315349.617607102.328201.1117013.7315012.01330HepG2SNRNP70
C4AENSG00000244731.37618.2529018938.23510-1.31380135.01790132.88700HepG2SRFBP1
C4AENSG00000244731.315084.8606020226.54870-0.4231015.2748014.35520HepG2SRSF1
C4AENSG00000244731.313445.730006869.664000.968702.884001.85780HepG2SRSF3
C4AENSG00000244731.317958.4921015196.874000.240802.370101.78500HepG2SRSF5
C4AENSG00000244731.322750.710409957.605201.1919065.0658062.75700HepG2SRSF7
C4AENSG00000244731.323578.3620016442.692000.5199010.047309.18710HepG2SSB
C4AENSG00000244731.314253.859709998.355100.511504.378702.85390HepG2STAU1
C4AENSG00000244731.320716.9453017282.465900.261405.066904.26830HepG2SUCLG1
C4AENSG00000244731.314226.5845024823.82620-0.803109.614007.23290HepG2SUGP2
C4AENSG00000244731.312885.016209834.016400.389702.057601.46120HepG2SUPV3L1
C4AENSG00000244731.38944.034106288.638000.508102.191201.53520HepG2TARDBP
C4AENSG00000244731.319588.8436016705.243200.229602.404901.62420HepG2TIA1
C4AENSG00000244731.316960.0976010733.778100.659907.544206.79310HepG2TIAL1
C4AENSG00000244731.319328.0798015037.100300.362105.466104.18770HepG2TUFM
C4AENSG00000244731.35893.2060012806.52450-1.1198029.5493027.41680HepG2U2AF1
C4AENSG00000244731.33106.937005808.47420-0.902707.391006.14310HepG2UCHL5
C4AENSG00000244731.319815.6200014657.109200.4349015.1599013.77660HepG2UPF1
C4AENSG00000244731.320361.0929014150.851600.5248021.9293020.47990HepG2UTP3
C4AENSG00000244731.38724.9924012825.71430-0.555804.131802.58180HepG2XRCC5
C4AENSG00000244731.311863.1269010854.601200.128101.988501.40510HepG2ZC3H8
C4AENSG00000244731.317934.7576016120.003800.153803.162802.59050HepG2ZNF622
C4AENSG00000244731.387.14520164.39280-0.915704.142403.47270K562AGGF1
C4AENSG00000244731.380.70600152.47590-0.917803.095602.48190K562AQR
C4AENSG00000244731.364.11320137.11100-1.096703.591401.40590K562DAZAP1
C4AENSG00000244731.352.96720149.14950-1.493609.156608.05550K562DDX47
C4AENSG00000244731.3193.72120108.837700.831702.832501.50410K562DDX6
C4AENSG00000244731.356.52480112.15150-0.988503.667302.72630K562EIF4A3
C4AENSG00000244731.3152.01550100.994000.589802.342301.30260K562EIF4B
C4AENSG00000244731.338.9986087.22120-1.161303.445702.16840K562FKBP4
C4AENSG00000244731.355.53670116.63210-1.070504.326103.59350K562FXR1
C4AENSG00000244731.322.0963088.21450-1.997207.398106.12670K562G3BP2
C4AENSG00000244731.373.20400119.61740-0.708402.375601.38440K562HNRNPA1
C4AENSG00000244731.375.68290132.46170-0.807503.231502.26940K562HNRNPU
C4AENSG00000244731.344.1088096.83970-1.134504.333603.27730K562MAGOH
C4AENSG00000244731.3107.12100203.36010-0.924805.068803.76110K562MBNL1
C4AENSG00000244731.371.36620184.60690-1.371105.478404.36290K562MTPAP
C4AENSG00000244731.347.7062086.15030-0.852702.254201.37540K562PCBP2
C4AENSG00000244731.330.9189077.45990-1.325003.405702.57170K562PRPF8
C4AENSG00000244731.355.5346094.09120-0.760702.338201.72090K562PTBP1
C4AENSG00000244731.3157.80810239.67000-0.602902.800901.72540K562PUM1
C4AENSG00000244731.3152.83540234.80540-0.619503.118602.10170K562PUM2
C4AENSG00000244731.393.55350169.62790-0.858502.956202.39850K562PUS1
C4AENSG00000244731.319.6769084.17190-2.096806.047003.85530K562RAVER1
C4AENSG00000244731.3152.9478087.941300.798303.222301.68820K562RBM34
C4AENSG00000244731.335.0908078.90650-1.169102.905002.06560K562RPS19
C4AENSG00000244731.331.4725079.20480-1.331503.489301.98250K562RRP9
C4AENSG00000244731.347.0926091.74840-0.962203.265402.33440K562SF3B4
C4AENSG00000244731.388.27000207.38760-1.232302.902801.94780K562SRPK2
C4AENSG00000244731.328.8766085.53200-1.566605.190803.59520K562U2AF1
C4AENSG00000244731.341.6851088.32820-1.083303.594902.67760K562U2AF2
C4AENSG00000244731.3141.43500217.44450-0.620501.929001.32110K562UPF1
C4AENSG00000244731.377.59290193.51430-1.318405.221904.09270K562WDR43
C4AENSG00000244731.3105.41350180.60650-0.776803.689702.19040K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C4A is not available on ENCORE database.






No RBPs affect the alternative splcing events of C4A on ENCORE database.





The Knockdown/knockout RNA-Seq assay for C4A is not avaliable on ENCORE database.