PCBD2

General Information

Gene Name       : PCBD2
Gene ID             : ENSG00000132570.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PCBD2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PCBD2ENSG00000132570.144.393.684.04ENCSR000AEF
HepG2PCBD2ENSG00000132570.145.575.385.47ENCSR985KAT
K562PCBD2ENSG00000132570.145.054.564.80ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PCBD2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PCBD2 RNA is bound by 31 proteins.  







eCLIP assay for PCBD2 is not avaliable on ENCORE database.





31 proteins are bound to PCBD2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5134240765134240826+5'-UTR3.566483.25786HepG2FAM120A
chr5134261223134261273+intron-Distal4.389143.03671K562HNRNPM
chr5134253382134253461+intron-Distal5.388947.23521HepG2HNRNPM
chr5134260220134260297+intron-Distal5.09609400.00000HepG2DHX30
chr5134261566134261589+intron-Distal5.099547.09226HepG2GRSF1
chr5134260219134260290+intron-Distal3.0614042.87338K562SLTM
chr5134260254134260256+intron-Distal10.10195400.00000HepG2GRSF1
chr5134262721134262739+intron-Distal9.51645400.00000HepG2GRSF1
chr5134260921134260989+intron-Distal5.081894.74377HepG2FASTKD2
chr5134263417134263426+intron-Distal7.3087641.82217HepG2GRSF1
chr5134261601134261653+intron-Distal5.2364610.24747HepG2SUPV3L1
chr5134259780134259804+intron-Distal4.2238410.96815K562WRN
chr5134261064134261140+intron-Distal4.525727.32475K562HLTF
chr5134260218134260269+intron-Distal3.2709340.35106K562DDX52
chr5134261078134261130+intron-Distal3.626998.08839K562AGGF1
chr5134259713134259759+intron-Distal4.957256.08953K562EXOSC5
chr5134252665134252717+intron-Distal3.167983.43829K562EXOSC5
chr5134260212134260243+intron-Distal10.20360400.00000HepG2GRSF1
chr5134261607134261666+intron-Distal7.7386544.92113K562DHX30
chr5134259985134259989+intron-Distal4.067537.01333K562EXOSC5
chr5134260268134260271+intron-Distal8.58071400.00000K562FASTKD2
chr5134260219134260294+intron-Distal3.2214941.17833K562AGGF1
chr5134263426134263461+intron-Distal6.40090400.00000HepG2DHX30
chr5134261603134261657+intron-Distal4.6485213.29920HepG2FASTKD2
chr5134298135134298193+intron-Distal3.239893.06830K562UPF1
chr5134240950134241050+intron-Distal,intron-Proximal3.430706.03408HepG2DGCR8
chr5134261048134261170+intron-Distal3.430934.49566K562FUS
chr5134261589134261672+intron-Distal8.52543100.51761HepG2GRSF1
chr5134260243134260254+intron-Distal10.15328400.00000HepG2GRSF1
chr5134262708134262776+intron-Distal3.258799.57810K562ZC3H11A
chr5134262712134262778+intron-Distal4.2685830.20468K562ILF3
chr5134263407134263469+intron-Distal3.059556.72040K562AGGF1
chr5134263447134263456+intron-Distal9.98198400.00000K562FASTKD2
chr5134263437134263444+intron-Distal9.14516400.00000K562FASTKD2
chr5134263640134263670+intron-Distal4.579567.21749HepG2DHX30
chr5134260223134260293+intron-Distal4.39439400.00000K562ILF3
chr5134262724134262777+intron-Distal9.24724400.00000HepG2FASTKD2
chr5134262739134262777+intron-Distal9.60359400.00000HepG2GRSF1
