NLRP2

General Information

Gene Name       : NLRP2
Gene ID             : ENSG00000022556.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NLRP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NLRP2ENSG00000022556.151.791.351.57ENCSR000AEF
HepG2NLRP2ENSG00000022556.150.000.000.00ENCSR985KAT
K562NLRP2ENSG00000022556.1518.1618.9118.54ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NLRP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NLRP2 RNA is bound by 5 proteins.  







eCLIP assay for NLRP2 is not avaliable on ENCORE database.





5 proteins are bound to NLRP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195550139155501514+3'-UTR,CDS,intron-Proximal4.166843.89948K562YBX3
chr195548155255481669+5'-UTR,CDS,intron-Proximal3.305543.69481K562UCHL5
chr195549361455493698+CDS3.302113.36945K562ZNF622
chr195549348655493606+CDS,intron-Proximal3.727156.42898K562AQR
chr195548886855488965+intron-Distal3.955233.69425K562TARDBP
chr195549305055493115+intron-Distal,intron-Proximal4.038674.89208K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NLRP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NLRP2 is not available on ENCORE database.

  • 25 RBPs can affect the levels of NLRP2.  








The Knockdown/knockout RNA-Seq assay for NLRP2 is not available on ENCORE database.





25 RBPs can affect the gene expression of NLRP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NLRP2ENSG00000022556.11756.58050920.04940-0.282201.924301.43490K562AGGF1
NLRP2ENSG00000022556.111189.529501575.00600-0.405003.392102.75600K562AQR
NLRP2ENSG00000022556.111603.713102149.55290-0.422605.130203.79300K562CELF1
NLRP2ENSG00000022556.11855.100901155.46470-0.434305.679704.79650K562DDX47
NLRP2ENSG00000022556.111076.55490778.494700.467602.999701.66280K562EEF2
NLRP2ENSG00000022556.11336.87080503.74330-0.580502.541301.58080K562EIF3A
NLRP2ENSG00000022556.11563.90100818.58790-0.537704.871303.77890K562EIF4A3
NLRP2ENSG00000022556.111040.125301416.96980-0.446104.513703.55180K562GRSF1
NLRP2ENSG00000022556.11606.73900770.50550-0.344702.285901.73580K562HNRNPC
NLRP2ENSG00000022556.11870.003501106.60670-0.347002.361501.62250K562HSPD1
NLRP2ENSG00000022556.11734.310901032.00040-0.491004.972103.83700K562MAGOH
NLRP2ENSG00000022556.11927.96750731.977300.342202.181701.51180K562PRPF8
NLRP2ENSG00000022556.111131.03910925.076900.289902.675102.09080K562RBM15
NLRP2ENSG00000022556.11660.34670961.25810-0.541705.220104.02300K562RBM22
NLRP2ENSG00000022556.11789.529101011.61520-0.357602.444901.42860K562NELFE
NLRP2ENSG00000022556.11512.83190745.62870-0.540003.367702.46510K562RPS19
NLRP2ENSG00000022556.11487.73950679.21480-0.477803.420001.79050K562SDAD1
NLRP2ENSG00000022556.11628.34940792.91620-0.335602.589301.76510K562SF3B4
NLRP2ENSG00000022556.11741.69680979.45940-0.401202.639301.42430K562STAU1
NLRP2ENSG00000022556.11498.33760708.76130-0.508203.250002.14490K562SUPV3L1
NLRP2ENSG00000022556.11886.038401136.38910-0.359002.774202.05430K562UPF1
NLRP2ENSG00000022556.11740.549601009.17030-0.446503.110601.82960K562UTP3
NLRP2ENSG00000022556.11780.258701011.24460-0.374102.869702.00750K562WDR43
NLRP2ENSG00000022556.111455.724901866.15830-0.358303.404801.96330K562WRN
NLRP2ENSG00000022556.111375.090601774.26390-0.367703.371902.40570K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NLRP2 is not available on ENCORE database.





3 RBPs can affect the splicing of NLRP2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSNLRP2ENSG00000022556.11chr19+5548901255489191554891195548919155485867554859120.088000.007360.04056longerK562AQR
MXENLRP2ENSG00000022556.11chr19+55489119554891915549298455493050554858675548591255493529554950960.237000.000020.001111includedK562DROSHA
MXENLRP2ENSG00000022556.11chr19+55489012554891915549298455493050554858675548591255493529554950960.086000.013160.079011includedK562AQR
MXENLRP2ENSG00000022556.11chr19+55489119554891915549298455493050554858675548591255493529554950960.183000.008120.084601includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NLRP2 is not avaliable on ENCORE database.