PRKAR2B

General Information

Gene Name       : PRKAR2B
Gene ID             : ENSG00000005249.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PRKAR2B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRKAR2BENSG00000005249.120.000.010.01ENCSR000AEF
HepG2PRKAR2BENSG00000005249.120.010.010.01ENCSR985KAT
K562PRKAR2BENSG00000005249.1284.1794.0389.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRKAR2B is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRKAR2B RNA is bound by 32 proteins.  







eCLIP assay for PRKAR2B is not avaliable on ENCORE database.





32 proteins are bound to PRKAR2B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7106800155106800223+3'-UTR4.766594.97297K562TIA1
chr7106800328106800392+3'-UTR3.087824.65557HepG2SUB1
chr7106800511106800560+3'-UTR3.089208.08133K562PABPC4
chr7106800621106800703+3'-UTR3.9631411.44939K562IGF2BP1
chr7106800777106800810+3'-UTR3.341686.07920K562FAM120A
chr7106801804106801877+3'-UTR6.4986526.77436K562IGF2BP1
chr7106801348106801384+3'-UTR3.698809.72135K562FAM120A
chr7106800955106800996+3'-UTR3.4817427.70086K562FAM120A
chr7106801478106801562+3'-UTR3.7631143.13063K562PUM2
chr7106800316106800351+3'-UTR3.8039319.46281K562PUM2
chr7106801275106801317+3'-UTR4.901048.25710K562IGF2BP1
chr7106800149106800269+3'-UTR5.9916137.47905K562IGF2BP1
chr7106800526106800552+3'-UTR3.064824.67716K562IGF2BP1
chr7106800925106800955+3'-UTR3.1138411.58341K562FAM120A
chr7106800935106801021+3'-UTR4.0217814.25675K562IGF2BP1
chr7106800518106800572+3'-UTR4.1182616.38760K562TIA1
chr7106801149106801259+3'-UTR3.3796429.85842K562FAM120A
chr7106801562106801623+3'-UTR5.19986400.00000K562PUM2
chr7106801738106801804+3'-UTR4.2416411.49791K562IGF2BP1
chr7106799929106800054+3'-UTR,CDS3.1218515.76561K562ZNF622
chr7106800783106800822+3'-UTR3.304604.88918K562IGF2BP1
chr7106800101106800168+3'-UTR4.6754414.81434HepG2SUB1
chr7106800882106800925+3'-UTR3.5565216.18067K562FAM120A
chr7106800061106800101+3'-UTR4.086568.50740HepG2SUB1
chr7106800300106800316+3'-UTR4.2014021.13627K562PUM2
chr7106799904106800061+3'-UTR,CDS3.1744810.13096K562ZNF800
chr7106800521106800559+3'-UTR3.732986.50688HepG2SUB1
chr7106799997106800059+3'-UTR,CDS3.582967.94404K562GRWD1
chr7106801405106801433+3'-UTR3.003114.74027K562YBX3
chr7106801021106801080+3'-UTR4.9455222.68660K562IGF2BP1
chr7106800996106801071+3'-UTR3.4468437.27671K562FAM120A
chr7106685163106685290+5'-UTR4.311867.89340K562DDX3X
chr7106685210106685344+5'-UTR3.676907.43702K562GEMIN5
chr7106768655106768722+CDS,intron-Proximal3.958708.25963K562LIN28B
chr7106762418106762450+CDS,intron-Proximal3.831678.08742K562LIN28B
chr7106786769106786871+CDS4.704099.87549K562LIN28B
chr7106685458106685468+CDS3.9104711.04556K562YBX3
chr7106768655106768687+CDS,intron-Proximal4.867455.70740K562ZNF800
chr7106797479106797494+CDS3.265884.35477K562UCHL5
chr7106685574106685660+CDS,intron-Proximal4.964756.35677K562SRSF1
chr7106685657106685708+CDS,intron-Proximal3.199633.07246K562AQR
chr7106685409106685447+CDS3.370913.58206K562LIN28B
chr7106685583106685655+CDS3.624266.92192K562UCHL5
chr7106792494106792580+intron-Distal3.134423.81590K562HNRNPL