chr5134260220134260295+intron-Distal5.7043586.82346K562SUPV3L1
chr5134262727134262777+intron-Distal3.979558.85861HepG2EIF3D
chr5134263631134263657+intron-Distal7.7143424.67718K562DHX30
chr5134260267134260270+intron-Distal9.09168400.00000HepG2FASTKD2
chr5134263420134263483+intron-Distal7.17447400.00000K562DHX30
chr5134263445134263483+intron-Distal3.494875.67364K562ILF3
chr5134260270134260302+intron-Distal9.18364400.00000HepG2FASTKD2
chr5134263444134263481+intron-Distal3.593048.39652K562HLTF
chr5134261766134261797+intron-Distal6.6831413.30225K562FASTKD2
chr5134259866134259911+intron-Distal4.6012954.00830HepG2DHX30
chr5134261089134261146+intron-Distal5.467166.84641K562DDX52
chr5134261332134261388+intron-Distal5.7201513.32329K562EXOSC5
chr5134262090134262149+intron-Distal4.030676.11008K562EXOSC5
chr5134259866134259910+intron-Distal6.5121217.03881K562SUPV3L1
chr5134263461134263479+intron-Distal8.92377125.38408HepG2FASTKD2
chr5134263448134263478+intron-Distal8.05312118.01791HepG2GRSF1
chr5134262718134262779+intron-Distal6.63233400.00000K562FASTKD2
chr5134259875134259915+intron-Distal3.083695.65103K562DDX21
chr5134261160134261208+intron-Distal3.733814.02190K562EXOSC5
chr5134253414134253467+intron-Distal4.749736.08953K562EXOSC5
chr5134253231134253290+intron-Distal5.4517110.73599HepG2HNRNPM
chr5134260203134260286+intron-Distal5.141289.77167K562AARS
chr5134297789134297862+intron-Distal3.691983.56210K562EIF4G2
chr5134246176134246269+intron-Distal,intron-Proximal4.343595.43878K562TIA1
chr5134278358134278460+intron-Distal4.311443.25538K562KHSRP
chr5134262764134262777+intron-Distal6.54404400.00000K562DHX30
chr5134263426134263482+intron-Distal5.718447.51800K562ZC3H11A
chr5134260214134260294+intron-Distal4.2847564.52745K562ZC3H11A
chr5134263429134263475+intron-Distal3.7223910.22418K562DDX52
chr5134263434134263444+intron-Distal4.616734.93822HepG2SUPV3L1
chr5134262722134262777+intron-Distal6.63186400.00000HepG2DHX30
chr5134263628134263673+intron-Distal6.3011916.75999HepG2FASTKD2
chr5134263430134263480+intron-Distal3.671433.65874K562LSM11
chr5134259867134259899+intron-Distal10.36909400.00000HepG2GRSF1
chr5134261092134261135+intron-Distal3.624967.65869K562MTPAP
chr5134259856134259883+intron-Distal3.9595541.87186K562ILF3
chr5134260221134260299+intron-Distal3.8992640.45557K562TBRG4
chr5134263444134263477+intron-Distal4.121163.53867K562TBRG4
chr5134261615134261646+intron-Distal6.8036414.59032K562FASTKD2
chr5134260260134260264+intron-Distal8.86978400.00000HepG2FASTKD2
chr5134260264134260267+intron-Distal9.06670400.00000HepG2FASTKD2
chr5134259173134259237+intron-Distal4.235283.30687K562EXOSC5
chr5134259869134259907+intron-Distal5.18176400.00000HepG2SUPV3L1
chr5134262713134262750+intron-Distal6.63770400.00000K562DHX30
chr5134259894134259903+intron-Distal6.80595400.00000K562FASTKD2
chr5134263632134263674+intron-Distal5.846456.96861HepG2SUPV3L1
chr5134284566134284666+intron-Distal4.462094.66899HepG2HNRNPM
chr5134260256134260260+intron-Distal9.88939400.00000HepG2GRSF1
chr5134260623134260665+intron-Distal4.775055.12432K562EXOSC5
