LOXL1

General Information

Gene Name       : LOXL1
Gene ID             : ENSG00000129038.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: LOXL1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LOXL1ENSG00000129038.150.000.000.00ENCSR000AEF
HepG2LOXL1ENSG00000129038.150.340.390.36ENCSR985KAT
K562LOXL1ENSG00000129038.150.000.080.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LOXL1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LOXL1 RNA is bound by 4 proteins.  







eCLIP assay for LOXL1 is not avaliable on ENCORE database.





4 proteins are bound to LOXL1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr157422265374222657+intron-Distal5.719996.06289K562PUM2
chr157422266474222672+intron-Distal3.7208915.36456K562WRN
chr157422265774222672+intron-Distal5.719996.06289K562PUM2
chr157422265374222657+intron-Distal3.7208915.36456K562WRN
chr157422266174222672+intron-Distal3.375529.98301K562GNL3
chr157422266274222673+intron-Distal6.4869414.07636K562PABPC4
chr157422265374222661+intron-Distal3.375529.98301K562GNL3
chr157422265374222657+intron-Distal6.4869414.07636K562PABPC4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LOXL1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LOXL1 is not available on ENCORE database.

  • 7 RBPs can affect the levels of LOXL1.  








The Knockdown/knockout RNA-Seq assay for LOXL1 is not available on ENCORE database.





7 RBPs can affect the gene expression of LOXL1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LOXL1ENSG00000129038.110.000007.43240-99999.999991.983301.46900HepG2BOP1
LOXL1ENSG00000129038.1130.438907.736901.976002.758402.11800HepG2GPKOW
LOXL1ENSG00000129038.1133.836702.662203.667805.538804.67080HepG2MATR3
LOXL1ENSG00000129038.1127.725407.405701.904402.673802.08610HepG2PUF60
LOXL1ENSG00000129038.1124.589807.855601.646201.970001.39800HepG2PUM2
LOXL1ENSG00000129038.110.480709.54710-4.311702.313901.69250HepG2ZC3H8
LOXL1ENSG00000129038.1122.315204.586902.282302.625702.08930HepG2ZNF622
LOXL1ENSG00000129038.116.732500.0000099999.999902.094901.35440K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LOXL1 is not available on ENCORE database.






No RBPs affect the alternative splcing events of LOXL1 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for LOXL1 is not avaliable on ENCORE database.