chr7106773956106774082+intron-Distal3.131213.89829K562LSM11
chr7106782306106782366+intron-Distal3.346073.46531K562KHSRP
chr7106689215106689275+intron-Distal4.374827.56720K562PTBP1
chr7106713408106713452+intron-Distal4.271575.46313K562KHSRP
chr7106738009106738063+intron-Distal5.314058.69609K562EXOSC5
chr7106732693106732795+intron-Distal4.069213.09815K562IGF2BP1
chr7106737188106737220+intron-Distal5.3270210.01029K562EXOSC5
chr7106726152106726213+intron-Distal3.356025.57010K562KHSRP
chr7106738989106739043+intron-Distal3.8681312.17867K562HNRNPM
chr7106768774106768879+intron-Distal,intron-Proximal3.628783.06676K562U2AF2
chr7106792705106792781+intron-Distal4.039063.58835K562HNRNPK
chr7106697246106697301+intron-Distal3.214543.43875K562EXOSC5
chr7106739858106739903+intron-Distal4.068453.59909K562EXOSC5
chr7106732672106732801+intron-Distal4.8389215.23822K562TARDBP
chr7106791173106791220+intron-Distal4.164678.55611K562KHSRP
chr7106737797106737873+intron-Distal3.996259.69970K562EXOSC5
chr7106733623106733710+intron-Distal4.012016.41051K562EXOSC5
chr7106738981106739062+intron-Distal5.254728.69493K562EXOSC5
chr7106726213106726301+intron-Distal4.239368.11145K562KHSRP
chr7106735498106735538+intron-Distal4.288014.51377K562HNRNPM
chr7106705824106705864+intron-Distal3.683443.68558K562EIF4G2
chr7106786564106786622+intron-Distal3.043923.57054K562U2AF2
chr7106735728106735773+intron-Distal3.735284.61282K562EXOSC5
chr7106791220106791275+intron-Distal,intron-Proximal5.144686.94732K562KHSRP
chr7106791862106791933+intron-Distal3.635803.27944K562PTBP1
chr7106740894106740951+intron-Distal4.394493.59909K562EXOSC5
chr7106739043106739068+intron-Distal4.158904.03833K562HNRNPM
chr7106778492106778542+intron-Distal3.887055.03657K562PTBP1
chr7106794520106794591+intron-Distal3.805933.34609K562TARDBP
chr7106746814106746923+intron-Distal3.295384.43202K562HNRNPL
chr7106766957106766998+intron-Distal4.390768.89397K562ZC3H11A
chr7106693988106694069+intron-Distal4.4562111.24103K562TARDBP
chr7106732679106732769+intron-Distal4.864733.72755K562EIF4G2
chr7106741166106741217+intron-Distal4.396755.04209K562MATR3
chr7106737341106737427+intron-Distal5.6300213.95646K562HNRNPM
chr7106766879106766957+intron-Distal5.0506024.02975K562ZC3H11A
chr7106738872106738952+intron-Distal4.515273.72005K562MATR3
chr7106700146106700230+intron-Distal3.389613.69826K562TARDBP
chr7106737330106737423+intron-Distal6.8789529.42565K562EXOSC5
chr7106776416106776493+intron-Distal4.186804.97094K562SAFB2
chr7106736640106736690+intron-Distal5.214547.06134K562EXOSC5
chr7106732996106733080+intron-Distal5.8859714.07420K562KHSRP
chr7106735499106735537+intron-Distal5.138547.06134K562EXOSC5
chr7106697387106697439+intron-Distal4.007023.01445K562EXOSC5
chr7106768773106768819+intron-Proximal3.752914.95247K562PRPF8
chr7106768769106768824+intron-Proximal4.066784.95583K562RBM22
chr7106710669106710720+intron-Proximal4.824683.91589K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRKAR2B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRKAR2B is not available on ENCORE database.

  • 64 RBPs can affect the levels of PRKAR2B.  