chr5134263444134263483+intron-Distal6.1429722.37172HepG2SUPV3L1
chr5134260281134260300+intron-Distal6.42009400.00000K562DHX30
chr5134261083134261139+intron-Distal6.5926547.73125K562FASTKD2
chr5134263426134263448+intron-Distal6.8854954.47071HepG2GRSF1
chr5134260271134260298+intron-Distal8.65016400.00000K562FASTKD2
chr5134262718134262790+intron-Distal3.140714.66736K562TBRG4
chr5134253148134253284+intron-Distal5.4970310.53056K562HNRNPM
chr5134271861134271913+intron-Distal4.137116.86842HepG2U2AF2
chr5134253152134253231+intron-Distal4.443838.70378HepG2HNRNPM
chr5134260277134260281+intron-Distal6.50004400.00000K562DHX30
chr5134263430134263446+intron-Distal7.4680938.64470HepG2FASTKD2
chr5134260254134260270+intron-Distal6.41916400.00000K562DHX30
chr5134259860134259908+intron-Distal6.47001400.00000HepG2FASTKD2
chr5134260707134260751+intron-Distal5.115638.04096K562EXOSC5
chr5134260214134260302+intron-Distal7.71567400.00000HepG2SUPV3L1
chr5134263446134263461+intron-Distal9.12170135.96373HepG2FASTKD2
chr5134259885134259911+intron-Distal6.46555400.00000K562DHX30
chr5134263433134263437+intron-Distal8.84698400.00000K562FASTKD2
chr5134262713134262777+intron-Distal4.2749013.38861K562SUPV3L1
chr5134263632134263673+intron-Distal8.0002948.69004HepG2GRSF1
chr5134263416134263445+intron-Distal3.455574.91867K562ILF3
chr5134259857134259885+intron-Distal6.42649400.00000K562DHX30
chr5134241027134241080+intron-Distal3.780865.38772K562RBM15
chr5134261771134261800+intron-Distal4.822283.75581HepG2DHX30
chr5134259883134259913+intron-Distal3.8363943.16524K562ILF3
chr5134316766134316869+intron-Distal4.754323.91475K562PTBP1
chr5134261079134261145+intron-Distal4.566015.17223K562ZC3H11A
chr5134263446134263482+intron-Distal4.6892813.53574HepG2ILF3
chr5134263461134263482+intron-Distal6.31142400.00000HepG2DHX30
chr5134262722134262750+intron-Distal3.075719.50022K562DDX52
chr5134261602134261664+intron-Distal6.1878646.62580HepG2DHX30
chr5134261097134261128+intron-Distal8.6287186.51094K562DHX30
chr5134263429134263433+intron-Distal7.47151400.00000K562FASTKD2
chr5134259846134259867+intron-Distal10.39868400.00000HepG2GRSF1
chr5134253511134253549+intron-Distal4.007023.01456K562EXOSC5
chr5134254463134254595+intron-Distal4.716975.68226HepG2HNRNPM
chr5134260224134260299+intron-Distal3.0977017.88236K562HLTF
chr5134262723134262780+intron-Distal6.55098400.00000HepG2SUPV3L1
chr5134260260134260264+intron-Distal9.93453400.00000HepG2GRSF1
chr5134260270134260276+intron-Distal6.16476400.00000K562DHX30
chr5134263427134263483+intron-Distal4.640555.63000HepG2HLTF
chr5134260264134260293+intron-Distal9.81202400.00000HepG2GRSF1
chr5134259899134259912+intron-Distal9.65999400.00000HepG2GRSF1
chr5134263456134263466+intron-Distal10.05576400.00000K562FASTKD2
chr5134263657134263673+intron-Distal7.6662323.02007K562DHX30
chr5134259845134259901+intron-Distal3.108543.66597K562DDX52
chr5134260218134260296+intron-Distal3.1880228.66776K562GEMIN5
chr5134263420134263477+intron-Distal7.7934218.09861K562SUPV3L1
chr5134261569134261613+intron-Distal3.186975.98067K562EXOSC5
chr5134260218134260235+intron-Distal7.71214400.00000HepG2FASTKD2
chr5134260235134260260+intron-Distal8.78376400.00000HepG2FASTKD2
chr5134260219134260253+intron-Distal6.41948400.00000K562DHX30
chr5134263466134263483+intron-Distal10.12006400.00000K562FASTKD2
chr5134259877134259906+intron-Distal3.409324.40390K562TBRG4
chr5134260225134260268+intron-Distal8.45684400.00000K562FASTKD2
chr5134261096134261130+intron-Distal9.0393510.09039K562SUPV3L1
chr5134253383134253459+intron-Distal3.258745.59281K562HNRNPM
chr5134272033134272127+intron-Distal4.774935.07478HepG2U2AF2
chr5134261101134261140+intron-Distal4.791403.34098HepG2HNRNPM
chr5134262716134262776+intron-Distal3.4725411.92114K562MTPAP
chr5134259989134260023+intron-Distal5.474229.68215K562EXOSC5
chr5134240932134241007+intron-Proximal3.736515.26179K562XRN2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PCBD2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PCBD2 is not available on ENCORE database.

  • 41 RBPs can affect the levels of PCBD2.  








The Knockdown/knockout RNA-Seq assay for PCBD2 is not available on ENCORE database.





41 RBPs can affect the gene expression of PCBD2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PCBD2ENSG00000132570.10188.35440102.355400.879803.446502.39850HepG2ABCF1
PCBD2ENSG00000132570.10145.8689088.730700.717102.445601.71450HepG2CIRBP
PCBD2ENSG00000132570.1075.85920123.12340-0.698702.076501.47100HepG2CPSF6
PCBD2ENSG00000132570.10110.08870193.76580-0.815604.528603.61530HepG2DAZAP1
PCBD2ENSG00000132570.10166.31190103.220400.688102.614701.95220HepG2DDX21
PCBD2ENSG00000132570.10181.10370108.137300.743902.912502.27280HepG2DDX3X
PCBD2ENSG00000132570.10164.66490104.698700.653202.651401.98650HepG2DKC1
PCBD2ENSG00000132570.10131.8489076.293200.789202.324401.47720HepG2EEF2
PCBD2ENSG00000132570.10179.6614098.709600.863902.619601.99680HepG2EIF4A3
PCBD2ENSG00000132570.10369.10470238.381800.630704.663003.91990HepG2ETF1
PCBD2ENSG00000132570.10152.2042099.528600.612701.974601.38620HepG2FXR1
PCBD2ENSG00000132570.10173.7396098.008900.825803.436702.43760HepG2G3BP2
PCBD2ENSG00000132570.10104.27170176.49360-0.759303.652902.88530HepG2HNRNPL
PCBD2ENSG00000132570.10143.3337071.331701.006704.544803.36000HepG2HNRNPM
PCBD2ENSG00000132570.10206.2208088.068001.227403.564802.44870HepG2IGF2BP3
PCBD2ENSG00000132570.10157.1876094.420300.735202.409201.48450HepG2KHSRP
PCBD2ENSG00000132570.10226.5999099.563001.186407.108006.07270HepG2MAGOH
PCBD2ENSG00000132570.10143.1915083.680900.774902.842802.02360HepG2MSI2
PCBD2ENSG00000132570.10166.40780102.498200.699002.473601.87270HepG2NCBP2
PCBD2ENSG00000132570.10132.25250192.13990-0.538902.111701.44320HepG2NOL12
PCBD2ENSG00000132570.10168.74010106.279100.666802.973802.34800HepG2PCBP1
PCBD2ENSG00000132570.10164.35800108.147400.603702.370001.85720HepG2PTBP1
PCBD2ENSG00000132570.10203.38330111.469400.867505.382104.57430HepG2PUS1
PCBD2ENSG00000132570.10204.56420120.354000.765203.811903.19660HepG2NELFE
PCBD2ENSG00000132570.10165.44000112.100100.561402.102401.55550HepG2RECQL