The Knockdown/knockout RNA-Seq assay for PRKAR2B is not available on ENCORE database.





64 RBPs can affect the gene expression of PRKAR2B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRKAR2BENSG00000005249.821.930404.077102.427202.804602.02780HepG2CALR
PRKAR2BENSG00000005249.85690.154904468.532700.348603.535302.18430K562AARS
PRKAR2BENSG00000005249.89744.649208362.920900.220503.782503.13750K562AGGF1
PRKAR2BENSG00000005249.83614.815609328.24490-1.3677045.8588043.72210K562AQR
PRKAR2BENSG00000005249.83755.952304834.81560-0.364307.795606.15690K562BCLAF1
PRKAR2BENSG00000005249.83429.044704741.58630-0.467602.930702.03490K562BOP1
PRKAR2BENSG00000005249.85638.717808206.69630-0.541402.802901.73200K562CNOT7
PRKAR2BENSG00000005249.83752.144805041.78550-0.426205.192004.12450K562CPSF6
PRKAR2BENSG00000005249.85012.153004247.205600.238803.204701.89510K562DDX21
PRKAR2BENSG00000005249.85031.063006023.26740-0.259703.803601.66800K562DDX24
PRKAR2BENSG00000005249.84519.702005684.61730-0.330803.894602.62790K562DDX3X
PRKAR2BENSG00000005249.89874.307908378.158400.236904.016703.25080K562DDX47
PRKAR2BENSG00000005249.84779.406905763.38900-0.270103.688502.11890K562DDX6
PRKAR2BENSG00000005249.82844.492004179.52770-0.555206.966305.46600K562EFTUD2
PRKAR2BENSG00000005249.85276.799206243.79990-0.242803.788302.35380K562EIF2S1
PRKAR2BENSG00000005249.84629.345105821.66030-0.330604.196803.33840K562EIF2S2
PRKAR2BENSG00000005249.87442.484204475.322300.733709.412407.35210K562EIF3D
PRKAR2BENSG00000005249.82743.064005938.92430-1.1144030.5965027.51890K562EIF4A3
PRKAR2BENSG00000005249.813021.6859010590.379800.298105.591304.27690K562EIF4G2
PRKAR2BENSG00000005249.87040.359504244.773300.7299010.832208.43340K562FKBP4
PRKAR2BENSG00000005249.83447.411305129.66710-0.573407.998306.49870K562FMR1
PRKAR2BENSG00000005249.82867.399204347.75570-0.600507.513305.92990K562FTO
PRKAR2BENSG00000005249.86444.057204592.158300.488703.527601.99010K562FUS
PRKAR2BENSG00000005249.88784.154706179.177900.507402.512901.84510K562G3BP2
PRKAR2BENSG00000005249.81925.495204813.75940-1.3219030.8204028.01890K562GPKOW
PRKAR2BENSG00000005249.84739.845207758.52120-0.710908.611707.26020K562GRSF1
PRKAR2BENSG00000005249.82329.250904889.73260-1.0699031.7724029.81620K562HNRNPC
PRKAR2BENSG00000005249.82665.133804366.42270-0.7122013.9282011.38240K562HNRNPF
PRKAR2BENSG00000005249.86595.773408422.14230-0.352602.510201.54880K562IGF2BP2
PRKAR2BENSG00000005249.812087.208509235.075900.388202.324001.57700K562KIF1C
PRKAR2BENSG00000005249.86836.300108855.11040-0.373303.341402.41110K562MAGOH
PRKAR2BENSG00000005249.83715.335404698.72620-0.338803.754802.72370K562METAP2
PRKAR2BENSG00000005249.88233.5321011288.24280-0.455205.807804.17760K562MSI2
PRKAR2BENSG00000005249.84367.324405289.14200-0.276305.210904.12470K562MTPAP
PRKAR2BENSG00000005249.89917.624007251.507200.451603.077202.13930K562NAA15
PRKAR2BENSG00000005249.84847.669505930.50610-0.290903.566502.15390K562NCBP2
PRKAR2BENSG00000005249.83422.451404814.23290-0.492305.323803.10070K562NUSAP1
PRKAR2BENSG00000005249.84351.447207884.20230-0.857505.386503.64470K562PABPC1
PRKAR2BENSG00000005249.85268.512706480.97790-0.298802.569901.78410K562PPIG