PCBD2ENSG00000132570.10174.32410104.252100.741602.394001.64500HepG2RPS2
PCBD2ENSG00000132570.10120.7394062.503000.949803.124902.27640HepG2RPS3A
PCBD2ENSG00000132570.10248.49810117.520201.080207.701007.00420HepG2SRSF1
PCBD2ENSG00000132570.10330.31760195.377000.757506.214905.50290HepG2SSB
PCBD2ENSG00000132570.10182.43200105.640700.788103.927703.27830HepG2TAF15
PCBD2ENSG00000132570.10190.2414095.091801.000303.463602.27450HepG2TBRG4
PCBD2ENSG00000132570.10217.76740108.209101.008906.564905.85520HepG2TIAL1
PCBD2ENSG00000132570.1068.60520109.19720-0.670502.287601.76510HepG2TRIM56
PCBD2ENSG00000132570.10158.6172088.434000.842803.124902.45960HepG2U2AF1
PCBD2ENSG00000132570.10157.76280215.35280-0.448901.817501.33790K562AGGF1
PCBD2ENSG00000132570.1068.78270129.49130-0.912703.526902.64080K562CPSF6
PCBD2ENSG00000132570.10479.98420308.231300.638905.281304.00350K562EIF4G2
PCBD2ENSG00000132570.10274.89690149.172200.881805.017103.89680K562PCBP3
PCBD2ENSG00000132570.10197.20850114.424800.785202.789201.98400K562POLR2G
PCBD2ENSG00000132570.10233.03880336.30430-0.529202.760901.94570K562PUF60
PCBD2ENSG00000132570.1097.63060148.17960-0.601902.291101.51600K562SF3B4
PCBD2ENSG00000132570.10213.45520154.816800.463302.173801.41670K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PCBD2 is not available on ENCORE database.





10 RBPs can affect the splicing of PCBD2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPCBD2ENSG00000132570.10chr5+1342576311342578051342460241342461561342947291342948100.254000.000000.00015includedK562SRSF1
SEPCBD2ENSG00000132570.10chr5+134246024134246156134240809134240913134294729134294810-0.082000.004070.03932excludedK562AQR
SEPCBD2ENSG00000132570.10chr5+134257631134257805134246024134246156134294729134294810-0.136000.000070.00172excludedK562PUS1
SEPCBD2ENSG00000132570.10chr5+134257631134257805134246024134246156134294729134294785-0.115000.002520.04793excludedK562U2AF1
SEPCBD2ENSG00000132570.10chr5+1342576311342578051342460241342461561342947291342948100.168000.001310.07766includedK562HNRNPUL1
SEPCBD2ENSG00000132570.10chr5+134257631134257805134246024134246156134294729134294810-0.141000.000040.00301excludedK562UTP18
SEPCBD2ENSG00000132570.10chr5+134257631134257805134246024134246156134294729134294785-0.153000.000000.00008excludedK562U2AF2
SEPCBD2ENSG00000132570.10chr5+134257631134257805134246024134246156134294729134294810-0.139000.001320.03378excludedK562RBM15
SEPCBD2ENSG00000132570.10chr5+134257631134257805134246024134246156134294729134294810-0.109000.003400.06991excludedK562AGGF1
SEPCBD2ENSG00000132570.10chr5+1342576311342578051342460241342461561342947291342947850.199000.000070.00466includedHepG2HNRNPC
SEPCBD2ENSG00000132570.10chr5+1342576311342578051342460241342461561342947291342947850.303000.000300.00688includedK562HNRNPC
MXEPCBD2ENSG00000132570.10chr5+134257631134257805134278170134278289134246024134246156134294729134294785-0.448000.000950.019152includedK562U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PCBD2 is not avaliable on ENCORE database.