PRKAR2BENSG00000005249.82598.869904384.12560-0.7544014.2904011.89830K562PSIP1
PRKAR2BENSG00000005249.85786.015708603.01260-0.572306.578405.58840K562PTBP1
PRKAR2BENSG00000005249.89202.3834011554.86450-0.328403.765402.81800K562PUF60
PRKAR2BENSG00000005249.87965.4815012042.15840-0.5963018.7164016.33780K562PUM2
PRKAR2BENSG00000005249.85312.262108251.32130-0.635305.224304.02670K562RBM22
PRKAR2BENSG00000005249.84798.003206276.73690-0.387604.576402.28630K562RECQL
PRKAR2BENSG00000005249.84648.447108357.97050-0.846404.567802.72390K562SFPQ
PRKAR2BENSG00000005249.83056.630003791.71260-0.310902.867101.81690K562SRFBP1
PRKAR2BENSG00000005249.84736.173505940.97910-0.327005.529104.26240K562SRPK2
PRKAR2BENSG00000005249.84435.404208433.39740-0.9270013.8593012.27530K562SRSF1
PRKAR2BENSG00000005249.82908.946803458.44240-0.249602.265601.33090K562SRSF4
PRKAR2BENSG00000005249.86277.250707963.66110-0.343302.262901.33150K562SRSF5
PRKAR2BENSG00000005249.89268.347107491.623000.306902.700301.35950K562SSRP1
PRKAR2BENSG00000005249.87750.6915010081.71460-0.379306.241104.10850K562SUCLG1
PRKAR2BENSG00000005249.83079.824303938.29120-0.354702.610001.62490K562SUPV3L1
PRKAR2BENSG00000005249.84780.343903245.306900.5587010.891009.26460K562SYNCRIP
PRKAR2BENSG00000005249.85342.904108536.06020-0.675906.965705.79270K562TARDBP
PRKAR2BENSG00000005249.86823.586708233.75450-0.271002.079301.37690K562TIA1
PRKAR2BENSG00000005249.83478.414604479.64820-0.365003.772802.63660K562TRIM56
PRKAR2BENSG00000005249.89000.3237013028.08110-0.533609.544107.14730K562UBE2L3
PRKAR2BENSG00000005249.83145.892304167.99240-0.405903.810402.59720K562UCHL5
PRKAR2BENSG00000005249.83980.199006231.25020-0.6467025.2583023.35300K562UPF1
PRKAR2BENSG00000005249.87091.631205544.503700.355004.535503.47060K562WDR43
PRKAR2BENSG00000005249.87547.8036011051.31080-0.5501010.067907.75140K562WRN
PRKAR2BENSG00000005249.81882.850304930.42110-1.388806.194403.62360K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRKAR2B is not available on ENCORE database.





10 RBPs can affect the splicing of PRKAR2B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.076000.000000.00000excludedK562SRSF1
SEPRKAR2BENSG00000005249.8chr7+106797640106797769106797428106797494106799893106802256-0.067000.000000.00004excludedK562SF3B4
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.122000.000000.00000excludedK562PRPF8
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.069000.000000.00002excludedK562AQR
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.051000.000000.00018excludedK562FXR1
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.052000.000000.00003excludedK562U2AF1
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.092000.000000.00000excludedK562U2AF2
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.088000.000000.00000excludedK562TARDBP
SEPRKAR2BENSG00000005249.8chr7+106797630106797711106797428106797494106799893106802256-0.094000.000410.02319excludedK562HNRNPK
SEPRKAR2BENSG00000005249.8chr7+106797630106797769106797428106797494106799893106802256-0.054000.000000.00007excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRKAR2B is not avaliable on ENCORE database.